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Science Activity Sheet
Quarter 4- MELC 2
Week 3-4
A Biomolecules
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REGION VI – WESTERN VISAYAS
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Science 10
Activity Sheet No. 2: Biomolecules
First Edition, 2021
Republic Act 8293, section 176 states that: No copyright shall subsist in any
work of the Government of the Philippines. However, prior approval of the
government agency of office wherein the work is created shall be necessary
for exploitation of such work for profit. Such agency or office may, among
other things, impose as a condition the payment of royalties.
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Introductory Message
Welcome to Science 10!
This Science 10 Activity Sheet will help you facilitate the teaching-learning activities for
the specified Most Essential Learning Competency (MELC) with minimal or no face-to-face
encounter between the teacher and the learner. This is made available to the learners with
the references/links to ease independent learning.
This Science 10 Activity Sheet was developed to help you continue learning even if
you are not in school. This learning material provides you with meaningful and engaging
activities for independent learning. Being an active learner, carefully read and understand
the instructions then perform the activities and answer the assessments. This will be returned
to your school and teacher on the agreed schedule.
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Name
___ of Learner: ____________________________________________________
Grade - Section: __________________________Date: _____________________
A. CARBOHYDRATES
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Types of Carbohydrates
Figure 1 below is a concept map the classification of carbohydrates
Carbohydrates
Simple Complex
• Basic of carbohydrates. Examples are from soft drinks, candy, cookies and other
sweet snacks which are often made with white sugar, a form of processed sugar.
• Natural sugars like found in fruit, milk and vegetables and honey are also simple
carbohydrates.
Complex carbohydrates
• Important energy source for the body.
• Provide the sustained fuel the body needs for exercise, daily living activities and
even rest. They are often containing single units (monosaccharides), which are
bound together.
• The different types of carbohydrates that can be classified on the basis of their
behavior on hydrolysis are mainly classified into three groups: monosaccharides,
disaccharides and polysaccharides.
Monosaccharides:
• Tastes sweet and soluble (they dissolve) in water.
• It possesses a free aldehyde (CHO) or ketone (C=O) group and two or more
hydroxyl (OH) groups.
• The only sugar that can be absorbed and utilized by the body and cannot be
hydrolyzed further to give simpler units of polyhydroxy aldehyde or ketone.
• Aldose is called to a monosaccharide that contains an aldehyde group and ketose
is called to a monosaccharide that contains keto group.
• Types are glucose, galactose and fructose bearing the same formula C6H12O6.
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Table 1. The Monosaccharides
Name Derivation of Name and Source
Glucose • From Greek word for sweet wine, grape; sugar; blood s
sugar;dextrose, aldehexose.
• Most abundant monosaccharide in nature.
• Found in bloodstream and provides the immediate source of energy
of the body’s cells and tissues.
• Essential energy source for all body function
Galactose • Is a Greek word for milk: “ galact”; fthat can be found in milk as
lactose component
• Does not occur or seldom occurs freely in nature
• It is produced in the body during the digestion of a disaccharide
• It binds with glucose to form sugar lactose in milk
Fructose • The Latin word for fruit: “ fructus”; which is also known as levulose,
found in fruits and honey; sweetest sugar
• 1.5 times sweeter than sucrose
• Can be found also in the nectar of flowers, molasses, and honey
• It is sometimes used as a low-calorie sweetener because less
fructose is needed to produce the same sweetness that table
sugar does.
Figure 2 below shows the chemical structure of glucose, galactose and fructose. Notice that
they have the same chemical formula whih is C 6H12O6 but they differ in the structure.
Compounds with the same molecular formula but differ in structure are called isomers.
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Dissacharides
• Two monosaccharides are joined together by covalent bond as glycosidic
linkage in the process of dehydration synthesis to form a disaccharide
molecule.
• These are also soluble in water and taste sweet.
• All disaccharides has a molecular formula of C12H22O11.
Table 2.The Disaccharides
Name Derivation of Name and Source
Sucrose A French word for sugar; “ sucre”; it is a disaccharide which
contains glucose and fructose; table sugar, cane sugar,
beet sugar.
