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TRUONG DAI HOC VAN LANG

Ngtreri ra äè
KHOA Y — D'UIQC (KS, và ghi ra h9 ten)
BQ MON DOC
ighutAw

DE THI LAN : Lin 1 El ; Lin 2 0

ThS. TALI Thi Minh
MON HQC: SINH HQC PHAN It'
s
Si TC: .3 Hge kSi: II. .Nam Hoc: 2018 — 2019 Tmong Khoa (BO m6n) du)*
(KS/ yr' ghi r6 ho ten)
Thai gian: 45 pha ; 60 phut 0; 90 phut 0; 120 phut 0
Hinh thirc thi: Viet ; Trac Nghiem E ;
Sixth vie'n dirge tham khao tai lieu kliOng? Co ; 'Chong E

HQ Ira ten: Diem

MSSV:
Lap:
Lieu 17: Danh dAu cau chgn: X; Bo cau da ch9n: CO; Chgn lai cau da bo: •
Mt I: Vi tn cac cacbon trong eau trim dm &rang deoxyribose trong 1 nucleotide dirge them
(tau phay vi:
Phan ter acid phophoric khong c6 nguyen tU cacbon.
Da danh dau chieu cta chdai polynucleotide.
D phan biet vgi the vi tri eUa nguyen tCr C va N trong cu trim dang yang dm base nitct.
Muc dich xac dinh vj tri gin acid phosphoric va base nitric.
Cau 2: Su da clang cüa phan dr acid deoxyribosenucleic duct quyet dinh
S6 lugng cUa cac nucleotide.
Than phan eUa the loai nucleotide tham gia.
Trat tu sap x6p cUa the nuleotide.
CAu true khong gian cila acid deoxyribosenucleic.
Tat cã du dung.
Cau 3: Su ban vring va de thU trong eau trite 'thong gian xoan kap caa DNA dirge dam bao

Cac lien kat phosphodieste gift the nucleotide trong chuOi polynucleotide.
Lien lc& giera cac base nita va duang deoxyribose.
S6 lugng the lien kat hydro hinh thanh gitra the base nita caa 2 mach.
Sr kat hgp oh DNA vgi protein histone trong cu frac cfa sgi nhcam sac the.
Sr lien kat gift the nucleotide.
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Cliu 4: DNA c6 eau trite kh6ng gian xclan kep dang yang khep kin dirge thay 6:
a. Vi khuan b. Lap the c. Ty the d. b va c &mg e. Ca a, b va
Ca' u 5: Th8ng tin di truyen dirge ma h6a trong DNA dueri
Trinh tv eüa cac acid phosphoric quy dinh trinh tizr ena the nucleotide.
Trinh tg cüa cae nucleotide teen gen quy dinh trinh ty cUa the acid amin.
Nguyen the bó sung trong cAu trac khong gian dm DNA.
Trinh tg cüa cac deoxyribose quy dinh trinh tv eUa cac base nita.
Cau 6: Hai mach DNA mai dirge hinh thanh duai tac dung eta enzyme polymerase dga tren 2
mach dm phan tu DNA err theo each:
Phat trien theo hireling tit 3' den 5' (dm mach indri).
That trier' theo huang tir 5' den 3' (dm mach meri).
MOt mach mai dirge tOng hop theo twang tir 3' den 5' can mach mai kia pilot trien theo
Song lir 5' d'en 3'.
Hai mach mori dirge tong hop theo hireling ngau nhien, toy theo vi tri tac ching cilia enzyme.
am 7: Su nhan doi dm DNA tren ca ser nguyen the bó sung c6 the dung:
Dam bao duy tri thong tin di truyen On dinh qua the the he'.
Sao lai chinh xac trinh tv cüa cac nucleotide tren mai mach cilia phan ter DNA, duy tri tinh
chat dc tnrng va M dinh cüa phan tir DNA qua cae the he.
G6p phan tar) nen hien tugng bien di to hap.
a va b dung.
a, b, c du dung.
Ca is 8: Chfre nang nao duai day dia DNA la Ichong thing:
Mang thong tin di truyen quy dint' sir hinh thanh cac tinh tang cfra ca the.
Trgc tiep tham gia vao qua trinh sinh tang h9p protein.
Nhan doi nham duy trl thong tin di truyen On dinh qua cac the he te bao va ca the.
Doing vai tr6 quan trgng trong lien Ma
Mang eac gene tham gia vao ca che dieu haa tong hop protein.
Cau 9: Hien tugng hoan vi gene xay ra do:
DOt bien chuyen doan tucrng ha gicra cac NST.
Hien arcing lap doan do trao d& cite° bat thuang giaa 2 NST Mang ding.
Hien tugng tip hgp va trao dói cheo dm cap NST Prang 'Jong a ky dAu lAn phan bap 1 dm
giam phan.
Hien tugng phan ly ngau nhien cUa the NST trong cap d'eng dang cUa ki sau ran phan bac) 1
phan bao giam nhiam.
Dot bien dao doan NST.

