BRERST

CARCINomA OE CRENS
RIS nCTORS
FAmILY HISTORY
fuist dagnaa u l i
To esTRnNS u t broost antas ENvIRONoenTAL Føco
Rodialiodo
Totin
ENOc&HNDs
a ymuromh xookrou .Sookuna
Hodmorw
lae ropaue Caskaioma
BENIGN BeEASTDEKE
k st bhenraaunt
Pragnocy Ahpiead hypapasa
hobua a n sbu
ProiP braos dueae*
RACE uit algpa
ie-e Age
Rapro as
paleso broas dena
.Broudarg_
No sPenAL TUPE (NST)
NVGSIV CT9L CARUNoro
mundla ard be
karge casuiromoan ioitvaa pechvmlun

prdsua daingara stao

iode io donnis -cauDa bmdtuo
bumos in cenbral patrbo o braast
ataptar,1
Tarl maasans v a mda os olitant
- diff t daback palpaoo/mamgram
caaora s r a l

fasce to hand n copuonayhae amgl utna/bordas

c a secko lsrapoa prad golira sod
caa ssro rderoc beolow sasfosa.
darre fboun shora
oicROs co
Ca e
gradad daprdirg on Nohinahar Mitokgic. suo
9 n d dapardura on ubula fosroaio
(D nuaclos plaonmosphuono
 Gyoda. (Loctl diloerlialad (o)
*umos call
Ponung pomanont bubula
*Sa vound N, miouc igwron rae
Cade IN (mobmatoly dffoxcolialad Ca)
umos call Povro t u t e
d h u sold clubars or sinoa i t t o i a eads
*shou 3 a a l s dagra op nudaas plasmosphum j ana ubu

Cnodo tl CFoody diffaronualo Ca)

+nasio os sdid ehaats of c o
anlaged ivagabar n
ER Ane, HER a-ve
o m ua to fooxg diPP
mat ae u l diPP Co
HER + e a
+most a_peody dp
speciihc roor ehougica podhesr san
+aso i h DCIS

ER-VCHER &-ro Ca_

poo di
easamsba pushuq bordass t racooic canbes
NVASIVE oBLAR CARCINOM
bialelic lops of enprerbion o coH qa tot apuad Ecodhn
CoROSS
palpobla. rrons
gaates ioucenabalarassaliy
cojcROS oPY
L Loose ard po drenure tumr calln>
Srroll ca utb oval ourd n ¢ srall nucod
aaronge un s r Foe CTndiao kh patabrb)
cenmod
signot ara calo aro

tubule Poson bsane

ET STASIS ni nae
bant.si 2e paroom 7 etrop aitorauu) i me

IT
 PRoONOSsTIL PREDICTIVE FeCTORs

MAJOR FACTORS

INSIT VRSUS hvAsiveg ceRLINOr9A

adaguaaly bmalad Ocls ara cuna
aDiSTANT METASTASEs
Lcue v unlikal

KumP_ NOD mETnSTDSES

stakun of a inn_io mposont progno»tk Faos

a o bas laol indrad ios 4 n
veselo b r a a Cadorass to fu
ymprati matauon
calad a sandra rodo)-enam uad fov
macoroehotanen 02e
apandung on ie 0
k o mebasbaoa
oikro
-
ae
uthat mebaa h a a lous sunnurad
lumos siz2- 4icm size
io Q0 casen
a n o t s o skD ov stalata
Loca adrancad dineone-
mapchehaa bad pro
Tplamron abona cascanee
b r o D eyhara
ski Hhickenna Odarsmnad mphaus
Faad'ovaraa -duo ti Pdara
cacuba pocuziBocagaFRmphati

doraunge - poo piorun

mINOR FACTORS KERaA

Subtype a p e s sudo oeR
derula
a Spei hiltogebp af)
ram histolo
qic sare
3 Hiohological qrade tvstina
-

oo a e
datechoo
chco

bu ouhtong
ridi haman
7Pdileaie aa- etn.
dunslug
eproersad by pogaso
OF pocaunn
Ca-t proi ok
-

poo
SR xER a te
ER- PR)
Progntorora vocap (ER
S EEskoen
PR +e opord ts osmool
raniplalino
R
mov lke eopard, to charn ottorapy
eR PR -ve
 FIOROADENOTOB
* a s coromon banugn burgod
aD 30 y
Palpabe oaluy maabla man Lalne plt
GROSS
sure !mutpla
Sunibat asumiba Tes
ual
spheita) rodaulap-
moun
bnaadt
moable
-fnaaly
bbemny,gstanuna,qirau d and
c t sectioo
hscyute
antain slit i k a spate
Sie- Cm duamaos

CRDSCO CT
dure ike shnucluroo Abvauo
mabane
iin
sknuduseoa
bJuct ka
branehurq
- dulo urd ov elahgaid. Prarn dauba u
-
ephaliuro onunq ductarqa
oaputhaliuro
i delcote. ,calabs
stronra
Hboun Cg seorra consituh o of ebrona,
CLA SSIEKOTJO
Penicaraliuulas
-
ducto u b paant unnoan
rouur ov orol lardo
USEoCoroateby -compraosad ard dichosad duos
oagunad ap
-CT ioho arolubr sea.e
Horcorn inaucad crarg
putalsal srangep-?Jardn siza. T dua ts lacolibr a drarg

9lerorva
dhange-srora bum tbrasn enoel
hyebnu2ac un dddas uarran ftas
Rocanaicalar acaralh eu
Du p
Sys wpe
Deluoic
kowA
Cor

o f u
moRPHOOnICA VeRIBNTS OF AcEorne
Tubuos adaoma - uall csannunbad turom
)actatirq adaroma - acaini uiab sacoratory a c n
danng Pognanuu ( enctoJueo
Juvenule fboadoroma ean in oddsean zurl

YNEComASTI1n
enlaaamen of ala. braas duuathupardrophu
and huposapa o arduur ard taral coanparanb
ETIOLOCY
dua uibalona- b ezdogan urd androgas
as grs-dua b hosrronal chasnger dng plbast
a a x yaaas due Hpars eptanus- iseranohomora
actha umos
loorodng
Klianaltax synda
TAiopomi e

u l casurnnCsed
s oval dis shape uf aadi
rans consistanu
mCROSLoPY
lacts uiad by mubilaanaoumnar u t o d a d

duct suss b dana collagenoun CT stroma

CLiMC9L FCATUNSS
.nil/bia
Camterad balow nupple