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Alcohol, Drugs, and
Impaired Driving
Alcohol, Drugs, and
Impaired Driving
Forensic Science and Law Enforcement Issues
Edited by
A. Wayne Jones
Jørg G. Mørland
Ray H. Liu
First edition published 2020
by CRC Press
6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742
Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume
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ISBN: 978-0-367-25162-8 (hbk)
ISBN: 978-1-003-03079-9 (ebk)
Typeset in Minion
by Lumina Datamatics Limited
In Fond Remembrance of Two Inspirational Leaders
in Traffic Safety and Police Science on Two Continents
Foreword xi
Preface xiii
Editors xvii
Contributors xix
Section I
HISTORY OF DRIVING UNDER THE INFLUENCE
Section II
OTHER HISTORICAL EVENTS OF INTEREST
Section III
FORENSIC ISSUES INVOLVING ALCOHOL
vii
viii Contents
Section IV
USE OF NON-ALCOHOL DRUGS
AND IMPAIRED DRIVING
Section V
EPIDEMIOLOGY, ENFORCEMENT,
AND COUNTERMEASURES
Index 691
Foreword
xi
xii Foreword
(where the Borkenstein Alcohol Course continues to this day, recently celebrating its 60th
anniversary), Dr. Borkenstein influenced the lives of many of the major contributors to the
field of traffic safety. Among others, Dr. Doug Lucas, an internationally renowned Canadian
forensic scientist and director emeritus of the Centre of Forensic Sciences in Toronto, spear-
headed introduction of the Borkenstein Breathalyzer® instrument in his home province and
throughout the country. Indeed, Breathalyzer results served as the primary evidence for
prosecuting drunken drivers throughout the United States, Canada, and Australia.
Dr. Ray Liu, who has been the editor-in-chief of the influential journal Forensic Science
Review (FSR) for over 30 years, was a graduate student of Borkenstein and did an intern-
ship under Dr. Lucas in Toronto. Later, Dr. Liu was appointed professor and head of the
Forensic Science Program at the University of Alabama, Birmingham, where he is currently
professor emeritus. Dr. Liu has been continuously working with his mentor Dr. Ko-wang
Mei (1918–2016), retired president of the Taiwanese Central Police University, and younger
colleagues in further development of forensic science in his native Taiwan.
The network of influential scientists and policy makers contributing chapters to this
book devoted to the subject of alcohol, drugs, and impaired driving will help to raise the
profile of this important public health and safety issue. These individuals have already
made significant contributions through their writings and research and have encouraged,
trained, and/or mentored many of today’s leaders in the field.
This book is a compilation of peer-reviewed articles previously published in FSR, most
of which have been updated to include recent developments and current status of the subject
matter. In addition, several new articles are included from the July 2019 and January 2020
issues of the journal. The readers of this book owe a debt of gratitude to the authors of the
various chapters for their career-long contributions to the field of alcohol, drugs, and traffic
safety. Others can trace their introduction to the subject of impaired driving to attending vari-
ous ICADTS meetings and also as participants at the Borkenstein Alcohol and Drug Courses.
Most of the advances in road-traffic safety made in the United States, especially in the
1960s to 1980s, have a direct link to Dr. Borkenstein and the Center for Studies of Law
in Action, which he founded at Indiana University. I attended the Borkenstein Alcohol
Course as a student and novice researcher in 1990, and today I am proud to serve as its
executive director.
The many and sustained contributions made by Dr. Borkenstein have had a major
impact on the field of traffic safety, both in the United States and internationally, which is
reflected in the narrative of various chapters in this book. First and foremost, he invented
the Breathalyzer® instrument in 1954, which became the principal means of enforcing
drunk-driving laws throughout North America when traffic offenders were prosecuted.
In 1963–1964 Dr. Borkenstein led a team of researchers that produced the landmark
“Grand Rapids Study,” an epidemiological survey of crash risk in relation to a drivers’
blood- and breath-alcohol concentration. There is no doubt that Dr. Borkenstein’s efforts
helped to change public opinion about drinking alcohol before driving, and his legacy
continues to inspire new research initiatives in the on-going fight to improve traffic safety.
The contents of this book were derived from articles previously published in Forensic
Science Review (FSR), an international peer-reviewed journal established in 1989 to pub-
lish invited review articles covering all aspects of the forensic sciences. To commemorate
FSR’s over 30 years of continuous publication, the July 2019 issue was devoted to the subject
of “Alcohol, Drugs, and Impaired Driving.” Three of the articles from this special edition
of FSR are included in the book. Other chapters are updated versions of selected articles
previously published in FSR on the subject of alcohol, drugs, and driving. Some authors
made extensive revisions and opted to modify the titles of the articles published as book
chapters.