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 u 10: Wit clop mach don cUa phan dr DNA 05 trinh tv cac nucleotide nhtr sau: ...ATG CAT
GGC CGC A... trong qua trinh tv nhan doi DNA mai dugc hinh thanh ttr doan mach khuon nay
se 05 trinh tv:
a. ...ATG CAT GGC CGC A... b. ...TAC GTA CCG GCG T...
c....UAC GUA CCG GCG U... d....ATG CUT ACC GGC T...
alu 11: M6 ta nao sau day dung nhat va tRNA:
tRNA la 1 polyribonucleotide có só ribonucleotide tuang frng ved s6 nucleotide ten mai
mach dm gene cau toe.
tRNA la 1 polyribonucleotide g6m tit 80 dan 100 ribonucleotide ko tao xoin, mOt Mu tv do
can m'gt Mu mang acid amin.
tRNA la 1 polyribonucleotide gam -lir 80 den 100 ribonucleotide cuon xoin a mOt Mu tren ca
sâ nguyen tic 1)6 sung thvc hien tién tat ca the ribonucleotide eUa tRNA, mot Mu mang acid
amin Ara mOt Mu mang bØ ba cthi ma.
tRNA la 1 polyribonucleotide gam tir 80 den 100 ribonucleotide cuon xoin 6. mot Mu, c6
doan cac base lien kat theo nguyen the b6 sung va c6 nhang doan khong b6 sung tao nen GAG
thüy ton. MOt Mu tv do mang acid amin dc hieu va ntht thUy ten mang 1)0 ba &Si ma.
tRNA 05 dang mach don hay cuOn xoin mOt Mu yeti s6 ribonucleotide tir 160 den 1300,
a
nhfing tRNA nay se kat hgp vOi nhang protein dc hieu tao nen the tiau phan ribosome.
Cliu 12: Sr hinh thanh chuai polyribonucleotide dirge thtrc hien theo each sau:
Nh6m HO- et vi tri 3' cila ribonucleotide trade gin vao nh6m phosphate & vi tri 5' dm
ribonucleotide sau.
Nh6m HO- & vi tri 3' dia ribonucleotide sau gin vao nh6m phosphate & vi tri 5' dm
ribonucleotide three.
Phat trian chuai polyribonucleotide tit 5' den 3' hoc tir 3' den 5' mOt each ngau nhien.
Phat trian thus& polyribonucleotide tO 3' den 5'
b va d dUng.
Can 13: Chgn trinh tv thich hgp cua cac ribonucleotide dirge thng hop tir 1 gene c6 doan mach
ba sung voi mach goc la: "AGC TTA GCA"
a. AGC UUA GCA b. UCG AAU CGU
c. TCG AAT CUT d. AGC TTA GCA
u 14: Teen mach tong Op RNA tha gene, enzyme RNA polymerase da di chuyan theo
chieu:
a. lir 5' den 3' b. Tir 3' den 5'
c. Chiau ngau nhi8n d. Tir gicra gene tiEn ra 2 phia
flu 15: Phan tü mRNA dirge sao ra tir mach mang ma goc cua gene dirge ggi la:
a. BO ba ma sao b. Ban ma goc c. BO ba ma goc d. Ban ma sao G. BO ba di ma

