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Nursing Study Guide - Causes of Disease - Wikibooks, Open Books For An Open World
Nursing Study Guide - Causes of Disease - Wikibooks, Open Books For An Open World
Nursing Study Guide - Causes of Disease - Wikibooks, Open Books For An Open World
Guide/Causes of
disease
< Nursing Study Guide
Health is a state of physical and mental wellbeing in which the body is able to function fully,
with comfort and with the ability to renew and restore itself. On the other hand, disease is any
departure from health; it is any disorder of a body system that interferes with the normal
operation of a body process. For the purposes of this manual, disease (or sickness) will be
defined as any departure from health that is caused by pathogenic organisms or any other
factor not involving an external physical force; injury (wound) will be defined as any departure
from health due to an external physical force or environmental condition.
Classification of
Disease
Causes
The following broad groupings are recognized causes of disease
Predisposing Causes
These are factors that increase the probability of an individual becoming ill.
Classification of Injuries
Injuries and wounds are classified by type, location, and causative agent. The extent of injury
is described as severe, moderate, slight, superficial (involving surface tissue only), or deep
(involving tissues below the subcutaneous layer). When there is no break in the continuity of
the skin or mucous membrane, the injury is referred to as a closed wound. When the skin or
mucous membrane is cut or penetrated, the injury is referred to as an open wound.
Classification by Type
Classification by Location
Wounds are classified according to anatomical parts of the body as head wounds (these are
subdivided into skull, face, and jaw wounds); chest wounds; abdominal wounds; wounds of
the extremities (arms or legs); wounds of joints; and spinal and pelvic wounds. The part of
the body most severely injured determines the primary classification of multiple wounds.
Classification by Causative Agent
The agent responsible is especially important in diagnosis and treatment because of some
known factors in the type of tissue damage that results from different causative agents.
Pathogenic organisms
affecting disease and
injury
Microorganisms
All things that exist in nature are classified into three general groups—animal, vegetable, and
mineral. The animal and vegetable groups are living and are therefore classed as organisms
(any living thing). Living plants and animals too small to be seen singly except with the aid of
a microscope are microorganisms. Varying in size, shape, and their effect on man, they
become visible to the naked eye only when they form colonies or groups.
Classification.
Microorganisms belonging to the animal kingdom are called protozoa ; those belonging to
the vegetable group are the bacteria, fungi (yeasts and molds), the rickettsia, the spirochetes,
and the viruses. Protozoa cause such diseases as malaria and amoebic dysentery. Most
infectious diseases of man are caused by bacteria or viruses.
Prevalence.
Microorganisms are found almost everywhere ; in the air, on uniforms, on the hands, on the
furniture, on the feet, on flies and other insects, and on the floor. They are even taken into the
body with every breath and with every mouthful of food. Fortunately, many of these are
nonpathogenic (not harmful) to man. Moreover, natural body defenses protect to a certain
extent against the harmful ones. As microorganisms are constantly present even in the air
itself, complete absence of microorganisms on items commonly used is impossible. The
goal is to have as few microorganisms present as possible by using all known preventive
measures against infection and disease.
Destruction
There are many methods of destroying microorganisms, but some are more effective than
others. Washing with soap and water or exposure to light, fresh air, heat, and chemicals are
effective only with some microorganisms, not all. The only known methods that assure
complete destruction of microorganisms are steam under pressure (autoclaving, the
procedure used by most hospitals), burning (flaming or actual burning), and exposure to a
gas such as ethylene oxide. These three methods destroy even resistant spores
(microorganisms encased in a hard outer shell) and leave an article sterile (absolutely free of
all microorganisms).
Classification of Pathogenic
Organisms
Classification of Bacteria
The identification of bacteria under the microscope helps to confirm the diagnosis of many
infectious diseases. Bacteria can be classified and described in terms of shape, oxygen
requirements, ability to cause disease, and ability to form spores.
Classification by Shape. Significant
bacteria can be divided by their shape
into three main groups. These groups
are the cocci, round or ballshaped
bacteria; the bacilli, slender rod-shaped
bacteria; and the spirochetes,
corkscrew-shaped bacteria.
Cocci. The cocci are characterized by
formation of pus (pyogenic bacteria).
Primary members of this group are
staphylococci, streptococci, and
diplococci.