Forensic science is a multidisciplinary subject dealing with the application of a wide
range of scientific methods and techniques for the investigation of criminal offenses by
examination of physical and biological evidence. This interaction between science and law
makes the discipline of impaired driving and the use of chemical evidence for prosecution of
traffic offenders an important sub-domain of the forensic sciences. The main key words for
the chapters included in this book are:
**********
Sir Winston Churchill (1874–1965) is claimed to have said “Those who fail to learn from his-
tory are doomed to repeat it.” Others have added that in order to understand any scientific
discipline you need to know its history. With this sound advice, we are keen to acknowledge
the individuals who were instrumental in advancing knowledge about impaired driving
and improving the way that traffic offenders are prosecuted. One man in particular deserves
special mention and that is Professor Robert Frank Borkenstein (1912–2002), Department
of Criminal Justice, Indiana University (Bloomington, IN, US). Dr. Borkenstein served as
president of the International Council on Alcohol, Drugs, and Traffic Safety (ICADTS)
between 1969 and 1983. On the occasion of the 6th ICADTS meeting held in Toronto in
1974 Dr. Borkenstein became the third recipient of the prestigious Widmark award.
When Dr. Borkenstein died, obituaries appeared in several scientific journals as well as
national and international newspapers, exemplified by the New York Times, The Washington
Post, The Times of London, The Independent (UK), The Guardian (UK), The Economist, and
even Time Magazine. A summary of the life and work of Dr. Borkenstein, with focus on
the man and his impact was written by his friend and colleague from Toronto, Dr. Douglas
Lucas, whose tribute is included as Chapter 2 in this book.
Dr. Borkenstein made two fundamental contributions to the field of alcohol and traffic
safety. The first was the development of the Breathalyzer instrument in 1954, the availability
xiii
xiv Preface
of which simplified and strengthened the scientific evidence necessary for successful prosecu-
tion of drunken drivers. The Breathalyzer was approved for use by police forces in Australia,
Canada, and throughout the US. The wide acceptance and approval of the Breathalyzer
prompted police authorities to allocate more resources in the fight against drunken driving
and intensify their efforts to remove drunken drivers from the roads and highways.
The second major contribution made by Dr. Borkenstein was to the design and execu-
tion of a large-scale epidemiological study to determine the risk of involvement in a traffic
crash in relation to a driver’s blood-alcohol concentration (BAC). This became known as
the “Grand Rapids Study” named after the city in Michigan where a roadside survey of
drivers was conducted in 1963 and 1964. In this case-controlled study, the Breathalyzer
instrument was used to test drivers involved in crashes and compare results with a control
group of motorists not involved in crashes. The latter group was matched in various ways
in terms of demographics and other variables with the drivers involved in crashes.
**********
This first part of the book (Section I) consists of a single chapter (Chapter 1) that looks back
at historical developments in drunk and drugged driving legislation worldwide. Although
driving under the influence of alcohol is as old as motor-driven transportation dating to
the start of the twentieth century, the impairment caused by other drugs did not attract
much attention until the 1950s. Driving under the influence of non-alcohol drugs then
became a separate criminal offence and proof of impairment depended on the results
of clinical tests of impairment done by a physician or police surgeon. More recently, the
concept of establishing concentration per se limits in blood, as done with BAC, has been
extended to cover other psychoactive substances, both prescription medications and illicit
recreational drugs of abuse.
The second part of the book (Section II) comprises three chapters of historical inter-
est and important events, including a tribute to the life and work of Professor Borkenstein
(Chapter 2) and a chapter by Patricia Waller, PhD (Chapter 3) dealing with the Grand Rapids
Study. She emphasizes that driving with BAC above 0.04% is definitely associated with an
increased crash risk. The probability of a crash increases rapidly as BACs reach 0.08%, and
is extremely high at 0.15%. Single vehicle crashes were more common in drivers with higher
BAC as was the severity of their injuries and material damage was also more extensive.
Dr. Waller was an authority on the subject of injury prevention in connection with
traffic safety research. She was among a group of experts invited to attend a symposium
held in Taipei, Taiwan on December 1–2, 1999 to honor the many contributions made
by Dr. Borkenstein to traffic safety research. In honor of Dr. Waller (1932–2003) and her
contributions to the field of traffic safety research, we include an unabridged version of her
article in this book.
