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Textbook of
Endocrine Surgery
Third Edition

Illustration by Emilie G Clark


Textbook of
Endocrine Surgery
Third Edition

Editors
Orlo H Clark MD
Professor Emeritus of Surgery
Department of Surgery
Division of General Surgery
University of California, San Francisco
San Francisco, California, USA

Quan-Yang Duh MD Electron Kebebew MD


Professor Chief, Senior Investigator
Department of Surgery Endocrine Oncology Branch
University of California, San Francisco National Cancer Institute
San Francisco, California, USA Bethesda, Maryland, USA

Jessica E Gosnell MD Wen T Shen MD MA


Assistant Professor of Surgery Associate Professor of Clinical Surgery
Department of Surgery Department of Surgery
Division of General Surgery Division of General Surgery
University of California, San Francisco University of California, San Francisco
San Francisco, California, USA Medical Center at Mount Zion
San Francisco, California, USA

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Textbook of Endocrine Surgery


First Edition: 1997 (Published by Saunders)
Second Edition: 2005 (Published by Saunders)
Third Edition: 2016
ISBN 978-93-5152-806-7
Printed at:
Dedication
The third edition of our Textbook of Endocrine Surgery is
dedicated to our families, endocrine surgical fellows,
residents, students, endocrinologists, and our patients.
Contributors

Shabirhusain S Abadin MD MPH Jon D Armstrong MD Anthony C Boganey MD


Assistant Professor Service de Chirurgie Endocrinienne Endocrine Surgeon
Department of General Surgery et d'Anatomopathologie Naval Medical Center San Diego
John H. Stroger, Jr. Hospital of Cook Lille University Hospital San Diego, California, USA
County and Rush University Hôpital Huriez
Chicago, Illinois, USA Lille Cedex, France Michael Sean Boger
Assistant Professor
Gaurav Agarwal Sylvia L Asa MD PhD Department of Medicine
Professor Pathologist-in-Chief Division of Infectious Diseases
Department of Endocrine and University Health Network Medical University of South Carolina
Breast Surgery Professor Charleston, South Carolina, USA
Sanjay Gandhi Postgraduate Institute of Department of Laboratory
Medical Sciences, Lucknow Medicine and Pathobiology Myriem Boufraqech PhD
Lucknow, Uttar Pradesh, India University of Toronto Post-doctoral Fellow
Toronto, Ontario, Canada Endocrine Oncology Branch
Göran Åkerström MD PhD National Center Institute
Professor Emeritus Ahmet Ayav MD PhD National Institutes of Health
Institution of Surgical Sciences Department of Digestive, Bethesda, Maryland
Department of Surgery Endocrine, HPB and Oncological Surgery
Uppsala University University Hospital of Nancy
Michael Bouvet MD
Uppsala, Sweden Nancy, France
Professor
Anthony Beaulieu MD Department of Surgery
Maha Al-Fehaily MD Department of Endocrine Surgery University of California, San Diego
Consultant, Breast and Endocrine Surgeon University Hospital of Poitiers San Diego, California, USA
Department of Surgery Poitiers, France
King Faisal Specialist Hospital and Nori L Bradley MD
Research Center Rocco Bellantone MD Resident
Assistant Professor Professor General Surgery
Alfaisal University Department of Surgery University of British Columbia
Riyadh, Saudi Arabia Head of Endocrine and Vancouver, British Columbia, Canada
Metabolic Surgery
Saif Al-Sobhi MD Catholic University of Sacred Heart Michael Brauckhoff MD
Consultant Rome, Italy Department of General,
Director Fellowship Training Program Visceral and Vascular Surgery
Department of Surgery, Riyadh Toni Beninato MD University Hospital Halle
King Faisal University (MBBS) Chief Resident Department of Surgery
Riyadh, Saudi Arabia Department of Surgery Haukeland University Hospital
University of Southern California NewYork-Presbyterian Hospital— Department of Surgical Sciences
Los Angeles, California, USA Weill Cornell Medical College University of Bergen
New York, New York, USA Bergen, Norway
Peter Angelos MD PhD
Professor and Chief of Endocrine Surgery Daniel D Bikle MD PhD Laurent Bresler MD
Department of Surgery Professor University of Lorraine
University of Chicago Department of Medicine and Dermatology Department of Digestive,
Pritzker School of Medicine University of California, San Francisco Hepatobiliary and Endocrine Surgery
Chicago, Illinois, USA San Francisco, California, USA Vandoeuvre-les-Nancy, France
viii Textbook of Endocrine Surgery

Laurent Brunaud MD Ryaz Chagpar MSc MD FRCSC Robin M Cisco MD


Professor of Surgery Endocrine Surgery Fellow Department of Surgery
Department of Digestive, Hepatobiliary Department of Endocrine Surgery El Camino Hospital
Endocrine and Oncologic Surgery Cleveland Clinic Mountain View, California, USA
CHU Nancy Brabois Cleveland, Ohio, USA
University of Lorraine Orlo H Clark MD
Vandoeuvre-les-Nancy Anthony Hung Chau MD Professor Emeritus of Surgery
France General Surgery Resident Department of Surgery
Department of General Surgery Division of General Surgery
Maria E Cabanillas MD San Joaquin General Hospital University of California, San Francisco
French Camp, California, USA San Francisco, California, USA
Associate Professor
Department of Endocrine Neoplasia and
Wei Keat Cheah MBBS FRACS FAMS FACS Roderick Clifton-Bligh MD
Hormonal Disorders
Associate Professor Associate Professor
The University of Texas MD Anderson
Department of Surgery Medicine, Northern Clinical School
Cancer Center
Ng Teng Fong General Hospital Kolling Institute of Medical Research
Houston, Texas, USA
Jurong Health Services, Singapore The University of Sydney
Sydney, Australia
Glenda G Callender MD
Donald M Cheatem MD PhD
Assistant Professor Resident Alan P Dackiw MD PhD
Department of Surgery Department of Surgery Professor
Yale University University of Illinois Department of Surgery
School of Medicine Chicago, Illinois, USA University of Texas Southwestern
New Haven, Connecticut, USA
Dallas, Texas, USA
Harn-Shen Chen MD PhD
Michael J Campbell MD Professor
Leigh W Delbridge MD FRACS
Assistant Professor Division of Endocrinology and Metabolism
Emeritus Professor
Department of Surgery Department of Medicine
Department of Surgery
University of California Davis Taipei Veterans General Hospital
University of Sydney
Sacramento, California, USA Taipei, Taiwan
Sydney, New South Wales, Australia

