Professional Documents
Culture Documents
Fabrication and Self-Assembly of Nanobiomaterials. Applications of Nanobiomaterials Volume 1 1st Edition Grumezescu
Fabrication and Self-Assembly of Nanobiomaterials. Applications of Nanobiomaterials Volume 1 1st Edition Grumezescu
Nanobiomaterials. Applications of
Nanobiomaterials Volume 1 1st Edition
Grumezescu
Visit to download the full and correct content document:
https://textbookfull.com/product/fabrication-and-self-assembly-of-nanobiomaterials-ap
plications-of-nanobiomaterials-volume-1-1st-edition-grumezescu/
More products digital (pdf, epub, mobi) instant
download maybe you interests ...
https://textbookfull.com/product/engineering-of-nanobiomaterials-
applications-of-nanobiomaterials-volume-2-1st-edition-grumezescu/
https://textbookfull.com/product/surface-chemistry-of-
nanobiomaterials-applications-of-nanobiomaterials-volume-3-1st-
edition-grumezescu/
https://textbookfull.com/product/nanobiomaterials-in-cancer-
therapy-applications-of-nanobiomaterials-volume-7-1st-edition-
grumezescu/
https://textbookfull.com/product/nanobiomaterials-in-
antimicrobial-therapy-applications-of-nanobiomaterials-
volume-6-1st-edition-grumezescu/
Nanobiomaterials in Hard Tissue Engineering.
Applications of Nanobiomaterials Volume 4 1st Edition
Grumezescu
https://textbookfull.com/product/nanobiomaterials-in-hard-tissue-
engineering-applications-of-nanobiomaterials-volume-4-1st-
edition-grumezescu/
https://textbookfull.com/product/nanobiomaterials-in-soft-tissue-
engineering-applications-of-nanobiomaterials-volume-5-1st-
edition-grumezescu/
https://textbookfull.com/product/nanobiomaterials-nanostructured-
materials-for-biomedical-applications-narayan/
https://textbookfull.com/product/applications-of-biophotonics-
and-nanobiomaterials-in-biomedical-engineering-1st-edition-
mohammad-e-khosroshahi/
https://textbookfull.com/product/self-determination-the-ethics-
of-action-volume-1-1st-edition-thomas-pink/
Fabrication and Self-
Assembly of
Nanobiomaterials
Applications of
Nanobiomaterials
Fabrication and Self-
Assembly of
Nanobiomaterials
Applications of
Nanobiomaterials
Edited by
Alexandru Mihai Grumezescu
Department of Science and Engineering of Oxide Materials and
Nanomaterials, Faculty of Applied Chemistry and Materials Science,
University Politehnica of Bucharest, Romania
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience
broaden our understanding, changes in research methods, professional practices, or medical treatment
may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating
and using any information, methods, compounds, or experiments described herein. In using such
information or methods they should be mindful of their own safety and the safety of others, including
parties for whom they have a professional responsibility.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors,
assume any liability for any injury and/or damage to persons or property as a matter of products
liability, negligence or otherwise, or from any use or operation of any methods, products,
instructions, or ideas contained in the material herein.
ISBN: 978-0-323-41533-0
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library.
Library of Congress Cataloging-in-Publication Data
A catalog record for this book is available from the Library of Congress.
