NAPLEX Practice Questions

Weight & CrCl Calculations-Student

1. Calculate the ideal body weight, in kilograms, for a female patient weighing 60 kg and measuring
160 cm in height.

2. Calculate the BMI for a male who is 6” tall and weighs 198 lb. Round to the nearest tenth. Is the
patient underweight, normal weight, overweight, or obese? Round to the nearest tenth.
(RxPrep)

3. Patient profile: 72-year-old female, 5’5” and 198 lbs.

a. Is the patient underweight, normal weight, overweight, or obese?
b. What weight you will use to calculate:
i. UFH dose?
ii. Theophylline dose?
iii. Aminoglycoside dose?

4. A female patient is to receive 5 mg/kg/day of theophylline. The patient is 5’7” and weighs 243
pounds. Calculate the daily theophylline dose the patient should receive. (RxPrep)

5. A 34-year-old male (height 6’7”, weight 287 pounds) is hospitalized after a motor vehicle
accident. He develops a Pseudomonas Aeruginosa infection. The physician orders tobromycin 2
mg/kg IV q 8hr. Calculate the tobromycin dose. Round to the nearest 10 milligrams. (RxPrep)

6. Levofloxacin, dosing per pharmacy, is ordered for an 87 years old female patient (ht 5’4”, weight
103 lb). her labs include BUN 22 mg/dL and SCr 1 mg/dL. Choose the correct dosing regimen
based on the renal dosing adjustments from the package labeling below: (RxPrep)

CrCl ≥ 50 mL/min 20-49 mL/min <20 mL/min

Levofloxacin Dose 500 mg q24 hr 250 mg q24 hr 250 mg q48 hr

7. A 70-year-old gentleman and his 68-year-old wife have their annual physical exams. He weighs
160 lb and she 126 lb. His blood work reveals a serum creatinine of 1.3 mg/dL and hers is 1.1
mg/dL. Using the Cockcroft-Gault equation, calculate wife’s creatinine Clearance Rate. Round to
the nearest tenth.

8. The pharmacist reviews the order for IV Bactrim the labs for Mr. Ross in the profile. What does
should Mr. Ross receive given the renal dosage recommendations below? (RxPrep)

CrCl ≥ 30 mL/min 15-30 mL/min <15 mL/min

Bactrim Dose No dose adjustment Administer 50% of the recommended dose Use is not recommended
NAPLEX Practice Questions
Weight & CrCl Calculations-Student

Patient Profile
Age 41 sex M Race Caucasian height 6’1” weight 70 kg
Allergies NKDA

MEDICATIONS:
12/10/2021 Celexa 20 mg 1 tablet daily
12/10/2021 Lipitor 10 mg 1 tablet daily
04/20/2022 Bactrim 20 mg TMP/kg/day IV divided q6h

LAB TESTS:
Test Normal Value 04/20/2022 12/10/2021
Na 135-146 mEq/L 139 142
K 3.5-5.3 mEq/L 3.7 4.1
WBC 4000-11,000 cells/m3 10.7 9.5
BUN 7-25 mg/dL 7 9
SCr 0.6-1.2 mg/dL 0.6 0.8

a. 1400 mg TMP IV q6h

b. 700 mg TMP IV q6h
c. 400 mg TMP IV q12h
d. 350 mg TMP IV q6h
e. Mr. Ross should not receive Bactrim

9. How many grams of aminophylline will Mike receive per day based on the order in the profile?
Round to the nearest 1 g. (RxPrep)

Patient Profile
Age 22 sex M Race Caucasian
Allergies NKDA

MEDICATIONS:
02/23/2022 Methylprednisolone 40 mg IV q12hr
02/23/2022 Qvar 1 puff (40 mcg) BID
04/25/2022 Aminophylline 0.5 mg/kg/hr

LAB TESTS:
Test Normal Value 02/23/2022 04/25/2022
Weight 141 160
Height 5’9” 5’9”
WBC 4000-11,000 cells/m3 12,000 11225
NAPLEX Practice Questions
Weight & CrCl Calculations-Student

10. A patient lab report shows that BUN = 54 mg/dL, Creatinine = 1.8 mg/dL. Is the patient hydrated
or dehydrated?
BUN Reference Range: 7-25 mg/dL
SCr Reference Range: 0.6 – 1.2 mg/mL

