Cholesleo 1elorolisn n to kg on, g

mmbwan i t y b, ud oinanl
tomonent de attls
- Ve.Ds

,-Sleord hoawok
tSbudwe

desnohybonmmfn súnnsermnhese
Catomg D,eC)
t
One -OHgp atgd þocrlon
ouble bemd bw s&&'c

A
HC

Phsawpkion
Chasse hycholyzed by ch: usluase
aL Ckinoporaud inb "rmallsabshed immuutesal t l
Chs eeied, &incosporaud imo chyomicaons
saachus blood shream Horoughlaerenls
eloduy Ch suachaa liw rough chyloeniton venrnans
U
Role or litinCh bolance
Xels Ch
Ch oomexta hebalte l&sues
Keveuse Ch tamspoxt via Hdl
- Chxemramt

T
e movo &mheus
lole shepakia ch
VIl to 1L (Teonset b exa-tepako firue)
pire extsekn ivndo brle
Btle acid symthaui Aexcdion in bile
 Melemy&ali Je mouo sumiteais helesdeol emlieuea
Jch ive extoa- e bali
Live Reveve beavnspost
Choo Cohbolfom
3oliaoy excyekon
bhdagenous lipopoolkin
(2TovOsmlkesis oCh
elylCoA+Aelylan Rele
sumihae (oA AcledcehlOAcelyl
GA CGA
SIEL GAHMG CoA Sypoase STEP 2
HMG CoA
siay ste-ivoe (1g/d) NADtHMGA(oAsuducase sTGPaRaleJimibingd sy
acbenal conex,ovanies Mevalenale (40)
3ATP
30pP Kinase0
ecarboxylase
STEP4
auahion
18Acekyl CoA+ lBAT? +16NADPH Isopootermlyoophosphate [5)
+402 ISomedase
mekiylally ophiocphale
)
Choleslerol +SCOtlo NePt | lamshe»qse STGPS
+8A +18Pi
Sage
dg PP Spenevgl pyopkosphale
ato7ms HMG (GA PR:Toamterase.
b)feormos acsCmlemedias Fame Pyoasphale (isc)
Usoaenoids) Saualene smhase.
c)6ispremidsfomosajualee Saualene (30t)
yualene 10 fom Ch Napeu.
Epoxtdase &yehse STE
lomosleol(3oc)

Cholesleol (23)
kequlshio, of Ch symikeetg
Reulnliom
on
Jnhikoas
Ch
ne
Srncileom

Innglalfon
Gilaragen HMGa lol edurhe
sains

Cempekltve ikler
ipovalev medttakion Kie
AMG COn
ATe
HMG Co
edushae educhue P)
(achfve Cnacke)
Cholesleol okein phosbhalase Glucagon
Isulio Imhibthoar i -0MP
Ch also Jes Lbl suuphor amhuis-(uplake)LTACAT shovage)
huin diüt1,sumtuis ted
*Exdion of Cholesenol:
vg.diek-300 mg/day exevetad Roough btle.
e movo Syrnlus-F00 m/day. J000/daY-500mg
Corvedad fo bile aude
Choleslesol

Ble a
Bile aids
Conjugakon
Blesal Potl vin (Gnlauohepalic ulotion,93-/)

-c8 *Cholesoroine. tveamept

pauds suzy dimg
Ciesalls mesi
badia bileauds
oglday) nhatin Jo.sg/dey(exdad mleces
 *Nusaional &havmauudual maama lor bualiq hauesuckolealestolerrnia
Reeauimg imake odintay snluuatad fal to <3ot caosiea
-uds ncluihfdo} LDLuuphox
UMdate inake oh dithy choleslool lo aooma/dty
it) Scomsmplion onúcous soluble, dúlasu tbre (1o-asg/a)
-impaua abco»píom o dielasy ch
SAabsonphno l&aieds
-Bacial umaliom. of 3oluble tbyes, susulls, in aho»tdaim Ja.
4Aakmay h silkass
HMG-CoA Rduase imilitos.
-Stalins.lovasltadainm)

bpr0