Alcohol Phenol Ether RAFTAAR Nitesh Devnani

4 DAY CHALLENGE
DAY 8MARKS
* HALOALKANES HALOARENES
->
1
MARKS
* ALCOHOL PHENOL ETHER DAY2- 12
DAY 3 12 MARKS
* ALDEHYDE KETONES CARBOXYLIC -
-
-
* AMINES DAY 4
#COMMENT
RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

Alcohol Phenol Ether
12 MARKS
RAFTAAR 2.0
DAY 7

↑
USE CODE
GNT77
*

~
-
Y

31St MARCH
Link
YALGAAR TEST
↳
↓
FREE #
·
Solution
·
Kinetis
-
Elchochemisby
· -
·
coordination

E
* ALCOHOL H
-
" ALCOHOL
CHz-CH2-CHz-O4 CH2-OH
I
glycol
Ethylene
ALCOHOL
2
CH2-OH
CHz-ct
-
a
re
CH2-OH
M3
I
CH-OH
glycerol
CHz-c-on
:
Accour ins ine-on
PREPERATION ALCOHOL
OF
*
CIC
1 FROM ALKENES
Addition
Acid
*
catalysed hydration of I
H20
H OH
OMDM
*
HBO
*

ACID CATALYSED HYDRATION
Reagent:-dil. H2SO4 FLOW Y

*
formation
or
Cabocation
*
H44,0 ↑
or
Rearrangement possible
*
H30 OH add
*

dil-
on
1
e cuz
Crez-c-H
CH3
=
My
Ens
- -
MeSOn
30 ALCOHOL
F
H on-
Cr-cH-H-Ms Cuz-c-a-M3
ins 20
Ch, 3"

Ar-Mucuation
OMDM
Ony Mecuation
Addition
-> of water
-
On-
H
4t i) HgCAc2/4,0 I
R CH2
R-ch-nee
CH
=
-
OH if NaBHy
I
source on:-420
of
Source
of H:-NaBHy

Mainfonts
-
(OMDM)
Anti addition
Additionof water
->
Markovakov'srule-on added where his 4

⑧
* is
-
rearrangement
-
- No
-
A No Carbocation
-
--
S
intermediate
·
Cycle
*

In2
on-
en
/nzo
i) HgCAC2
CH3-ch-cr=
*
ii)
chance
an
Waste
diy out
n+
o
t
1D28 M
n
i) AgCAcla
CHz-cH CH2 CHy-CH M2
=
-
*
op-OD-
) NaB os
Hg(Acal a
20 D
i)
NaBDY
itiy
Chy-inma
Ovidation
do Boration
HBO
my
of
Addition
watery Bat-THE R CH M2
-
R CH CH2
-
=
-
nt on it 4202/On- H OH
OH-
on: -Mauz/ou-
of
source
Samber
of Mi-Batts

Maint
addition
Addition
*
of water Syn -
-
>
on added
is
where more
4
Anti Markownikov
->
* rule
>
No caboration
Arearrangement
-
*
-
-
⑥
addition
Syn
*
intermediate
Cyclic
**

CH31c= Bato/nF
-at
i)
e isreason chec -
Ma
als as i on
i) BY THE
ifnot
3-e
*
REAGENT
2) FROM GRIGNARD GRIGNARD
Crz-c-c+
Mg he CHS-Mga-
Halide
Alkyl
↳ngx
reactive
Part

CH3
-jEnzrgie
O
St I
4 H- c ↑ ALCOHOL
*
4
S 4
- -
-
2 ii) n+H20 on
-
6-8
FORMALDEMYDE
+2 -
Cus
St
izMgr R
I
C
O
2 ALCOHOL
Res
H
- -
*
-
ii] IH20
-
on
HT
ALDEHYDE
-Finzig
St Br M3 &
3 ALCOHOL
E i)n+1420
Ru
A R -
C -
R -
I
KETONE On