Lactose Latin word for milk: “ lact”; a disaccharide found in milk
containing glucose and galactose
(milk sugar)
Maltose From “ malt” french word; a disaccharide containing two
units of glucose; found in germinating grains; used to make
(malt sugar)
bear.
Condensation reaction
• a reaction when two molecules or parts of the same molecule combine.
• during this process, two monosaccharides combine to form disaccharides, one
molecule of water is lost. Maltose is form and water is lost during the process
when two glucose molecules are combined and water is lost during the process.
Hydrolysis reaction
• occurs when the bond between monosaccharides is broken with the addition of a
water molecule.
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Polysaccharides
• Carbohydrates that contain ten monosaccharide units or more
• Starch, glycogen and cellulose are the common polysaccharides.
In Figure 3 above
• Water molecule breaks the starch to produce H+ and OH- to the site where the
bond is broken.
• The enzymes help separates the glucose units in the digestive system and can be
absorbed and used as fuel by the cells.
• The glucose is released to the cells gradually since it takes time for glucose to be
separated from the polysaccharide.
• Athletes often eat meals rich in complex carbohydrates before an athletic event in
this reason because the glucose from starch reaches muscle cells over a period
of time providing energy as it is needed.
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.
Figure 4 Structure of Glycogen
http://www.natuurlijkerwijs.com/english/Glycogen_metabolism.htm .
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• As for the economic importance, papers and fibers are the products of cellulose
and is chemically modified to yield substances used in the manufacture of items
such as plastics, photographic films, and rayon.
• Some other cellulose derivatives are used as adhesives, explosives, thickening
agents for foods, and in moisture-proof coatings. Industrial applications of starch
are the following: used in the manufacture of paper, textiles, pharmaceuticals, and
biodegradable polymers, and as an additive in foods.
A. LIPIDS
Role of lipids:
1. Fuel reserve of the body. It stores excess energy for future use by using it to
bond atoms together in lipid molecules.
2. Lipids are components of membrane structure and regulate the membrane
permeability.
3. They serve as source of fat-soluble vitamins
4. Lipids are important cellular metabolic regulators
5. Lipids protect the internal organs and serve as insulating materials
Fats and oils are the most abundant of the lipids and they are also called
triglycerides. Unsaturated fatty acids are present in oils that are liquids at room
temperature and contain unsaturated fatty acids. Most oils, such as vegetable oil,
corn oil, and olive oil are produced by plants.
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Most of the fats and oils in your diet consist of fatty acids that are bonded to a
glycerol molecule.
Saturated fats are fats that are solid at room temperature. Examples are butter, lard
and animal fats.
Atherosclerosis is a heart ailment when there is too much saturated fats in the diet.
When a lipid is saturated, the acid chains are straight because all the bonds are single
bonds as shown in Figure 7.
Unsaturated fat are fats that are liquid at room temperature. Examples are Corn oil,
olive oil, canola oil and other vegetable oil. They are not harmful to your health.
When a lipid is unsaturated, the molecule bends wherever there is a double bond as
in figure 7. The label “hydrogenated vegetable oil” on margarine means
unsaturated fats have been converted to saturated fats by adding hydrogen atoms.
Waxes composed of long chains of fatty alcohols, or an ester of alcohols and fatty
acids. They do not mix with water. This property makes them effective natural coatings
for fruits. Many insects also have waxy coats to prevent their bodies from drying out.
Example are bees wax, lanolin or wool fat, sebum, cerumen, plant wax and paraffin
wax
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Phospholipids are structurally similar to fats, but contain the element
phosphorus and only two molecules of fatty acids. They are the major components
of cell membrane, forming a double layer that shields the cell from its environment.
Figure 8 shows the unique structure of cholesterol which consists of four linked
hydrocarbon rings forming the bulky steroid structure. A tail linked to one end of the
steroid is attached by a hydrocarbon and to the other end linked is a hydroxyl group.
Cholesterol
• Known as a “sterol” because it contains an alcohol functional group-OH.