Marcin Banach
Institute of Chemistry and Inorganic Technology, Tadeusz Kościuszko Cracow
University of Technology, Cracow, Poland
Birendra K. Bindhani
School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India
Alexis Catala
Department of Physics and Astronomy, University of Texas at San Antonio, San
Antonio, TX, USA
Daqin Chen
College of Materials and Environmental Engineering, Hangzhou Dianzi
University, Hangzhou, P.R. China; State Key Laboratory of Structural
Chemistry, Fujian Institute of Research on the Structure of Matter, CAS,
Fuzhou, P.R. China
Jiafu Chen
Department of Chemical Engineering, Ryerson University, Toronto, ON, Canada
Mansi Chitkara
Nanomaterials Research Laboratories, Chitkara University, Punjab, India
Yaser Dahman
Department of Chemical Engineering, Ryerson University, Toronto, ON, Canada
Subash Das
Formulation and Development Product Unit, Kemwell Biopharma Pvt Ltd,
Bangalore, India
Sonia Dhiman
Chitkara college of Pharmacy, Chitkara University, Punjab, India
Mingye Ding
College of Materials and Environmental Engineering, Hangzhou Dianzi
University, Hangzhou, P.R. China
Ganesh Elango
Chemistry of Heterocycles & Natural Product Research Laboratory, Organic
Chemistry Division, School of Advanced Sciences, VIT University, Vellore, Tamil
Nadu, India
Babita Garg
University Institute of Pharmaceutical Sciences, UGC Centre of Advanced
Studies, Punjab University, Chandigarh, India
xv
xvi List of contributors
Randolph D. Glickman
Department of Physics and Astronomy, University of Texas at San Antonio, San
Antonio, TX, USA; Department of Ophthalmology, University of Texas Health
Science Center at San Antonio, San Antonio, TX, USA
Petro Petrovych Gorbyk
Nanomaterials Department, Chuiko Institute of Surface Chemistry of National
Academy of Sciences of Ukraine, Kiev, Ukraine
Ibrahim A. Hassounah
USTAR BioInnovation Center, Utah State University, Logan, UT, USA
Amanda G. Hudson
Department of Chemistry, Virginia Polytechnic Institute and State University,
Blacksburg, VA, USA
Bethany R. Hughes
Department of Chemical Engineering, Ryerson University, Toronto, ON, Canada
Michael Ioelovich
Designer Energy Ltd, Rehovot, Israel
Atul Jain
UGC Centre of Excellence in Applications of Nanomaterials, Nanoparticles &
Nanocomposites (Biomedical Sciences), Punjab University, Chandigarh, India
Hoda Javaheri
Department of Chemical Engineering, Ryerson University, Toronto, ON, Canada
Padan K. Jena
Department of Botany, Ravenshaw University, Cuttack, Odisha, India
Zhenguo Ji
College of Materials and Environmental Engineering, Hangzhou Dianzi
University, Hangzhou, P.R. China
Manish Jindal
Chitkara college of Pharmacy, Chitkara University, Punjab, India
Eugene G. Joseph
Institute for Critical Technology and Applied Sciences (ICTAS), Virginia
Polytechnic Institute and State University, Blacksburg, VA, USA; Nanoscale
Characterization and Fabrication Laboratory (NCFL), Virginia Polytechnic
Institute and State University, Blacksburg, VA, USA
Anjali Joshi
Centre for Nanoscience and Nanotechnology, U.I.E.A.S.T, Punjab University,
Chandigarh, India
List of contributors xvii
Om Prakash Katare
University Institute of Pharmaceutical Sciences, UGC Centre of Advanced
Studies, Punjab University, Chandigarh, India
Ranjot Kaur
UGC Centre of Excellence in Applications of Nanomaterials, Nanoparticles &
Nanocomposites (Biomedical Sciences), Punjab University, Chandigarh, India
Gade C. Kimsawatde
Department of Biomed Sciences and Pathobiology (DBSP), Virginia
Polytechnic Institute and State University, Blacksburg, VA, USA
Rajendra Kumar
UGC Centre of Excellence in Applications of Nanomaterials, Nanoparticles &
Nanocomposites (Biomedical Sciences), Punjab University, Chandigarh, India
Leonid Borysovych Lerman
Department of Theory of Nanostructured Systems, Chuiko Institute of Surface
Chemistry of National Academy of Sciences of Ukraine, Kiev, Ukraine
Xiaojuan Liang
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on
the Structure of Matter, CAS, Fuzhou, P.R. China
Greg Maguire
The SRM Living Foundry and BioRegenerative Sciences, Inc., San Diego, CA,
USA
Roop L. Mahajan
Institute for Critical Technology and Applied Sciences (ICTAS), Virginia
Polytechnic Institute and State University, Blacksburg, VA, USA
Saher Maswadi
Department of Electrical Engineering, University of Texas at San Antonio, San
Antonio, TX, USA
Kelly L. Nash
Department of Physics and Astronomy, University of Texas at San Antonio, San
Antonio, TX, USA
Umesh K. Parida
School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India
Alla Leonidivna Petranovska
Nanomaterials Department, Chuiko Institute of Surface Chemistry of National
Academy of Sciences of Ukraine, Kiev, Ukraine
Jolanta Pulit-Prociak
Institute of Chemistry and Inorganic Technology, Tadeusz Kościuszko Cracow
University of Technology, Cracow, Poland
xviii List of contributors
Melinda Varga
Department of Electrical Engineering and Information Technology, Technische
Universität Dresden, Dresden, Germany
Gaurav Verma
Centre for Nanoscience and Nanotechnology, U.I.E.A.S.T, Punjab University,
Chandigarh, India; Dr SS Bhatnagar University Institute of Chemical