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Cau 16: Su'giong nhau tong eau frac DNA va RNA la:
Trong tau trac caa cac don phan c6 cluang ribose.
Cu trim khong gian xoan kap.
Du ca, cac loai base nita A, U, T, G, C trong cku file dm the don phan.
CAu troc kh6ng duct bieu hien tren ca sey nguyen tac 136 sung.
M.& don phan duct kin tao bed 1 phan ttir H3PO4, 1 &rang 5 cacbon va base nita.
Cau 17: Ma di truyen ten mRNA duce doe theo:
M0t chieu tab 5' den 3'.
Mot chieu tir 3' den 5'.
Hai chieu tfty theo vj tri xUe tac dm enzyme.
Chieu ung vori vj tri tiep ;the elm ribosome vei mRNA.
Vj trito ma bo ba UAA.
Cau 18: Ba ma b0 ba nao duoi day la ba ma ve nghia lam nhiem vii bao hieu ket thac viec tang
hcp protein la:
a. AUA AUG UGA. b. UAA UAG UGA.
c. AUA UAG UGA. d. AAU GAU GUC.
Cau 19: Ma 1)0 ba m& du tren mRNA la:
a. AAG b. AUG c. UAA d. UAG e. UGA
Cau 20: Trong va sau qua trinh giai ma di truyen, ribosome se:
Tr& lai clang rRNA sau khi hoan thanh viec tang hap protein.
Bat du tie]) 'uric voi mRNA tit b0 ba ma UAG.
Tnrot tir dau 3' den du 5' tren mRNA.
Tach thanh 2 tieu phan sau khi hoan thanh vie giai ma.
Chi tham gia giai ma cho 1 loai mRNA.
Cau 21: Qua trinh giai ma ket thac khi:
Ribosome rai Ichai mRNA va tra lai clang AT do yeti 2 tieu phan ion va be.
Ribosome di chuyen den ma b0 ba UAG.
Ribosome gan acid amin vao vi tri cuei cling elm chutii polypeptide.
Ribosome flap xUe voi 1 trong cac ma 130 ba UAU, UAC, UCG.
Ribosome tiep xac voi 1 trong cac ma 1)0 ba UAA, UAG, UGA.
Cau 22: Trong qua trinh giai ma, acid amin den sau se duce gan \Tao chui polypeptide dang
duct hinh thanh:
Khi tieu phan ion va be cila ribosome tach nhau.
Trutt khi tRNA dm acid amin ke tnrac tach kh6i ribosome dued dang tu do.
Khi ribosome di lchoi b0 ba ma Ichai du.
Khi ribosome di chuyen 1)0 ba ma tiep theo.
Gift thorn cacboxyl ket hop vori thorn amin caa acid amin lee tnroc de hinh thanh 1 lien ket
peptide.
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Cau 23: Cae mA b0 ba khde nhau bdri:
So lacing cac nucleotide.
Thanh phAn the nucleotide.
TrAt to dm cac nucleotide.
a, b, va c dUng.
b va dung.
Cau 24: Trong qua trinh tOng hop RNA:
1 doan DNA Prong Cmg voi 1 gene se throe did° xoan.
Qua trinh tang hop RNA dugc dive hien tren 1 mach dm gene.
Nhieu phan dr RNA co the &roc tang hop to' cling 1 gene.
Sau lchi tang hop RNA, doan DNA dOng xoan lai.
TAt ca du chang.
Cau 25: Dan vi ctu troc co ban dm chuOi polypeptide la:
a. Nucleotide b. Ribonucleotide c. Acid amind. Glucose e. Polymerase
Cau 26: C al u triac xotn a dm mach polypeptide la cAu trim khong gian:
a. BAc 1 b. BAc 2 e. BAc 3 d. BAc 4 e. BAe 5
Cau 27: Thong tin di truyen &roc truyen dat Wang doi an dinh qua nhieu the he te ban la nho:
Hog dOng sao mA Gila DNA
Cu che to sao de DNA
Hog dOng nguyen phan, giam phan va tho tinh
b va e Chang
a, b \fa c dfing
Cau 28: Dua tren ea cite nhan MI dm DNA:
ChAt lieu di truyen throe duy tri an dinh qua cdc the he.
DOI ea cho so nhan doi cUa NST.
Tao dieu kin cho so xuAt hien dot bier' gen do sai sot trong qua trinh nican Mi.
a, b, va c Mng.
a va b (hang.
Cau 29: Trong qua trinh nhan doi, enzyme DNA polymerase:
Di chuyen cling chieu tren 2 mach eiraphAn tit DNA me.
Di chuyen ngtroc chieu tren 2 mach dm phan dr DNA me.
Di chuyen theo sau cac enzyme xue tac cho qua trinh than xoin va pha eac lie ket hydro.
GAn the doan okazaki lai vai nhau.
Cau 30: Chieu xoan elm cila mach polynucleotide trong cAu true dm phan to' DNA:
a. 'Er trai qua pith b. To' phai qua trai
c. Ngugc chieu kim &Ong ho d. ThuAn chiau kim dong Ito e. a vá c &mg

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 •
Can 31: Thanh phan nao c6 trong 1 operon:
a. Gen chi huy b. Gen Ichai Ong c. Gen eau trlic
d. Gen deal hoe e. Ca a va c f. Ca b va c
Can 32: Tai ban DNA a Eukaryote e6 sr phan bia vâi sr tai ban DNA a Prokaryote IA:
Chiau tai ban;
He enzyme tai ban;
Nguyen lieu tai ban;
S6 lugng dun vi tai ban;
Nguyen the tai ban.
Can tra
a.lva2 b.2va3 c. 2 va 4 d. 3 va 4 e.3va5
azu 33: Dun phan eau tao nen phan tir DNA:
a. Ribonucleotide b. Nucleotide c. Nucleosome d. Polynucleotide
Can 34: Noi dung chill yeti caa nguyen fac be sung trong eau tile DNA la:
Hai loai base cling loai kh6ng lien ket vai nhau.
Purin chi lien ket vai pirimidin.
MOt loai base ban (A, G) dirge ba vai ma base be (T,C) va ngugc lai.
Lugng (A+G) luon bang (T+C).
T9 le (A+G)/ (T+C) dac tning vai mi loai sinh vat.
Can 35: Nguyen the be sung dune the hien trong du trite caa:
1. DNA dang xoan kep; 2. DNA clang xoan don;
3. Can true RNA van chuyen; 4. Trong eau true protein.
Can trii lai:
a. 1 va 2 b. 1 \fa 3 c. 1 va 4 d. 2 va 3
Olu 36: Lien ket phosphodieste dune hinh thanh eta 2 nucleotide xay ra giaa cac vi tri
cacabon:
l' caa nucleotide triton va 5' dm nucleotide sau.
5' dm nucleotide tnrec va 3' dm nucleotide sau.
5' elm nucleotide triton va 5' dm nucleotide sau.
3' elm nucleotide not va 5' oh nucleotide sau.
Cau 37: Sir linh hoat trong the dang boat dOng chire nang dm DNA dirge dam bao bad:
Tinh ben yang elm cac lien kat phosphodieste.
Tinh yeti elm cac lien lc& hydro trong nguyen the bei sung.
Cu there khong gian xoin kep tha DNA.
Six &mg va tháo xoan elm sgi nhietrn sac the.
Ehremg kinh eUa phan tir' DNA.