NOTWA
Canon X
change EWG
on
Rate
of tire
run a
-
--
-
EDG
-
Rate ofdete
X
Steric hindrance
--

COMPARERATE
OF RXN: -
In-g-n7 ag-
e <Mg-M3
⑧
0
11 11
2) Toc-n
--
>
Ta-ms
R
7 ge
R-
-
ALDEHYDE YETONE

CHO CHO
I I
3) --
ToT [ 10 I
R
- -
+R oi Nos
-
EWG
EDG
⑧ ⑧
It
-
4) ↑T>
- 11

REDUCTION
3) REACTION
↳
My NBMyMa, Od
Addition
of He
-

LiAlty or NaBMY
4
I
H C 1 ALCOHOL
Me
- ->
- -
in
or My 1Ni
LiAte o NaBHy
" ALCOHOL
Cra
H CHI
-
-
-
Mr M21Pt
LiAlty or
NaBHy
143 M, "ALLONOh
-
②
CH3
u
--
e
-
or Ha (Pt -

2 STEP PROCESS
4 H LiAlty or NaBHy
c
CHI Ha+M-4
-
-
or H2/Ni
H H LiAlHy
"rz-cr-on
↳
420
243-4
CHz- OH
i
->
+
-
or H1Pt
ACID
HH
↳ Crz-M-04
LiAlHy
CHz-c-0- C43-on-Cr-c-
-
Mr
H2/Ni
ESTER
CHz-c-yoy1
NaBHy
* cannot reduce
ester
i)
Acid
ii) Carboxylic
ii) Anhydride

A ACIDIC NATURE
R 10 H
0-4
+
-
Audi

Na
R OrNat
- I
M2
I
I
R-OH --
--
z R-oNat
-
->
+
NH3
↳ R-oNat
t -
Nat + M2
-

formationof estee
-
⑰ ESTERIFICATION
I
cous.
Acid + Alcohol istu +
40
H2SO4
OH H
CATALYST
fruity
smell
CARBOCATION
ch-s-on
t
Ho-CH5
Alcohol
rousin cr-i ~O-Cz45 I
420
ester
Acid -

-on 4018
come.
no- C245 ->
+
4250 y
Alcohol
I
a 2245
4
-
0
- -
ate
=
Rate
- of Rux-
ED42 WRT ACID
ENG
Rate Ran -
-2
of =>
Sturic hindrance
WRT ALCOHOL

COMPARE RATE
OFESTERIFICATION
COOM COOM COOM

I
--
I
--
I
--
27371
&1 10 I
--
10 I
--
R
-
nis -Rome ins +
H
Rate Run h
of
X
EwG

of CH3-My-Mz-M2-04 Rate Run -
of -
stuvi
az-as-cheste 1> 273
us
ag-c- o4
ins Mor
stai
-

Intermediate
*
A LUCAS REAGENT TEST
↳ CARBUCATION
come. HCL
R -
ON I
R-c
Zucker TURBID
awhy.
CATALYST
--
Recurly 3- 27
--

wide
A DARZEN'S REACTION Thionge
CH3 ↑ CH3
SOC2
H 04 H c SO24
+ +
of
Retention
↑
HUN
Catty Catty
Configuration
-
SNi By Product
Best Method
* CASES

REACTION WITH PX3 PU3 PBR3 P13
A
Pus
R 04
-
R-c
A REACTION WITH PX5 PUG PBIS P15
&- C
Re + Ha
- n
POUs
+
ux c
p-
-
a
a ↳
VVVVVIMP Removal
A) DEHYDRATION -
of M20
En Es
Audie
come. H2SO4/D Go BO5 /A
1)
condition's
come. MyDOn IA
2)
I
2) Al2O3 /9
3) 1420,
H 1
⑪ POUz/D
3)
CC
*
formation ⑧
Most
*
stable albene
Rearrangement possible MAJOR

