High Potent Muscle & Joint Rub

600mg CBD + Glucosamine

@PUREISCBD
www.pureiscbd.com

Available for own label or Pureis® branded supply.

CBD Skincare Market & Benefits
1.64 BILLION
The CBD skincare market share is
expected to increase by USD 1.64
billion from 2019 to 2024, and the
market’s growth momentum will
accelerate at a CAGR of 33%.¹
¹ Technavio, www.technavio.com/report/cbd-
skincare-market-size-industry-analysis&nowebp
The skincare benefits offered by
CBD is one of the key drivers
supporting the CBD skincare
market growth.
There is a lot of scientific literature
supporting the benefits of CBD for
skin making it a popular ingredient
in many skincare products.²
² Therapeutic Potential of Cannabidiol (CBD) for
Skin Health and Disorders - PMC (nih.gov)
High Potent Muscle & Joint Rub
600mg CBD + Glucosamine
Product Strength:
600mg of CBD per pack/pot
Pack Size:
50ml
Packaging:
Black glass pot with black plastic
lid & carton.
This clear rub produces a
warming effect on the skin.
Directions For Use:
1. Apply a moderate layer
to the desired area of We are also offering
your skin. a white generic tube
as an alternative
2. Rub until it feels cost-friendly
absorbed. packaging source.
3. Repeat this process as
often as necessary.
Packaging Prototype

High Potent Muscle & Joint Rub

600mg CBD + Glucosamine

Available for own label or Pureis® branded supply.

 Our product has been both clinically tested and User Trial approved. 80% of 113 participants

Clinical Studies advised the product relieved joint pain and 77% noted that it relieved muscle and strain
(full results of study on slide 9).

We are permitted to use the following claims due to the study success:
Claims on front of packaging:
High Potent Muscle & Joint Rub Instant Relief For Sore & Tired Muscles & Joints
600mg CBD + Glucosamine Soothes Inflamed Skin
Backed By Clinical Studies
Dermatologically & Sensitive Skin Approved
Non Medicated
For more insight into our claims and justification, please see slide 9.

The following ‘consumer quotes’ can be used on side or back of packaging & PR literature:
“Muscle pain completely disappeared.”
“More mobility due to less pain, I highly recommend this product, it’s amazing.”
“A warm feeling with relief from the throbbing pain.”
Please see full list of potential quotes which can be used on packaging on slides 10-11.
 Key Ingredients
Cannabidiol (CBD)
Can reduce excess sebum production & protect the skin from oxidative & Other Ingredients
environmental damage & has the potential to ease inflammation.
Candeillia Cera
N-Acetyl-D-Glucosamine
Improves skin tone Improves barrier function, reduces hyperpigmentation.
A vegetable wax coming from the leaves of the
North Mexican candelilla shrubs; used as a
Vitamin E (Tocopherol) thickening agent.
A powerful antioxidant, nourishes & protects the skin also considered an anti-
inflammatory agent for the skin. Silica
A trace element found in abundance in nature,
Hotflux® (Vanillyl Butyl Ether) used in the formulation as a thickening agent.
Stimulates micro circulation & imparts a warming sensation on the skin. Non
mutagenic, less irritating, safer than other warming agents.

Medium Chain Triglyceride (MCT) Oil;

Moisturising & hydrating, MCT oil can prevent moisture loss from the skin.

Cocoa Butter
Deeply hydrating; Cocoa butter can moisturize even the driest skin, containing a wealth Fragrance
of essential fatty acids & providing a source of antioxidants such as vitamin E &
polyphenols.

Grapeseed Oil Limonene

Sustainably sourced as a by-product of food waste this oil is great source of Citral
antioxidants polyphenols, barrier repair fatty acids & antioxidant, skin-protectant Cintronelllol
vitamin E; this oil is moisturising & nourishing, is incredibly gentle, making it perfect for Gernaiol
use by those with sensitive skin.
Each selected to lend a deeply relaxing
Cetearyl Alcohol aromatic notes to our product.
A multitasker ingredient that gives your skin a nice soft feel (emollient) & gives body to
creams & lotions.
Mandatory Text On Packaging
ON SECONDARY CONTAINER – CARTON

• All detail must be written in applicable language ( i.e.