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 .
Mt 38: Trot-1g qua trinh nhan doi tha DNA, enzyme DNA polymerase tde (long theo each sau:
Dva tren phan tir DNA cii d tao nen 1 phan tit DNA hoAn toan mai, theo nguyen tac
sung.
Enzyme di ehuyen song song nguge chiau tren 2 mach eita phan tit' DNA mg da hinh thanh
nen the phan tir DNA con bang each lap the nucleotide theo nguyen the ba sung.
Enzyme DNA polymerase chi c6 the the &ling tren mi mach dia phan tir DNA theo chisel.' 3'
clan 5'
Enzyme tdc dOng tai nhiau diam tren phan tir DNA da qua trinh nhan dOi than fa nhanh
chong han.
Cita 39: Doan Okazaki IA:
Doan DNA dirge thng hap mot each lien tve ten DNA cil trong qud trinh nhan
Mot phan ter RNA thong tin &rot sao ra tix mach kh6ng phai la mach dm dm gene.
Cdc doan DNA mai dute tong hgp thAnh timg doan ngan tren 1 trong 2 mach dm DNA cii
trong qua trinh nhan
Cdc doan RNA ribosome dirge tong hgp tir eac gene tha nhan con.
Can doan DNA mai &rot thng hop ten ce. 2 mach dm phan tix DNA cii trong qud trinh nhan
do i.
Cau 40: Phat bieu nAo duoi day IA khOng dung:
Ca cha nhan doi cilia DNA dat ca seY cho sr nhan doi tha NST.
Phan tir DNA (King xoic eve dai van kY dau 1 trong qud trinh phan bAo giam nhiam.
Cde lien kat phosphodieste gift cdc nucleotide trong elm& IA cde lien kat ban vitng do d6 tie
nhan dot bian phai c6 cuerng dQ manh mai c6 tha lam Anh huemg clan cAu toe DNA.
Viec lip ghop cat nucleotide theo nguyen the bap sung trong qua trinh nhan doi dam bao the
thong tin di truyan dirge sao lai mOt each chinh xdc.
'Chong phai chi co mRNA ma tRNA và rRNA dau dirge tong hap tir the gene ten DNA.
au 41: 1Chi sir dvng phucrng phap dinh lugng acid nucleic bang quang ph6 Icas, gia sir kat qua.
OD260nm = 0,9 se tuang img voi dung dich c6 nong do DNA sgi dOi IA:
a. 4,54ml b. 5,4gg/m1 c. 3,6igIml d. 6,3 p.g/m1
CIS 42: Mot dung dich acid nucleic dirge xem la sach (khong tap nhiam protein) lchi ti s6
OD260mni OD280nm nam trong khoang:
a. 0 — 0,8 b. 1 — 1,8 c. 1,8 — 2 d. Khong c6 dap an dCtng
Cau 43: Cde acid nucleic trong gel agarose s hien hinh dugi tia tir ngoai (UV) nhO• mOt h6a
chat c6 ten 1A:
a. Glycerol b. Bromophenol Blue c. SDS d. Ethidium bromide e. Triton IX
Cliu 44: Trong thge th, nguai ta kh8ng vugt qua bao nhieu chu kt cho 1 phan Ong PCR:
a.10 b.20 c.30 d.40 e.50
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4Pa/
Cau 45: Enzyme th6ng dung nhAt thuang dirge sir clung trong phan Ung PCR (Polymerase
Chain Reaction) la:
a. RNA polymerase b. Taq polymerase c. DNase d. Nuclease e. RNase
Cau 46: Trong phan img PCR (Polymerase Chain Reaction) sau 30 chulcSIthi sr khuech dai se
la bao nhi8u so voi s6 lucmg ban mAu ban du:
a. 102 b. 103 c. 104 d. 105 e. 106
OM 47: Trong phan (mg PCR phan ti r DNA thuerng dirge bier' firth ô nhia d6 Ichoang bao
nhieu?
a. 50 — 55°C b. 70 °C - 75 °C c. 90 °C - 95 °C d. 100 °C - 105 °C
Cau 48: Doi vài phuang phap lai ten pha fan, cac phuang phap thuang dirge sir dung la:
a. Southern blot b. Northern blot c. Dot blot d. Ca a va b e. ca a, b, va c
a
au 49: Phuong phap Southern blot dirge sir dung dinh luang loai phan tir nao?
a. DNA B. mRNA c. Protein d. Ca a va b e. Ca a, b, va c
Cilu 50: Phuang phap Dot blot sir dung de dinh lacing loai phan tü nao?
a. DNA B. mRNA c. Protein d. Ca a va b e. CA a, va c

HET.!.