Chapter 4 presents a historical survey of the evolution of qualitative and quantitative
methods for the determination of ethanol in blood and breath for legal purposes.
The third part of the book (Section III) focuses primarily on driving impairment
caused by excessive drinking and the enforcement of BAC per se laws. The first chapter
Chapter 5 discusses the pros and cons of BAC as evidence for prosecuting traffic offenders
compared with methods of breath-alcohol analysis for evidential testing. The latter are
more convenient and non-invasive; they provide on-the-spot results and permit making
decisions about whether a driving permit should be revoked or a vehicle impounded.
Preface xv
The technology available for breath-alcohol analysis has improved considerably since
the days of the Breathalyzer, and the use of micro-processors allows automated sampling of
breath, detection of mouth alcohol, and calibration control of the accuracy of results, etc.
The performance of modern instruments for breath-alcohol analysis matches the accuracy
and precision of BAC determinations by gas-liquid chromatography. Nevertheless, results
of forensic breath-alcohol analysis are more often challenged in a legal context, probably
because of the weight given to this type of chemistry-based evidence in drunken-driving
litigation.
Chapter 6 reviews the merits of common defense arguments and court decisions
reached when scientific evidence in drunken driving cases is challenged. Because of the
importance attached to the results of blood- and breath-alcohol testing, the analytical
methods used require careful validation using rigorous quality assurance (QA) proce-
dures to ensure that the methodology is fit for its intended purpose. The background and
statistical methods applied in QA of forensic breath-alcohol testing are included in this
section as Chapter 7.
Chapter 8 is a forensic primer on the subject of ethanol pharmacokinetics. Aspects
of absorption, distribution, metabolism, and excretion of alcohol often arise in a typical
drunken-driving prosecution. For example, this might entail comparing BAC with the
quantity of alcohol a person admits drinking before driving. Another common request is
to perform a back calculation of BAC from time of sampling blood to an earlier time, such
as the time of driving, which is often several hours earlier. The practice of back-calculating
a person’s BAC is a mandatory requirement in some jurisdictions, and this requires knowl-
edge of the many factors influencing the clinical pharmacokinetics of ethanol.
The final chapter (Chapter 9) in Section III deals with the increasing use of biomarkers
to detect heavy drinking and the use of this information in forensic casework. Use of bio-
markers is particularly important when dealing with repeat offenders because many suffer
from an alcohol-use disorder and might clinically be diagnosed as being alcohol depen-
dent. Before these individuals are sentenced, and when they apply for relicensing, objective
evidence of their current drinking habits is obviously important. This can be achieved by
the determination of various biomarkers, including liver enzymes (AST, ALT, and GGT),
and other markers, such as MCV, CDT, EtG, and Peth.
The fourth part of the book (Section IV) shifts the focus toward the role played by
drugs other than alcohol in causing driver impairment. Although drunken driving is the
more serious problem for road-traffic safety, the prevalence of drivers impaired by non-
alcohol drugs is rapidly increasing. Inappropriate use of prescription medications (such
as sleep aids, anti-anxiety agents, and pain medications), as well as other drugs active in
the central nervous system are hazardous for traffic safety. Added to this is the problem of
taking psychoactive recreational drugs for pleasure and excitement, such as central stimu-
lants (amphetamines and cocaine) and cannabis/marijuana. The latter represents a serious
challenge for traffic safety because of the emphasis on legalizing/decriminalizing its use
in some jurisdictions. Chapter 10 gives a broad overview of driving under the influence
of non-alcohol drugs and the state of knowledge until the end of the twentieth century.
Chapters 11 and 12 update this knowledge to the twenty-first century and delve deeper
into experimental and epidemiological studies of impairment caused by certain classes
of psychoactive drugs, which are over-represented in crash statistics. The quantitative
relationships and the strength of the evidence relating impairment of body functions and
the concentrations of active substances in blood are reviewed in depth. The final chapter
xvi Preface
(Chapter 13) in Section IV looks at international trends in alcohol and drug use among
motor vehicle drivers, the prevalence of road traffic crashes (RTC) involving impaired
drivers, and the importance of study design, law enforcement strategies, and the toxico-
logical methods used to confirm intake of impairing substances.