*
->
Most stable alkene
*
MAJOR
-
-

CH3
I M3
Crz-c-in, concisee Cus

-
Ins
=c -
Mz
E
4
L
M3WI 1
+
az
Crz-c-cH-M3 CHz-p-cy-cus
ins 20
M3 30

eff
Cr--a
AosID
* &By Major
Ear
Muneauener
<Be crs- -u M2 =
Less
M3 /4 stable
Hoffmann Minor
-

ALCOHOL
OF ALDEMUDE
KELONES
A OXIDATION
R-CH-CH,-o4 adsig
strong R-cr-COON Ad
-
DO ALCOHOL
Mild
ondising
-
R-CH2-,
-
agent MOA or wor Aldehyde

-

SOA
R-c
Ketone
-
& -
or MOA
20 ALCOHOL
R
SOA
ocidation
1
or
R -
C -
R No
MOA
on
-
30 ALCOHOL

STRONG OXIDISING AGENTS
I KMnOn Int
2) KaG07 Int
Reagent
=> Jones
3) GOz +
HaSOn
4) cons.
HNO3

MILD OXIDISING AGENTS
I cull or Clsoo
Agla or
Ag/300
chromate)
2) PCC
(Pyridinium chloro
3) Collin's
Reagent 7) Brat Water
4) Sarett's Reagent (Bromine water)

5) NBS
6) DDC

Cu/A
-on
Aldhyde
I
-- -
I alcohol MOA
GelA
i --
on calcohol
mon-IT ketone

MnOw
no
*
1 Cr-CH= cy-my- c,-04
win X
MnOC
MOA
Mld odisingagent &
-CH=CH-c-ca-o
only for allylic
acudation
CH2=cH-Na- MnOn
allylie
ATRANG
-
CH3 CH2
I se 11
Alkene
CHz-c 04
-
C
A Ms -
ins elimination
I
M3
30 AL2O4Ob 420
-

A
--H
* PHENOL
101
--
PREPERATION
From Benzene Sulphonic

⑰) Ad
O'Nat On
SOzH I
I
E
I NaOH H
Eit
--
!
->
A
I
Sodium
Phenoxide
2) From
Diazonium salt
WARM on
Nata-
I
N2
↑
HC 1
H20
liT
NaNOz +
E N2
-- +
--
↳ or
On- -
HMO2
Aniline ↑
Diazonium Phend
salt
- Nitrous
Acid 0-5°C
3) From
Benzene (oxidation) of
V205 -
[O] 1 ⑧ I
lol
-->
+
-
PHENOh
-

4) From Haloarenes
Dow's process Nat Or

T
u
623k
I
H -
I-
I /
--
I O I NaOH
+
-
m
I it
- / Phenol
--
WAS x EWG -
ED4
Nucleophilic Aromaticsubstitution

WVVVIMP PuD
5) From Cumene -
Cumul
C43-cr-M3 IM3 -
I
M3
c -
0 -
0 -
4
Acetone
Chg-g-
02
-- Ht
I 0 I
--
A
1 ⑧ I H20
- I
sopropyl sumene
Benzene
O
-
Hydrofonde I
--
8 I
Phenol
NCERT
-

A CHEMICAL PROPERTIES
ACIDIC NATURE
Of
I
O-
I
Acidic
Ht
[
--
t
> 1111
GOC --
↑ Acidic
strength EWY
-Y

H-BONDING TORTHO
If
*
NITRATION MAJOR
If NO H-BONDING - PARA
Bandit
*
MAJOR
a) Dilute HNO3
On 11 on
↑ - 0
o or - I
-
minigi + dil. HNO3 ->

1
--
⑧
I ↳
Nost Metroplite URTHO
-
Now
Myou PARA
MONOSUBSTITION
Mind
-

5) come. HNO3 TRISUBSTITUTION
on
Of Nor I
I come. ---NO2
/
--
/
I-- 11 -
I -
11 Picrie
HNO3 --
I And
NOzT NO2
-

3) HALOGENATION
OH
old on
of Brz But I
A
I - Br
MONOSUBSTITUTION 1
--
1 ⑧ I Now PolarSolvent CS2 I

