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g9 Endocrine System WR
g9 Endocrine System WR
THE ENDOCRINE
SYSTEM
PRESENTED BY:
ESTRADA, GENICA B.
GONZALES, DONALD L.
BINALLA, REGIN T.
PRADO, JONARD P.
PRESENTED TO:
MRS. NORA CONDING
NAME: ESTRADA, GENICA B.
ENDOCRINE GLANDS - Are glands that release their produced substance directly into the
blood stream. Endocrine glands are part of the endocrine system, which is a system of
structures within the body that work together to monitor, produce, and secrete hormones
throughout the body. Endocrine glands do not
use ducts to release their products.
PINEAL GLAND
PITUITARY GLAND
This is a small, pea-sized gland at the base of your brain below your hypothalamus.
THYROID GLAND
PARATHYROID GLAND
ADRENAL GLAND
EXOCRINE GLAND:
These glands create a wide variety
of products and excrete them
through a network or ducts. The
products that are created in the exocrine glands are released to the outside environment (such
as on the skin or in the mouth) and not into the blood stream.
ENDOCRINE SYSTEM ORGANS - Certain organs in your body also make and release
hormones. An organ is a group of tissues that form a structure that performs specific
important functions in your body. The organs that are part of your endocrine system include:
HYPOTHALAMUS
PANCREAS
OVARIES
These are small, oval-shaped glands located on
either side of your uterus. They produce and
store your eggs (also called ova) and make sex
hormones that control your menstrual cycle
and pregnancy.
TESTICLES (TESTES)
KIDNEYS
Your kidneys are two bean-shaped organs that filter your blood. They’re part of your urinary
system, but they also produce hormones, like erythropoietin and renin.
LIVER
PLACENTA
METABOLISM –
The endocrine system regulates the rate of metabolism, the sum of chemical
changes that occur in tissues.
CONTROL OF FOOD INTAKE AND DIGESTION –
The endocrine system regulates the level of satiety (fullness) and the
breakdown of food into individual nutrients.
WATER BALANCE –
The endocrine system regulates water balance by controlling solutes in the
blood.
HEART RATE AND BLOOD PRESSURE REGULATION –
The endocrine system helps regulate the heart rate and blood pressure and help
prepare the body for physical activity.
CONTROL OF BLOOD GLUCOSE AND OTHER NUTRIENTS –
The endocrine system regulates the level of blood glucose and other nutrients
in the blood.
CONTROL OF REPRODUCTIVE FUNCTION –
The endocrine system controls the development and function of the
reproductive systems in male and female.
NAME: BINALLA, REGINE T.
NEUROENDOCRINE SYSTEM
The neuroendocrine system is a complex network of interactions between the nervous system
and the endocrine system. It involves the release of hormones by specialized cells in response to
signals from the nervous system. These hormones then regulate various physiological
processes in the body, such as metabolism, reproduction, stress response, growth and
development, and fluid balance.
Metabolism
Hormones such as insulin, glucagon, and thyroid hormones regulate energy metabolism,
nutrient uptake, and storage.
Reproduction
Hormones such as estrogen, progesterone, testosterone, and follicle- st imulating
hormone (FSH) regulate reproductive functions, including menstruation, ovulation,
and sperm production.
Stress Response
Hormones such as cortisol and adrenaline (epinephrine) are released in response to
stressors, helping the body respond to challenges by increasing heart rate, blood
pressure, and energy availability.
Growth and Development
Growth hormone (GH) and other growth factors play key roles in cell proliferation,
different iation, and t issue growth, influencing overall growth and development from
childhood through adulthood.
Fluid Balance
Hormones such as antidiuret ic hormone (ADH) and aldosterone help regulate fluid
balance and electrolyte levels in the body, ensuring proper hydration and blood
pressure regulation.
1. Lipid-Soluble Hormone
Lipid-soluble hormones are hormones that are soluble in lipids (fats) and therefore can
easily pass through cell membranes. These hormones include steroid hormones (such
as cortisol, estrogen, and testosterone) and thyroid hormones (such as thyroxine, or T4,
and triiodothyronine, or T3).