Nadine R Caron MD MPH Herbert Chen MD


Professor and Chairmen Michael J Demeure MD MBA
Assistant Professor
Division of General Surgery Professor
Department of Surgery
Department of Surgery Integrated Cancer Genomics
University of British Columbia
University of Wisconsin Translation Genomics Research Institute
Northern Medical Program
Madison, Wisconsin, USA Phoenix, Arizona, USA
Prince George, British Columbia
Canada
Kathleen K Christians MD Michele Diana MD
Department of Surgery Director of the Research Unit on
Azadeh A Carr MD
The Medical College of Wisconsin Endo-Laparoscopic Procedures
Assistant Professor Milwaukee, Wisconsin, USA IHU-Strasbourg Institute for
Department of Surgery Minimally Invasive
Medical College of Wisconsin Image-Guided Surgery
Woong Youn Chung MD PhD
Milwaukee, Wisconsin, USA Strasbourg, France
Department of Surgery
Open NBI Convergence Technology
Sally E Carty MD Research Laboratory Gerard M Doherty MD
Professor of Surgery Severance Hospital Utley Professor and Chair
Department of Surgery Yonsei Cancer Center Department of Surgery
University of Pittsburgh Yonsei University College of Medicine Boston University
Pittsburgh, Pennsylvania, USA Seoul, Republic of Korea Boston, Massachusetts, USA
Contributors ix
Gianluca Donatini MD Ryan D Eubanks DO Rebekkah W Frunzac MD PhD
Doctor Resident General Surgeon
Department of Endocrine Surgery Department of Surgery Mayo Clinic
University of Poitiers Maricopa Medical Center Rochester, Minnesota, USA
Poitiers, France Phoenix, Arizona, USA
Armando Gamboa-Dominguez MD PhD
Henning Dralle MD FRCS FACS FEBS Douglas B Evans MD Chairman
Professor of Surgery Donald C Ausman Family Foundation Department of Pathology
Department of Surgery Professor of Surgery and Chair Instituto Nacional de Ciencias Médicas y
Department of Surgery Nutrición Salvador Zubirán
University of Halle-Wittenberg
Medical College of Wisconsin Mexico City, Mexico
Germany
Milwaukee, Wisconsin, USA
Quan-Yang Duh MD Adeline Germain MD
Thomas J Fahey III MD Department of Digestive, Endocrine,
Professor Professor of Surgery and Chief
Department of Surgery HBP and Oncological Surgery
Division of Endocrine Surgery
University of California, San Francisco University Hospital of Nancy, France
Director
San Francisco, California, USA Nancy, France
Endocrine Oncology Program
Weill Cornell Medical College
Damian E Dupuy MD New York, New York, USA Maher Ghanem MD
Professor Assistant Professor
Department of Diagnostic Imaging Gennaro Favia MD Department of General Surgery
The Warren Alpert Medical Professor of Surgery Central Michigan University
School of Brown University Department of Surgery and College of Medicine
Providence, Rhode Island, USA Gastroenterological Science Saginaw, Michigan, USA
University of Padova
Cosimo Durante MD PhD Padova, Italy Peter E Goretzki MD
Assistant Professor of Internal Medicine Professor
Internal Medicine and Eric C Feliberti MD Department of Surgery
Medical Specialties Assistant Professor Lukaskrankenhaus, Neuss
University of Rome “Sapienza” Eastern Virginia Medical School Neuss, Germany
Rome, Italy Norfolk, Virginia, USA
Jessica E Gosnell MD
Erol Duren MD Sebastiano Filetti MD Assistant Professor of Surgery
Professor Internal Medicine Department of Surgery
Department of Endocrine Surgery Internal Medicine and Medical Specialties Division of General Surgery
University of Istanbul University of Rome “Sapienza” University of California, San Francisco
Istanbul, Turkey Rome, Italy San Francisco, California, USA

Mete Duren MD Abbey L Fingeret MD Clive S Grant


Professor Chief Resident Professor of Surgery
Department of Surgery
Department of Endocrine Surgery Department of Surgery
Columbia University Medical Center
University of Istanbul Mayo Clinic
New York, New York, USA
Istanbul, Turkey Rochester, New York, USA
Douglas L Fraker MD
Dina M Elaraj MD Chief, Division of Endocrine and Raymon H Grogan MD
Assistant Professor Oncologic Surgery Assistant Professor
Section of Endocrine Surgery Deputy Director Department of Surgery
Department of Surgery Clinical Services and Programs Endocrine Surgery Group
Northwestern University Feinberg Abramson Cancer Center of the University of Chicago
School of Medicine University of Pennsylvania Pritzker School of Medicine
Chicago, Illinois, USA Philadelphia, Pennsylvania, USA Chicago, Illinois, USA
x Textbook of Endocrine Surgery

