5/10/24, 10:48 AM NSF/ANSI 455-2: The Gold Standard for Dietary Supplement GMP… | NSF

Knowledge Library

NSF/ANSI 455-2: The Gold Standard for

Dietary Supplement GMP Certification
NSF/ANSI 455-2 GMP Certification for dietary supplements is essential for products and
brands to compete in the digital and physical marketplace.

In the competitive dietary supplement manufacturing world, ensuring the final product’s
safety and quality is paramount, and that process begins with Good Manufacturing
Practices (GMP) certification. GMP certification is a gold standard for manufacturers,
indicating that they adhere to strict quality control measures and follow industry best
practices. This article delves into the importance of GMP certification for dietary
supplement companies, specifically focusing on the NSF/ANSI 455-2 certification.

The importance of GMP certification for dietary

supplement companies
For several reasons, NSF/ANSI 455-2 GMP certification is vital for dietary supplement
companies. Firstly, it helps ensure that their products meet the highest quality and safety
standards. NSF facilitated the development of the NSF/ANSI 455-2 GMP standard for
dietary supplements and manages the ongoing joint committee dedicated to keeping the Privacy - Terms

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standard vital and current. The NSF/ANSI 455-2 joint committee comprises representatives
from regulatory, industry, and standards development, working together to advance public
safety in the industry.
NSF/ANSI 455-2 standard GMP-certified companies follow rigorous protocols in every
manufacturing process, from sourcing raw materials to packaging the final product. This
significantly reduces the risk of contamination, cross-contamination, and other
manufacturing errors that could compromise the integrity of the dietary supplements.
Secondly, NSF/ANSI 455-2 GMP certification improves the credibility and reputation of
dietary supplement companies. When consumers see the NSF/ANSI 455-2 GMP
certification mark, they can trust that a company’s facility has undergone thorough auditing
and meets stringent quality standards. This trust is crucial in an industry where there have
been instances of adulterated or contaminated products. NSF/ANSI 455-2 GMP
certification helps companies differentiate themselves from unscrupulous competitors and
build a loyal customer base.
Lastly, NSF/ANSI 455-2 GMP certification is often a requirement to enter specific markets
or work with reputable retailers. Physical and digital retailers often demand NSF/ANSI 455-2
GMP certification as a prerequisite for stocking products on their shelves. By obtaining
NSF/ANSI 455-2 GMP certification, dietary supplement companies can expand their market
reach and gain access to lucrative distribution channels.

Overview of NSF/ANSI 455–2 GMP certification

NSF/ANSI 455-2 GMP certification is among the industry’s most recognized and respected.
NSF is an independent, global organization that creates standards for various industries,
including dietary supplements. NSF/ANSI 455-2 GMP certification signifies that a company
has met the stringent requirements outlined in the NSF/ANSI 455-2 standard for dietary
supplements.
NSF/ANSI 455-2 GMP certification offers numerous benefits for dietary supplement
companies. Firstly, it demonstrates a commitment to quality and safety, which can enhance
the company’s reputation and attract discerning customers. The certification process
scrutinizes the manufacturing process through comprehensive audits and inspections.
NSF/ANSI 455-2 GMP certification also provides a competitive advantage in the
marketplace. With the growing demand for dietary supplements, consumers are becoming
increasingly discerning about the products they purchase. By displaying the NSF GMP
certification seal, companies can assure consumers that their products are manufactured to
the highest standards. This recognized certification can result in increased sales and
customer loyalty.
Furthermore, NSF/ANSI 455-2 GMP certification can streamline operations and improve
efficiency. The certification process requires companies to establish robust quality
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management systems, standard operating procedures, and documentation practices. These

systems help companies identify and address potential issues before they escalate, reducing
the risk of costly recalls and product failures.

