Contents

Stroke ............................................................................................................................................................ 2
What is a stroke? ........................................................................................................................................... 3
Treatment...................................................................................................................................................... 3
Ischemic stroke ............................................................................................................................................. 3
Hemorrhagic stroke....................................................................................................................................... 4
Rehabilitation ................................................................................................................................................ 4
Prevention ..................................................................................................................................................... 5
Causes and risk factors .................................................................................................................................. 6
Ischemic stroke ............................................................................................................................................. 7
Hemorrhagic stroke....................................................................................................................................... 7
TIAs................................................................................................................................................................ 8
Symptoms ..................................................................................................................................................... 8
Diagnosis ....................................................................................................................................................... 9
References................................................................................................................................................... 11
Stroke
occurs due to a decrease in oxygen to the brain. This can be due to a bleed or blockage in the
brain’s blood supply. Immediate emergency treatment may help prevent life threatening
consequences.

Stroke is the fifth leading cause of deathTrusted Source in the United States. In fact,
nearly 800,000 peopleTrusted Source have a stroke each year. That equates to around one person
every 40 seconds.

There are three main typesTrusted Source of stroke:

• Ischemic stroke: This is the most common type of stroke, making up 87% of all cases. A
blood clot prevents blood and oxygen from reaching an area of the brain.

• Hemorrhagic stroke: This occurs when a blood vessel ruptures. These are usually the
result of aneurysms or arteriovenous malformations (AVMs).

• Transient ischemic attack (TIA): This occurs when blood flow to a part of the brain is
inadequate for a brief period of time. Normal blood flow resumes after a short amount of
time, and the symptoms resolve without treatment. Some people call this a ministroke.

Stroke can be fatal. According to the American Heart Association (AHA), the age-adjusted
mortality rate for 2017 was 37.6 in every 100,000 stroke diagnoses. Doctors have made a great
deal of progress in managing strokes, meaning that this mortality rate is 13.6% lower than it was
in 2007.

This article explains why strokes occur and how to treat them. It also explores the different types
of stroke, as well as the steps a person can take to prevent them.
What is a stroke?

A stroke occurs when a blockage or bleed of the blood vessels either interrupts or reduces the
supply of blood to the brain. When this happens, the brain does not receive enough oxygen or
nutrients, and brain cells start to die.

Stroke is a cerebrovascular disease. This means that it affects the blood vessels that feed the
brain oxygen. If the brain does not receive enough oxygen, damage may start to occur.

This is a medical emergency. Although many strokes are treatable, some can lead to disability or
death.

Treatment
Because ischemic and hemorrhagic strokes have different causes and effects on the body, both
require different treatments.

Rapid diagnosis is important for reducing brain damage and enabling the doctor to treat the
stroke using a suitable method for the type.

The sections below cover the treatment options for ischemic stroke and hemorrhagic stroke, as
well as some general rehabilitation tips for both types.

Ischemic stroke
Ischemic stroke occurs due to blocked or narrowed arteries. Treatment tends to focus on
restoring an adequate flow of blood to the brain.

Treatment starts with taking drugs that break down clots and prevent others from forming. A
doctor may administer blood thinners such as aspirin or an injection of tissue plasminogen
activator (TPA).
TPA is very effective at dissolving clots. However, the injection needs to take place within 4.5
hoursTrusted Source of the stroke symptoms starting.

Emergency procedures include administering TPA directly into an artery in the brain or using a
catheter to physically remove the clot. Research is ongoing as to the benefits of these procedures.

There are other procedures that surgeons can perform to reduce the risk of strokes or TIAs. A
carotid endarterectomy, for example, involves opening the carotid artery and removing plaque
that could break and travel to the brain.

Another option is angioplasty. This involves a surgeon inflating a small balloon inside a
narrowed artery using a catheter. Afterward, they will insert a mesh tube, or a stent, into the
opening. This prevents the artery from narrowing again.

Hemorrhagic stroke
Blood leaking into the brain can cause a hemorrhagic stroke. Treatment focuses on controlling
the bleeding and reducing the pressure on the brain.

Treatment often begins with taking drugs that reduce pressure in the brain and control
overall blood pressure, as well as preventing seizures and any sudden constrictions of blood
vessels.

If a person is taking blood-thinning anticoagulants or antiplatelet medication, such as warfarin or

clopidogrel, they can receive medications to counter the effects of the blood thinners.

Surgeons can repair some of the problems with blood vessels that have led or could lead to
hemorrhagic strokes.