Staffan Grondal MD Jean-François Henry MD FRCS Linda X Jin MD


Department of Surgery Professor of Surgery Resident in General Surgery
Karolinska Hospital Department of Endocrine Surgery Department of Surgery
Stockholm, Sweden University-Hospital La Conception Washington University in St. Louis
Marseille, France St Louis, Missouri, USA
Jeffrey P Guenette MD
Resident Miguel F Herrera MD PhD Edwin L Kaplan MD
Department of Radiology Professor of Endocrine Surgery Professor
Brigham and Women’s Hospital Department of Surgery Department of Surgery
Boston, Massachusetts, USA Instituto Nacional de la Nutrición University of Chicago
Salvador Zubiran Pritzker School of Medicine
Marlon A Guerrero MD Universidad Nacional Autónoma de Chicago, Illinois, USA
Assistant Professor México
Department of Surgery Mexico, Distrito Federal, Mexico Adem Karatas
University of Arizona Associate Professor
Tucson, Arizona, USA Jesse SL Hu FRCS Department of General Surgery and
Department of Surgery Endocrine Surgery
Ng Teng Fong General Hospital Cerrahpasa Medical School
Philip I Haigh MD MSc FRCSC FACS
Jurong Health Services Istanbul University
Surgical Oncology and Endocrine
Singapore Istanbul, Turkey
Surgery
Department of Surgery
Shih-Ming Huang Electron Kebebew MD
Kaiser Permanente
Professor Chief, Senior Investigator
Los Angeles Medical Center
Department of Surgery Endocrine Oncology Branch
Los Angeles, California, USA
National Cheng Kung University National Cancer Institute
Tainan, Taiwan Bethesda, Maryland, USA
Bertil Hamberger MD
Departments of Surgery, Maurizio Iacobone MD Rachel R Kelz MD
Clinical Chemistry and Endocrinology Professor of Surgery Associate Professor of Surgery at the
Karolinska Hospital Minimally Invasive Endocrine Hospital of the University of
Stockholm, Sweden Surgery Unit Pennsylvania
Department of Surgery, Philadelphia, Pennsylvania, USA
Jaap F Hamming MD PhD Oncology and Gastroenterology
Professor of Surgery University of Padua Christine M Kennedy BSc
Department of Surgery Padova, Italy University of British Columbia –
Leiden University Medical Center
Northern Medical Program
Leiden, The Netherlands Yasuhiro Ito MD PhD Prince George, British Columbia
Director of Clinical Trial Canada
Avital Harari MD MSc Management Center
Assistant Professor of Surgery Department of Surgery Moosa NG Khalil
Department of Surgery Kuma Hospital Clinical Associate Professor
Section of Endocrine Surgery Kobe, Japan Department of Pathology
University of California, Los Angeles University of Calgary
Los Angeles, California, USA Benjamin James MD Calgary, Alberta, Canada
General Surgeon
Per Hellman MD PhD Hershey, Pennsylvania, USA Abdul H Khan MD
Professor Assistant Professor
Institution of Surgical Sciences Zafir A Javeed BS Division of GI and Hepatology
Uppsala University MD Candidate Medical College of Wisconsin
Uppsala, Sweden California, USA Milwaukee, Wisconsin, USA
Contributors xi
Aliya A Khan MD FRCPC FACP FACE Jandee Lee MD PhD Leyre Lorente MD
Professor of Clinical Medicine Department of Surgery Endocrine Surgery Unit
Divisions of Endocrinology and Open NBI Convergence Technology Hospital del Mar
Metabolism and Geriatric Medicine Research Laboratory Barcelona, Spain
McMaster University Severance Hospital
Hamilton, Ontario, Canada Yonsei Cancer Center Kerstin Lorenz MD
Yonsei University College of Medicine Professor of Surgery
Elham Khanafshar Seoul, Republic of Korea Department of General, Visceral and
Associate Clinical Professor Vascular Surgery
Department of Pathology John I Lew MD FACS University of Halle–Wittenberg
University of California, San Francisco Associate Professor of Surgery Halle (Saale), Germany
San Francisco, California, USA Chief of Endocrine Surgery
DeWitt Daughtry Daria Maccora MD
Job Kievit MD PhD Department of Surgery Department of Surgery
Professor of Quality in Healthcare University of Miami Leonard M Miller Division of General and
Consultant Surgeon School of Medicine Endocrine Surgery
Chief, Endocrine/Head and Neck Surgery Miami, Florida, USA Università Cattolica del Sacro Cuore
Leiden University Medical Center Rome, Italy
Leiden, The Netherlands Hong-Da Lin MD
Department of Life Sciences Andreas Machens MD
National Cheng Kung University Associate Professor
Jean-Louis Kraimps MD
Tainan City , Taiwan Department of General
Professor
Visceral and Vascular Surgery
Department of Endocrine Surgery
Dimitrios A Linos MD PhD Martin Luther University Halle–
University of Poitiers
Professor of Surgery Wittenberg, Halle (Saale), Germany
Poitiers, France
Athens Medical School
Athens, Greece Lloyd A Mack MD
Anna Kundel MD Associate Professor
Assistant Professor Chienying Liu MD Department of Surgery and Oncology
Department of Endocrine Surgery Associate Clinical Professor University of Calgary
New York University Calgary, Alberta, Canada
Department of Medicine
New York, New York, USA
Division Endocrinology,
Diabetes and Metabolism Kate Madorin MD
Geeta Lal MD University of California, San Francisco College Station Medical Center
Associate Professor San Francisco, California, USA College Station, Texas, USA
Department of Surgery
University of Iowa Chung Yau Lo MD Jacques Marescaux MD FACS Hon. FRCS
Iowa City, Iowa, USA University of Hong Kong              Hon. FJSES Hon. APSA

Hong Kong Professor


Chen-Hsen Lee MD FACS IRCAD-IHU, Department of Digestive
Professor of Surgery Lutske Lodewijk MD and Endocrine Surgery
Department of Surgery Department of Surgery University of Strasbourg, France
Taipei Veterans General Hospital University Medical Center Utrecht Strasbourg, France
National Yang-Ming University Utrecht, The Netherlands
Taipei, Taiwan Aarti Mathur MD
Celestino Pio Lombardi Assistant Professor
James Lee MD Professor of Surgery Department of Surgery
Associate Professor Department of Endocrine and Division of Endocrine Surgery
Department of Surgery Metabolic Surgery The Johns Hopkins University School of
Columbia University Università Cattolica del Sacro Cuore Medicine
New York, New York, USA Rome, Italy Baltimore, Maryland, USA
xii Textbook of Endocrine Surgery

Kelly L McCoy MD FACS Michele N Minuto MD PhD Eric K Nakakura MD PhD


Assistant Professor of Surgery Assistant Professor of Surgery Associate Professor
Division of Endocrine Surgery Department of Surgical Scienes (DISC) Department of Surgery
University of Pittsburgh University of Genoa University of California
Pittsburgh, Pennsylvania, USA Genoa, Italy San Francisco, California, USA