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TRUCING ELM HQC VAN LANG
Ngtrai ra de
ICHOA Y DIfQc (Ky va ghi r6 he. ten)
BO MON DIEU DIYONG

DE THI LAN : Lan 1 El; LAn 2 0

MON HOC: SINH HQC PHAN TO' ThS. Tran Thi Minh

SO TO .2 Hoe kSt• II. .Nam Hoc: 2018 — 2019 Trutng Khoa (Be men) duyet
(KS) Nth ghi ro ho ten)
Thai gian: 45 phat ; 60 phut 0; 90 phut 0; 120 philt 0
Hinh thire thi: Viet ; Trac Nghiem ;
Sinh vien duct tham khao tai lieu khong? Co 0; Kh8ng

Ho va ten: Ditm
MSSV:
Lap:
Lieu 9: Danh dAu eau elicit X; BO eau a chip: 0; Chon lai eau da bo: 10

u I: Trong qua trinh hinh thanh dal polypeptide, nh6m phosphate dm nucleotide sau s gan vao
nucleotide lathe a vi tri:
a. Cacbon ally 3 Gila duang deoxyribose. b. Nhorn phosphate.
c. Oxy elm duemg deoxyribose. d. Cacbon thir nh&t cUa duamg deoxyribose.
azu 2: Lien ket phosphodieste dugc hinh thanh giea 2 nucleotide xay ra gitra the vi tri cacabon:
l' dm nucleotide tru6c va. 5' dm nucleotide sau.
5' cita nucleotide trudfc va 3' caa nucleotide sau.
5' caa nucleotide fru& vA 5' caa nucleotide sau.
3' dm nucleotide twat va 5' dm nucleotide sau.
Cau 3: Su linh hoat trong the dang hoat dOng chirc nang cue. DNA dirge Tam bao
Tinh ban yang cüa cac lien ket phosphodieste.
Tinh yeu cüa the lien ket hydro trong nguyen tAc be sung.
Cu toe khong gian xoart kap cila DNA.
Su clang va thao xonn cUa sgi nhiatm sac the.
Duang lcinh elm phan ter DNA.
Cau 4: Sixth vat c6 RNA dong vai tr6 IA vat chat di truyen 1A:
a. Vi Ichuan b. Vi rut c. MOt só loai vi khuan
d. Mot se loai Vi rut e. Tat ca eac th bac) nhan so
Cau 5: Trong qua trinh nhan doi dm DNA, enzyme DNA polymerase tdc dOng theo each sau:
Dua tren phan dr DNA di de tao nen 1 phan tir DNA hoAn toan mei, theo nguyen tac b6 swig.
Enzyme di chuyen song song ngugc chieu tren 2 mach dm phan dr DNA me de hinh thanh nen the
phan hi DNA con bang each lap the nucleotide theo nguyen the be) sung.
Enzyme DNA polymerase chi c6 the Me dOng tren m& mach cita phan tir DNA theo chieu 3' den 5'
Enzyme the dOng tai nhieu diem tren phan tU DNA de qua trinh nhan d6i din ra nhanh ch6ng hon.
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Cau 6. Doan'Okazaki la:
Doan DNA dirge tang hgp mOt each lien tve ten DNA ea tong qua trinh nhan
Wit phan tir RNA thong tin dirge sao ra tü mach kheing phai la mach gee cila gene.
Cat doan DNA =Si daft tOng hgp thanh tirng doan ngan ten 1 trong 2 mach caa DNA di trong qua
trinh than dol.
Cae doan RNA ribosome dirge teng hgp tir cac gene dm than con.
Cac cloth DNA mei dirge tOng hop ten ca 2 mach oh phan I-Cr DNA al tong qua trinh than dol.
Cau 7. Dinh nghla nao sau day ve gene la dUng nhAt:
MOt doan cUa phan tir DNA mang thong tin cho viec tOng hop mot protein quy dinh tinh tang.
MOt doan cña phan -I* DNA ehiu trach nhiem tong hop mot trong cae loai RNA hoe tham gia vao
co che dieu hôa tang hop protein.
MOt doan cUa phan ter DNA tham gia vao ea ch dieu Ma tang hop protein nhu gene dieu hoa, gene
khed hanh, gene van hanh.
Mot doan cüa phan dr DNA chiu trach nhiem tang hop mOt trong the loai RNA thong tin, van
chuyen va ribosome.
La mOt doan cUa phan lir DNA có chfre nang di truyen.
Cau 8: Phat bieu nao dued day khong dUng:
Cat doan okazaki sau khi dirge tang hop se gan lai vài nhau thanh 1 mach lien Mc dued tac dung dm
enzyme DNA ligase.
Seri dan Mu la mach don dirge tOng hgp lien tve tong qua trinh nhan doi tir mit:A mach dm DNA mg
ten do DNA polymerase di chuyen theo chieu tat dong elm cac enzyme thao xoan va pha vä lien kat
hydro.
Sy than dôi c6 the din ra a nhieu diem tren DNA.
Do ket qua dm sir than doi, 2 DNA m6i dirge tOng hgp tit DNA mg theo nguyen the ban bao thn.
Sgi di theo la the doan Okazaki throe tong hgp trong qua trinh nhan doi tir mOt mach dm DNA me,
tren do enzyme DNA polymerase di chuyen theo chieu the enzyme thao xoan va pha v6 cat lien ket
hydro.
Cau 9: Phat bieu nao dudd day la 'thong dung:
Co ehe nhan dog dm DNA dal ea so cho skr than doi cUa NST.
Phan tir DNA d6ng xoac eve dai vao kS, du 1 tong qua trinh phan bao giam nhiem.
Cae lien ket phosphodieste gift cac nucleotide tong chuOi la the lien ket ben vimg do do tac than
dOt bien phai co cueing dO manh mai cO the lam art hueng den eAu tire DNA.
Vic lAp ghop the nucleotide theo nguyen the 66 sung tong qua trinh nhan doi dam bao cac thong
tin di truyen dirge sao lai mOt each chinh xac.
Khong phai chi c6 inRNA ma tRNA va rRNA Mu &lye tOng hgp tix the gene ten DNA.
Cau /0: Su phan bit co ban trong eau trim gift cac loai RNA do the yeu to sau guy& dinh:
SO lugng, thanh phAn cac loai ribonucleotide trong cau true.
So lugng, thanh phan, tat hi the loai ribonucleotide va cAu trUe Icheng gian cilia RNA.
Thanh phAn va tat tv eat loai ribonucleotide.
Cau true Ichong gian cfra the loai RNA.
sO lugng the loai ribonucleotide.

