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POISONING BY LUPINES (LUPINUS
LEUCOPHYLLUS; L. SERICEUS; L. CYANEUS).
These plants are commonly known by the names blue pea, blue
bean, and wild bean. They are coarse, silky-haired perennial herbs,
with blue flowers arranged in conspicuous terminal racemes, which
blossom in June and July, with long-stemmed leaves, which are
divided into from seven to eleven leaflets radiating from a common
point. The fruit is a hairy, several-seeded pod, and the seeds are
small and somewhat flattened.
As a rule these plants do not occur in the flat river bottoms. They
occur most abundantly on the foothills and mountain ranges at
moderate elevations.
During the season of 1900 the lupines in Montana began to bloom
about May 20th, and the first full pods were collected on June 5th.
Lupines are not very extensively eaten by sheep during the spring
and summer, except when they are unusually hungry or are being
driven from one range to another. Lupines are more often eaten by
sheep in summer on the mountain sides, and in the fall and early
winter after early frosts have opened the pods and the seeds have
fallen out. Lupine hay is greedily eaten by all kinds of stock during
the winter, and large quantities of this hay have been fed for the past
fifteen or twenty years. Lupine hay is cut in different years at dates
ranging from the 1st of July to the middle of September. When cut
during the first half of July the newly ripe pods, full of seeds, are
secured in the hay. When, however, the harvesting of lupine hay is
postponed until September, the pods become ripe and split open,
and the majority of seeds fall out. A striking variation in the quantity
of pods containing seeds is noted during different years. During
seasons in which May and June are wet the quantity of pods is
usually large. When, however, these months are dry only a few pods
are found on each plant, and a vast majority of the flowers fail to be
fertilised.
Dr. Wilcox has observed that sheep are especially fond of the pods
of various leguminous plants before they become mature and while
they are still in a succulent condition.
Dr. Wilcox saw a flock of sheep which while being driven from one
range to another, in a hungry condition, was allowed to feed upon an
area of lupines in a nearly ripe condition. Within two hours the sheep
manifested violent symptoms of poisoning, and ultimately 100 out of
the lot of 200 died. He afterwards saw many hundreds of fatal cases
in sheep and a number in horses, both from eating green lupines and
lupine hay.
As an experiment two sheep were given each 150 medium-sized
lupine pods (L. leucophyllus) which were entirely full of ripe seeds.
The sheep ate the pods readily. Both sheep became frenzied within
about forty-five minutes after feeding upon the lupine pods, and died
about one hour later. The symptoms in these cases were the same as
those observed in poisoning under natural conditions.
The symptoms of lupine poisoning are so well known in Europe
that chronic lupine poisoning has been given the name lupinosis. It
is characterised by loss of appetite, fever, dyspnœa, constipation, and
yellowness of the visible mucous membranes. Diarrhœa, sometimes
of a sanguinolent type, appears later. The urine becomes
albuminous, tinted with bile products or stained red by hæmoglobin,
and the head shows œdema. Death occurs in a few days. In America
the chronic form has not been observed. In cases of lupine poisoning
in Montana there was noted acute cerebral congestion, accompanied
with mental excitement. The sheep rushed about in different
directions, butting one another and other objects. The first stage of
frenzy was soon followed by a second stage, characterised by
pronounced irregularity of movement, spasms, and falling fits. In the
majority of cases death occurred in from one-half to one and one-
half hours. In extensive cases of lupine poisoning it was uniformly
observed that a number of the sheep lingered on from two to four
days before they died. The muscular convulsions resembled those
caused by strychnine. The excretion of the kidneys was much
increased and frequently was bloody. Post-mortem examinations of
sheep poisoned by lupines revealed conditions similar to those in
acute forms of loco disease, with the addition of a congested
condition of the kidneys.
Fig. 94.—Lupine (Lupinus
leucophyllus).

(From the Annual Report, U.S.A.


Department of Agriculture, 1900.)
Fig. 95.—Lupine (Lupinus leucophyllus) in
hay.

(From the Annual Report, U.S.A.


Department of Agriculture, 1900.)

No remedies have been tried in cases of poisoning from American


species of lupine, but it seems reasonable to suppose that potassium
permanganate would probably destroy the lupine alkaloids in the
stomach if administered promptly after the first signs of poisoning.
Experience and observation indicate that lupine hay is always
dangerous for sheep if cut at a time when the seeds are retained in
the hay. The evidence thus far collected regarding this matter
indicates that the seeds are the most poisonous part of the plant.