The final part of the book (Section V) is concerned with the epidemiology of impaired
driving and the choice of enforcement strategies to deter traffic offenders and reduce their
involvement in road traffic crashes. Revocation of driving permits is not always effective,
because many drivers—especially hardcore offenders—continue to drive even without a
valid license. Chapter 14 attempts to place alcohol-impaired driving in a public health per-
spective and underscores the importance of enforcing concentration per se alcohol limits
for driving and paying more attention to improving the detection and prosecution of traf-
fic offenders.
The relationship between alcohol/drug use and impairment can be assessed in vari-
ous ways and with different types of methodological approaches. This is the subject of
Chapter 15, which explores the relevance of controlled laboratory studies of drug influ-
ence, the use of computer software and driving simulators, as well as on-the-road driving
tests under real-world conditions. These different methodologies have certain advan-
tages and limitations. For safety and ethical reasons, human dosing studies are limited to
therapeutic amounts of the medication, often a single acute dose, which is unlike many
apprehended drivers who overdose and also combine multiple psychoactive substances.
The authors present unequivocal evidence of the impairment effects of various classes of
drugs on skills necessary for safe driving, and they reiterate the importance of toxicologi-
cal analysis of blood samples from all victims of road traffic crashes, thus furnishing real-
world case studies.
The final two chapters in Section V take a closer look at the effectiveness of various sanc-
tions to deter and diminish driving under the influence of alcohol and/or drugs. Foremost
among these, in the case of alcohol, is the fitting of ignition interlock devices to vehicles
owned by a convicted drunken driver (Chapter 16). This necessitates that a person must pass
a breath-alcohol test before being able to start and drive their vehicle. This approach has
proven particularly effective in reducing recidivism among hard-core traffic delinquents.
The final chapter (Chapter 17) looks at various approaches for reducing impaired driving,
such as evidence-based legislation, more effective law enforcement deterrence strategies, and
options for different ways of sentencing, including drug or DUI courts and mandatory treat-
ment and rehabilitation programs in lieu of jail for a DUI or DUID conviction.
Professor A. Wayne Jones earned a BSc degree (1969) and a PhD degree (1974) in chemis-
try from the University of Wales (Cardiff, UK). In 2013 Dr. Jones retired from his appoint-
ment as senior scientist at Sweden’s National Laboratory of Forensic Medicine, Division of
Forensic Genetics and Forensic Toxicology (Linköping, Sweden). He currently serves as a
guest professor at the Department of Clinical Pharmacology, Division of Drug Research at
University of Linköping, Sweden.
Prof. Jones’s doctoral thesis was entitled “Equilibrium Partition Studies of Alcohol in
Biological Fluids” which dealt with analytical and physiological aspects of ethanol analysis
in blood and exhaled breath. Since 1973, his research activities have involved studies of the
pharmacology and toxicology of ethanol and other drugs of abuse. He has been particu-
larly interested in the determination of ethanol and drugs in biological specimens from
living and deceased persons, as well as the disposition and fate of psychoactive substances
in the body and their detrimental effects on performance and behavior. Dr. Jones received
a senior doctorate degree (DSc) from the University of Wales in 1993 for his body of pub-
lished work entitled: “Methods of Analysis, Distribution and Metabolism in the Body and
Biological Effects of Alcohol and Narcotics.”
Since his first publication in 1974, Dr. Jones’s name now appears as author or co-author
on more than 400 journal articles, reviews, and book chapters, most of which were pub-
lished in peer-reviewed journals. His publications are widely cited in scientific articles, and
also in court cases involving driving under the influence of alcohol and/or other drugs.
In recognition of his career-long contributions to the field of forensic science and toxi-
cology, Dr. Jones has received numerous awards including the Widmark Award from the
International Council on Alcohol, Drugs and Traffic Safety (ICADTS) in 1997.
Professor Jørg G. Mørland earned an MD degree from the University of Oslo in 1967
and a PhD degree in pharmacology from the same university in 1975. Dr. Mørland is
now a senior scientist at the Division of Health Data and Digitalization of the Norwegian
Institute of Public Health and a professor emeritus at the University of Oslo.
Throughout his professional career, Dr. Mørland has served as professor of pharmacol-
ogy at the University of Oslo and the University of Tromsø (Tromsø, Norway), director of
the former Norwegian National Institute of Forensic Toxicology, and was director of the
Division of Forensic Medicine and Drug Abuse Research of the Norwegian Institute of
Public Health (Oslo, Norway) until 2012.
