Foundation

Block

Connective
Tissue

Color Index:
-Main Text -Important -Notes
Editing File
-Boy Slides -Girl Slides -Extra
Objectives:

01 Enumerate the general characteristics

of C.T. 04 Classify C.T.P.

02 Classify C.T. into C.T. proper (C.T.P.) and Describe the structure, distribution, and
special types of C.T. 05 function of different types of C.T.P.

03 Describe components of C.T.P.

06 Enumerate the functions of C.T.
Definition of C.T.
● It is one of the 4 basic tissues.
● It is mesodermal in origin.
● It supports, binds, and connects other tissues and organs
providing structural and metabolic support for them.

General Characteristics of C.T.

● C.T. is formed of widely separated, few cells with abundant
extracellular matrix.
● Most C.T. are vascular(has blood vessels)
 cells (of C.T.P.)

Unilocular Multilocular Leucocytes

Fibroblast Macrophages Mast cells Plasma cells adipose cells Adipose Cells
Name

( white blood cells)

(Adipocytes, fat cells)

-Most common cell; -appear normally in

found nearly in all C.T. proper.
types of C.T. proper. -basophilic cytoplasm -Small cells with
-Basophilic cytoplasm with a negative Golgi -Large, spherical, with multiple smaller lipid -Neutrophils increase
-Flat branched cells rich in lysosomes. image. a single large fat droplets. in acute inflammation.
L/M

(spindle-shaped) with droplet.

basophilic cytoplasm -Irregular outlines. -Cytoplasm contains -Nucleus: spherical, -Nucleus: spherical, -Lymphocytes and
(full of ribosomes). numerous basophilic eccentric with a -Thin rim of cytoplasm not flattened. monocytes increase in
-They can divide. cytoplasmic granules. clock-face appearance at the periphery. chronic inflammation.
-They can divide. of chromatin.
-They originate from -Nucleus: flattened, “Med 443” -Eosinophils and
-Old fibroblasts are blood monocytes. -Derived from peripheral. basophils increase in
called fibrocyte. B-lymphocytes. allergic inflammation.
(blast > Active)
(cyte > Less Active) “Important”
Function

Types of Leucocyte
-Formation of proteins
of C.T. fibres. -Secrete heparin Production of body
(anticoagulant) heat because of their
-Formation of C.T. (helps prevent blood clots) Secretion of antibodies Synthesis, storage and large number of
Phagocytosis
matrix. (immunoglobulins) release of fat. mitochondria.
-Secrete histamine
-Healing of wounds (allergic reaction). “Med 443”
(cell divide)
 Note: other important types of
Collagen includes:

Fibers -Type II (in cartilage)

-Type IV (in basement membranes)

Collagen Fibers Reticular Fibers Elastic Fibers

● Made of
● Made of collagen
collagen type I ● Made of Elastin
type III
● Non-Branched, ● Branched
● Branched and
arranged in
form a network
bundles ● Stained Brown
● Stained Black with orcein
● Acidophilic (Reddish-brown dye)
with silver
 Connective Tissue proper (According to the most predominant element)
1- Loose(Areolar) C.T. 2- Dense collagenous 5- Unilocular adipose
C.T. 3- Elastic C.T. 4- Reticular C.T. tissue
Type

(Most common C.T.P.) (White Adipose Tissue)

-Contains all the main

components of C.T.P.:
All types of C.T. cells and -Predominance of -Predominance of -Predominance of
L/M

-Predominance of
fibers + abundant matrix. elastic fibers (sheets or reticular fibers + reticular Unilocular fat cells.
collagen fibers + fibroblasts.
membrane) + fibroblasts. cells (specialized fibroblasts)
-No predominant element
in loose C.T.

-Subcutaneous tissue
1-Dense regular:
especially in :
e.g. tendons, ligaments -Stroma of organs:
Sites

-E.g. Subcutaneous tissue .Buttocks

E.g. liver, lymph node,
-Large arteries: E.g. Aorta. .Abdominal wall
2-Dense irregular: spleen.
( the layer of tissue underlines .Female breast
e.g. dermis of the skin,
the skin)
capsules.
-Around the kidney
Function

1- Synthesis, storage,
release of fat.
Tough tissue; resistance to
Elastic tissue; Stretchable Structural support 2- Supports organs e,g.
stretch
Kidney
3- Heat insulation
Functions of Connective Tissue proper
1-Supports, binds and connects other tissues and organs.

2- Nourishes the surrounding structures, through its blood

vessels.

3- Its Cells provides Healing of injured tissues, Produce

heparin, histamine and antibodies, Store fat, preserve body
temperature and Protect against microorganisms.

4- Its Fibers provide rigidity or elasticity

MCQs
1-What is the most common cell in C.T. proper ?

A- Plasma cells B- Macrophages C- Fibroblast D- Mast cells

2- What type of cells is rich in lysosomes ?

A- Reticulocytes B- Mast cell C- Fibroblast D- Macrophages

3- Which of the following structures are the main component of dense collagenous C.T. ?

A-Reticular fibers B- Collagen fibers C- Collagen fibers D- Elastic fibers

only and fibroblast
MCQs
4-Which of the following cells is responsible for phagocytosis ?

A- Macrophages B- Mast cells C- Fat cells D- Fibroblasts

5- Which of the following connective tissues consists of type III collagen?

A- Reticular B- Adipose C- Dense D- Elastic

collagenous
6- Which of the following cells is responsible for the secretion of antibodies?

A-Fat cells B- Fibroblast C- Mast cells D- Plasma cells

1-C 2-D 3-C 4-A 5-A 6-D

 The Team
Team Leaders:
● Ahmad Addas ● Hessah Alghanim

Team Members:

● Saud Alsaeed ● Joud Alahmari

● Fahad Alqahtani ● Lulwah Alwabel
● Abdulaziz Alobathani ● Hessah Alyousef
● Ibrahim Albabtain ● Haneen Baatiah
● Fahad Albalawi ● Norah Alnoshan
● Faisal Alessa ● Lina Albaqiyh
● Yazan Alkheder ● Layan Alsubaie
● Ziyad Bukhari ● Ghaida Alotaibi
histology.444ksu@gmail.com