POISONING BY VETCHES (LATHYRUS SATIVUS): LATHYRISM.


In the horse this disease is due to feeding on grain containing the
seeds of vetches, but in the ox to eating the green portions of the
plants. Feeding has to be continued for at least a month to produce
accidents.
The earliest symptoms consist in suppression of milk secretion,
and somnolence. Nervous symptoms—from which alone the horse
suffers—soon make their appearance. The neuro-muscular system is
attacked. Interference with the nervous system is followed by inco-
ordination of movement, and later by paraplegia of the hind
quarters. Roaring is not noticeable, probably because the patients
rarely move rapidly.
The lesions have been little studied, but appear to consist in
congestion and infiltration of the meninges, cord, and roots of the
lumbo-sacral plexus.
Treatment. If the animals are paralysed, treatment is rarely of
value; otherwise it is sufficient to remove the cause and to administer
purgatives and diuretics, with the object of eliminating toxic
products. Recovery follows in three to four weeks.

Robinia pseudacacia.—The common locust tree is native in the


central and eastern parts of the United States, and is extensively
cultivated for ornamental purposes throughout the Union. The bark
and leaves contain a powerful poison, and persons have been killed
by eating these parts.
* Sophora secundiflora.—The beautiful bright-red beans of the
frijo-lillo, or coral bean of southern and western Texas contain a
powerfully poisonous alkaloid. The plant is said to have poisoned
stock in Texas and in northern Mexico.

LINACEÆ (FLAX FAMILY).

Linum rigidum.—The large-flowered yellow flax is reported


from Pecos Valley, Texas, as poisonous to sheep. An investigation
made by the Bureau of Animal Industry, U.S.A., showed that the
plant is poisonous.
ME
LIA
CE
Æ
(U
MB
REL
LA-
TR
EE
FA
MIL
Y).

*
Mel
ia
aze
dar
ach
.—
Fig. 96.—Caper spurge The Fig. 97.—Snow on the
(Euphorbia lathyris). a, Chi mountain (Euphorbia
Upper half of plant, one- nes marginata). a, Whole plant,
third natural size; b, seed e one-third natural size; b, seed
capsule, natural size. um capsule, natural size.
brel
la-
tree is much cultivated for ornament, and sometimes grows wild in
the South. A correspondent from Arizona stated that three of his
hogs were poisoned by eating the seeds, which were ignorantly
offered to them for food.

EUPHORBIACEÆ (SPURGE FAMILY).

Euphorbia.—There are many species of spurge native to the


United States, nearly all of which contain an acrid milky juice. Stock
generally avoid them, but cattle have been poisoned by drinking
water into which the plants have been thrown. The juice of E.
marginata and E. bicolour is used to some extent in Texas to brand
cattle, it being held to be superior to a red-hot iron for that purpose,
because screw worms will not infect the fresh scar and the spot heals
more readily.
* Jatropha stimulosa.—The seeds of the spurge nettle of the
Southern States are extremely poisonous. Stock avoid the plant on
account of its stinging hairs.
* Ricinus communis.—The
castor oil plant is quite
commonly cultivated in the
warmer portions of the United
States, and grows wild in the
South. The seeds have been
accidentally eaten by horses with
fatal effect, and they have been
strewn on pasture lands in the
North-West for the purpose of
killing sheep that were
trespassing thereon. A
Frenchman has discovered a
method of making cattle
immune to the effects of the
toxalbumin contained in the
seeds, so that they may be fed to
stock without causing any
apparent ill effect. A note on
poisoning by castor oil cake will
be found hereafter.
Fig. 98.—Castor oil plant
(Ricinus communis). BUXACEÆ (BOX FAMILY).

* Buxus sempervirens.—
The leaves of the common box, cultivated for hedges, are poisonous
to all kinds of stock.
ÆSCULACÆ (HORSE-
CHESTNUT FAMILY).

Æsculus californica,
California buckeye: Æ. glabra,
Ohio buckeye; fœtid buckeye:
Æ. hippocastanum, horse-
chestnut: Æ. pavia, red
buckeye.—The leaves and fruit
of these species are generally
regarded as poisonous to stock.
The fruit may be easily
converted into food by washing
and boiling. It is believed that a
small quantity of the
unprepared fruit of the
California buckeye will cause
cows to slip their young.