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Cau 11:' Cu frác khong gian caa RNA c6 clang:
Mach thing.
Xoin kep tao beri 2 mach polyribonucleotide.
Xoin don tao nen 1 mach polyribonucleotide.
CO the cO mach thing hay xoin dun thy thuOc vao giai doan phat trien caa RNA.
CO the c6 mach thing hay xoin don thy thuOc theo mei loai RNA.
Chu 12: Six teng hgp RNA dugc thut hien:
Theo nguyen tac be sung teen 2 mach dm gene.
Theo nguyen tic ba sung va chi tren 1 mach dm gene.
Trong nhan dal vei mRNA, con tRNA va rRNA dugc tang hgp ngoai than.
Trong hach nhan di veri rRNA, mRNA dugc teng hgp 0 cac phan con lai caa nhan va tRNA dirge
tang hgp & ty the.
Trong qua tilt phan bao nguyen nhiem.
Cau 13: Chon ttinh t thich hgp cüa cdc ribonucleotide dugc teng hgp tir 1 gene c6 doan mach ba sung
vei mach gac la: "AGC TrA GCA"
a. AGC UUA GCA b. UCG AAU CGU c. TCG AAT COT
d. AGC TTA GCA e. TCG AAT COT
Cau 14: Qua trinh tang hop RNA xay ra 6:
a. Ky. trung gian b. KS' dau cUa nguyen phan c. sau cüa nguyen phan
d. cuei cUa nguyen phan e. giaa cüa nguyen pha.n
Cciu 15: N'Oi dung nao clued day dang:
mRNA mang thong tin cho viec teng hop 1 loai protein, hoat dOng dm RNA c6 the keo dai qua
nhi'eu the he ye bao.
rRNA kat hgp voi cdc protein dc hieu d hinh thanh nen nhang sgi nhiem sic.
tRNA dOng vai tr6 van chuyen acid amin, c6 the sir dung qua nhieu the he te bao va 1 tRNA co the
van chuyen nhieu acid amin.
mRNA mang th6ng tin cho viec teng hgp 1 loai protein, co thin gian Mn tai trong M bao tucmg
ngan.
tRNA thuc hien van chuyen acid amin dc hien, thin gian ton tai caa tRNA trong te bao la rat ngin.
Cliu 16: Cat rRNA duce tong hop chit yeu
a. Ribosome b. Ty the va lap the c. Trung the d. Hach nhan e. DNA trong than
Ctiu 17: Su giong nhau trong eau trac DNA va RNA la:
Trong ctu true dia cac don phan c6 duang ribose.
Cali true lcheng gian xoan kep.
Deu c6 cac loai base nita A, U, T, G, C trong cau trac eUa các dan phan.
Cau trim kh6ng dirge bieu hien tren to se. nguyen tic ba sung.
MiSci don phan dirge kien tao basi 1 phan th H3PO4, 1 duang 5 cacbon va base nita.
Cliu 18: Nhang tinh chat nao clued day !thong phai la tinh chat caa ma di truy'en:
Tinh pha bien
Tinh dc hieu
Tinh thodi h6a
Tinh ban bao tan
Tinh lien tuc trong trinh tv cUa cdc ma be ba.