• Absent in prokaryotes and present in most animal membranes with varying
amounts
• Plays an important role in eukaryotes and especially abundant in cell membranes
of animal cells and small amount of cholesterol can also be found in the membrane
of some organelles inside the cells
• Found to be the most important factor in the formation of synapses which greatly
affect our memory and learning ability.
• Steroids like cortisone, testosterone, and estrogen are synthesize by animals
by using cholesterol.
• Disorders caused by the buildup of lipids are called lipidoses; Tay Sachs disease
is an example.
• Fatty acid oxidation disorders is one of the abnormalities in enzymes that
prevent lipids from being converted into energy.
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B. PROTEINS
• The most important groups of biomolecules in living cells they help build and
repair body parts.
• Came from the Greek word proteis meaning “first place” which suggests the
importance of these molecules in living systems.
• Made up of the elements carbon (C), hydrogen (H), oxygen (O), nitrogen (N) and
sulfur (S).
• Example of the foods rich in protein are egg white, fish meat, animal meat, milk,
tuna, cheese, tofu and beans.
Amino Acids
• Amino acids are the building blocks of protein. An amino acid is composed of a
central carbon (C) bonded to a hydrogen (H), a carboxyl group (- COOH), an
amino group (- NH2), and a side chain or R group.
• There are twenty different amino acids and can be classified as essential and non-
essential amino acids.
• Essential amino acids cannot be synthesized by the body but it is of great
importance in our diet and can be obtained from the food. There are nine essential
amino acids and adults’ only need to obtain eight of them: valine, isoleucine,
leucine, lysine, methionine, phenylalanine, threonine and tryptophan. The
ninth amino acid - histidine - is only essential for infants.
• There are 11 non-essential amino acids, of the 11 nonessential amino acids, eight
are called conditional amino acids that includes arginine, glutamine, tyrosine,
cysteine, glycine, proline, serine, and ornithine. The remaining three - alanine,
asparagine, and aspartate - are nonessential. When you’re sick or under
significant stress, your body may not be able to produce enough of these amino
acids to meet your needs.
Amino Acid Structure
H H O
+H N C C
H R O
R-group
(variant
Figure 9. Structure of Amino Acids
http://entrytest-preparation.blogspot.com/2014/01/amino-acids.html
Figure 9, shows the structure of amino acids. Amino acids are organic molecules
that contain two functional groups: a basic NH2 amino group and an acidic- COOH
carboxylic acid group.
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Amino acid 1 Amino Acid 2
R1 O R2 O
HC C + HC C
NH2 OH NH OH
H H2O
O
R2 R2 O
C Dipeptide
HC C HC
NH2 NH OH
Peptide bond
Figure 3. Peptide Bond
Taken from the Grade 10 Science Learner’s Module
Peptide bond is formed when two amino acids react with each other in an acid-base
reaction. The basic amino group of one amino acid reacts with the acidic carboxylic
group of another amino acid, forming the peptide, and a molecule of water is lost.
The reaction shown above is classified as a condensation reaction because the two
amino acid molecules join together and water is formed. The bond formed is called
a peptide bond, and the product is a dipeptide because it is made up of two amino
acid units. Longer chains are called polypeptides and chains of 50 or more amino
acids are called proteins.
Structure of Proteins
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Primary structure is the linear sequence of amino acids that form a protein
pleated sheet which make up the chain.
Secondary structure is the spatial arrangement of the polypeptide chain of a
protein. The secondary structures of proteins refer to the coiling of the protein chain
into a α–helix structure, formation of b sheets, or twisting into random structures.
Tertiary structure describes the shape of the coiled chain when it is folded or
hydrated in its natural state. It refers to the final three-dimensional shape of a single
polypeptide molecules where the alpha helix and the pleated sheet are folded forming
a globular protein. It termed globular since proteins are approximately spherical in
shape.
Quaternary protein structure involves the clustering of several individual
peptides into a final specific shape. Quaternary structure refers to the overall shape
when two or more polypeptides bind each other. A good example of this structure is
hemoglobin, the oxygen carrier in the blood.
Kwashiorkor is a disease for lack of nutrition in the body especially for young
children. It also known as protein malnutrition or calorie malnutrition and referred to as
Protein- Energy Malnutrition (PEM).