When an aneurysm — or a bulge in a blood vessel that may burst — causes a hemorrhagic
stroke, a surgeon can place small clamps at the base of the aneurysm or fill it with detachable
coils to stop the blood flow and shrink the aneurysm.

If the hemorrhage occurs due to an AVM, a surgeon can remove it. AVMs are connections
between arteries and veins that can be at risk of bleeding.

Rehabilitation
Stroke is a potentially life changing event that can have lasting physical and emotional effects.
Successful recovery from a stroke will often involve specific therapies and support systems,
including:

• Speech therapy: This helps with problems producing or understanding speech. Practice,
relaxation, and changing communication style can all make communicating easier.

• Physical therapy: This can help a person relearn movement and coordination. It is
important to stay active, even though this may be difficult at first.

• Occupational therapy: This can help a person improve their ability to carry out daily
activities, such as bathing, cooking, dressing, eating, reading, and writing.

• Support groups: Joining a support group can help a person cope with common mental
health issues that can occur after a stroke, such as depression. Many find it useful to share
common experiences and exchange information.

• Support from friends and family: Close friends and relatives should try to offer
practical support and comfort after a stroke. Letting friends and family know what they
can do to help is very important.

Rehabilitation is an important and ongoing part of stroke treatment. With the right assistance and
the support of loved ones, regaining a normal quality of life is usually possible, depending on the
severity of the stroke.

Prevention
The best way to prevent a stroke is to address the underlying causes. People can achieve this by
making lifestyle changes such as:

• eating a healthful diet

• maintaining a moderate weight

• exercising regularly

• not smoking tobacco

• avoiding alcohol, or only drinking moderately

Eating a nutritious diet means including plenty of:

 • fruits

• vegetables

• whole grains

• nuts

• seeds

• legumes

Be sure to limit the amount of red and processed meat in the diet, as well as cholesterol and
saturated fats. Also, moderate salt intake to support healthy blood pressure levels.

Other measures a person can take to help reduce the risk of stroke include:

• controlling their blood pressure levels

• managing diabetes

• getting treatment for heart disease

As well as making these lifestyle changes, taking anticoagulant or antiplatelet medications can
also reduce the risk of experiencing another stroke.

Undergoing cardiac artery, carotid artery, or brain aneurysm surgery can also lower the risk of
additional strokes, as can some other surgical options still under investigation.

Causes and risk factors

Each type of stroke has a different set of potential causes. Generally, however, stroke is more
likely to affect a person if they:

• have overweight or obesity

• are 55 years of age or older

• have a personal or family history of stroke

• have high blood pressure

• have diabetes
 • have high cholesterol

• have heart disease, carotid artery disease, or another vascular disease

• are sedentary

• consume alcohol excessively

• smoke

• use illicit drugs

Some studies have found that males have a higher risk of death from stroke than females.
However, one 2016 review of studiesTrusted Source suggests that these differences do not take
into account adjustments for race, age, the severity of the stroke, and other risk factors.

The review explains that the risk of stroke mortality often increases due to age and demographic,
rather than the biological differences between males and females.

According to a 2016 analysisTrusted Source, African American people have a significantly

higher risk of experiencing a first-time stroke. They are also around 60% more likely to
experience another stroke within 2 years.

The following sections describe the specific causes of each type of stroke.

Ischemic stroke
This type of stroke occurs due to blockages or narrowing in the arteries that provide blood to the
brain. This causes ischemia, or a severely reduced blood flow, which damages brain cells.

Blood clots often cause ischemic stroke. Clots can form in the brain arteries and other blood
vessels in the body. The bloodstream carries these into narrower arteries in the brain.

Fatty plaque deposits within the arteries can also cause clots that result in ischemia.

Hemorrhagic stroke
Leaky or burst arteries in the brain can give rise to hemorrhagic strokes.

Leaked blood puts pressure on brain cells and damages them. It also reduces the blood supply
that can reach the brain tissue after the hemorrhage.
Blood vessels can burst and spill blood into the brain or near the surface of the brain. This may
also send blood into the space between the brain and the skull.

Having hypertension, experiencing physical trauma, taking blood-thinning medications, and

having an aneurysm can all make a blood vessel leak or burst.

Intracerebral hemorrhage is the most common type of hemorrhagic stroke. This occurs when
brain tissue floods with blood after an artery bursts.