Unlike water-soluble hormones, which cannot pass through the cell membrane easily
due to their polar nature, lipid-soluble hormones can diffuse direct ly across the lipid
bilayer of cell membranes. Once inside the cell, they bind to specific receptor proteins
located in the cytoplasm or nucleus. The hormone-receptor complex then acts as a
transcription factor, direct ly influencing gene expression and protein synthesis within
the target cell.
Due to their ability to direct ly affect gene expression, lipid-soluble hormones often
have slower but more prolonged effects compared to water-soluble hormones, which
typically act more rapidly through cell surface receptors and second messenger
systems.
2. Water-Soluble Hormone
Water-soluble hormones are hormones that are soluble in water but not in lipids (fats).
These hormones include peptidehormones, protein hormones, and catecholamines.
Peptide hormones and protein hormones are composed of chains of amino acids, while
catecholamines are derived from the amino acid tyrosine. These hormones cannot pass
through the cell membrane easily due to their polar nature. Therefore, they typically
bind to specific receptors on the surface of target cells.
Hormonal Stimuli
Hormone release can also be regulated by other hormones. This form of regulation involves a
cascade of hormonal signals, where one hormone st imulates or inhibits the release of another
hormone from an endocrine gland. For example, the hypothalamus secretes releasing and
inhibiting hormones that regulate the secretion of hormones from the pituitary gland, which
in turn st imulates other endocrine glands to release their hormones.
Humoral Stimuli
This type of regulation involves changes in the concentration of certain ions or nutrients in
theblood. When blood levels of a particular substance deviate from the normal range, it can
trigger hormone release to restore homeostasis. For example, the secretion of insulin by the
pancreas in response to high blood glucose levels is an example of humoral st imuli.
Neural Stimuli
Some hormones are released in response to neural signals. Nerve impulses can st imulate or
inhibit hormone secretion from certain endocrine glands. For instance, the release of
adrenaline (epinephrine) from the adrenal medulla in response to stress is regulated by neural
st imuli from the sympat hetic nervous system.
These three types of st imuli work together to maint ain hormonal balance in the body and
regulate various physiological processes.
INTRODUCTION
Endocrine glands are specialized organs in the body responsible for producing and
secreting hormones directly into the bloodstream. These hormones then travel throughout the
body to regulate various physiological processes, such as metabolism, growth and
development, reproduction, mood, and stress response.
Hormones are chemical messengers produced by glands in the endocrine system and
released into the bloodstream. These molecules travel throughout the body and exert specific
effects on target cells or organs, regulating various physiological processes and maintaining
homeostasis. Hormones play crucial roles in coordinating growth and development,
metabolism, reproduction, mood regulation, and responses to stress and environmental
changes.
HYPOTHALAMUS
The hypothalamus is in the lower central part of
the brain. It links the endocrine system and nervous
system. Nerve cells in the hypothalamus make chemicals
that control the release of hormones secreted from the
pituitary gland. The hypothalamus gathers information
sensed by the brain (such as the surrounding temperature,
light exposure, and feelings) and sends it to the pituitary.
This information influences the hormones that the pituitary makes and releases.
PITUITARY GLAND
Adrenocorticotropin (ACTH)
Essential for the growth of the adrenal cortex, It stimulate the adrenal glands to
release cortisol.
Prolactin (PRL)
stimulates the development and growth of the mammary glands and milk production
during pregnancy. The sucking motion of the baby stimulates prolactin secretion.
Oxytocin
Stimulates the uterus to contract during labor and delivery. It also stimulates the
mammary glands to release milk.
Human body also produce oxytocin when we're excited by sexual partner, and when
experience love.
PINEAL GLAND
Pineal gland, also called the pineal body or epiphysis
cerebri, is a tiny gland in your brain that’s located beneath the
back part of the corpus callosum. It secretes the hormones like
melatonin and serotonin. Pineal gland’s main job is to help
control the circadian cycle of sleep and wakefulness by
secreting melatonin.
SECRETIONS FROM PINEAL GLAND
Melatonin
Communicates information about environmental lighting to various parts of the body.
Has some effect on sleep/awake cycles and other biological events connected to them, such
as a lower production of gastric secretions at night.