Engineering & Technology, Punjab University, Chandigarh, India; Department
of Chemical Engineering, Massachusetts Institute of Technology, Cambridge,
MA, USA
Zhongyi Wan
College of Materials and Environmental Engineering, Hangzhou Dianzi
University, Hangzhou, P.R. China
Weidong Xiang
College of Chemistry and Materials Engineering, Wenzhou University,
Wenzhou, P.R. China
Zannatul Yasmin
Department of Physics and Astronomy, University of Texas at San Antonio, San
Antonio, TX, USA
Jiasong Zhong
College of Materials and Environmental Engineering, Hangzhou Dianzi
University, Hangzhou, P.R. China
Yang Zhou
College of Materials and Environmental Engineering, Hangzhou Dianzi
University, Hangzhou, P.R. China
Preface of the series
The era of nanosized materials is now considered the center of the evolution of
future tools and emerging technologies with wide applications in industry,
research, health, and beyond. Despite recent scientific progress, biological appli-
cations of nanomaterials are far from being depleted and current knowledge is
limited by the poor access to significant data, but also by widespread and usually
unfounded speculation. Although exhaustive, the current literature is difficult to
reach and understand because of the specificity and strict focuses of researchers
investigating different applications of nanomaterials.
In this context, the scientific series entitled “Applications of
Nanobiomaterials” was motivated by the desire of the Editor, Alexandru Mihai
Grumezescu, and others to bring together comprehensive, up-to-date and relevant
findings on the field of biological applications of nanostructure materials, to pro-
mote the knowledge and expand our vision regarding future perspectives. Even
though the approached domain is quite specific and research-oriented, this multi-
volume set is easily intelligible for a wide audience including: under-graduate and
post-graduate students, engineers, researchers, academic staff, pharmaceutical
companies, biomedical sector, and industrial biotechnologies. However, some
basic knowledge of the field of materials science (nanobiomaterials, pharmaceuti-
cal industry, products for medicinal treatments, nanoarchitectonics for delivery of
biological active molecules and release, bone implants and stomatology) and
engineering is a requisite for understanding technical aspects.
The selected authors of each chapter are outstanding specialists in the field of
nanobiomaterials, who have made impressive contributions in a specific area of
research or applied area within the scope of this book.
Each of the 11 volumes of the series contains 15 chapters, addressing the most
relevant and recent matters on the field of the volume.
The first volume, Fabrication and Self-Assembly of Nanobiomaterials, intro-
duces the reader to the amazing field of nanostructured materials and offers inter-
esting information regarding the fabrication and assembly of these nanosized
structures. In Volume II, entitled Engineering of Nanobiomaterials, readers can
easily find the most commonly investigated methods and approaches for obtaining
tailored nanomaterials for a particular application, especially those with a great
deal of significance in the biomedical field. In the following step, readers will dis-
cover the importance and the ways of modifying the surface of nanostructured
materials to obtain bioactive materials, by reading Volume III, Surface Chemistry
of Nanobiomaterials. Starting with Volume IV Nanobiomaterials in Hard Tissue
Engineering and Volume V Nanobiomaterials in Soft Tissue Engineering the bio-
medical applications of engineered nanaomaterials are revealed and discussed,
focusing on one of the most impacted fields, tissue engineering. Volume VI,
Nanobiomaterials in Antimicrobial Therapy, highlights the potential of different
nanostructured materials to be utilized in the development of novel efficient
xxi
xxii Preface of the series
Ecaterina Andronescu
Department of Science and Engineering of Oxide Materials and Nanomaterials,
Faculty of Applied Chemistry and Materials Science,
University Politehnica of Bucharest, Bucharest, Romania
Fabrication and self-assembly of
nanobiomaterials: applications of
nanobiomaterials
xxiii
xxiv Fabrication and self-assembly of nanobiomaterials
ABOUT VOLUME I
The first volume provides recent and applicative knowledge regarding the
fabrication and self-assembly of nanobiomaterials for different biomedical
applications. In this volume various and detailed fabrication routes for specific
applications are described. Current applications of nanotechnology in the biomed-
ical field developed to answer the high demand for innovative approaches for
diagnosis, exploratory, and therapeutic needs motivates the purpose of this
volume to summarize current research findings concerning the fabrication and
self-assembly of nanobiomaterials. Volume I contains 15 chapters, prepared by
outstanding international researchers from the United States of America, Mexico,
Portugal, the United Kingdom, Czech Republic, Russia, Turkey, Iran, Australia,
India, and China.
