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Application of CEM
Application of CEM
Application of CEM
Uday K Khankhoje
4 Summary
Context
A 2017 study conducted by the National Institute of Pathology in India1
1
S. Malvia et al, “Epidemiology of breast cancer in Indian
women,” Asia-Pacific Journal of Clinical Oncology, 2017.
Uday K Khankhoje (EE @ IITM) Inverse Imaging 30 Mar 2019 3 / 17
Breast Cancer in India: a crisis
Context
A 2017 study conducted by the National Institute of Pathology in India1
1
S. Malvia et al, “Epidemiology of breast cancer in Indian
women,” Asia-Pacific Journal of Clinical Oncology, 2017.
Uday K Khankhoje (EE @ IITM) Inverse Imaging 30 Mar 2019 3 / 17
Can Microwave Technology Help?
Need methods that are: safe, inexpensive, quick, and non invasive
Microwave (RF) technology has the potential!
Processing
Use fields to solve mathematical problem to
get permittivity as a function of space, (r )
Look up tables of values prepared by
biologists to infer cancer
Diagnosis
Look up tables of values prepared by biologists
to infer cancer
4 Summary
∇ × E~ (r ) = −jωµ H(r
~ ), ~ ) = jω (r ) E~ (r ) + J(r
∇ × H(r ~ ) (1)
2
Single frequency (e jωt ), two-dimensions (x − y ), single polarization (Ez )
Maxwell’s equations that we know and love2 !
∇ × E~ (r ) = −jωµ H(r
~ ), ~ ) = jω (r ) E~ (r ) + J(r
∇ × H(r ~ ) (1)
2
Single frequency (e jωt ), two-dimensions (x − y ), single polarization (Ez )
Maxwell’s equations that we know and love2 !
∇ × E~ (r ) = −jωµ H(r
~ ), ~ ) = jω (r ) E~ (r ) + J(r
∇ × H(r ~ ) (1)
2
Single frequency (e jωt ), two-dimensions (x − y ), single polarization (Ez )
Maxwell’s equations that we know and love2 !
∇ × E~ (r ) = −jωµ H(r
~ ), ~ ) = jω (r ) E~ (r ) + J(r
∇ × H(r ~ ) (1)
2
Single frequency (e jωt ), two-dimensions (x − y ), single polarization (Ez )
Processing the Wave Equation into an Integral equation
E (r ) − k02 G (r , r 0 ) χ(r 0 ) E (r 0 ) dr 0 = Ei (r )
R
D
Scattered m
Discretize E (r ), χ(r
P) Nusing “pulse” basis field 𝑣𝑣𝑚𝑚
functions: E (r ) = n=1 un pn (r ). The new 𝝆𝝆𝒎𝒎𝒎𝒎
variables are un .
Internal n
For each r location on the grid, we will get field 𝑢𝑢𝑛𝑛 ,
a
contrast 𝜒𝜒𝑛𝑛 R
one equation in all N variables.
Cycle through all the N locations to get a 𝐷𝐷
N × N system of equations. Γ
4 Summary
When r ∈ D
u − GD Xu = e
‘State’ equation
Can solve for u
when X known
GD full rank: has
unique soln
When r ∈ D When r ∈ S
u − GD Xu = e s = GS Ux
‘State’ equation ‘Data’ equation
Can solve for u Can solve for x when
when X known U known
GD full rank: has GS under determined:
unique soln no unique soln
The solution with minimum `2 norm But solution with minimum `1 norm
has all entries non-zero → soln is has some entries zero → soln is
‘spread out’ in all variables sparse in higher dims
These kind of
solutions are studied
in the field of
Compressive
Sensing –
a new sub-field of
Signal Processing
since ∼2008
x
1 We will plot how ks − GS Uxk2 looks like, where x = 1
x2
(exact U is also calculated at each x)
2 We can look at linear (assuming U const) and
nonlinear approach (treating U as a fn of x)
Easy to arrive at the correct solution Many local minima along the way
4 Summary