SIGNAL TO NOISE REPORT

A C Q U I S I TI O N I N F O R M A TI O N

System Name: e2695_2489 MSG

Project Path: RC2_SQT _e2695_2489 final
Processing Method: 100 Signal to Noise PM
Sample Kit Expiration Date: Friday, August 16, 2019 12:00:00 AM EDT
Sample Kit Lot Number: W16081621
Report Method: 100 Signal to Noise RM Acquired By: Melissa
Sample Set Name: Signal to Noise SSM Column Serial Number: 01833630013817
Sample Set Id: 6813 Result Set Id: 6820

To define the sensitivity of the detector, it is necessary to determine that for a known concentration and condition,
a peak can be unambiguously distingushed from noise when eluted from the column.

In the signal to noise test, the peak height is divided by peak to peak noise and the test passes if the signal to
noise > 6000.

Results are rounded to the same precision as displayed by the acceptance criterion prior to comparing against the
specification.

Signal to Noise Results

Signal to Noise Signal to Noise
Signal to Noise
Spec Pass/Fail
1 > 6000 93115 PASS

Waters Project Name and Version: SQT_E_2695_2489 v4.00 © 2017 Waters Corporation. All rights reserved.
Date: Monday, February 20, 2017
Printed: 11:21:31 AM US/Eastern Page: 1 of 2
 SIGNAL TO NOISE REPORT

A C Q U I S I TI O N I N F O R M A TI O N

System Name: e2695_2489 MSG Sample Set Id: 6813

Project Path: RC2_SQT_e2695_2489 final Result Set Id: 6820

Signal to Noise Chromatogram

0.40

0.30
AU

0.20
Caffeine - 1.216

0.10

0.00

1.00 1.50 2.00 2.50 3.00 3.50 4.00 4.50 5.00 5.50 6.00
Minutes

Signal to Noise Peak Results

Retention
Inj ection Inj ection Volume Height Peak to Peak Noise
Sample Name Vial Name Time Result Id
Number (µL) (µV) (Plot Units)
(min)
1 Caffeine 0.06 mg/mL 74 1 10.00 Caffeine 1.22 418782.00 0.000004 6824

Signal to Noise
Summary
Results
Signal to Noise
1 93115

Waters Project Name and Version: SQT_E_2695_2489 v4.00 © 2017 Waters Corporation. All rights reserved.
Date: Monday, February 20, 2017
Printed: 11:21:31 AM US/Eastern Page: 2 of 2