Understanding the NSF/ANSI 455–2 GMP

standard for dietary supplements
NSF GMP certification centers on the NSF/ANSI 455-2 standard for dietary supplements.
This standard outlines the specific requirements that manufacturers must meet to ensure
their manufacturing process’s quality, safety, and efficacy. Some critical elements of the
NSF/ANSI 455-2 standard include:
Manufacturing controls: Manufacturers must have robust systems to control critical
aspects of the manufacturing process, such as formulation, mixing, and packaging.
Facility and equipment maintenance: Manufacturers must maintain their facilities and
equipment to keep them clean and hygienic to prevent cross-contamination and ensure
product integrity.

The process of obtaining NSF GMP certification

Obtaining NSF/ANSI 45-2 GMP certification is a transformative quality process for
companies. First, the company must conduct a thorough self-assessment to identify gaps in
its manufacturing processes. Once the company addresses these gaps, it should proceed
with the certification application.
The next step is the on-site audit, where NSF auditors visit the company’s facilities to
assess compliance with the NSF/ANSI 455-2 standard. During the audit, the auditors review
documentation, observe manufacturing processes, and interview key personnel. Any non-
compliance issues are identified and must be resolved before certification is granted.
After completing a successful audit, the company wil be awarded the NSF/ANSI 455-2
GMP certification. However, just as quality should be an ongoing process, the certification is
not a one-time achievement. To maintain the certification, companies must undergo regular
surveil ance audits to ensure ongoing compliance with the standard.

Choosing the right GMP certification for your

dietary supplement company
Dietary supplement companies should consider their target market, customer preferences,
and brand values when deciding which certifications to pursue. NSF/ANSI 455-2 GMP
certification is an excellent starting point, as it covers the essential aspects of quality and
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safety. And NSF/ANSI 455-2 certification is the foundation of reputational quality, and the
first step toward additional certifications, including product certifications such as NSF/ANSI
173 Contents Certified and NSF 306 Certified for Sport®. NSF/ANSI 455-2 puts companies
on their way to product certification, differentiating products further and aligning with
specific consumer demands.

The impact of NSF/ANSI 455–2 GMP certification

on consumer trust and sales
Consumers increasingly seek assurance that their products are safe in a market saturated
with dietary supplement options. In a recent independent survey, 82 percent of consumers
wanted retailers to scrutinize the supplements’ manufacturing facilities, emphasizing the
importance of quality control. This high percentage signals a growing awareness among
consumers regarding the need for transparency and accountability in the manufacturing
process.
Download a copy of the survey here.
Consumers also indicated NSF/ANSI 455-2 GMP certification significantly impacts their trust
in a product. The NSF/ANSI 455-2 GMP certification mark provides this assurance, giving
consumers confidence in their purchase decisions.
Moreover, NSF/ANSI 455-2 GMP certification can increase sales and market share.
Consumers are likelier to choose brands that promote the NSF/ANSI 455-2 GMP
certification mark, as it signifies a commitment to quality and safety. By investing in
NSF/ANSI 455-2 GMP certification, dietary supplement companies can gain a competitive
edge and capture a larger market share.

Investing in NSF/ANSI 455–2 GMP certification for

long-term success
In conclusion, NSF/ANSI 455-2 GMP certification is vital for dietary supplement companies
aiming to establish themselves as industry leaders. The certification demonstrates a
commitment to quality, safety, and transparency, which enhance a company’s reputation and
attract discerning customers. Companies can ensure their manufacturing processes meet the
highest industry standards by adhering to the stringent requirements outlined in the
NSF/ANSI 455-2 standard.
Investing in NSF/ANSI 455-2 GMP certification is an investment in long-term success. It
improves consumer trust, supports higher sales, and helps companies streamline operations
and mitigate risks. By obtaining NSF/ANSI 455-2 GMP certification, dietary supplement
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companies can position themselves as leaders in the industry and pave the way for future
growth.

Ready to take your dietary supplement

company to the next level?
Get your company certified with NSF/ANSI 455-2 GMP certification today!
Contact us

Would you like to learn more about GMP certification

NSF provides GMP registration and NSF/ANSI 455 certification for dietary supplements,
cosmetics, personal care products and OTC drugs.

Learn more

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