He is a medical specialist in clinical pharmacology. His main research field is biomedi-
cal effects of alcohol and drugs of abuse, their metabolites and metabolism. He has been
the principal supervisor for approximately 30 PhD students, as well as the scientific project
manager for several projects supported by the Research Council of Norway.
Dr. Mørland has published more than 400 articles in peer-reviewed journals on phar-
macology, toxicology, forensic medicine, neuroscience, alcoholism, epidemiology, drug
analysis, and road-traffic safety. He has also written more than 8,000 expert-witness
xvii
xviii Editors
statements for the police and courts in Norway and has appeared hundreds of times as an
expert witness in courts at all levels in Norway as well as in some Swedish courts.
He was the recipient of a Widmark Award from the International Council on Alcohol,
Drugs and Traffic Safety (ICADTS) in 2004.
Professor Ray H. Liu began his career with a degree in law (1965) from the police acad-
emy (now Central Police University) in Taiwan before earning a PhD (1976) in chemis-
try from Southern Illinois University (Carbondale, IL). Before his doctoral thesis, Dr. Liu
studied forensic science under the guidance of Professor Robert F. Borkenstein at Indiana
University (Bloomington, IN) and received internship training at the Centre of Forensic
Sciences in Toronto, Canada, headed by Dr. Doug Lucas.
Dr. Liu has held positions at the University of Illinois at Chicago (Chicago, IL), the
US Environmental Protection Agency’s Central Regional Laboratory (Chicago, IL), and
the US Department of Agriculture’s Eastern Regional Research Center (Philadelphia, PA)
and Southern Regional Research Center (New Orleans, LA). He was a faculty member
at the University of Alabama at Birmingham (UAB) for 20 years (serving as the director
of the University’s graduate program in forensic science for the last 10 years) before his
retirement in 2004; he was granted professor emeritus status in 2005. Following his retire-
ment from UAB, Dr. Liu taught at Fooyin University (Kaohsiung, Taiwan) for 8 years
(2004–2012).
Dr. Liu’s scientific works have been mainly in the field of analytical and toxicologi-
cal chemistry of drugs of abuse (criminalistics and forensic toxicology), with a significant
number of publications in each of the following areas: enantiomeric analysis, quantitative
determination using isotopic analogs as internal standards, correlation of immunoassay
and GC-MS test results, specimen source differentiation, and analytical method develop-
ment. He has authored/edited (or coauthored/coedited) approximately 150 journal articles,
book chapters, and 5 books. Dr. Liu has long served as editor-in-chief of Forensic Science
Review and is a member of the editorial boards for several international journals.
Contributors
xix
History of Driving
Under the Influence I
Driving Under the Influence
of Psychoactive Substances
A Historical Review* 1
A. WAYNE JONES, JØRG G. MØRLAND,
AND RAY H. LIU
Contents
1.1 Introduction 4
1.1.1 Early Development 4
1.1.2 First Conviction for Impaired Driving 5
1.2 Alcohol, Drugs, and Crash Risk 6
1.2.1 Role of Alcohol 7
1.2.2 Role of Other Drugs 10
1.3 Impaired Driving Legislation 12
1.3.1 Alcohol 12
1.3.1.1 Clinical Tests of Drunkenness 14
1.3.1.2 Alcohol Concentration per se Limits 15
1.3.2 Non-alcohol Drugs 16
1.3.2.1 Clinical Tests and Impairment Laws 19
1.3.2.2 Drug Recognition Experts 19
1.3.2.3 Zero-Tolerance Laws 20
1.3.2.4 Drug Concentration per se Limits 21
1.3.2.5 Graded or Enhanced Penalties 24
1.4 Synthetic Drugs and Pharmaceuticals 26
1.4.1 Development of Synthetic Drugs 26
1.4.1.1 A Plethora of Pharmaceuticals 26
1.4.1.2 Scheduled Drugs and Controlled Substances 27
1.4.1.3 Public Awareness and Information 27
1.4.2 Upsurge of Recreational Drugs 29
1.4.2.1 Historical Background 29
1.4.2.2 Abuse of Illicit Drugs 30
1.5 Analytical Methods 31
1.5.1 Roadside Screening Tests 32
1.5.1.1 Standardized Field Sobriety Tests 32
1.5.1.2 Breath Tests for Non-alcohol Drugs 34
1.5.1.3 Oral Fluid Tests 34
1.5.2 Quantitative Analysis of Ethanol and Other Drugs 35
1.5.3 Interpretation of Analytical Results 37
* This chapter is an updated version of a review article previously published in Forensic Science Review:
Jones AW, Mørland JG, Liu RH: Driving under the influence of psychoactive substances—A historical
review; Forensic Sci Rev 31:103; 2019.