Christopher R McHenry Gitika Nanda MS MCh


Elliot J Mitmaker MD MSc FRSCS FACS Assistant Professor
Professor Assistant Professor
Department of Surgery Department of Surgery
Department of Surgery King George Medical University
Case Western Reserve University
McGill University Lucknow, Uttar Pradesh, India
Cleveland, Ohio, USA
Montreal, Quebec, Canada
Matthew A Nehs MD
Travis J McKenzie MD
Akira Miyauchi MD PhD Instructor in Surgery
Assistant Professor of Surgery
Department of Surgery Department of Surgery
Department of Surgery
Kuma Hospital Brigham and Women’s Hospital
Mayo Clinic
Kobe, Japan Harvard Medical School
Rochester, Minnesota, USA
Boston, Massachusetts, USA
Ozgur Mete MD Jacob Moalem MD FACS Aaron B Neinstein MD
Assistant Professor Associate Professor Assistant Professor
Department of Laboratory Endocrine Surgery and Endocrinology Department of Medicine
Medicine and Pathobiology University of Rochester University of California, San Francisco
University of Toronto Rochester, New York, USA San Francisco, California, USA
Toronto, Ontario, Canada
Jeffrey F Moley MD Bruno Niederle MD
Paolo Miccoli Professor of Surgery Professor
Professor Department of Endocrine and Department of Surgery
Department of Surgical Division of General Surgery and
Oncologic Surgery
Medical Molecular and of the Critical Endocrine Surgery
Washington University School of
Area Pathology Medical University
Medicine
University of Pisa – Italy Vienna, Austria
St Louis, Missouri, USA
Pisa, Italy
Sarah Nielsen MS CGC
Jack M Monchik MD
Radu Mihai Certified Genetic Counselor
Clinical Professor of Surgery
Consultant Endocrine Surgeon Cancer Risk Program
Chief, Endocrine Surgery The Center for Clinical Cancer Genetics
Department of Endocrine Surgery
Rhode Island Hospital and Global Health
Churchill Cancer Centre
The Warren Alpert Medical School of The University of Chicago
Oxford, United Kingdom
Brown University Chicago, Illinois, USA
Providence, Rhode Island, USA
Mira Milas MD FACS
Professor of Surgery and Shiro Noguchi MD PhD
Willieford O Moses MD Chief Executive Officer
Chief of Endocrine
Resident Noguchi Thyroid Clinic and Hospital
Surgery at Banner-University
Department of Surgery Foundation
Medical Center Phoenix
University of California, San Francisco Beppu, Oita, Japan
Phoenix, Arizone, USA
San Francisco, California, USA
Yasushi Noguchi MD
Zvonimir L Milas Sapna Nagar MD Board Director
Associate Professor Department of General Surgery Executive Director of Radiology and
Department of Surgery Beaumont Health System Nuclear Medicine
Levine Cancer Institute Oakland University Noguchi Thyroid Clinic and Hospital
Carolinas Medical Center William Beaumont School of Medicine Foundation
Charlotte, North Carolina, USA Royal Oak, Michigan, USA Beppu, Oita, Japan
Contributors xiii
Jeffrey A Norton MD Jin-Woo Park MD Nancy D Perrier MD
Department of Surgery Professor Professor
Stanford University School of Medicine Department of Surgery Department of Surgical Oncology
Stanford, California, USA Chungbuk National University The University of Texas MD Anderson
Cheongju, Chungbuk Cancer Center
Patricia J Numann MD Republic of Korea Houston, Texas, USA
Lloyd S. Rogers Professor of Surgery
Emerita Robert F Parkyn FRACS Roger R Perry MD MS FACS
Department of Surgery Associate Professor Robert L. Payne Jr., Professor of Surgery
SUNY Upstate Medical University Breast and Endocrine Surgical Unit Chief, Division of Surgical Oncology
Syracuse, New York, USA The Queen Elizabeth Hospital Department of Surgery
University of Adelaide Eastern Virginia Medical School
Jennifer B Ogilvie MD FACS Adelaide, Australia Norfolk, Virginia, USA
Associate Professor
Department of Surgery Pasqual Parrilla MD Richard A Prinz MD FACS
Division of Endocrine Surgery Department of Surgery, Clinical Professor of Surgery
New York University Langone Pediatrics, Obstetrics and Department of Surgery
Medical Center Gynecology North Shore University Health System
New York, New York, USA University of Murcia Evanston, Illinois, USA
Murcia, Spain
Matthew T Olson MD Charles AG Proye MD
Assistant Professor Janice L Pasieka MD FRCSC FACS1 Surgical Professorial Unit
Division of Cytopathology Regional Division Chief in General Department of General and
Department of Pathology Surgery for the Calgary Regional Endocrine Surgery
The Johns Hopkins University Health Authority Lille, France
School of Medicine Head, Division of General Surgery
Baltimore, Maryland, USA The University of Calgary Marco Raffaelli MD
Calgary, Alberta, Canada Professor
Furio Pacini MD Department of Endocrine and
Section of Endocrinology Jesse D Pasternak MD Metabolic Surgery
Department of Endocrinology and Clinical Associate Università Cattolica del Sacro
Metabolism University Health Network Cuore of Rome
University of Pisa Division of General Surgery Rome, Italy
Pisa, Italy University of Toronto
Toronto, Ontario, Canada M Zohair Rahman MD
Department of Biofunctional Chemistry
Miltiadis Paliouras PhD
Francois N Pattou MD Graduate School of Environmental and
Assistant Professor
Professor of General Surgery Life Science
Department of Medicine
Lille University Okayama University
Division of Experimental Medicine
Head, Department of General and Okayama, Japan
McGill University
Endocrine Surgery
Montreal, Quebec, Canada Gregory W Randolph MD FACS FACE
University Hospital
Lille, France Associate Professor
Sareh Parangi Otolaryngology, Head and Neck Surgery
Associate Professor of Surgery Division of Thyroid and Parathyroid
Jennifer M Perkins MD
Department of Surgery Assistant Professor of Medicine Endocrine Surgery
Harvard Medical School Division of Endocrinology Department of Otology and Laryngology
Massachusetts General Hospital Duke University Harvard Medical School
Boston, Massachusetts, USA Durham, North Carolina, USA Boston, Massachusetts, USA
xiv Textbook of Endocrine Surgery

Gustavo G Fernandez Ranvier Jennifer E Rosen MD Carolyn D Seib MD


Assistant Professor Chief, Endocrine Surgery Department of Surgery
Department of Surgery MedStar Washington Hospital Center University of California
Icahn School of Medicine at Washington, District of Columbia, USA San Francisco
Mount Sinai San Francisco, California, USA
New York, New York, USA Daniel T Ruan MD
Assistant Professor Natalie Seiser MD PhD
Bryan K Richmond MD MBA FACS Department of Surgery Endocrine Surgery Fellow
Professor of Surgery Harvard Medical School/Brigham and Department of Surgery
Section Chief Women's Hospital University of California, San Francisco
General Surgery Boston, Massachusetts, USA San Francisco, California, USA
West Virginia University/Charleston
Division Arash Safavi MD Ashok R Shaha MD
Charleston, West Virginia, USA General Surgery Resident
Professor of Surgery
Department of Surgery
Department of Surgery
William S Rilling MD FSIR University of Arizona
Memorial Sloan Kettering Cancer Center
Professor of Radiology and Surgery Tucson, Arizona, USA
New York, New York, USA
Department of Radiology
Division of Vascular and Susan Safley MD
Interventional Radiology Jyotirmay Sharma MD
Department of Surgery
Medical College of Wisconsin Assistant Professor of General and
Emory University
Milwaukee, Wisconsin, USA Endocrine Surgery
Atlanta, Georgia, USA
Division of General and GI Surgery,
Inne HM Borel Rinkes MD PhD Juan J Sancho MD PhD Department of Surgery
Professor Head of Section at Department of Emory University School of Medicine
Department of Oncology General Surgery Atlanta, Georgia, USA
Cancer Center Hospital del Mar-Parc de Salut MAR
University Medical Center Department of General Surgery Wen T Shen MD MA
Utrecht, The Netherlands Barcelona, Spain Associate Professor of Clinical Surgery
Department of Surgery
Philipp Riss MD Abbey Schepers MD PhD Division of General Surgery
Medical University of Vienna Department of Surgery University Of California, San Francisco
Universitätsklinik für Chirurgie Leiden University Medical Center Medical Center at Mount Zion
Vienna, Austria Leiden, The Netherlands San Francisco, California, USA

Jose M Rodriguez MD Randall P Scheri MD Dolores Shoback MD


Professor Assistant Professor of Surgery Professor
Department of Surgery Department of Surgery Department of Medicine
University of Murcia Duke University University of California, San Francisco
Murcia, Spain Durham, North Carolina, USA San Francisco, California, USA

