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Hospital Level Gastroenteritis Protocol 2016
Hospital Level Gastroenteritis Protocol 2016
REFERENCE: 16/4
ENQUIRIES: Dr EH Engelbrecht
For Attention:
District Managers: Metro District Health Services Sub-structures and Rural Districts
Circular: H……../2016
This protocol replaces 2014 protocol the standard management of children with acute gastroenteritis with
dehydration who have been admitted to hospital. It complements and is compatible with the acute
gastroenteritis protocols used in Primary Health Care and Emergency Centres. There is a summary document
and a detailed set of protocols and appropriate stationery. A background document, “Protocol for Hospital
Ward Level Management of Gastroenteritis among Children” updating the evidence and the strength of the
recommendations behind this protocol, is available on request and will be placed on the Department’s
website.
DR KEITH CLOETE
DATE:
23rd Floor, 4 Dorp Street, Cape Town, 8001 P O Box 2060, Cape Town, 8000
tel: +27 21 483 6865 fax: +27 21 483 3277 www.capegateway.go.v.za
Paediatric Clinical Protocol - Summary
PROTOCOL/GUIDELINE NAME:
GASTROENTERITIS IN CHILDREN: HOSPITAL LEVEL (PART 1)
This management protocol covers emergency and urgent care for acute gastroenteritis in children, and
provides guidelines for ongoing assessment and care of children for the first 48-72 hours of admission.
This protocol’s contents can be adapted for use in specific environments in the province, but the following
essentials of care must be followed:
• Rapid clinical assessment of circulation, hydration and co-morbidities such as severe malnutrition,
pneumonia, sepsis and HIV disease
• Immediate treatment of shock (intravascular dehydration) with pushes of parenteral (intravenous or
intra-osseous) isotonic fluids (normal saline) until the shock is treated or escalation of care is required
• Treatment of extravascular dehydration with Rapid rehydration over four hours by nasogastric
infusion of oral rehydration fluid where possible unless contraindicated
• IV fluid use confined to shocked, severely dehydrated, or complicated cases
• Regular re-assessment of hydration
• Continuing breast-feeding, and early re-introduction of other normal feeds
• Mineral and electrolyte supplementation
1) While the evidence that clinical criteria can reliably and consistently predict fluid requirements is
poor, distinguishing between degrees of extravascular dehydration would appear still to have value
in indicating how frequently a dehydrated child should be reviewed. In the light of this, degrees of
clinical dehydration categories are retained in this update. However in the light of this classification’s
uncertainty and the South Africa Hospital EML recommendations, a single volume per kilogram body
weight per hour is given for Rapid rehydration for a child with dehydration without shock; this can be
adjusted according to the initial response.
2) A reduced age to 2 months or 60 days of life for the special case of the small infant. This is consistent
with international literature on small babies’ risk profiles.
Rapid Rehydration
Oral rehydration solution (e.g. SOROL) NG or ½ Darrow’s Dextrose solution IV:
Dehydration without circulatory shock: All ages and weights: initial rate of 20 ml/kg/hr
Nil by mouth for 4 hours (except if breast feeding)
NB: Re-assess regularly especially if there are marked signs of dehydration. Consider repeating Rapid
Rehydration if still dehydrated at 4 hours.
Slower Rehydration
Oral rehydration solution (e.g. SOROL) NG or ½ Darrow’s Dextrose solution IV:
Dehydration without circulatory shock: All ages and weights: 10 ml/kg/hr (use higher volume if high stool
output).
NB: Re-assess regularly.
Feeding
Never stop breast feeding (unless there is another contraindication). ☻
Supplements
KCl (in all cases except those with shock)
Vitamin A dose x 1
Zinc for 10 days
Discharge on zinc, instruct parents in danger signs. Sugar salt solution and early follow up for weight check.
Advise an extra meal a day for a week after diarrhoea episode. Use the summary stamp in the Road to
Health Book to alert the PHC system to a child at risk.
Protocol/Guideline Name:
GASTROENTERITIS IN CHILDREN: HOSPITAL LEVEL (PART 1)
Date of issue: 01/03/2016
Adapted for provincial use from: Protocols designed by General Paediatricians in the Cape Town Metro
District 2006-2011 and Dr M Kunneke in Worcester Regional Hospital and Winelands/Overberg Districts
This management protocol covers emergency and urgent care for acute gastroenteritis in children, and
provides guidelines for ongoing assessment and care of children for the first 48-72 hours of admission. This
covers the period during which most children with gastroenteritis will be discharged from hospital.
• Emergency Medicine Gastroenteritis Protocol used in Emergency Centres under the Clinical
Governance of Emergency Medicine
• IMCI and ETAT-SA systems that are often used at PHC sites that may refer patients to hospitals for
ongoing care.