⑧
I -
⑧ I
-- Mino-
Play Brz
can ORTHO
Majore
PARA
solvent OH
By T
o TRISUBSTITUTION
Bt 11
BE
II
I I
6
0
2,4,6-TriBromo 3
WHITE
-- PPT
Phena 5 4
Be -

- CARBOCATION
↳) ESTERIFICATION -
Estrification
cone.
And t Alcohol ste I 40

H2SO4
Acid
Hydrolysis of
estr +
40 + Alcohol este
A
of estification-- Ih
Rate
EWG
Rate
of hydrolysisof wh
ester a
EDY

ASPRIN FORMATION
COOH
--4
M,-gro-cs->chy-t
+
10 1
-- COON
I
I-Forg
--
I
Asfre
WVVVIMP
REIMER-TLEMANN REACTION -
-
of
->CHLOROFORM 04... 11
Hug On
Of
--
I CHU3 I
---
c
-
H --
A
I--
0 lomno 10 1
-
I ⑧ I
NaOH or KOH
+
--
-- PARA
PHENOL Basic
kno
Saliyaldehyde
-
condition
MINOR
MAJOR

MECHANISM
a
u
40+a-c-
I
u -c -
H + on --
↳ a
oibitst
emply
-
d
Krug a
⑧ 8
(F
> -
be
al
Dichlow - 8
cabene e-defint
ELECTROPHILE
E

Or o'Nat
Phenoxide
&
- NaOH --
↑ sodum
1 ⑧ I - -
-
I ⑧ I -
--
Latomer
-
0 04
8 I
i
H
·CC2 1spe -can
-
-
Il
Int
-- I
I--I
↳
11
-
Fran -
- AROMATIC
NON AROMATIC
- Or
E
O
OH
I
X-cno OH- -crus
I'I
--cx11
12 I
-
--
-
-
I
E
2 -

Main Points. -
↳ Ortho
M E
Para
↳
occupied major
is then
If other =
/
on on
I
pat-als
I
CHU3
markon
--M3
↳
--

(g)-
0-
o
-10
O
It
i won
(yet) Salige
won
-

KOLBE'SREACTION
or
04 1) Noon X-cOOn
I ⑧ I
--
-
10 I 2) CO2
-- --
PHENOL
3) Ht
Sallylie ed

PHENOW
A REDUCTION OF
Benzene
⑭ -
- Zu
II dust
IT
--
+ zw0
~
Bergen

OXIDATION OF PHENOL
O
OH
I Naz G207 - Pare Buzoquinone
Ei --
H2SOY 11 Il
PHENOG
or
GOCU2 -
chide
chromy

BETHERS Y
R1-O-R2
Mz-0-M3 ->
symmetrical
R, R2
=
ethers
simple others
mixed
Mz-0-M, My- unsymmetrical ethers there
->
R, FR2
->
-(3
Anisole
-> -
or
mithory
Benzene
-

* PREPERATION ETHERS
OF
1) Dehydrationof
Alcohols
(Temperative defendent
Core. H2SO4
ALKENE (r
=M2
- 77 170°C
Mz-m- 04 come. HeSOY

--
7 = 140°
ETHER C4z-c-0-4-13
1-
ALCOHOL
core. H2SO4 ALKML

HYDROGEN
CHz-cson
-110
SULPHATE

2) Williamson Ether
Synthesis:-SN21x's
RONat
isx
-
-> NaX R-O-R

the
go
Ro-Nat
*1x- NaX R!O-R
+
po ther

onlat 143-0-c,-M3
CHz-c
po u3
cuz-i-o-mat M3
An
arz-Be M43-0-2 M3
-
⑧
A
as

M3
Cz0Nat Cha
as-c-
11
a --
-
elimination C
us M3 -
3 1 Alken
Dehydrohologration
S
alkyl Valle My
->
g
-i7 23 mixture
SN2:
-
of SN$dlunation
EE*:-32,
COMPOUNDS WHICH DOES NOT GIVE
WILLIAMSON SYNTHESIS
halide Bridge head 2 X

soalkyl
*
Sp
·never
head con
·
>
-
Bridge be plane
--
↳
Partial
* Double Bond ·
Reso
⑥
... AB
Partist
CH2 CH a
= -
e
18

with
Reaction
3)
AgcO
ado
R -
X ETHER R-O-R
AgeO 420
+
&
most
↓
Agoy
Aga8
R-OH
ALCOHOL
->