Sanziana Roman MD David F Schneider MD MS FACS


Assistant Professor Stan B Sidhu PhD FRACS
Professor of Surgery
Director, Endocrine Surgery Fellowship Department of Surgery Professor
and Scholars Program University of Wisconsin Endocrine Surgical Unit
Duke Department of Surgery Madison, Wisconsin, USA University of Sydney
Chief of General Surgery Sydney, New South Wales, Australia
Durham VA Medical Center Frédéric Sebag MD
Associate Chief of Surgery for Endocrine Surgery Allan Siperstein MD
Clinical Affairs Assistance Publique des Professor and Chair
Durham VA Medical Center Hopitaux de Marseille Endocrine Surgery Department
Durham, North Carolina, USA Marseille, France Cleveland, Ohio, USA
Contributors xv
Rebecca S Sippel MD Hiroshi Takami MD Jon A van Heerden MD
Associate Professor of Surgery Scientific Adviser Professor of Surgery
Chief of Endocrine Surgery Department of Surgery Medical University of South Carolina
Department of Surgery Ito Hospital Charleston, South Carolina, USA
University of Wisconsin Tokyo, Japan
Madison, Wisconsin, USA Annemieke van Zante MD
Gary B Talpos MD
Associate Professor
General Surgeon
Antonio Sitges-Serra MD Department of Pathology
Henry Ford Hospital
Professor of Surgery University of California, San Francisco
Detroit, Michigan, USA
Department of Surgery San Francisco, California, USA
Universitat Autònoma de Barcelona Phuong Nguyen Thanh MD PhD
Department of General, Aaron I Vinik MD PhD FCP MACP FACE
Barcelona, Spain
Visceral and Vascular Surgery Director of Research and the
University Halle-Wittenberg Neuroendocrine Unit
Julie Ann Sosa MA MD FACS Murray Waitzer Endowed Chair for
Halle (Saale), Germany
Professor Diabetes Research
Departments of Surgery and Medicine Geoffrey B Thompson MD Eastern Virginia Medical School
Duke University Professor of Surgery Norfolk, Virginia, USA
Durham, North Carolina, USA Mayo Clinic College of Medicine
Section of Endocrine Surgery Michel Vix MD
Niranjan Sritharan MD Department of Surgery, Mayo Clinic Doctor
Conjoint Senior Lecturer Rochester, New York, USA Department of Digestive and
School of Medicine Endocrine Surgery
Neil S Tolley BCh MD FRCS (Eng & Ed) DLO
University of Western Sydney University of Strasbourg
Department of Otorhinolaryngology
Penrith, New South Wales, Australia Strasbourg, France
and Head and Neck Surgery
St. Mary's Hospital Menno R Vriens MD PhD
Peter Stålberg MD PhD Imperial College, Healthcare NHS Trust
Professor of Endocrine Surgical
Professor, Department of Surgery London, United Kingdom
Oncology
Uppsala University Department of Surgery
Uppsala, Sweden Emanuela Traini MD
Doctor University Medical Center Utrecht
Department of Endocrine and Utrecht, The Netherlands
Cord Sturgeon MD Metabolic Surgery
Associate Professor of Surgery Università Cattolica del Martin K Walz MD
Department of Surgery Sacro Cuore of Rome Professor of Surgery
Section of Endocrine Surgery Rome, Italy Department of Surgery and Center of
Northwestern University Minimally Invasive Surgery
Chicago, Illinois, USA Frédéric Triponez MD Kliniken Essen-Mitte
Thoracic and Endocrine Surgery Essen, Germany
University Hospitals of Geneva
Insoo Suh MD
Geneva, Switzerland Tracy S Wang MD MPH
Assistant Professor
Associate Professor
Department of Surgery Robert Udelsman MD MBA Department of Surgery
Endocrine Surgery Section Chairman and Professor
Medical College of Wisconsin
University of California, San Francisco Department of Surgery
Milwaukee, Wisconsin, USA
San Francisco, California, USA Yale University School of Medicine
New Haven, Connecticut, USA
Jeffrey D Wayne MD
Denise S Tai MD Associate Professor
Cornelis JH van de Velde MD
Department of Surgery Professor of Surgery Department of Surgery
David Geffen School of Medicine at Department of Surgery Northwestern University
University of California, Los Angeles Leiden University Medical Center Feinberg School of Medicine
Los Angeles, California, USA Leiden, The Netherlands Chicago, Illinois, USA
xvi Textbook of Endocrine Surgery

Colin J Weber MD DMSc William F Young MD Martha A Zeiger MD


William McGarity Professor of Surgery Division of Endocrinology Professor
Department of Surgery Department of Radiology Department of Surgery
General and Endocrine Surgery Mayo Clinic The Johns Hopkins University Hospital
Emory University School of Medicine Rochester, Minnesota, USA Baltimore, Maryland, USA
Atlanta, Georgia, USA
Kyle A Zanocco MD
Justin T Zelones MD
Michael W Yeh MD Chief Resident
Resident
Associate Professor Department of Surgery
Northwestern University Feinberg Department of Surgery
Section of Endocrine Surgery University of California, San Diego
UCLA David Geffen School of Medicine School of Medicine
Chicago, Illinois, USA San Diego, California, USA
Los Angeles, California, USA

JEM Young MD Rasa Zarnegar MD


Clinical Professor of Surgery Associate Professor
Division of Head and Neck Surgery Department of Surgery
McMaster University Weill Cornell Medical College
Hamilton, Ontario, Canada New York, New York, USA
Preface

Endocrine surgery is a field in constant evolution. When surveying the dizzying array of operative approaches,
imaging studies, and biochemical and genetic tests that have become routine components of the endocrine surgeon’s
armamentarium, it is easy for one to forget that this is still a nascent surgical specialty. After all, Theodor Kocher was
awarded a Nobel Prize for developing the technique for safe thyroidectomy in 1909, just a little more than a century ago.
The first successful parathyroid operations took place in the early 1920s. Imaging and surgery for adrenal and pancreatic
tumors were even more recent developments.
In this third edition of Textbook of Endocrine Surgery, we aim to provide a comprehensive, up-to-date survey of
our burgeoning and continually changing field. Since the release of our first edition in 1997, we have witnessed an
explosion of new techniques and technologies, including widespread utilization of intraoperative parathyroid hormone
measurement to facilitate focused parathyroidectomy, the introduction of novel minimally-invasive and robotic
approaches to cervical and retroperitoneal tumors, and the development of molecular testing to more accurately
characterize indeterminate thyroid nodules. All of the existing chapters of our previous editions have been reviewed
and updated, and many new chapters have been added to reflect advancements in the field. We hope this textbook will
continue to serve as an invaluable resource for everyone interested in endocrine surgery, from students to practitioners.
Perhaps the inspiration for the next wave of innovation in endocrine surgery lies within its pages.