Other protocols in this series cover
• Electrolyte derangements
• Ongoing diarrhoea
The ☻symbol indicates that the evidence for the recommendation is strong (see accompanying Evidence
document).
This protocol’s contents can be adapted for use in specific environments in the province, but the following
essentials of care must be followed:
• Rapid clinical assessment of circulation, hydration and co-morbidities such as severe malnutrition,
pneumonia, sepsis and HIV disease
• Immediate treatment of shock (intravascular dehydration) with pushes of parenteral (intravenous or
intra-osseous) isotonic fluids (normal saline) until the shock is treated or escalation of care is required
(see page 2 – assessment, and page 4 and Appendix 3 – treatment)
• Treatment of extravascular dehydration with Rapid rehydration over four hours by nasogastric infusion of
oral rehydration fluid where possible unless contraindicated (see page 3 – assessment, and pages 5 & 6
– treatment)
• IV fluid use confined to shocked, severely dehydrated, or complicated cases
• Regular re-assessment of hydration (see page 8 - treatment, and Appendix 1 – assessment forms)
• Blood and other tests are usually NOT required (see page 3)
• Continuing breast-feeding, and early re-introduction of other normal feeds (see page 7)
• Mineral and electrolyte supplementation (see page 7)
This protocol is designed for use in Level 1 and Level 2 hospitals in areas under the clinical governance of
Family Medicine or Paediatrics.
PREAMBLE:
Most children who are admitted for acute gastroenteritis will be discharged within 48-72 hours having had no
complications. This protocol is designed to cover the period from presentation to discharge in these cases. A
follow-on protocol for cases of ongoing diarrhoea is available at most Level 2 hospitals.
Acute gastroenteritis is one of the commonest reasons for acute presentation in primary care and hospitals. It
is also a leading cause of death, usually from dehydration. Acute gastroenteritis is usually self-limiting with
water loss rapidly diminishing after 48 hours. Careful assessment, fluid therapy and regular re-assessment are
the keys to ensuring good outcomes.
Most importantly, fluid therapy must be initiated early – the longer one waits, the worse the outcome is likely
to be. So, essential history must be obtained while simultaneously assessing vital signs and hydration.
A. History
Essential history must be obtained while simultaneously assessing vital signs and hydration.
B. Examination
a) Assess airway and breathing
b) Always assess for shock next (intravascular dehydration) as it is a leading cause of death from
gastroenteritis:
If the child is shocked, urgent fluids are required. Go to Page 4 and institute therapy immediately
b. Other signs to look for: sunken fontanelle, dry mucous membranes, lack of tears when crying
The more obvious these signs are the more dehydrated the child is, the more it is essential to initiate
appropriate rehydration measures, and more frequently the child will need review.
C. Special investigations
These are NOT routine. ☻
If the child
Urine multiple parameter test strip (“dipstix”) is indicated in the following circumstances (remember risk of
false positive test strip result if urine is not fresh)
Other tests such as Chest X-ray are indicated if co-morbid disease is suspected.
Stool culture only if there is dysentery or suspected diarrhoea outbreak.
Children under 2 months of age with gastroenteritis usually warrant a ‘septic work-up’.
When no longer shocked, assess hydration and clinical condition and commence appropriate
continuing hydration regimen (page 5)
BOX C1: Dehydration without circulatory shock BOX C2: Dehydration without circulatory shock
Rapid Rehydration over 4 hours: Rehydration over 24 hours:
(a) ½ Darrow’s Dextrose solution IV or oral (a) ½ Darrow’s Dextrose solution IV or oral
rehydration solution (e.g. SOROL) NG at 20 rehydration solution (e.g. SOROL) NG:
ml/kg/hour [This volume is based on a All ages and weights: 10 ml/kg/hr (use a
composite of estimated rehydration, higher volume if high stool output). [This
maintenance and ongoing loss volume is based on a composite of
estimated rehydration, maintenance and
requirements over the first 4 hours.]
ongoing loss requirements over the first 4
(b) Glucose test strip (“dextrostix”)
hours.]
(c) Blood tests as above (Page 3)
(d) Nil by mouth for four hours unless breast (NB volumes in severe malnutrition are lower
feeding (refer to 10 Steps Protocol)
(e) Review in two hours (fluid intake,
(a) Glucose test strip (“dextrostix”)
hydration, blood results) and adjust fluids
(b) Blood tests as above (Page 3)
accordingly
(c) Nil by mouth for four hours unless breast
(f) After 4 hours, re-assess and go to Page 8
feeding
NB: If the child is still dehydrated at 4 hours, fluid (d) Review in two hours (fluid intake, hydration,
losses are likely to have been greater than blood results) and adjust fluids accordingly
previously assessed, so consider repeating the (e) After 4 hours, re-assess and go to Page 8
Rapid Rehydration regimen.