In Chapter 1, Synthesis, characterization, and applications of nanoparticles,
Dahman et al. present an up-to-date overview regarding the rapid development of
the fabrication of nanoparticles over the last two decades that has driven tremen-
dous advances on the field.
Joshi et al., in Chapter 2, Self-assembled nanostructure: preparation and
applications, discuss about the fabrication of nanostructures from biological
building blocks. The self-assembly of such nanostructures is a spontaneous
process by which molecules/nanophase entities will materialize into organized
aggregates. Many biomolecules, such as proteins and peptides, can interact and
self-assemble into highly ordered supramolecular architectures including nano-
tubes, nanofibrils, nanowires, spherical vesicles, and hybrids, the subsequent
improvement of their properties and their possible applications.
Chapter 3, Self-assembly of nanobiomaterials, prepared by Varga et al., offers
a recent review regarding the surface-layer proteins (S-layers) that represent a
unique self-assembling system. Their remarkable property of self-assembling and
their repetitive physicochemical properties down to the nanometer scale led to
various applications in the fields of bio- and nanotechnology. Chapter 3 focuses
on the basic principles and self-assembly properties of the S-layer protein of
Sporosarcina ureae.
In Chapter 4, Self-nanoemulsifying systems for oral bioavailability enhancement:
recent paradigms, Bhupinder Singh et al. reveal the current approaches regarding the
self-nanoemulsifying drug delivery systems (SNEDDS) that are known to possess
Fabrication and self-assembly of nanobiomaterials xxv
UC nanoparticles. In the end, this chapter points out the challenges and perspec-
tives of the developing impurity-doping strategy.
Ioelovich et al., in Chapter 9, Nanocellulose—fabrication, structure, proper-
ties, and application in the area of care and cure, discuss methods of preparation,
structure, properties, and applications of various kinds of nanocellulose. The
authors demonstrate that after the introduction of specific functional groups, the
cellulose nanocarriers can be obtained and used to joining various therapeutically
active substances (proteolytic enzymes, amino acids, antioxidants, hemostatic
drugs, etc.), which expand application areas of nanocellulose in the care and cure
branches.
Gorbyk et al., in Chapter 10, Magnetosensitive nanocomposites with hierarchi-
cal nanoarchitecture as biomedical nanorobots: synthesis, properties, and appli-
cation, present new concepts of the chemical design of magnetically sensitive
nanocomposites with multilevel hierarchical architecture and functions of medico-
biological nanorobots in: recognition of microbiological objects in biological
media; targeted drug delivery into target cells and organs, and deposition; com-
plex treatment with chemo-, immuno-, radio-, hyperthermic methods and real-
time diagnostics; adsorption of residual cell debris and removing them from the
body with the help of an external magnetic field.
Hassounah et al., in Chapter 11, Designing and testing single tablet for tuber-
culosis treatment through electrospinning, reveal the current knowledge about
tuberculosis drugs (pyrazinamide, isoniazid, clarithromycin, and streptomycin)
loaded on poly(ε-caprolactone), poly(ethylene oxide), and poly(vinyl alcohol)
nanofibers to design a single tablet suitable for HIV patients.
Banach et al., in Chapter 12, Synthesis, characteristics, and biocidal activity
of silver nanoparticles, report an up-to-date overview about the fabrication and
applications of silver nanoparticles in the biomedical field.
Singh et al., in Chapter 13, Nanobiomaterials: applications in biomedicine
and biotechnology, review the fabrication of nanoscale biomaterials for medical
and biotechnological applications. Nanoscale molecular tools in nanobiomedicine
are used for diagnostic purposes and improvement of human health. Pivotal stud-
ies, both nonclinical and clinical, in the aspects of safety and tolerance are the
necessity of recent times in order to formulate their potential commercial
application.