Dr Wen T Shen MD MA
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Pettit, John, 29n
Peters, Mrs., 186
Phillips, John, 7
Phillips Rents, 7
Pickering, Joseph, 84
Pierrepoint, Lady Anne, 91
Pierrepont, Lady Mary (afterwards Lady Mary Wortley Montagu), 89
Pillar at Seven Dials, 113–114
Pindar, Peter (Dr. Wolcot), 83
Piozzi, Mrs., 85
Plowden, —, 71
Plumer, John, 21n
Pole, —, 165
Pole, Peter, 180
Pollard, Eliz., 83
Polton, John de, 109
Pont, Mrs., 71
Pope, Thos., 83
Popham, Colonel Alexander, 73
Port of London, scheme for improving, 187
Porter, Endymion, 88
Porter, George, 88
Porter, Lady Diana (Ann), 88
Porter, T. C., 185
Portsmouth, Duchess of (formerly Mdlle. de Keroualle), 54
Portsmouth Street, No. 2, 46
Portuguese Embassy, 65–66, 96, 97
Pound, St. Giles’, 144
Povey, Justinian, 12
Povey, Thomas, 11, 12
Powell, Giles, 106n
Powell, Richard, 36n
Powlet, Lady Ann (afterwards Belasyse), 137
Powlett, Charles, Earl of Wiltshire (afterwards Duke of Bolton), 65
Praed, Wm. Mackworth, 11
Prescott, Jeoffery, 35n, 37n, 40n
Princes Street, 10
Pritchard, —, 56
Pritchard, William, 90
Purcell, Dr. John, 142
Purse Field, 4, 6, 10, 24, 34
Purse Rents, 5, 7
Pynchon, John, 11n
“Pyramide de la Tremblade”, 115