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Cdu 19! MA di truyen tren mRNA dirge doe theo:
MOt chiau tit 5' den 3'.
Met chieu tt 3' den 5'.
Hai chieu thy theo vi tri the tac caa enzyme.
Chieu (mg yen vi tri tiep the caa ribosome vdri mRNA.
Vi hi c6 ma be ba UAA.
Cdu 20: Gia sir 1 gene chi dugc cAu tan tic 2 loai nucleotide G va C. Tren mach gee cua gene di the c6
da:
a. 2 loai ma be ba. b. 8 loai ma be ba. c. 16 loai ma be ba.
d. 32 loai md be' ba. e. 64 loai ma be ba.
Cau 21: Hien tugng sao chop ngugc la hien tugng:
Dugc gdp & mot so loai virut.
Xay ra chü yeu & vi khuan.
RNA lam mau de thug hgp DNA.
Protein dugc dung lam mu de sao ra gen ddc hieu.
a Nth c ding.
Cdu 22: Md be ba mer Mu teen mRNA la:
a. AAG b. AUG c. UAA d. UAG e. UGA
Cau 23: Hien tugng thoai haa ma la hien tugng:
MOt be ba ma hoa cho nhieu acid amin.
Cac be ba nam noti tip nhau ten gene ma khong goi len nhau.
Cac ma be ba c6 the bi det bien gene de hinh thanh nen be ba ma boa m&i.
Nhieu mA be ba ma' h6a cho cling 1 acid amin.
Cac Ma be ba khOng tham gia vao qua trinh ma hea cho the acid amin.
OM 24: Trong va sau qua trinh giai ma di truyen, ribosome se:
Tr& lai clang rRNA sau khi hoan thanh viec t8ng h9p protein.
BM Mu tip the vai mRNA tic be ba ma UAG.
Truqt tic Au 3' den du 5' troll mRNA.
Tach thanh 2 lieu phAn sau khi hoan thanh viec giai ma.
Chi tham gia giai ma cho 1 loai mRNA.
Cdu 25: RNA van chuyen mang acid amin m& Mu nen vao ribosome c6 be ba dói md la:
a. AUA. b. CUA. c. UAC. d. AUC. e. GUA.
Cr-2u 26: Su hoan thien cAu true khOng gian cUa chuai polypeptide & te bao nhan that xay ra dr:
Ty the va ltroi /lei chat.
Te bao chat va ludti nei sixth chat.
Be golgi va Firth noi sixth chat.
Lysosome va the yin.
Trimg the va thoi v6' sac.
Cau 27: Qua trinh giai ma kat thac khi:
Ribosome rai Ichoi mRNA va ter lai dang tu do voi 2 tieu phan Ian va bd.
Ribosome di chuyen den ma' be ba UAG.
Ribosome gan acid amin vao vi hi cuOi cang eUa chu6i polypeptide.
Ribosome tiep the voi 1 trong cac ma be ba UAU, UAC, UCG.
Ribosome tiep xac voi 1 trong cac md. be ba UAA, UAG, UGA.
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flu 28: Trong qua trinh giai ma, acid amin tv do:
Two tip den ribosome plmc xi-kJ cho qua trinh giai ma.
Den ribosome duoi clang ATP boat hea.
Dugc haat boa thanh dang boat deng nit ATP, sau de lien ket vai tRNA d.c hieu de tao nen phirc
hgp [acid amin-tRNA], qua trinh din ra duai tao dung dm the enzyme dc hieu.
Dugc gan vai tRNA nha enzyme dc hieu tao thanh phIrc hgp [acid amin-tRNA] de phvc \RI cho qua
trinh giai ma & ribosome.
Kat hqp voi tieu phan be caa ribosome de tham gia vao qua trinh giai ma.
tt 29: Trong ca the, protein luen &lye Crei mai qua qua trinh:
Tv nhan
'Peng hqp tir mRNA sao ra ta gen ten DNA.
Teng hqp truc Wei) tir mach gee dm gene.
Sao ma dm gene.
Dieu hea sinh tang hgp protein.
Cau 30: S6 ma be ba chiu trach nhiem ma boa cho cdc acid amin la:
a.20 b.40 c.61 d.64 e.32
Olu 31: Trong qua trinh tang hgp RNA:
1 doan DNA tuang áng ved 1 gene se dugc thdo xo&n.
Qua trinh tang hap RNA dirge thuc hien tren 1 mach dm gene.
Nhiau phan tir RNA c6 the dirge tong hop 'lir ding 1 gene.
Saukhi tang hap RNA, doan DNA deng xoan lai.
TAt ca du &mg.
Can 32: Trong pit tit RNA nguyen tac be' sung dirge thuc hien giaa:
A va U bang 3 lien ket hydro, G va C bang 2 lien ket hydro.
A va T bang 2 lien ket hydro, G va C bang 3 lien ket hydro.
A va T bang 3 lien ket hydro, G va C bang 2 lien ket hydro.
A va U bang 2 lien ket hydro, G va C bang 3 lien kat hydro.
A va G bang 2 lien ket hydro, T va C bang 3 lien kat hydro.
Can 33: Dan vi eau trite ca ban dm chuel polypeptide la:
a. Nucleotide b. Ribonucleotide c. Acid amin d. Glucose e. Polymerase
Ciz'u 34: Cac acid amin trong chu6i polypeptide duct nal vai nhau bang lien let:
a. Phosphodieste b. Peptide c. Hydro d. Ion e. Cao nang
Cm 35: Qua trinh tv sao cUa vi khuAn dirge thuc hien bad bao nhieu dcm vi sao chep?
a. 1 don vi sao chop b. 2 don vi sao chop c. 3 dcm vi sao chap
d. 4 don vi sao chep e. Nhieu don vi sao chop
Can 36: du tnic }thong gian bac 2 dm protein dirge gill yang bang:
Cac lien lc& peptide
Nguyen tAc be sung gitia cdc nucleotide
Cac lien ket hydro
Cac cat' ntii disulphate
Cac lien ket cOng hoa. tri
Mt 37: Qua trinh nhan del dm DNA can cluge ggi la:
1. Ty sao; 2. Sao ma; 3. Tai sinh; 4. Giai ma; 5. Sinh king hgp DNA; 6. Tai ban
Ctiu Ira loi:
a. 1 va 2 b.1,2va3 c. 2 va 4 d. 1, 5 va 6 e. 1, 3, 4, 5 14 6
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Cau 38:DNA la vat chat mang theng tin di truyen de tnmg cho m6i loai, thong tin My c6 nhiem vv:
Th6ng tin ve eau trac caa DNA qua cac the h'ed duy tri tinh dc thing caa. DNA.
Thong tin ve trinh tr sip xep cüa cac nuclrotide tren rnetii mach caa phan tEl DNA qua qua trinh nhan