HYPERICACEÆ (ST. JOHN’S


WORT FAMILY).
Fig. 99.—Red chestnut (Æsculus
* Hypericum perforatum. pavia). a, Flowering branch; b,
—The common St. John’s wort seed—both two-ninths natural
is commonly believed to cause size.
disagreeable eruptions on cows’
udders and on the feet of white haired animals. This species and the
spotted St. John’s wort (H. maculatum) were brought into the
United States Bureau of Agriculture by Dr. G. W. Bready, from
Norwood, Maryland, who stated that five horses were poisoned in
May, 1898, by eating meadow hay which contained nearly 50 per
cent. of these plants. One horse died from the effects of the poison,
and two were killed to prevent their further suffering.

POISONING BY ST. JOHN’S WORT.


The ingestion of St. John’s
wort produces excitement
followed by dulness, interference
with vision and hearing, and by
visual hallucinations with a
tendency to lean backwards, the
front limbs remaining fixed in
position. The patient often sits
down on the hind quarters like a
dog.

APIACEÆ (CARROT FAMILY).

* Cicuta maculata. This is


the water hemlock (spotted
hemlock; beaver poison;
cowbane), which grows most
abundantly throughout the
United States. It is one of the best
known poisonous plants. Stock
Fig. 100.—Water hemlock are not infrequently killed by
(Cicuta maculata), showing eating the fleshy roots or hay
section of spindle-shaped roots with which the plants are mixed.
and lower stem, the leaves, * Cicuta vagans.—Cattle are
flowers, and fruit, one-half frequently killed in Oregon and
natural size; also fruit and cross- Washington by eating the large
section of seed, enlarged five fleshy rootstocks which have
times. been washed, frozen, or dug out
of the soil, or by drinking water
in marshes where the roots have
been trampled upon. The roots of the other species of Cicuta are
undoubtedly poisonous, but cases have been reported against one
other species only, namely, C. bolanderi. It grows in marshy land in
California.
* Conium maculatum.—The well-known poison hemlock, or
spotted hemlock of Europe, is an introduced weed not uncommon in
the north-eastern section of the United States and in California. The
pla
nt
is
gen
era
lly
avo
ide
d
by
sto
ck
on
acc
ou
nt
of
its
bad
odo
ur,
Fig. 101.—Oregon water but
ani Fig. 102.—Poison hemlock
hemlock (Cicuta vagans). a,
Plant with leaves, one-sixth ma (Conium maculatum), showing
ls upper portion of plant with
natural size; b and b′, flowers and seed, one-third
rootstock and horizontal hav
e natural size.
roots, showing section, half-
size; c, terminal leaflets, bee
one-sixth natural size; d, n killed by eating it in the fresh state.
flowering spray, full size. Since the poisonous constituent is
volatile, the dry plants are not so
dangerous.

POISONING BY HEMLOCK AND WILD CHERVIL (ANTHRISCUS


SYLVESTRIS).

Poisoning only results from ingestion of the green plants. It is


characterised by salivation, nausea, dyspnœa, generalised trembling
and vertigo,
paraplegia,
and
symptoms
of gastro-
enteritis.

POISONIN
G BY
FENNEL.

This
disease,
seen in
Algeria,
and
recently
studied by
Bremond
and Bojoly,
need only
Fig. 103.— be Fig. 104.—Broad-leaf laurel
Narrow-leaf mentioned. (Kalmia latifolia). a, Flowering
laurel (Kalmia The spray, one-third natural size; b,
angustifolia), information vertical section of flower showing
showing at present peculiar attachment of stamens,
flowering available is natural size; c, fruiting capsules,
branch, one- indefinite, natural size.
third natural and the
size. symptoms
so closely resemble those of Texas fever that
there seems a possibility of confusion having arisen.
The lesions are those of hæmorrhagic gastro-enteritis.
Treatment consists in giving tannin, opium, and emollients.
Oxypolis rigidus.—The cowbane
is natural in swamps throughout the
eastern half of the United States. The
leaves and roots are reputed to be
poisonous to cattle.
Sium cicutæfolium.—The leaves
of the hemlock water parsnip, which
is more or less common throughout
the United States, are said to be
poisonous to stock.