ON PRIMARY CONTAINER – LABEL
English for marketing in UK and Ireland).
• RP details.
• All detail must be written in the applicable language
• Country of Origin.
(i.e. English for marketing in UK and Ireland).
• Batch number.
• RP details.
• Function of product (unless clear from presentation).
• Country of Origin.
‘Muscle Rub’ will suffice.
• Batch number.
• Minimum date of durability/ Period after opening.
• Function of product:
Recommended 12 months.
‘Muscle Rub’ will suffice. Non-Mandatory Desirable
Warning statements present:
• Minimum date of durability/ Period after opening. Text On Packaging
• For external use only. Do not take internally. Keep out
Recommended 12 months.
of reach of children.
• Avoid eye area. If irritation occurs, discontinue use.
• Nominal contents noted:
Warning statements present: • Directions for use
i.e. 50ml with ‘e’ symbol present.
• For external use only. Do not take internally.
• INCI (International nomenclature of Cosmetic • Supported claims – unique selling points
Keep out of reach of children.
Ingredients) list.
• Avoid eye area. If irritation occurs, discontinue use.
Vitis Vinifera (Grape) Seed Oil, Caprylic/Capric Triglyceride, Cetearyl
• Nominal contents noted: Alcohol, Candelilla Cera, Silica, Theobroma Cacao (Cocoa) Seed Butter, • Recyclable symbol & disposal instruction
Cannabidiol, Acetyl Glucosamine, Parfum (Fragrance), Vanillyl Butyl
i.e. 50ml with ‘e’ symbol present. Ether, Tocopherol, Limonene, inalool, Citral, Citronellol, Geraniol
 Cosmetic Regulatory Overview
Europe USA

• Since 2019 CBD has been included in the EU database of cosmetic

ingredients (CosIng) with synthetic CBD being the first to gain entry.
• The FDA regulates cosmetic products within the USA. However,
the law currently doesn't require FDA approval of cosmetics before
The CosIng database has listed the following functions for CBD:
being placed on the market.
• Antioxidant
• Anti-seborrheic
• For this reason, a cosmetic containing CBD may be
• Skin conditioning
manufactured, marketed, and sold to consumers without prior
• Skin protecting
explicit "clearance" from FDA, provided that the use of CBD, and
These functions suggest CBD could be used to protect the skin from
other ingredients used in the manufacture of cosmetics, is safe.
oxidative and environmental damage and ease inflammatory
reactions.
• FDA retains the authority to prohibit or restrict the use of certain
ingredients in the manufacture of cosmetics (a so-called "negative
We have compiled our Product Information File (PIF); the registration
list") by way of regulation, but, as of the date of this article,
documentation to support filing of a cosmetic application.
cannabis, hemp, and CBD do not currently appear on this list.
We hold a full PIF in line with current regulatory guidance.