3
4 Alcohol, Drugs, and Impaired Driving
1.1 Introduction
Sweden in 1940 (Liljestrand 1940). Seven physicians each examined 100 apprehended driv-
ers and reached a conclusion about alcohol impairment and their fitness to drive. Large dis-
crepancies were noted in percentage of individuals judged as under the influence of alcohol
within the same range of BAC. For example, in the 0.10–0.15 g% range, one of the doctors
considered that 43% of suspects were “under the influence” whereas another concluded that
91% were similarly impaired at this same BAC.
The protocol used to examine traffic offenders gradually became more standardized
for its intended purpose and the conclusions were less dependent on the experience and
training of the examining physicians (Penttila and Tenhu 1976). It was also widely recog-
nized that people reacted differently to the effects of alcohol and some impairment tests
were more sensitive than others in detecting alcohol influence (British Medical Association
1927). Moreover, some people were able to “pull themselves together” in a critical situation,
such as when threatened with criminal prosecution.
The results from clinical tests of drunkenness were, to some extent, influenced by
the suspect’s age, gender, drinking pattern (type of beverage consumed), time after end
of drinking when the examination was made, and the individual’s previous experience
with alcohol consumption (habituation), etc. Other human factors that warranted con-
sideration when traffic crashes were investigated included the driver’s personality, mental
health status, passengers and other distractions (such as children in the vehicle), aspects
of the vehicle itself (brakes, steering, speed), the motoring environment, day or night-time
driving, weather conditions, and so on (Petridou and Moustaki 2000).
If a driver showed signs and symptoms of impairment but there was no smell of alco-
hol on the breath, this raised a warning flag that other drugs might be involved. One of the
tasks of the physician was to rule out a medical condition “simulating” drunkenness, such
as mental instability, a nervous disorder, or metabolic disturbance, such as low blood sugar
(diabetes) or epilepsy, all of which warranted consideration.
The low prevalence of alcohol-positive cases (0.2%) above the legal limit of 0.02 g% con-
firmed the findings from an earlier study done in 2008–2009 (Gjerde et al. 2008).
Detection rates of alcohol-positive drivers depended to some extent on day of week and
time of day when traffic stops were made. The highest prevalence was found in drivers tested
on weekend nights. Other roadside surveys, including mandatory testing of oral fluid speci-
mens, have identified the prevalence of drivers using drugs other than alcohol (Alcaniz et al.
2018). Depending on the country concerned, between 5% and 10% of drivers test positive for
one or more psychoactive substance other than alcohol, in part dependent on weekday and
the time of day (Alcaniz et al. 2018; Gjerde et al. 2013, 2008). Worldwide trends in alcohol
and drug use by drivers were the subject of a 2016 review article, which drew attention to the
need for better standardization of the material collected in different countries and the need
for more research on the role of alcohol and drugs in crashes utilizing a comprehensive pro-
gram of toxicological analysis of biological samples (Christophersen et al. 2016).
The prevalence of alcohol use by drivers in the United States decreased from 1973 to
2014, whereas use of other drugs, both on prescription and illicit substances, increased over
the same time period (Berning et al. 2015). The results from a 2014 national roadside sur-
vey, done on weekdays during daytime, found 1.1% of drivers tested positive for alcohol use
Driving Under the Influence of Psychoactive Substances 7
(BAC > 0.005 g%) and 0.4% were above the 0.08 g% statutory limit. The alcohol-positive
rates for a similar roadside survey done on weekend nights were appreciably higher: 8.3%
positives and 1.5% above the statutory BAC limit (Berning et al. 2015).
In the same US study, the drivers testing positive for non-alcohol drugs (both licit and
illicit) rose to 22.4% in midweek daytime tests and 22.5% positives on weekend nights,
suggesting no statistical difference (Berning et al. 2015). Of the drug-positive cases, roughly
12%–15% involved illegal drugs and 7%–10% of drivers had used prescribed medicines.
The dominant illicit drug was cannabis with a prevalence of 15.2%, followed by prescrip-
tion drugs in 7.3% of the drivers tested on weekend nights. These positive results were
ratified by toxicological analysis of drugs in blood and/or saliva specimens, although the
concentrations of pharmacologically active substances present were not reported.