Hughes et al., in Chapter 14, Control, design and understanding of molecular
self-assembly, discuss about self-assemblies. Essentially, the nanostructure builds
itself starting with construction of the individual building blocks, which have the
final structure encoded into their properties, and ending with a complete
structure. Nanoengineering for biomedical applications is essential to the
development of tissue engineering and regenerative medicine because the size of
most biological functional units is in the order of nanometers. For example,
proteins, nucleic acids, viruses, and cellular membranes possess highly precise
arrangements on the nanoscale derived from the molecular-level structure.
Fabrication and self-assembly of nanobiomaterials xxvii
Synthesis, characterization
and applications of
nanoparticles 1
Jiafu Chen, Hoda Javaheri, Basel Al-Chikh Sulaiman and Yaser Dahman
Department of Chemical Engineering, Ryerson University, Toronto, ON, Canada
1.1 INTRODUCTION
The terms nanotechnology, nanostructure, nanoscience, and nanoparticles have
recently been used widely in scientific and engineering literatures. It was found
that nanostructured materials are very applicable and useful in regenerative medi-
cine to repair and augment damaged or lost organs or tissues. This can be explained
by their ability to travel through the human body. Furthermore, other applications
include their applications in biological detection, controlled drug delivery, low-
threshold laser, optical filters, and also sensors, among others (Fredy, 2008).
FIGURE 1.11
The net interaction energy is derived from the resulting combination of repulsive and
attractive energy (Yu et al., 2008).
*****
Ida Aalberg ei ole syntynyt 3/XII 1858 vaan 4/XII 1857, kuten
Janakkalan kirkonarkistossa oleva kastekirja todistaa. Siihen aikaan
Ahlbergit asuivat Leppäkosken kartanossa, joka siis oli Ida Aalbergin
syntymäpaikka. Kummien joukossa on myöskin ollut varatuomari
Spåre vaimonsa Napoleone Emilia Catharina Lovisa Spåren kanssa,
ja luultavasti kartanonrouvan kunniaksi lapselle annettiin toiseksi
nimeksi Emilia. Ida Aalbergin sanotaan syntyneen eräässä kartanon
sivurakennuksessa, mutta kaste toimitettiin päärakennuksen salissa.
On arveltu, että lapsi oli kivulloinen ja heikko, koska kirkollinen
toimitus tapahtui jo kaksi päivää syntymisen jälkeen; sellainen
kiireellisyys näet ei ollut paikkakunnalla muuten tavallista.
II.
KOTOA POIS
*****
*****
Että taiteilijan kuvaus, niin leikillisesti kuin hän toisinaan lienee sen
antanutkin, ei ole vailla todellisuuspohjaa, todistavat ne muistelmat,
joita muilla henkilöillä on ollut Ida Aalbergin varhaisimmasta
lapsuudesta. »Korkeahenkinen ja oman arvonsa tunteva se oli jo
pienenä», on paikkakunnalla kerrottu. Äidilleen, joka huokasi: »Sinä
olet kuin lintu lennossaan, mikähän sinustakin tulee?» tytär vastasi:
»Minusta tulee friherrinna.» On muistettu hänen keppi kädessä
ajaneen pakoon kokonaisen lapsilauman, ja vanhin veli, Oskar, on
kertonut, että Ida pienenä kapuillessaan Leppäkosken korkeassa
rautatiesillassa oli pudonnut ja taittanut kätensä.
*****
Tiedot siitä, milloin tuleva suuri näyttelijätär oli ensi kerran nähnyt
teatterin, ovat jonkin verran ristiriitaisia. Nähtävästi hänen omien
puheittensa perusteella on kirjoitettu, ettei hän ole nähnyt
näyteltävän ainakaan ennen vuotta 1874, jolloin hän itse sai näytellä
ja pääsi myöskin katsomaan jotakin Suomalaisen teatterin esitystä
Hämeenlinnaan. Suomalaisen teatterin historiassa on sentään
poikkeava tiedonanto: siinä sanotaan, että Ida oli taivuttanut äitinsä
lähtemään kanssaan Hämeenlinnaan toukokuussa 1873 katsomaan
»Viuluniekkaa», joka oli teatterin avajaisnäytäntönä 4/V ja josta
paikallinen sanomalehti kirjoittaa m.m.:
Rakas siskoseni!
veljekses Oskar.