Clinical Parasitology

Chapter 6: Select Sporozoa: Plasmodium and Babesia

Quick Quiz & Test Your Knowledge!

6-1. The infective stage of Plasmodium is(are) the: 6-9. Which of the following is considered an
(Objective 6-6) antimalarial medication? (Objective 6-9A)
A. Merozoites A. Amoxicillin
B. Oocyst B. Erythromycin
C. Sporozoites C. Chloroquine
D. Gametocytes D. Dicyclomine

6-2. The best time to collect blood for Plasmodium 6-10. Which morphologic form is not typically seen in
parasites is: (Objective 6-10) infections of P. malariae? (Objective 6-7B)
A. Between paroxysms A. Mature schizont
B. During paroxysms B. Ring form
C. Morning C. Immature schizont
D. Evening D. Macrogametocyte

6-3. A paroxysm is: (Objective 6-1) 6-11. Which of the following are morphologic features
A. An allergic reaction of P. malariae? (Objective 6-12A)
B. A periodic episode characterized by fever, chills, A. Schüffner’s dots
sweats, and fatigue B. Ziemann’s dots
C. Both A and B are correct. C. Maurer’s dots
D. None of the above D. None of the above

6-4. Which morphologic characteristic may help in 6-12. Which of the following is not a prevention and
distinguishing P. vivax from P. falciparum? (Objective control measure for malaria? (Objective 6-9B)
6-11) A. Wearing the hair up
A. Hemozoin B. Following prophylactic therapy when traveling to
B. Schüffner’s dots malaria-endemic areas
C. 72-hour paroxysm C. Bed netting
D. None of the above D. Proper clothing, such as long-sleeved shirt and
long pants
6-5. P. vivax characteristically invades: (Objective 6-7A)
A. Immature RBCs 6-13. What age of red blood cell does P. falciparum
B. Senescent RBCs typically invade? (Objective 6-7A)
C. All RBCs A. Mature red blood cells
D. Lymphocytes B. Immature red blood cells
C. All red blood cells, regardless of age
6-6. The incubation period for P. vivax is generally: D. Does not invade red blood cells
(Objective 6-8)
A. 6 to 8 days 6-14. P. falciparum is commonly found in the United
B. 7 to 10 days States. (Objective 6-2)
C. 12 to 24 days A. True
D. 10 to 17 days B. False

6-7. Which morphologic form would be the best choice 6-15. Black water fever can be described by which of
for distinguishing between P. vivax and P. ovale? the following: (Objective 6-1)
(Objective 6-11) A. Marked hemoglobinuria
A. Mature schizont B. Kidney involvement in P. falciparum infections
B. Ring form C. Caused by P. falciparum–induced red blood cell
C. Early trophozoite destruction
D. Immature schizont D. All of the above

6-8. In which geographic regions would the 6-16. Humans are an accidental host of Babesia
laboratorian most likely suspect P. ovale as the species. (Objective 6-6)
infecting agent? (Objective 6-2) A. True
A. Tropical Africa B. False
B. Asia
C. South America 6-17. The specimen of choice for the recovery of
D. All of the above Babesia is: (Objective 6-10)
A. Tissue
B. Cerebral spinal fluid (CSF)
C. Stool
D. Blood
 Clinical Parasitology
Chapter 6: Select Sporozoa: Plasmodium and Babesia
Quick Quiz & Test Your Knowledge!

6-18. Babesiosis is characterized by all the following 6-4. Which of the following is a self-limiting infection
except: (Objective 6-8) characterized by a gradual onset of headache, chills,
A. Trophozoites resembling the ring form seen in sweating, and fatigue that demonstrates no
Plasmodium infections periodicity? (Objective 6-8)
B. A mild to severe hemolytic anemia A. Ehrlichia phagocytophila
C. Fever periodicity B. Babesia microti
D. None of the above C. Plasmodium vivax
D. Plasmodium ovale
6-19. Which of the following are laboratory diagnostic
procedures is recommended for specifically 6-5. Giemsa-stained blood smears demonstrate
identifying T. microti? (Objective 6-10) normal-sized red blood cells containing ring form
A. Thick and thin blood films trophozoites in pairs and tetrads, without pigment or
B. Serologic testing stippling. Which parasite listed best fits this
C. PCR techniques description? (Objective 6-12C)
D. Both B and C are correct. A. Babesia divergens
E. None of the above B. Plasmodium falciparum
C. Plasmodium vivax
6-20. Which of the following is not a location known D. Plasmodium malariae
for infection by T. microti? (Objective 6-2)
A. California 6-6. Sexual reproduction of Babesia species takes
B. North Carolina place in the: (Objective 6-6)
C. Mexico A. Human gut
D. Nantucket B. Red blood cells
C. Tick
6-21. For which patient would babesiosis be more D. Parenchymal cells of the liver
severe? (Objective 6-8)
A. The splenectomized 6-7. Which species of Plasmodium is characterized by
B. The patient with Babesia divergens a rosette arrangement of merozoites and the presence
C. Older adults of Schüffner’s dots in the red blood cells? (Objective
D. All of the above 6-12C)
A. Plasmodium vivax
B. Plasmodium ovale
C. Plasmodium falciparum
6-1. The infective stage of the Plasmodium parasite D. Plasmodium malariae
and the Babesia parasite for humans is the: (Objective
6-6) 6-8. Babesia spp. undergo an exoerythrocytic
A. Merozoite cycle. (Objective 6-6)
B. Trophozoite A. True
C. Gametocyte B. False
D. Sporozoite
6-9. Ziemann’s dots, band form trophozoites, and
6-2. What is the name of the dormant parasite form 72-hour periodicity of paroxysms is indicative of
found in patients with Plasmodium ovale and infection with which Plasmodium species? (Objective
Plasmodium vivax infections? (Objective 6-1) 6-8)
A. Trophozoites A. Plasmodium vivax
B. Sporozoites B. Plasmodium ovale
C. Hypnozoites C. Plasmodium falciparum
D. Gametocytes D. Plasmodium malariae

6-3. The species of mosquito most commonly known 6-10. Which of the following would be an advised drug
to serve as a vector for the genus Plasmodium is: therapy for an uncomplicated case of babesiosis?
(Objective 6-6) (Objective 6-9A)
A. Ixodes A. Clindamycin-quinine
B. Anopheles B. Atovaquone-proguanil
C. Culex C. Penicillin-aspirin
D. Glossina D. Erythromycin-chloroquine