11. Nancy is receiving a furosemide infusion at 5 mg/hr. The nurse notices her urine output has
decreased in the last hour. Laboratory values are drawn and the patient has a SCr of 1.5 mg/dL
and a BUN of 26 mg/dL. The nurse wants to know if she should stop the furosemide infusion due
to the patient becoming dehydrated. What is the correct assessment of the patient’s hydration
status?
a. The patient appears to be too hydrated given the laborites results
b. The patient is not experiencing dehydration
c. The patient is experiencing dehydration and may need to be started on fluid
d. The patient has subjective information indicating dehydration but the patient needs to
be assessed objectively as well.
e. None of the above are correct

Heparin and Low Molecular Weight Heparin Dosing:

12. A 198-lb hospitalized patient is placed on heparin therapy to treat a pulmonary embolism. The
patient requires a bolus injection followed by a heparin infusion. The hospital follows the
protocol shown in Figure 1. The hospital pharmacist has heparin available for bolus doses
containing 5000 units/mL in 5-mL vials and heparin for intravenous infusion in 250-mL infusion
bags each containing 25,000 units of heparin.
a. How many milliliters of the 5000 units/mL injection should the pharmacist recommend
as a bolus dose? Round to 1 decimal place.
b. How many milliliters per hour of the heparin infusion should the pharmacist instruct the
nurse to deliver, based on the standard infusion protocol? Round to 1 decimal place.
c. If the intravenous set is programmed to deliver 60 drops per milliliter, what should be
the flow rate, in drops per minute, to deliver the mL/h required in answer (b)? Round to
a whole number.
d. How long will the 250-mL infusion bag last, in hours?

13. A male patient weighing 76 kg is placed on heparin therapy for the prevention of deep vein
thrombosis after surgery.
a. How many milliliters of a heparin injection containing 5000 units/mL should be
administered for a loading dose of 80 units/kg? Round to 1 decimal place.
b. What should be the infusion rate, in mL/h, using a solution that contains heparin 25,000
units/500 mL, to administer 18 units/kg/h? round to two decimal places
NAPLEX Practice Questions
Weight & CrCl Calculations-Student

c. Six hours after heparin therapy is initiated, the patient's aPTT is found to be 75 seconds.
Adjust the infusion rate, in mL/h, according to the heparin protocol (Fig. 1). Round to
two decimal places.

14. Heparin sodium may be administered to children by intermittent intravenous infusion every 4
hours at doses ranging from 50 to 100 units/kg of body weight. Using an injection containing
heparin, 5000 units/mL, calculate the daily dosage range, in milliliters, for a 50-lb child.

15. A patient takes the maximal daily dose of phentermine/topiramate for the treatment of obesity.
The patient’s baseline BMI is 36 kg/m2 and weight is 115.7 kg (255 lb). Which best represents
the minimum weight loss required to consider continuing treatment with this agent after 3
months of therapy? A. 3.2 kg (7 lb). B. 5.9 kg (13 lb). C. 7.7 kg (17 lb). D. 11.8 kg (26 lb).

16. B.D. is a 73-year-old male (height 175 cm, weight 80 kg) with newly diagnosed NVAF. He also has
a history of hypertension, dyslipidemia, stable ischemic heart disease, and systolic heart failure.
His medications include aspirin 81 mg orally daily, enalapril 10 mg orally daily, metoprolol
succinate 200 mg orally daily, furosemide 40 mg orally daily, spironolactone 25 mg orally daily.
His heart rate is 72 beats/minute and blood pressure is 122/72 mm Hg. His laboratory values
include K 4.9 mEq/L, stable SCr 1.9 mg/dL, and blood glucose 101 mg/dL. According to this
patient’s CHA2 DS2 -VASc score this patient should be on DOAC therapy for reducing the risk of
stroke. Which is the most appropriate Dabigatran regimen for reducing B.D.’s risk of stroke?

CrCl >30 mL/min 15-30 mL/min <15 mL/min

Dabigatran 150 mg BID 75 mg BID Contraindicated

IBW= 70.44  Use IBW

Crcl= 34.49 between 30 and 50 so Dabigatran 150 mg BID
When CrCl < 30  Dabigatran 75 mg BID

17. A patient (weight 75 kg) is to be initiated on a continuous infusion of norepinephrine for blood
pressure support because of septic shock. The nurse has a 250-mL bag of normal saline
containing 4 mg of norepinephrine. Which rate is most appropriate to infuse the norepinephrine
drip at a dose of 0.05 mcg/kg/minute? A. 7 mL/hour. B. 14 mL/hour. C. 31.5 mL/hour. D. 79
mL/hour.