Further convincing evidence that driving under the influence of alcohol and/or other
drugs is a danger for traffic safety comes from postmortem toxicology results in drivers
killed in crashes. However, making such comparisons between countries is problematic
because different procedures and practices are adopted in selecting crash victims for foren-
sic autopsy and conducting toxicological analysis (Berning and Smither 2014). For example,
in Norway 58% of the drivers killed in crashes included information from drug analysis
(Gjerde et al. 2011), while the corresponding rate was >95% in Sweden (Jones et al. 2009).
Reliable information about drug use by drivers killed in crashes in the United States is
difficult to obtain because there is no consistent policy or procedures about who is actually
tested. Much seems to depend on age and/or gender of the deceased and the jurisdiction
where the crash occurred. Some medical examiners are content with toxicological testing for
ethanol, whereas others require a broad drug-screening analysis. If only 50% of drivers killed
are autopsied, there is nothing known about alcohol and drug use by the remaining 50%.
Furthermore, information is lacking on the scope of the analytical toxicology, such as the
number of drugs tested, the body fluids analyzed, and the analytical cutoff concentrations for
reporting positive results (Berning and Smither 2014). In this connection, it is important to
appreciate that a positive drug finding does not necessarily mean the driver was impaired by
that substance or that the driver was to blame for the road traffic crash (Berghaus et al. 2007).
the notion that alcohol impairment was a causative factor in the crash. Moreover, the mean
autopsy BAC in drivers killed in traffic crashes is often in the 0.15–0.19 g% range, which is
a level associated with gross impairment of driving skills.
The relationship between BAC and diminished performance has been verified in hun-
dreds of experiments using different types of methodology. One approach is the use of
controlled drinking experiments—with healthy volunteers under laboratory conditions,
which usually involve moderate doses of ethanol (Drew et al. 1959). Subjects are required
to perform a battery of cognitive and psychomotor tests before they drink alcohol, to
establish baseline values, and the same tests are administered again at various times
post-dosing (Goldberg 1943). The behavioral test scores are then compared with BAC or
breath-alcohol concentration (BrAC) at the time of testing. Many such laboratory studies
find a strong association between performance decrement (error rates) and BAC, but a
lot also depends on complexity of the task, the time after drinking, and whether testing
was done on the absorptive or postabsorptive limb of the BAC curve (Jongen et al. 2016;
Martin et al. 2013).
Controlled drinking studies in a laboratory environment are unlike real-world conditions,
because the volunteer subjects almost always consume a bolus dose of ethanol in 15–30 min-
utes after an overnight fast (Jones and Neri 1994). Under these conditions, absorption of
ethanol into the blood is fast and initial impairment tends to be more pronounced. Thereafter
a subject’s performance in the behavioral tests rapidly improves and, by 90–120 minutes post
dosing, their test scores are often not significantly different from baseline measurements
before drinking. The general finding from many such studies is that both subjective feelings
of intoxication and objective measures of impairment are more pronounced on the rising
limb of the BAC curve and close to the peak (Jones and Neri 1985, 1994). On reaching the
postabsorptive phase, the volunteer subjects feel tired and sleepy and might perform worse
in behavioral tests for these reasons. Acute tolerance develops to impairment effect during a
single exposure to ethanol; results of cognitive and psychomotor tests 2–3 hours after drink-
ing are not significantly different from pre-drinking scores, despite BAC still being elevated
and above 0.05–0.08 g% (Jones and Neri 1994; Mellanby 1920).
Another methodological approach to establish a relationship between BAC and impair-
ment of driving skills makes use of closed track driving courses. This approach allows for
evaluating complex maneuvers at speed, avoiding traffic cones, and other tasks that require
divided attention, and braking in emergency situations (Bjerver and Goldberg 1950; Laurell
1977). Fairly sophisticated computer-aided tests are available to investigate other skills and
traits associated with driving, such as tracking, divided attention, and simple and choice
reaction times, all of which are relevant for traffic safety (Strand et al. 2016).
In the Netherlands, investigators have developed on-the-road driving tests to mea-
sure impairment from alcohol or other drugs, using specially designed dual-controlled
vehicles with electronic recording of various aspects of the driving. The test subject
is expected to drive on the normal highway in the traffic flow and is required to hold
a steady lateral position and maintain a constant speed (O’Hanlon 1984; Ramaekers
2017; Verster and Roth 2011). The measure of impairment caused by psychoactive sub-
stances is the standard deviation of lateral position (SDLP), which is a quantitative
i ndication of the amount of weaving during the driving task. Studies have shown that
SDLP is a reliable and stable index of driving performance and provides an e asily
u nderstood quantitative measure of weaving with high test-retest reproducibility.