Serotonin
A neurotransmitter that regulates intestinal movements and affects appetite, mood,
sleep, anger, and metabolism.
Serotonin is often called the body's natural "feel-good" chemical because it makes a person
feel happy and calm at normal levels.
THYROID GLAND
Thyroid Gland
The thyroid gland produces hormones that regulate
the body's metabolic rate, growth and development. It plays
a role in controlling heart, muscle and digestive function,
brain development and bone maintenance. Its correct
functioning depends on a good supply of iodine from the
diet.
Calcitonin
Calcitonin is a hormone that your thyroid gland makes and releases to help regulate
calcium levels in your blood by decreasing it
Thyroxine (T4) and triodothyronine (T3):
essential to BMR – basal metabolic rate (the rate at which a person’s body burns calories
while at rest); influences physical/mental development and growth.
PARATHYROID GLAND
Parathyroid Gland
Parathyroid glands produce parathyroid
hormone, which plays a key role in the
regulation of calcium levels in the blood.
Precise calcium levels are important in the
human body, since small changes can cause
muscle and nerve problems.
THYMUS
ADRENAL GLAND
Adrenal Gland
Also known as suprarenal glands, are small,
triangle-shaped glands that are located on top of each
of two kidneys. They’re a part of endocrine system
and produce certain hormones that help regulate several important bodily functions,
including:
Metabolism
Immune system
Blood pressure
Response to stress
Development of sexual characteristics.
The triangular-shaped adrenal glands are located on the top of each kidney. The inside is
called the adrenal medulla and the outside layer is called the adrenal cortex.
Cortisol
Regulates carbohydrate, protein, and fat metabolism; has an anti-inflammatory effect;
helps the body cope during times of stress, also known as stress hormone.
Aldosterone
It is a hormone that plays a central role in regulating blood pressure and the levels of
sodium and potassium (electrolytes) in blood. This means aldosterone helps regulate blood
pH (how acidic or basic it is) by controlling the levels of electrolytes in blood
Androgens
Several hormones including testosterone; they promote the development of secondary
sex characteristics in the male. Androgens are usually thought of as male hormones, but the
female body naturally produces a small amount of androgens too
Dopamine
Is a type of neurotransmitter and hormone. It plays a role in many important body
functions, including movement, memory and pleasurable reward and motivation.
Epinephrine
Is also called adrenalin. It elevates systolic blood pressure, increases heart rate and
cardiac output, speeds up the release of glucose from the liver… giving a spurt of energy,
dilates the bronchial tubes and relaxes airways, and dilates the pupils to see more clearly. It is
often used to counteract an allergic reaction.
Norepinephrine
like epinephrine, is released when the body is under stress. It creates the underlying
influence in the fight or flight response. While epinephrine has slightly more of an effect on
your heart, norepinephrine has more of an effect on your blood vessels
NAME: PRADO, JONARD P.
SUBJECT: ANATOMY AND PHYSIOLOGY
TOPIC: ENDOCRINE SYSTEM
HYPERTHYROIDISM
Hyperthyroidism happens when your thyroid gland makes more thyroid hormones
than necessary. This can be caused by a range of things, including autoimmune conditions.
Treatment depends on how severe the condition is, as well as its underlying cause. Options
include medications, radio iodine therapy, or surgery.
Graves‘ disease is an autoimmune disorder and a common form of hyperthyroidism. In
people with Graves‘ disease, the immune system attacks the thyroid, which causes it to
produce more thyroid hormone than usual.
HYPOTHYROIDISM
Hypothyroidism occurs when your thyroid doesn’t produce enough thyroid hormone. Similar
to hyperthyroidism, it has many potential causes.
Fatigue
Weight gain
Constipation
Issues tolerating the cold
Dry skin and hair
Slow heart rate
Irregular periods
Fertility issues
CUSHING SYNDROME
Cushing syndrome happens due to high levels of the hormone cortisol.
Weight gain
Fatty deposits in the face, midsection, or shoulders
Stretch marks, particularly on the arms, thighs, and abdomen
Slow healing of cuts, scrapes, and insect bites
Thin skin that bruises easily
Irregular periods
Decreased sex drive and fertility in males
Treatment depends on the cause of the condition and can include medications, radiation
therapy, or surgery.