CHEMICAL PROPERTIES
A
with Vvmp
If Reaction MX
R, RC
SNA If any of or can
R. -0-Ra + HX
stable carbocation
ETHER form
-
-
SN2 LESERRIC 33"
=
or resonance
-
stabalised)
-
the attack on that
Preference of
X
attack ⑫
is on less sterric
~

0
1 t
- I -
ne
CHz-0-M, -M3 cuz-x
no-m,Ms
2 +
Less I Mor SN
a 4 -
swi
stric
it 20
HBr
-
Mz-0-CH-M3 as +
no-M-M3
I SN2
Br H
M3 Br Ms

n M3
,03
Mz-0-c M3 I
-
HB
Cuz-on
+
Br-c-ms
SN'
-
Br
cus
-
4
M3
t -
HI
---M,-0-M2M3
Asus
/ +
I I
-
-
- I
4 SN nocuzy

20 A
,
HBU
-
o-M,-M3 Cz-y-o4
Mg-ce
-
I
SN2
t +
Br-M,-M3
cus
*
)
Partial
geo&
It
e
HI
↳) -
on +
C-MI-I
DB

reso
[]in)
HI
↳)-on
↓n It
1-c)
+
+
Particl
AB
reso
M3
[]S- HB
-)on
-
Ms
-
↓it sit -M3

Partial M3
BC
+
M3
-
DB
I
C3
E
Excess
of
*
Mx
it a
HBr
-- CHI-BY
+
40-M,M3
I
excess
Be H
SNC HBr
Br-a
z

Partial
e
us HI
Gmedo
&)
L
&
excess
a
n1
+ T
xt+
Partial
DB
eg-a-I
[7-1
Ether
2) Hydrolysis of
NOTWA:-Proved throughmost stable Carbation
po- po
SCHION no-a-M3
+2
I
M3-0-c,C,
I
H OH

at-a-M3 i >104
y +
no-a,M3
items I Dox no-de

+

⑧
t
ELECTROPHILIC AROMATIC SUBSTITUTION
e.at

I
CH3
-
Cuz-c
--

I
NOG

#REACTION WITH PU5
S 2
Rich I Rach
Ri -O-Ra
a
p -
u
POUs
-
a Ch

#REACTION WITH CHLORINE
i , C2
CH
a5M-0-M2-Mg CHz-CH
O-
My
-
-
Oa
&
↓
U2
I
hV
CCz-C42-0-CU,-[Uz

Alcohol Phenol Ether RAFTAAR Nitesh Devnani

Uploaded by

Document Information

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Alcohol Phenol Ether RAFTAAR Nitesh Devnani

Uploaded by

Copyright:

Available Formats

4 DAY CHALLENGE

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

Reagent:-dil. H2SO4 FLOW Y

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

Markovakov'srule-on added where his 4

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

COOM COOM COOM

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

A REACTION WITH PX5 PUG PBIS P15

Rearrangement possible MAJOR

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

Crz-c-in, concisee Cus

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

agent MOA or wor Aldehyde

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

4) Sarett's Reagent (Bromine water)

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

From Benzene Sulphonic

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

Dow's process Nat Or

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

minigi + dil. HNO3 ->

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

1 ⑧ I Now PolarSolvent CS2 I

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

And t Alcohol ste I 40

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247

RAFTAAR 25 days = 25 chapters t.me/neetpreparationadda247