Staphylococci group themselves in
grapelike clusters. They form thick,
yellow or white pus. They cause most
boils, pyogenic infections of the fingers
and hands, and "stitch abscesses" in
surgical wounds. they can always be
found on the normal skin and almost
always in the nasal passages.
Streptococci arrange themselves in
chains or beadlike formations. They
form a thin, watery pus. Streptococci
cause a type of infection that tends to
spread within body tissues to a greater
extent than infections caused by
staphylococci. Common in the mouth
and throat, they cause systemic
disease such as scarlet fever, as well
as extremely serious wound infections.
Diplococci arrange themselves in
pairs. They cause such infections as
gonorrhea and meningococci
meningitis.
Bacilli. Bacilli are characterized by
variations in their rod shape from
straight to irregular curved and
branched shapes. Some bacilli form
spores within themselves which may
alter their appearance to a bottle or
drumstick shape.
Escherichia coli belong to a group of
true rod-shaped bacilli which normally
live in the human intestinal tract. This
bacillus is found in the intestinal tract
and on the skin of the perineal area.
When introduced into wounds, it
produces infection characterized by
light brown pus with a fecal odor.
Clostridium tetani belong to the
rodshaped spore formers that appear
drumstick shaped while they contain
the spores. The spore of Clostridium
tetani finds conditions favorable for
changing back to its original form
when introduced into wounds. Tetanus
(lockjafa) is caused either by the
introduction of Clostridium tetani or by
the introduction of its spores.
Corynebacterium diphtheria are usually
short, thick rods in palisade (picket
fence) arrangement. They cause
diphtheria and are spread by nasal or
oral droplets from infected persons, as
well as by direct contact
Spirochetes. The spirochetes are
characterized by their corkscrew shape
and their ability to move or twist.
Treponema pallidum causes syphillis, a
communicable disease, usually
venereal. The source of infection is
contact with lesions of the infected
person or, rarely, with moist infected
body secretions.
Classification by Oxygen
Requirements
Bacteria are divided into two classes, depending on their ability to live in the presence of free
oxygen.
Distribution of Bacteria
Body Reactions to
disease and injury
Inflammation
Inflammation is the local reaction of the body to irritation or injury. It occurs in tissue that is
injured but not destroyed. It is a defensive and protective effort by the body to isolate and
eliminate the injuring agent and to repair the injury. A certain degree of inflammation takes
place following any type of injury, including a wound made under aseptic conditions by a
surgeon.
Healing
Healing is a process related to inflammation, for both are started by tissue injury. It would be
ideal if the body could heal itself by replacing all damaged tissues with an exact counterpart;
then, an eye would be replaced with a new eye and a tooth with a new tooth. But very few
tissues are replaced in kind. Examples of tissues which may replace themselves are liver
tissue, kidney tubules, and connective tissue. Bone — which is one kind of connective tissue
— may replace itself if broken; that is, the broken bone is repaired by the formation of new
bony tissue. Healing in most tissues is, however, a process of replacement ; the destroyed
tissue is replaced by scar tissue (fibrous type of connective tissue). If brain cells are
destroyed, they are replaced by connective tissue. If the heart muscle is injured, the damaged
fibers are replaced by connective tissue. When a tooth is pulled or an eye is lost, the sockets
are filled with connective tissue. Hence, replacement by scar tissue is the usual order in
healing. The healing process tak6s place in one of two ways — by primary union or by
granulation.
Infections
&General. Infection is the entry and development or multiplication of an infectious agent in
the body. The agent can be any pathogenic organism. Factors that contribute to the ability of
the infectious agent to produce infectious disease include the number and kind of invading
organisms, the ability of the body to resist infection, and the virulence of the infecting
organisms. Virulence is the ability of pathogenic organisms to overcome, at least temporarily,
the defensive reactions of the body (phagocytosis, immunity, and lymphatic involvement)
which are all mobilized when infection occurs. Virulent organisms have the ability to multiply
rapidly within body tissues and to form toxins (poisonous waste products). Pathogenic
organisms produce different kinds of toxins; some toxins destroy tissue cells, some dissolve
blood cells (hemolysis), and some are absorbed rapidly into the blood to cause toxemia, a
generalized systemic reaction to infection. ====Acute Local Injection====
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