DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING

ACTION RESPONSIBILITY
Generic Name: Interferes with Moderate to severe Hypersensitivity to CNS: headache, Monitor patient for life-
Cefuroxime bacterial cell-wall infections, including cephalosporin or hyperactivity, threatening adverse
synthesis and division those skin, bone, joints, penicillin. hypertonia, seizures effects, including
Brand Name: by binding to cell wall, urinary or respiratory Carnitine deficiency. anaphylaxis, Steven-
Ceftin, Zinacef,ATC, causing cell to die. tract, gynecologic GI: nausea, vomiting, Johnson syndrome, and
Ritemed, Cefurox Active against gram- infections. diarrhea, abdominal pseudomembranaous
negative and gram- pain, dyspepsia, colitis.
Pharmacologic Class: positive bacteria, with pseudomembranous
Second-generation expanded activity colitis Monitor neurologic
cephalosporin against gram-negative status particularly for
bacteria. GU: hematuria, vaginal signs of impending
Therapeutic Class: candidiasis, renal seizures.
Antibacterial dysfunction, acute
renal failure Monitor kidney
Patient’s dose: function test results
500 mg Hematolofic: and intake and output.
haemolytic anemia,
Minimum Dosage: aplastic anemia, Monitor CBC with
125 mg, 1 capsule haemorrhage differential and
prothrombin time:
Maximum Dosage: Hepatic: heptic watch signs and
500 mg, 1 capsule dysfunction symptoms of blood
dycrasias.
Route: Metabolic:
PO, I.V, I.M hyperglycemia Monitor temperature;
watch for signs and
Skin: toxic epidermal symptoms of
necrolysis, erythema superinfection.
multiforme, Steven-
Johnson syndrome
 Other: allergic reaction, Patient teaching:
drug fever,
superinfection, Advise patient to
anaphylaxis immediately report
rash or bleeding
tendency.

Instruct patient to take

drug with
food every 12 hours as
prescribed.

Teach patient how to

recognize signs
and symptoms of
superinfection.
Instruct him to report
these right away.

Advise patient to report

CNS
changes

DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING

ACTION RESPONSIBILITY
Generic Name: Exhibits anti- Ankylosing spondylitis, Hypersensitivity to CNS: dizziness, Monitor CBC,
Celecoxib inflammatory, osteoarthritis drug, sulfonamides, or drowsiness, headache, electrolyte levels,
analgesic, other NSAIDs insomnia, fatigue, stroke creatinine clearance,
Brand Name: and antipyretic action occult fecal blood test,
Celebrex,Ritemed, due to inhibition of Advanced renal disease CV: angina, tachycardia, and liver function test
Emicox, Celcoxx COX-2 enzyme peripheral edema, results every 6 to
Severe hepatic myocardial infarction 12 months.
Pharmacologic Class: impairment
Nonsteroidal EENT: ophthalmic effects, Patient teaching:
cyclooxygenase-2 (COX- Sensitivity precipitated tinnitus,
2) inhibitor, by aspirin epistaxis, pharyngitis, Advise patient to
nonsteroidal anti- rhinitis, sinusitis immediately report
inflammatory drug Third trimester of bloody stools, vomiting
(NSAID) pregnancy GI: nausea, diarrhea, of blood, or signs or
constipation, symptoms of liver
Therapeutic Class: Breastfeeding abdominal pain, damage (nausea,
Antirheumatic dyspepsia, flatulence, fatigue, lethargy,
dry mouth, GI bleeding pruritus, yellowing of
Patient’s dose: eyes or skin, tenderness
200 mg, 1 capsule GU: menorrhagia, renal in upper right abdomen,
failure or flulike
Minimum Dosage: symptom).
50 mg, 1 capsule Hematologic:
eosinophilia, ecchymosis, Instruct patient to take
Maximum Dosage: neutropenia, leukopenia, drug with food or milk.
400 mg, 1 capsule pancytopenia, Tell patient to avoid
thrombocytopenia, aspirin and
Route: agranulocytosis, other NSAIDs (such as
PO granulocytopenia, aplastic ibuprofen and
anemia, bone marrow naproxen) during
depression therapy.

Hepatic: hepatotoxicity As appropriate, review

 all other significant and
Metabolic: life-threatening adverse
hyperchloremia, reactions and
hypophosphatemia interactions, especially
those related to the
Musculoskeletal: back drugs, tests, herbs,
pain, leg cramps behaviors mentioned
above.
Respiratory: upper
respiratory tract
Infection

Skin: rash

Other: anaphylaxis

DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING

ACTION RESPONSIBILITY
Generic Name: Water-soluble vitamin Recommended dietary Prolonged use of CNS: dizziness, Monitor blood pressure
Ascorbic Acid with antioxidant allowance excessive doses headache to evaluate drug
properties; stimulates contraindicated in efficacy.
Brand Name: collagen diabetes mellitus, GI: diarrhea, nausea,
Ritemed, Bewell-C, formation and sodium-restricted diet, vomiting, heartburn Monitor urine output.
TGP, C-supreme, enhances tissue repair concurrent
Ultima-C, Vita-C, Cecon, anticoagulant use, and Assess liver and kidney
Cevi-Bid, Dull-C history of recurrent function tests and
renal calculi electrolyte levels.
Patient’s dose:
500 mg OD Remind the patient
Use cautiously in about yellow urine
 hypersensitivity to (urochrome) due taking
Minimum Dosage: tartrazine or sulfites (if ascorbic acid.
25 mg, 1 capsule product contains these
compounds), before
Maximum Dosage: tests
1500 mg, 1 capsule for occult blood in
stool, and in
Route: breastfeeding patients.
PO, I.V, I.M
Don’t exceed
recommended amount
in pregnant patients.