Subarachnoid hemorrhage is another type of hemorrhagic stroke. These are less common. In a
subarachnoid hemorrhage, bleeding occurs in the area between the brain and the thin tissues that
cover it.

TIAs
TIAs only briefly interrupt the flow of blood to the brain. They are similar to ischemic strokes, in
that they occur due to clots.

People should treat them as medical emergencies, even if the symptoms are temporary. They
serve as warning signs for future strokes and indicate a partially blocked artery or clot source in
the heart.

According to the Centers for Disease Control and Prevention (CDC)Trusted Source, over a third
of people who experience a TIA have a major stroke within a year if they do not receive any
treatment. Around 10–15% of people will have a major stroke within 3 months of experiencing a
TIA.

Symptoms
The symptoms of a stroke often appear without warning. Some of the main symptoms include:

• confusion, including difficulty speaking and understanding speech

• a headache, possibly with altered consciousness or vomiting

• numbness or an inability to move parts of the face, arm, or leg, particularly on one side of
the body

• vision problems in one or both eyes

 • difficulty walking, including dizziness and a lack of coordination

Stroke can lead to long-term health problems. Depending on the speed of the diagnosis and
treatment, a person can experience temporary or permanent disabilities after a stroke.

Some people may also experience:

• bladder or bowel control problems

• depression

• paralysis or weakness on one or both sides of the body

• difficulty controlling or expressing their emotions

Symptoms vary and may range in severity.

Learning the acronym “FAST” is a good way to remember the symptoms of stroke. This can help
a person seek prompt treatment. FAST stands for:

• Face drooping: If the person tries to smile, does one side of their face droop?

• Arm weakness: If the person tries to raise both their arms, does one arm drift
downward?

• Speech difficulty: If the person tries to repeat a simple phrase, is their speech slurred or
unusual?

• Time to act: If any of these symptoms are occurring, contact the emergency services
immediately.

The outcome depends on how quickly someone receives treatment. Prompt care also means that
they would be less likely to experience permanent brain damage or death.

Diagnosis
Stroke begins rapidly. For the best outcome, a person should receive treatment at a hospital
within 3 hours of their symptoms first appearing.

There are several different diagnostic tests a doctor can use to determine the type of stroke.
These include:
• Physical examination: A doctor will ask about the person’s symptoms and medical
history. They will check muscle strength, reflexes, sensation, vision, and coordination.
They may also check blood pressure, listen to the carotid arteries in the neck, and
examine the blood vessels at the back of the eyes.

• Blood tests: A doctor may perform blood tests to determine if there is a high risk of
bleeding or blood clots, measuring levels of particular substances in the blood, including
clotting factors, and checking whether or not an infection is present.

• CT scan: A series of X-rays can show hemorrhages, strokes, tumors, and other
conditions within the brain.

• MRI scan: These use radio waves and magnets to create an image of the brain, which a
doctor can use to detect damaged brain tissue.

• Carotid ultrasound: A doctor may carry out an ultrasound scan to check blood flow in
the carotid arteries and to see if there is any narrowing or plaque present.

• Cerebral angiogram: A doctor may inject a dye into the brain’s blood vessels to make
them visible under X-ray or MRI. This provides a detailed view of the blood vessels in
the brain and neck.

• Echocardiogram: This creates a detailed image of the heart, which doctors can use to
check for any sources of clots that could have traveled to the brain.
References
• Greenberg SM, Ziai WC, Cordonnier C, Dowlatshahi D, et al. 2022 Guideline for the
Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From
the American Heart Association/American Stroke
Association (https://pubmed.ncbi.nlm.nih.gov/35579034/). 2022;53:e282-e361. Accessed
8/7/2022.

• Schwartz H, Sullivan J, Talmasov D, Safar LT. The Neuropsychiatry of Stroke. In:

Silbersweig DA, Safar LT, Daffner KR, eds. Neuropsychiatry and Behavioral Neurology:
Principles and Practice. McGraw Hill; 2021.

• Smith WS, Johnston S, Hemphill, III J. Introduction to Cerebrovascular Diseases. In:

Loscalzo J, Fauci A, Kasper D, Hauser S, Longo D, Jameson J, eds. Harrison's Principles
of Internal Medicine. 21st ed. McGraw Hill; 2022.

• Stroke and Cerebrovascular Diseases. In: Ropper AH, Samuels MA, Klein JP, Prasad S,
eds. Adams and Victor's Principles of Neurology. 11th ed. McGraw Hill; 2019