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C. NUCLEIC ACIDS
Nucleic acids are molecules that code for hereditary traits by controlling the
production of protein. Like proteins, nucleic acids are long chain of polymers consisting
of simpler units or monomers. There are two kinds of nucleic acids: DNA, or
deoxyribonucleic acid; and RNA, or ribonucleic acid. DNA found mainly in the cell
nuclei contains the genetic information that codes for the sequences of amino acids in
proteins. RNA is found in many places in the cell and carries out the synthesis of
proteins. The monomers of nucleic acids are nucleotides. They are made up of three
parts: a five-carbon sugar (pentose), a phosphate group, and a ring-shaped base
containing nitrogen. Refer to figure 11 below.
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The building of living organisms are the nucleic acids. Just like proteins,
nucleic acids are the most important biomolecules. They serve as the blueprint of life.
They are responsible in encoding, transmitting and expressing genetic information.
Figure 12 below are the structure of DNA and RNA.
Table 5. Summary of the differences between the two kinds of nucleic acids:
DNA RNA
Deoxyribonucleic Acid Ribonucleic Acid
Description It contains the genetic It is responsible for
instruction used in the template in the
the development and synthesis of proteins
functioning of all living which in turn control the
modern organisms. operation & function of
the cell
Function Long-term storage and Transfer the genetic
transmission of genetic information for the
information creation of proteins
from the nucleus to the
ribosomes
Sugar and Bases Deoxyribose sugar Ribose sugar
Phosphate backbone; Phosphate backbone;
Four Bases: adenine, Four Bases: adenine,
guanine, cytosine, and guanine, cytosine, and
thymine uracil
Pairing of Bases A-T (Adenine-Thymine) A-U (Adenine-Uracil)
G-C (Guanine-Cytosine) G-C (Guanine-Cytosine)
Unique Features The helix geometry of The helix geometry of
DNA is of B-form, which RNA is of A-form RNA
means it is a double helix. strands are continually
DNA is completely made, broken down, and
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protected by the body, reused RNA is more
and that is, the body resistant to damage by
destroys enzymes that ultraviolet rays.
leave DNA. DNA can be
damaged by exposure to
ultra violet rays
Predominant structure Double-stranded molecule A single-stranded
with a long chain of molecule in most of its
nucleotides biological roles and has a
shorter chain of
nucleotides.
Stability Deoxyribose sugar in Ribose sugar is more
DNA is less reactive reactive because of C-OH
because of C-H bonds; (hydroxyl) bonds, not
stable in alkaline stable in alkaline
conditions. DNA has conditions; RNA has
smaller grooves, which larger grooves, which
make it harder for makes it easier to be
enzymes to “attack” DNA attacked by enzymes
Propagation DNA is self-replicating RNA is the synthesized
from DNA when needed
Location nucleus cytoplasm
http://www.diffen.com/difference/DNA_vs_RNA)
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IV. Activity Proper:
Activity 1:
Let’s Try this!
Direction: Consider the different kinds of food below. Classify as carbohydrates,
lipids, nucleic acids or proteins. Write the answer on your answer
sheet.
Food Biomolecules
1.
www.medicalnewstoday,com
2.
3.
http://www.imgt.org/IMGTeducation/Aide-
memoire/_UK/aminoacids/formuleAA/
4.
https://www.first-learn.com/fats-for-
energy-and-warmth.html
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For nos. 6-10. Classify the structure of biomolecules below as carbohydrates,
lipids, nucleic acids or proteins. Write the answer on your answer sheet.
Structure Biomolecules
6.
7.
8.
9.
10.
For Nos. 11-15. Refer to items 1-6 in the table above. Recognize the importance of
each structure of biomolecules (carbohydrates and lipids) by answering each
question below. Write the number of the correct biomolecule on the space provided.
________11. Which of the given structures represents molecules that provide the
immediate source of energy of the body’s cells and tissues?
________12. Which of the given structures represents molecules that
serves as the main storage form of glucose in the body?