After the first 4 hours, do not withhold feeds (Feeding reduces the duration of diarrhoea in most cases).☻
In non-breastfed dehydrated children, feeds must be re-introduced after the first 4 hours of
rehydration.☻
Any child with diarrhoea asking for food or taking oral fluids can be fed.
for a total of 10 days (zinc reduces stool output and the chances of a repeat bout in the following three
months)
C) Vitamin A oral
All children who are admitted for gastroenteritis require a dose of Vitamin A:
NB: Do not give potassium chloride to children who have been shocked until the renal function test results
have been reviewed and it is considered appropriate to supplement potassium intake.
F: Other Problems
A) ELECTROLYTE ABNORMALITIES
- See protocol “Management of Electrolyte Abnormalities in Gastroenteritis”
- Ceftriaxone 50mg/kg/day IVI if toxic, rigors, delirium, leucopaenia, bradycardia or <3 months of age
C) SEVERE MALNUTRITION:
- Admit and treat according to 10 Steps Protocol
After the first four hours of rehydration, a full reassessment is required. The following principles apply to
prescribing fluid regimens in this phase:
Regular re-assessment
a) Reassessment of fluid requirements
If the child is still dehydrated, fluid losses are likely to have been greater than previously assessed,
so consider repeating the Rapid Rehydration regimen.
Alternative:
b. Maintenance volume: in most cases this can all be given as oral feeds (breast or formula)
- 0 – 3month 150ml/kg/d
Remember: Any child with diarrhoea asking for food or taking oral fluids can be fed.
c. Ongoing losses: 10-15ml/kg for each loose stool or vomit, preferably using oral rehydration
fluid orally. (This volume is a WHO standard.)
b) Do regular reassessments of fluid status and any acute complications
Clinical reassessments are required at least every four hours in the first 24 hours in hospital. Less
frequent assessment is required as diarrhoea and hydration improve. The hydration check form
(Appendix 1) or continuous assessment form (also Appendix 1) can be useful for these assessments.
Wherever possible, reduce IV and nasogastric fluids and increase oral fluids.
Most children do not require repeated blood tests (the kidneys, once perfused well, are very good at
retaining ions and correcting acid-base derangements). [But see “Management of Electrolyte
Abnormalities in Gastroenteritis” for more details.]
If the following criteria are fulfilled, the child will usually be ready for discharge:
Follow up:
a) Stools resolved: Hygiene advice (prevent another episode). Check SSS knowledge. No follow up
required. Zinc elemental oral (10mg/day <1 years of age, 20mg/day >1 year of age) for 10 days.
b) Stools still not fully formed: refer for weight and hydration check at local clinic. Advice re an extra meal a
day for a week (WHO standard). Stamp RTHB or RHTC with ‘Diarrhoea stamp’ (Appendix 2) and fill in any
necessary details, or write a short note including discharge weight and complications. Check SSS
knowledge. Zinc elemental oral (10mg/day <1 years of age, 20mg/day >1 year of age) for 10 days.
c) Other problems present: follow up in Primary Care service (e.g. nutrition clinic, local authority clinic)
unless specific hospital-level service is required (remember the cost of transport to the family).
d) Advise an extra meal a day for a week for every child after an episode of gastroenteritis to assist with
regaining list weight.
NB. Always ensure that the parent/caregiver
If after 48-72 hours of admission (2 full nights) there is no clear improvement, further testing and feed
manipulation may be required for possible lactose intolerance or systemic disease.
Use the protocol for ongoing diarrhoea and get senior advice.
HYDRATION CHECK
Weight g ↑ ↓
Vomiting Y N
Stools
Input Maintenance
Rehydration
OL
Intravascular status
LOC ↓ Normal
Extravascular status
Plan
TIME : AM / PM : : AM / PM : : AM / PM :
WEIGHT
TEMPERATURE
VOMITING
STOOLS
DRINKING ORS NOT / FAIR / WELL NOT / FAIR / WELL NOT / FAIR / WELL
DRINKING MILK / EATING NOT / FAIR / WELL NOT / FAIR / WELL NOT / FAIR / WELL
CIRCULATION/PULSE RATE / / /
DEHYDRATION NONE / PRESENT / MARKED NONE / PRESENT / MARKED NONE / PRESENT / MARKED
__________________ Hospital
Complications: ____________________________
_____________________________
Equipment:
1) Shock:
d. IV giving sets
2) Intravenous rehydration
b. IV giving sets
3) Naso-gastric rehydration
a. Size 8 NG tubes
Infusion controller machines for IV or enteral feeds are optional as in-line controllers can be used with the IV
giving sets for IV rehydration, or the Applix tubing for NG rehydration (Set up drip with ORS (Sorol) 200ml,
Applix Fresenius giving set, IV in-line controller (put in backwards) and attached to NG tube with the Fresenius
connector).
Pharmaceuticals:
8) Vitamin A capsules