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ඍඕඉඑඔඒඝඛගඡඖඉඓ#උඐඍඕඝඕඓ඘ඔ
Abstract
Collagen is the main component of connective tis-
sue – it represents 30% of total proteins in the animal
body. This protein occurs in a wide range of tissues,
e.g. in bone, skin, tendon, ligaments and cornea.
It provides structural integrity, strength, resistance
to tensile stress and elasticity. Due to its excellent
biocompatibility and controlled biodegradability, col-
lagen has found diverse application in the biomedical
field such as wound dressing, drug carrier and tissue
engineering. However, concerns about contamination
of mammalian collagen have stimulated the search
of another source of this biopolymer. Fish wastes
are thought to be an attractive and safe new source
of collagen. Fish and mammalian collagen differ in
physical and chemical properties.
The aim of this work was to examine the influence
of collagen extracted from different sources (rat tail
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and fish skin of Brama australis) on skin parameters
such as hydration, colour, pH and skin’s barrier quality.
The measurements had been taken on the skin surfa-
ce before as well as after application of the collagen
solutions.
The most harmful effect on skin parameters was
observed after application of rat tail collagen solution.
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the most favourable effect on the skin parameters.
The source of collagen has a significant influence
on its effectiveness. The greatest virtues for human
body were observed in the case of fish collagen
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Keywords: ILVK FROODJHQ %UDPD DXVWUDOLV (VR[
lucius, rat tail tendons, skin parameters
[Engineering of Biomaterials 146 (2018) 14-17]
Introduction
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