________13. Which of the given structures represents molecules that store excess
energy for future use?
________14. Which of the given structures represents molecules that build and
repair body parts?
________15. Which of the given structures represents molecules that serves as the
blue print of life?
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V. Reflection
Questions:
1. Samantha Therese is an oversized woman. She always loves to eat
especially foods that are rich in carbohydrates and fats. What do you think will
happen to a person if excessive carbohydrates and fats will be taken on the
diet?
___________________________________________________________________
___________________________________________________________________
2. Some people in remote areas have lack or low levels of education and don’t
understand how to eat a proper diet. This is the reason why most of the children
have enlarged and swollen stomach which is due to edema (an excess water
retention in body tissues). What do you think is a disease that affects those
children? What causes this disease?
_____________________________________________________________________
_____________________________________________________________________
3. Why do siblings resemble with each other? Why mother and daughter look
alike?
_____________________________________________________________________
_____________________________________________________________________
4. Why do siblings resemble with each other? Why mother and daughter look
alike?
_____________________________________________________________________
_____________________________________________________________________
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VI. Answer Key
Activity 1. Let’s Try This
1-3. Answer varies
Reflection:
Baguio, SS.M., Felicerta C.N., Mañosa S.D & Sanitsteban-Cook C.J.C. (2015). Breaking
Through Science 10
Valdoz,M.P., Aquino, M.D., Biong, J.A. & Andaya M.O. ( 2015). Science Links (Worktext for
Scientific and Technological Literacy)
https://byjus.com/chemistry/classification-of-carbohydrates-and-its-structure/
http://www.sci.uidaho.edu/bionet/biol115/t2_basics_of_life/lesson2.htm#Carbohydrate
https://courses.lumenlearning.com/wm-biology1/chapter/reading-types-of-carbohydrates/
https://courses.lumenlearning.com/wm-biology1/chapter/reading-types-of-carbohydrates/
https://www.verywellhealth.com/difference-between-saturated-fats-and-unsaturated-fats-
697517
https://www.google.com/search?q=structure+of+cholesterol&oq=structure+of+cholesterol&aqs
=chrome..69i57.11297j0j7&sourceid=chrome&ie=UTF-8
https://davidson.weizmann.ac.il/en/online/askexpert/chemistry/what-difference-between-
saturated-and-unsaturated-fat-and-what-are-trans-fats-eyal
https://www.creative-proteomics.com/blog/index.php/fatty-acids-types-roles-and-analysis/
https://www.first-learn.com/fats-for-energy-and-warmth.html
https://www.medicalnewstoday,com
http://pnhs.psd202.org/documents/rkieft/1500929211.pdf
https://www.lee.k12.nc.us/cms/lib03/NC01001912/Centricity/Domain/701/Lipid%20Worksheet.
pdf
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http://www.biologyforlife.com/uploads/2/2/3/9/22392738/06_lipids_ws.pd
https://www.mrgscience.com/uploads/2/0/7/9/20796234/lipids_worksheet_answer_key.pdf
http://mrsslovacek.weebly.com/uploads/5/8/2/5/58255793/lipids_worksheet_key_2016.pdf
http://www.natuurlijkerwijs.com/english/Glycogen_metabolism.htm.
https://www.researchgate.net/figure/Structure-of-cellulose_fig3_235407157
https://www.quora.com/What-is-the-difference-between-saturated-and-unsaturated-fat-in-
foods
https://www.toppr.com/ask/question/the-diagram-shows-the-structure-of-cholesterolwhich-
statements-about-cholesterol-are-correct1-the-molecule-contains/
http://www.imgt.org/IMGTeducation/Aide-memoire/_UK/aminoacids/formuleAA/
http://entrytest-preparation.blogspot.com/2014/01/amino-acids.html
https://byjus.com/chemistry/protein-structure-and-levels-of-protein/
http://www.diffen.com/difference/DNA_vs_RNA)
http://www.sci.uidaho.edu/bionet/biol115/t2_basics_of_life/lesson2.htm#Carbohydrates
http://www.health.gov/dietaryguidelines/dga2005/healthieryou/html/chapter5.html
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