Queen Anne Street West, 58


Queen Anne’s Bath, Endell Street, 105
Queen Anne’s Bounty, 76
Queen Anne’s Wardrobe, 45n, 66
Queenhithe, 117
Queen’s Court, 60
Queen Street. (See Great Queen Street, Little Queen Street.)
Quire, Matthew, 107
Radcliffe, Dr., 56
Radclyff, Thomas, 124
Raftor, William, 71
Ragged Staff Court, 108
Ralph, James, 131
Rawlinson, Mary, 106n, 108n
Raye, Thomas, 60n
Raymond, Ch., 84
Raymond, John, 180
Raynbowe, Richard, 25
Raynseford, Thomas, 6, 7
Read, Jonathan, 3n
Reade, Richard, 14
Reading, Roger, 15n
Redditt, Nicholas, 38n
Reede, Margaret (late Margaret Pennell), 186
Reede, Richard, 186, 187
Reid, Andrew, 179
Reneger, Thomas, 80n
Reynolds, Joshua, 76–77
Rich, Sir Henry, 126
Rich, Henry, 1st Earl of Holland, Baron Kensington, 88
Rich, Robert, Baron Kensington, 5th Earl of Warwick, 88
Richard II., 23
Richard, Lewis, 10n
Richardes, Lewis, 40n
Richardson, C. J., 63
Richardson, Jas., 163
Richardson, Jonathan, 76
Richardson, W. Westbrook, 83
Richold, —, 83
Ride, Miss, 71
Ridge, Jeremiah, 106n
Risley, Thos., 126
Rivers, Arabella, Lady, 69
Rivers, Elizabeth Scroope (afterwards Countess), 68
Rivers, Elizabeth, Countess of (née Darcy), 59, 67–68, 73n, 90
Rivers, John Savage, 2nd Earl, 68
Rivers, Margaret, Lady (formerly Tryon), 69
Rivers, Mary, Countess Dowager, 68n
Rivers, Penelope, Lady, 69
Rivers, Richard, 4th Earl (“Tyburn Dick”), 69, 70
Rivers, Thomas Darcy, Baron Darcy of Chich (afterwards Earl), 67
Rivers, Thomas Savage, 3rd Earl, 68, 69
Rivers House, Great Queen Street, 59, 63, 67
Roberts, Thomas, 13, 14
Robins, Richard, 107
Robinson, Mr., 77–78
Robinson (née Darby), Mary (“Perdita”), 77–78
Rochford, Bessy, Countess of, 70
Rochford, Frederick Nassau de Zuylestein, 3rd Earl of, 70
Rochford, William Henry, Earl of, 70n
Roger, son of Alan, 107
Ronquillio, Don Pedro de, 97n
Rookery, St. Giles, 145–146
Roos (Rous), Lord, 80n, 91, 92
Rope, Master, 126n
Roper, Poyser, 39
Ros of Hamlake, Barony of, 91n
Ros of Roos, Barony of, 91n
Rose Inn, 27, 28, 123
Rose, tenement in Lewknor’s Lane, 28
Rose Field, 18, 20, 27–32, 34
Rosslyn, Alexander Wedderburn, Earl of, 155
Round Rents (Middle Row), Holborn, 125
Rous. (See Roos.)
Rowland, Percival, 122n
Rowlandson, William, 139
Rowley, —, 90
Royal, Mrs., 163
Rudd, Ric., 92
Rudd, Thos., 92
Russell, Francis, Earl of Bedford, 23n, 51n
Russell, Lady Rachel, 126
Russell, Thos., 115n
Russell, William, Lord, 75
Rutland, Duchess of, 70n
Rutland, Earls of, 91
Rutland, John Manners, 9th Earl of. (See Roos.)
Rymes, William, 3n
“Sacharissa” (Dorothy Spencer, Countess of Sunderland), 54
Sadler, Ric., 89
Sadler (alias Clarke), Thomas, 80
St. Albans, Earl of (Marquess of Clanricarde), 46, 47, 50, 59
St. Amond, Jas., 65n
St. Andrew Street, 113
St. Giles, Cripplegate, Charity Schools, 112
St. Giles-in-the-Fields Church, 127–140
St. Giles-in-the-Fields, Hospital of, 20, 23, 34, 107, 109, 111, 117–126,
186
St. Giles-in-the-Fields, Rectors of, 87, 139
St. Giles’s Lane, 23n, 35n
St. Giles’s Pound, 144
St. Giles, Vestry of, 26
St. Giles’ Wood, Edmonton, 125
St. Giles’ Workhouse, 109, 110
St. John, Lord, Earl of Wilts., and Marquess of Winchester, 95, 96,
137
St. John of Jerusalem, Priory of, 3, 7
St. John’s Court, 76
St. Lazarus of Jerusalem, Order of, 118
St. Mary Graces, Abbot of, 117–118
St. Thomas’s Street (now Shelton Street), 27, 31
Salisbury, Gilbert Burnet, Bishop of, 75
Salisbury, Robert Cecil, Earl of, 36
Salisbury, Thomas, 139
Salvadore, —, 66
Sandby, Thomas, 61, 62, 63
Sanders (Saunders), Mary, 96
Sandfeild, William, 38
Sandwich, Edward Montagu, 1st Earl of, 89
Sardinia Ambassador, 45n
Sardinia Place, 34
Sardinia Street, 93, 94, 100
Saunders, —, 89
Savage, —, 84
Savage, Miss Bessy (afterwards Countess of Rochford), 70
Savage, Elizabeth (afterwards Lady Thimbleby), 90
Savage, Elizabeth (née Darcy), Countess Rivers, 59, 67, 68, 73n, 90
Savage, J., 89
Savage, John, 2nd Earl Rivers, 68
Savage, Lady Mary, 68
Savage, Sir Thomas (afterwards Viscount Savage), 67, 90
Savage, Thomas, 3rd Earl Rivers, 68, 69
Savill, Miss, 71
Sayes Court, Addlestone, 114
Saywell (née Lloyd), Elizabeth, 119–120
Schmidt, Bernard (Father Smith), 132
Scott, —, 172
Scott, John, 1st Earl of Eldon, 155
Scott, Sir John, 186
Scott, John (Rector), 139
Scott, William, 150
Scott, William (afterwards Lord Stowell), 155
Scroope, Adrian, 102
Scroope, Elizabeth (afterwards Countess Rivers), 68
Scroope, Sir Gervase, 102
Seagood, Henry, 35, 37, 40, 41
Seal, Office of the Lord Keeper of, 79, 80, 81
Seales, Major, 91
Segar (Seager), Sir William and Lady, 6n
Seven Dials, 113–114
Seven Dials. (See also Marshland.)
Seven Dials Mission, 116
Seymour, Francis, 5th Baron Conway, 61n
Seymour (alias Conway), Popham, 78, 82
Shaftesbury Avenue, 112n, 113, 118
Sharp, John, 139
Shaw, Charles (afterwards Shaw-Lefevre), 160
Shaw-Lefevre, Charles (afterwards Viscount Eversley), 160
Shaw-Lefevre, Sir John George, 160
Sheffield, Edmund, 2nd Earl of Mulgrave, 73
Sheffield, John, Marquess of Normanby, 73–74
Sheffield Street, boundary stone in, 1
Sheldon, Lady Henrietta Maria, 90
Sheldon, John, 147, 149
Sheldon, Ralph, 90
Shelton Street, 27, 30–31
Shenton, Mrs., 17
Shenton’s Tenements, 16, 17
Sherbourne, Richd., 11
Sheridan, Richard Brinsley, 66–67
Sheridan, Thomas, 66
Shiffner, Henry, 84
Ship Tavern, Gate Street, 12
Short, Dudley, 109
Short, Gregory, 18n
Short, Thomas, 106, 108, 109
Short, William (the Elder), 28, 101, 106
Short, William (the Younger), 18, 19, 27n, 28, 29, 30, 31n, 101, 110,
112
Short’s Gardens, 101, 106–111
Sidney, Algernon, 81
Sidney, Henry, 54
Skinner, Sir John, 175
Slingsby, —, 79
Slingsby, Henry, 53n, 79
Smallbone, Sir John, 110n
Smart, John, 22
Smart, Lewis, 22
Smart, William, 22
Smart’s Buildings, 18–22
Smith, Edward, 80n
Smith (Smyth), Edward, 106, 110, 121
Smith, Father (Bernard Schmidt), 132
Smith, John, 125
Smith, John, of Tudworth, 76
Smith, Lilley, 89
Smith, Thomas, 67, 72n
Smith, Thomas, 11
Smithfield Gallows, 144
Smithson, George, 6n, 8n
Smyth, John, 139
Smyth, Katherine (alias Katherine Clerke), 24
Soane, Sir John, 63
Soho Square, 76
Somaster, Sir Samuel, 19n
Southampton, Henry, 3rd Earl of, 126
Southampton Buildings, 77
Southampton Square, 56
South Crescent, 186
Southgate, Rev. Richard, 136
Spanish Ambassador, 47, 59, 67, 96, 97
Sparkes, John, 41
Speaks, Hugh, 6n
Speckard, Abraham, 122
Speckard, Dorothy, 122
Spencer, Lady, 95
Spencer, Anne (née Digby), Countess of Sunderland, 54
Spencer, Lady Diana (afterwards Beauclerk), 149
Spencer, Dorothy (Countess of Sunderland) (“Sacharissa”), 54
Spencer, Henry, 1st Earl of Sunderland, 54
Spencer, Robert, 2nd Earl of Sunderland, 54
Spiller, Sir Henry, 29n
Spittle Houses, St. Giles’s Hospital, 118, 121–122, 125
Stafey, John, 119n, 121n
Stainsforth, George, 151
Stamford, Thomas Grey, 2nd Earl of, 65
Star, High Holborn, 3n
Statue of Queen Henrietta Maria, 44, 59, 60, 61, 71–77
Steers, Charles, 149
Stephenson, Jno., 165
Stephenson, Mrs., 165
Steward, P. G., 61
Steward, William, 139
Stewart, G., 92
Stidwell Street, 123, 141
Stoake, Thomas, 40n
Stockwood, Edward, 3
Stonor, Thos., 47, 48, 54n, 55
Stowell, William, Lord, 155
Stradling, Sir Edward, 42, 43, 93, 94, 100n
Stradling, Sir Edward (Junior), 94n
Stradling House, 95
Strange, Sir Robert, 44n
Stratton, Edward, 94n
Stratton, Elizabeth, 17n
Stratton, Henry, 110
Stratton, Robert, 35n
Strode, George, 42, 93
Stuart, Esmé, Seigneur D’Aubigny, Earl of March (afterwards Duke
of Lennox), 72, 101
Stuart, George Seigneur D’Aubigny, 60, 72
Stydolph, Sir Francis, 112, 113
Stydolph, Sir Richard, 113, 122, 123
Stydolph, Thomas, 112
Suffolk, Earl of, 72
Sun and Dolphin, High Holborn, 3n
Sunderland, Anne, Countess of, 54
Sunderland, Dorothy Spencer, Countess of (“Sacharissa”), 54
Sunderland, Henry Spencer, 1st Earl of, 54
Sunderland, Robert Spencer, 2nd Earl of, 54
Sussex, Duke of, 62
Sutton, George, 27–28
Swan, The, 107, 108
Swan on le Hop, 108
Symonds, R., 11