ADDISON’S DISEASE
Addison’s disease happens when your adrenal glands don’t produce enough cortisol or
aldosterone. Some symptoms of Addison’s disease include:
Fatigue
Weight loss
Abdominal pain
Low blood sugar
Nausea or vomiting
Diarrhea
Irritability
A craving for salt or salty foods
Irregular periods
Treatment for Addison’s disease involves taking medications that help replace the hormones
your body isn’t producing enough of.
DIABETES
Diabetes refers to a condition in which your blood sugar levels aren’t regulated within a
certain range.
People with diabetes have too much glucose in their blood (high blood sugar). There are two
types of diabetes: type 1 diabetes and type 2 diabetes.
Fatigue
Increased hunger or thirst
Frequent urge to urinate
Irritability
Frequent infections
Treatment for diabetes can include blood sugar monitoring, insulin therapy, and medications.
Lifestyle changes, such as getting regular exercise and eating a balanced diet, can also help.
Irregular periods
Fertility issues
Cysts that form on the ovaries
Acne
Hirsutism, which is an unusual amount of hair growth on the face or chin
Thinning hair
Weight gain
Skin tags
Treatment for PCOS focuses on easing the symptoms. Treatments include medications, like
birth control and metformin, and lifestyle changes, such as focusing on nutrition and trying to
reach a moderate weight if your doctor has recommended it.
HYPOGONADISM
A common condition, especially in older males and occasionally in females, hypogonadism is
caused by a lowered production of the sex hormone testosterone. This can lead to lowered
libido, as well as a variety of other symptoms, such as:
OSTEOPOROSIS
Osteoporosis is an abnormal loss of bone mass and changes in bone tissue. It can be caused
by a variety of issues, but two common causes are lowered estrogen levels in people with
ovaries and lowered testosterone levels in people with testicles. These lowered hormone
levels can be caused by age, as well as other diseases.
Osteoporosis doesn‘t always cause obvious symptoms. But some of the more common
symptoms are bone fractures and injuries related to minor falls, lifting, and even coughing.
Treatment for osteoporosis focuses on slowing or stopping bone loss. Proper nutrition,
exercise, and medications are three of the most common treatments.
ACROMEGALY
This rare disease is caused when the body makes too much growth hormone, which is mainly
produced in the pituitary gland. Mostly diagnosed in middle-aged adults, it can cause organs,
bones, cartilage, organs, and certain tissues to grow in size.
Swollen nose
Swollen ears
Swollen hands and feet
Joint aches
A deeper voice than usual
An increase in sweating and body odor
Treatment for acromegaly includes medications, radiation therapy, and surgery
MENOPAUSE
Menopause is a natural process that occurs when a woman's ovaries stop producing eggs and
her menstrual cycles cease. It is associated with a decline in estrogen and progesterone levels,
leading to symptoms such as;
Irregular menstrual cycle
Hot flashes
Night sweats
Vaginal Dryness
Sleep disturbances
Mood changes
Fatigue
Weight gain
Changes in libido
Joint pain and muscle aches
Memory problems
GYNECOMASTIA
This condition involves the development of breast tissue in males due to an imbalance of
estrogen and testosterone hormones. It can occur during infancy, puberty, or later in life due
to various factors such as hormonal disorders, medication side effects, or certain health
conditions.
Before pursuing any treatment for gynecomastia, it's essential to consult with a healthcare
provider for proper evaluation and guidance. Treatment recommendations will depend on the
underlying cause of gynecomastia, overall health status, and individual preferences.
Additionally, regular follow-up appointments may be necessary to monitor treatment
effectiveness and address any concerns or complications.
DELAYED PUBERTY
Delayed puberty occurs when the onset of sexual maturation is significantly later than usual.
It can result from hormonal imbalances affecting the production of estrogen, progesterone,
testosterone, or growth hormone.
It's essential for individuals with delayed puberty to undergo a comprehensive evaluation by a
healthcare provider to determine the underlying cause and develop an appropriate treatment
plan. Treatment decisions should be individualized based on the specific needs and
circumstances of each person, and regular follow-up appointments may be necessary to
monitor progress and adjust treatment as needed.