Submission into EU Cosmetic Products Notification Portal (CPNP) is

complete.
Our product can be placed immediately on the market.
Our product is manufactured to the highest standards of cosmetic
good manufacturing practice, in adherence with global Quality
standards ISO 22716 and ISO 9001:2000 which comply fully with the
EU Cosmetic Safety Regulations 1223/2009/EC.
Rest of World
• Product Information File (PIF) is available for submission;
containing the relevant safety reports and manufacturing quality
documentation.
 Results of User Trial and Clinical Study
The results from our 113 subject User Trial and Clinical Study proved to be significantly higher than the benchmark at
the testing site. 70> deemed as a positive result, all the results below are in excess of 70%.
 Secondary Claims quoted by Subjects during User Trial –
These are real life quotes from Subjects in our User Trial.
“I could feel the pain subsiding
after a few minutes and got full
effect after around 10 minutes.”
“The benefit I enjoyed most of all
was being able to bend my knees
without pain. I also liked how
quickly it rubbed into the skin.”
“Helped relieve aches and pains
to painful joints whilst
moisturising the skin and leaving
it soft and supple, with a lovely
glow and a pleasant fragrance.”
Such claims can be used on back of the carton & PR material
“It was fantastic. I suffer really
badly with back problems and
osteoarthritis I needed
something quick working and I
certainly had my wish
fulfilled.”
“A warm feeling with relief
from the throbbing pain.”
“Skin felt softer and comforted,
like a hug in a jar.”
“My pain subsided and my
muscles felt relaxed and
soothed.”
“I suffer from rheumatoid arthritis
“After 10 minutes of using I felt
and get stiff and inflamed joints.
instant relief. After a few hours I
After using this the stiffness
subsided somewhat and the
reapplied. I found applying it just
before bed helped a lot as I was
redness and pain felt less
able to sleep better at night.”
intense.”
“More mobility due to less
“Best cream I’ve used in a while.
pain, I highly recommend this
While it was working on my skin I
product, it’s amazing.”
was happy and able to do a few
things pain free until I needed to
apply more. It’s a nice to have
that feeling it doesn’t happen “My joints felt a lot easier.”
often with my condition.”
“Soothing and pain free. Good
relief and as comparable to
“Muscle pain completely pharmacy products for the same
disappeared.” treatment.”
 Secondary Claims quoted by Subjects during User Trial –
These are real life quotes from Subjects in our User Trial.
“Felt soft and nourishing, so
enhanced the relief of pain.”
“Very impressed. It wasn’t over
powering with the smell, like
some are. The smell I thought was
really nice. It absorbed well into
the skin. I applied to my joints and
was really impressed after a short
period that I appeared to be pain
free for a good few hours. I would
definitely buy this.”
“The intensity of pain goes down
considerably.”
“Relief from pain.”
“I did not feel as achy and the pain
seemed to subside.”
Such claims can be used on back of the carton & PR material
“I used the cream on aching calves
“The stiffness and dull pain was
“Excellent product and gave me after running. My muscles felt
more manageable after 10 minutes
relief and improved my skin.” more relaxed – the tightness had
and after half an hour it was instant
gone and they felt warm even
relief, I could actually move the
though the area of skin wasn’t any
shoulder with no pain.”
warmer to the touch. My muscles
felt like they had a long hot bath.”
“I loved how quickly I felt relief
with a lovely warm feeling, it was
so helpful. Thank you I was able to “I have a painful knee, after
move around better.” applying this product my knee felt
“The relief on my back ache and
so much better.”
hand joints felt great and the
smell was nice too.”
“It helps relieve muscle pain by
“I found it to be perfect for my “An easing of the ache and less
calming, soothing, and relieving
needs and it has really helped sharp pain.”
with my joints.” tension. It also worked on aching
joints I found the whole
“Eased pain/inflammation to a experience to be calming and
level of comfort.” relaxing. So it helped me relax as
“Soothing, calming, relaxing and well.”
getting rid of tension.”
“Gentle easing of arthritic pain in
my hands.”
Non Medicated vs Medicated Topical Treatment For Pain Relief
With the rise in prevalence of arthritis and muscle strain,
surge in demand for topical pain relief products, drive the Global awareness of the opioid crisis, physicians are
growth of the global topical pain relief market. demanding alternative treatments. There is a growing
shift from conventional opioid treatment to non-opioid
For example, 100 million Americans live with some form of treatments.
chronic pain: The US topical pain relief market was valued at
$2,612 million in 2019 and is projected to reach $3,272 million
by 2027 at a CAGR of 3.7% from 2020 to 2027.³

Many people rely on medications, but they can come with a

high risk of side effects, drug interactions, and sometimes
misuse.

Growing consumer interest in a non-medicated solution to

provide relief short and long-term. With increased economic
financial strain and busy lifestyles, people are seeking
alternative non-medicated solutions rather than time and
expense of doctors visit and prescription costs.
³ www.alliedmarketresearch.com/us-topical-pain-relief-market
Non-Opioids segment holds a dominant position in
2019 and will continue to maintain the lead over the
forecast.³
Comparable Products PRODUCT

Voltarol • Voltarol Heat Patch.

• Up to 8 hours of pain relieving heat.

• Voltarol heat patch is available in two sachet packs.

VOLTAROL HEAT PATCH

• About: Non-medicated patch providing targeting pain relief up

to 8 hours. Continuous low level heat which stimulate heat
receptors to relieve pain, increases blood flow to relax
muscles, reduces muscle spams.

• The thin, self-adhesive, odourless patch provides effective

pain relief and muscle relaxation in a non-medicated, tablet-
free format.
Comparable Products PRODUCT

FlexiSEQ • FlexiSEQ Max Strength Gel.

• Available in 30g, 50g, and 100g pack sizes

FLEXISEQ MAX STRENGTH

• About: Drug Free & Clinically Proven - Unlike traditional pain

killers that temporarily relieve inflammation to mask pain,
FlexiSEQ Max Strength's drug free treatment lubricates the
cartilage in joints to help you regain pain-free mobility. It can
also be used alongside traditional pain medication with no
drug-to-drug interactions. In studies across almost 1,500
osteoarthritis patients, FlexiSEQ Max Strength showed
improvements in pain, joint stiffness and physical function, as
well as an impeccable safety profile.
 For first order, product can be delivered within 16 weeks
Product Timings of artwork approval.

For repeat order, pending packaging is held on site,

product can be manufactured and delivered within 8
weeks.

Product is manufactured in the UK.

Contact Information For more information, please contact:

Caroline Glynn Co-Founder & CSO
caroline@chanellemccoy.com

Chanelle Lady McCoy Founder & CEO

www.pureiscbd.com chanelle@chanellemccoy.com
www.chanellemccoyhealth.com