The SDLP shows a significant dose–response relationship to increasing levels of BAC,
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And islands that were the Hesperides
Of all my boyish dreams.
And the burden of that old song,
It murmurs and whispers still:
“A boy’s will is the wind’s will,
And the thoughts of youth are long, long thoughts.”
THE SEA
By Barry Cornwall
RIGHTEOUS WRATH
By Henry Van Dyke
—Outlook.
TO THE SIERRAS
By J. J. Owen
SUNSET
By Ina Coolbrith
SOMETHING TO LOVE
By William Bansman
BROTHERHOOD
By Edwin Markham
MORNING
By Edward Rowland Sill
SLEEP
By Elizabeth Barrett Browning
LABOR
By Frank Soule
Despise not labor! God did not despise
The handicraft which wrought this gorgeous globe,
That crowned its glories with yon jeweled skies,
And clad the earth in nature’s queenly robe.
He dug the first canal—the river’s bed,
Built the first fountain in the gushing spring,
Wove the first carpet for man’s haughty tread,
The warp and woof of his first covering.
He made the pictures painters imitate,
The statuary’s first grand model made,
Taught human intellect to re-create,
And human ingenuity its trade.
Ere great Daguerre had harnessed up the sun,
Apprenticeship at his new art to serve,
A greater artist greater things had done,
The wondrous pictures of the optic nerve.
There is no deed of honest labor born
That is not Godlike; in the toiling limbs
Howe’er the lazy scoff, the brainless scorn,
God labored first; toil likens us to Him.
Ashamed of work! mechanic, with thy tools,
The tree thy ax cut from its native sod,
And turns to useful things—go tell to fools,
Was fashioned in the factory of God.
Go build your ships, go build your lofty dome,
Your granite temple, that through time endures,
Your humble cot, or that proud pile of Rome,
His arm has toiled there in advance of yours.
He made the flowers your learned florists scan,
And crystallized the atoms of each gem,
Ennobled labor in great nature’s plan,
And made it virtue’s brightest diadem.
Whatever thing is worthy to be had,
Is worthy of the toil by which ’tis won,
Just as the grain by which the field is clad
Pays back the warming labor of the sun.
’Tis not profession that ennobles men,
’Tis not the calling that can e’er degrade,
The trowel is as worthy as the pen,
The pen more mighty than the hero’s blade.
The merchant, with his ledger and his wares,
The lawyer with his cases and his books,
The toiling farmer, with his wheat and tares,
The poet by the shaded streams and nooks,
The man, whate’er his work, wherever done,
If intellect and honor guide his hand,
Is peer to him who greatest state has won,
And rich as any Rothschild of the land.
All mere distinctions based upon pretense,
Are merely laughing themes for manly hearts.
The miner’s cradle claims from men of sense
More honor than the youngling Bonaparte’s.
Let fops and fools the sons of toil deride,
On false pretensions brainless dunces live;
Let carpet heroes strut with parlor pride,
Supreme in all that indolence can give,
But be not like them, and pray envy not
These fancy tom-tit burlesques of mankind,
The witless snobs in idleness who rot,
Hermaphrodite ’twixt vanity and mind.
O son of toil, be proud, look up, arise,
And disregard opinion’s hollow test,
A false society’s decrees despise,
He is most worthy who has labored best.
The scepter is less royal than the hoe,
The sword, beneath whose rule whole nations writhe,
And curse the wearer, while they fear the blow,
Is far less noble than the plow and scythe.
There’s more true honor on one tan-browned hand,
Rough with the honest work of busy men,
Than all the soft-skinned punies of the land,
The nice, white-kiddery of upper ten.
Blow bright the forge—the sturdy anvil ring,
It sings the anthem of king Labor’s courts,
And sweeter sounds the clattering hammers bring,
Than half a thousand thumped piano-fortes.
Fair are the ribbons from the rabbet-plane,
As those which grace my lady’s hat or cape,
Nor does the joiner’s honor blush or wane
Beside the lawyer, with his brief and tape.
Pride thee, mechanic, on thine honest trade,
’Tis nobler than the snob’s much vaunted pelf.
Man’s soulless pride his test of worth has made,
But thine is based on that of God himself.