ACUTE

PROMYELOCYTIC
LEUKEMIA
by HematulogzzZ Group

Berondo I Kadayunan I Legario I Musa I Pascua

80-90% CURE RATE Approximately 6 cases per 10 million people per year

This funk Promyelocyte

thinks maturing into a real
white blood cell is a
laughing matter! He keeps
multiplying immature
forms, causing APL.

SIGNS AND SYMPTOMS

Bone marrow
Bone or joint pain problems Bleeding issues Anemia

Treatment Causes
APL has high cure rates with
specific combination
chemotherapy.
Specific Genetic Mutation
All-trans retinoic acid (ATRA)
medication helps to Not Inherited
differentiate abnormal cells Previous Cancers (Rare)
into mature ones.

Arsenic trioxide (ATO) may be

used in combination with
ATRA for high-risk APL or
relapsed cases.

RISK FACTORS
Smoking race and ethnicity

Aging Exposure to
Chemicals

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