Th6ng tin quy dinh eau trim cüa cac loai protein trong M back va do do quy dinh m9i firth trang va
tinh chat elm ca the.
Quy dinh thai diem nhan doi tha DNA va do do guy& dinh sir sinh san cüa te bao va pha trien tha
ca the.
Quy dinh thbi diem ve vi tri tang hop caa the loai RNA ding this chi phoi ca che dieu hóa sinh teng
hgp protein.
Cau 39: Thong tin di truyen dugc truyan dat tuang doi 6n dinh qua nhieu the he le bao la nher
Hoat deng sao ma dm DNA
Ca che tv sac caa DNA
Hoat deng nguyen phan, gam phan va thu tinh
b va c ding
a, b va c dimg
Cau 40: Gene dm 1 doan DNA lam nhiern vu:
Gene du trite mang theng tin guy dinh 1 loai protein.
Tham gia vao ca the dieu hba sinh ding hap protein qua vai tr6 dm the gene dieu h6a, khol deng,
van hanh.
Teng hap cac RNA van chuyen.
Teng hgp the RNA ribosome.
Tat ca du dung.
Cau 41: Cau trite dc thu caa mil protein do yeu t6 flan guy dinh?
a. Trinh tv the ribonucleotide trong mRNA. b. Trinh ttj the nucleotide trong gen eau true.
c. Trinh tv cac acid amin trong protein. d. Chirc nang sinh h9c dm protein.
Cau 42: Dua tren ca cher' nhan del tha DNA:
Chat lieu di truyen dirge duy tri 6n dinh qua cac the he.
gat ca s& cho su than doi caa NST.
Tao diet' kien cho sr xuat hien det bin gen do sai sot trong qua trinh nhan d8i.
a, b, va c dang.
a va b dang.
am 43: Trong qua trinh than doi, enzyme DNA polymerase:
Di chuyen cling chieu ten 2 mach caa. phan ta DNA me.
Di chuyen ngugc chieu tren 2 mach dm phan tir DNA me.
Di chuyen theo sau cac enzyme xac tee cho qua trinh than xoan va pha vOr the lie ket hydro.
Gan caz doan okazaki lai vOi nhau.
atu 44: Enzyme nao khOng tham gia qua trinh tv sao caa DNA:
a. Enzyme ligase b. Enzyme helicase c. Enzyme polymerase I, II, III
d. Enzyme peptidase e. Enzyme primase
Cal u 45: tling dung dm Icy thuat PCR (Polymerase Chain Reaction) la:
Tach va thu nhan acid nucleic tir te bac, mo deng vat va thve vat.
Sir dung kha nang hap phi; anh sang ctia acid nucleic de dinh tinh va dinh luong DNA.
Khuech dal in vitro só lugng vat chat di truy6n can co.
Tao dong in vitro tang s6 lugng te bao mong mu6n. HETI.

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