Tahairdin, Peter, 67n


Talbot, Hon. Catherine, 136
Talbot, Hon. John, 136
Tamworth, Viscount, 75n
Tatnell, Wm., 171
Tattershall, Widow, 96
Tavistock, Francis, Marquess of, 149
Tavistock, Lady, 149
Taylor, Ed., 56
Taylor, Dr. John, 89
Taylor, Richard, 28n
Taylor, W. A., 113–114
Taylor, William, 15n
Temple, Freemasons’ Tavern, 61, 62
Thanet, Thomas Tufton, 6th Earl of, 147, 148
Thanet House, 147–149
Theedham, Edward, 108
Thelwall, Daniel, 6, 8n
Theobalds, Hertfordshire, road to, 36, 42
Thimbleby, Elizabeth, Lady, 89–90
Thimbleby, John, 90
Thimbleby, Sir John, 11n, 90
Thomas, —, 92
Thomas, Mrs., 92
Thomson, Mrs. Anne, 11
Thomson, William, 11
Thornton, Beatrice, 9
Thornton, John, 9
Thornton’s Alley, 9
Thorold, Anthony W., 138
Three Anchors, Salisbury Court, 82n
Three Feathers Tavern, High Holborn, 8
Thriscrosse, Francis, 38
Tomkins, Packington, 73n
Tompson, Elizabeth (afterwards Hollinghurst), 8
Tooke, Edward, 27n, 28, 30n
Tottenham Court Road, 187, 188
Tower Street, 113n
Trinity College, 16
Troughton, —, 119
Trueman (alias Johnson), William, 80n
Tryon, Charles, 122
Tryon, Mrs. Margaret, 69
Tubb, Marchant, 163
Tubbs, Robt., 165
Tufton, Lady Margaret, 148
Tufton, Thomas, 6th Earl of Thanet, 147, 148
Turngatlane, 3
Turnpiklane, 3
Turpin, Jeremiah, 19
Twelves, John, 71
Twiney, J., 83
Twisden, Sir Thomas, 11
Twisden, Sir William, 11
Twyford Buildings, Gate Street, 12
“Tyburn Dick”, 69
Tyburn Gallows, 144
Tye, Dr., 162
Tyler, Rev. James Endell, 105
Tyler, William, 61, 62

Umfreville, Chas., 103n


Umfreville, Gilbert, 103n
Unicorn Inn, High Holborn, 8, 9
Unicorn Yard, High Holborn, 8
Vanblew, —, 76, 77n
Van Helmont, —, 78
Varney, Frances, 120
Vaughan, Elinor, 18
Vaughan, Thomas, 18
Vaughan, Thomas (“Dapper”), 71
Vaune, Mr., 90
Vavasour, Anne, 20
Vavasour, John, 20, 101, 107, 108, 110, 144
Vavasour, Nicholas, 144
Vere, Lady, 31
Vere, Sir Horace, 51
Verney, Edmund, 121
Verney, Sir R., 120n
Vernon, Mr., 77
Verrinder, Dr. G. C., 132
Vertue, —, 44
Vestry of St. Giles, 26
Villiers, George, 1st Duke of Buckingham, 91n
Villiers, George, 2nd Duke of Buckingham, 91n
Villiers House, 53n
Vine, The, High Holborn, 123, 124
Vine Street (now Grape Street), 124
Violetti, Eva Maria, 90n
Vuidele, Anthony, 119

Waldron, John, 6
Wales, George, Prince of (afterwards George IV.), 78
Walgrave, John, 28, 107
Walker, Dr. Jas., 11
Walker, John, 13, 14
Walker, Richard, 163
Walker, Thomas, 29n, 31n
Walpole, Horace, 44, 46, 56n, 71
Walter, Peter, 105
Walton, Brian, 139
Ward, James, 92
Wardrobe, Great Queen Street, 45n, 66
Warner, Henry, 34n
Warwick, Charles, Earl of, 88
Warwick, Robert, Earl of, 88
Watson, Mrs., 96
Watson, Henry, 149
Watson, Mary, 96
Watson, Rowland, 5, 6
Watson, William, 5
Watson, Sir William, 133
Wayte, Edward, 79
Webb, Barbara (afterwards Viscountess Montagu), 65
Webb, Lady Barbara, 65, 136
Webb, Sir John, 47n, 65n, 136
Webb, John, Architect, 44
Webb, Philip Carteret, 73n, 74
Webb, Rhoda (afterwards Beavor), 75
Webb, Richard, 38
Webb, Thos., 71
Wedderburn, Alexander, Lord Loughborough (afterwards Earl of
Rosslyn), 155
Weedon, Thomas, 96
Weld, Lady Frances, 94, 95n
Weld (Wild, Wield), Humfrey, 59, 60, 94, 95n, 96, 97n, 100
Weld House, 93–97, 99
Weld Street. (See Wild Street.)
Wesley, John, 115, 116
Wesleyan Chapel, Great Queen Street, 86–92
West London Mission, 88, 115
West Street, 112n, 115
West Street Chapel, Seven Dials, 87
Western, Thomas, 11
Weston (Whetstone), John, 5n
Westone, William, 109n
Wetherell, Philip, 21n
Wharton, Philip, 4th Lord, 79, 120
Whetstone, William, 6–7
Whetstone Park, 4, 8
White, James, 28, 112
White Hart, 14, 19, 20, 23, 24, 25, 28, 29n, 30n, 123
White Hart Feilde, 6
—(See also Pursefield.)
White Hart Yard, 26
White Horse in Drury Lane, 35
White House, St. Giles’s Precinct, 121
White Lion Street, 113n, 114
Whitesaunder, Thomas, 119
White Swan in Queen Street, 37n
Whitfield, Henry Fotherley, 31n
Whitfield, Thomas, 110n, 111n
Wigg, William, 110n, 111n
Wild. (See Weld.)
Wild Boare Alley, 18
Wild Court, Nos. 6 and 7, 98
Wild Street (Weld Street), 34, 93–97
—(See also Little Wild Street.)
Wilkes, John, 74–75
Wilkinson, William, 125
Wilkinson’s Close, 125n, 187
Williams, Jas., 165
Williams, John, 84
Williams, Paul, 40n
Williamson, Sir Joseph, 69
Williamsfeild (alias Church Close), 145
Willoughby, Philip, 60n
Willson, Thomas, 138
Wilson, Benjamin, 56, 57, 66, 67n
Wilson, Jas., 56
Wilson, Major, 57
Wilton House, Picture of Lincoln’s Inn Fields, 46
Wiltshire, Charles Powlett, Earl of (afterwards Duke of Bolton), 65
Winchester, John, Marquiss of, 95, 96, 137
Windell, Richard, 109n
Windham, W., 67
Winstanley, J., 11
Wise (Wyse), Joan (afterwards Briscowe), 107, 119
Wise, John, 107n
Wise, Robert, 20
Wither, Thomas, 60n
Withers (Wither, Wyther), Anthony, 51, 60, 73n
Withers, William, 74
Wolcot, Dr. (Peter Pindar), 83
Wolstenholme, John, 96
Wood, Anthony, 80
Woodville, Thomas, 130
Woodward, William, 14
Worcester, Edward (1st Marquess of), 73
Worliche, Mary, 9n
Worlidge, Mrs., 77
Worlidge, Thomas 58, 67n, 76, 77
Worsley, John, 96
Wortley, Sir Francis, 89
Wray, Sir John, 95n
Wren, Sir Christopher, 123, 147
Wren, Stephen, 147
Wright, —, 96n
Wright, Martin, 89
Wriothesley, Lord, 124
Wylson, —, 119
Wynter, Master, 119
Wyse. (See Wise.)

Yarmouth, 1st Earl of, 52


York, Frederica, Duchess of, 114
York, Sir William Dawes, Archbishop of, 110n
Young, Thomas, 110

Zucchi, Antonio, 151, 153, 163, 176


Zuylestein, Frederick Nassau de, 3rd Earl of Rochford, 70

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