Certificate of Analysis

Product Name: Glibenclamide

Catalog Number: M3547
CAS Number: 10238-21-8

Physical and Chemical Properties

Formula: C23H28ClN3O5S
Molecular Weight: 494
Solubility: DMSO > 100 mg/mL
Powder -20°C 3 years ; 4°C 2 years
Storage:
In solvent -80°C 6 months ; -20°C 1 month

Chemical Structure:

Analytical Data

QC Standard: 99.92%
H-NMR: Consistent with structure

Product Information

Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor.

Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1
Description:
subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator
protein (CFTR).

Stability and Solubility Advice:
Information concerning product stability, particularly in solution, has rarely been reported and
in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed
vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for
some special products should refer to their storage details.

AbMole BioScience *Products are for research use only.