ERICAEÆ (HEATH FAMILY).

Andromeda polifolia.—The wild


rosemary, or moorwort, is a plant
native to the northern regions of
Europe, Asia, and America, entering
the United States only in the extreme
north-east. The leaves, which have
been eaten by sheep with fatal effect,
contain a narcotic poison known as Fig. 105.—Branch ivy
andromedotoxin. The plant is not (Leucothoë catesbæi). a,
very dangerous in its native habitat, Flowering branch; b, fruiting
because it grows in bogs which are capsules.
inaccessible to stock.
* Azalea occidentalis.—The
California azalea is very much dreaded by sheep men who drive their
flocks into the southern Sierras for pasture. Investigation has shown
that the leaves contain a poisonous substance.
* Kalmia angustifolia.—The narrow-leaf laurel is abundant in
the north-eastern section of the United States, where it is also well
known as sheep laurel and lamb-kill. The leaves contain
andromedotoxin, and sheep and calves are frequently poisoned by
eating them.
* Kalmia latifolia.—The broad-leaf laurel is native throughout
the greater part of the eastern half of the United States, and is known
by a great variety of common names, the most important of which
are laurel and ivy. The latter name is most commonly used south of
Maryland. Scores of cattle and sheep are poisoned annually by eating
the plant. It is probably the most dangerous of all the shrubs
belonging to the heath family.

Fig. 106.—Stagger bush (Pieris Fig. 107.—Great laurel


mariana), showing flowering (Rhododendron maximum).
branch, one-third natural size. a, Flowering branch; b,
fruiting capsules—both one-
* Leucothoë catesbæi.—This is third natural size.
the branch ivy, hemlock, or calf-kill,
of the Allegheny Mountains. It is well known in that region to be fatal
to all kinds of stock.
* Leucothoë racemosa.—The swamp Leucothoë of the Atlantic
and Gulf States has been reported from New Jersey as especially fatal
to calves.
* Pieris mariana.—The stagger bush of the Atlantic Coast
region, Tennessee, and Arkansas is commonly known to be
poisonous to calves and to sheep. The name stagger bush was applied
to the shrub on account of the peculiar intoxicating effect of the
leaves.
* Rhododendron californicum.—The California
rhododendron is native on the Pacific Slope from San Francisco to
British Columbia. The plant is reported from Oregon as poisonous to
sheep. It is quite probable that the leaves contain andromedotoxin,
but they have not been tested.
* Rhododendron maximum.—The great
laurel (rosebay; mountain laurel; rhododendron) is
a large evergreen bush or small tree which is quite
commonly cultivated for ornament, and is found
native in the Allegheny Mountains. The leaves
contain andromedotoxin, and they are occasionally
eaten by stock with fatal effect.

PRIMULACEÆ (PRIMROSE FAMILY).

Anagallis arvensis.—The pimpernel is a


European plant which has obtained a specially
strong foothold in California, where it grows
luxuriantly and is sometimes known as poison
weed. It is suspected of having caused the death of
a horse at Santa Ana. Chemists have isolated a
powerfully poisonous oil and a strongly active
ferment from the plant.

OLEACEÆ (OLIVE FAMILY).


Fig. 108.—
Milkweed
Ligustrum vulgare.—The privet, or prim, is a (Asclepias
garden shrub, introduced from Europe and Asia, eriocarpa),
which is much used for hedges, and has escaped one-sixth
from cultivation in western New York and natural size.
southward to North Carolina. Accidents have been
occasioned in children both by the fruit and the
leaves. The plant is to be suspected in cases of poisoning in animals.

APOCYNACEÆ (DOGBANE FAMILY).

Apocynum androsæmifolium, spreading dogbane: A.


cannabinum, Indian hemp.—These plants are generally distributed
throughout the United States. Stock generally avoid them in pasture
fields on account of their acrid milky juice. When dry they are not so
poisonous as when in the fresh state.
Nerium oleander.—The oleander is a common house plant
throughout a large portion of the United States. It grows freely out of
doors in the Southern and Western States, and has probably escaped
from cultivation in some places. It grows wild in northern Mexico.
The leaves are well known to be most powerfully poisonous, and
stock are occasionally killed by eating them.

ASCLEPIADACEÆ (MILKWEED FAMILY).

* Asclepias eriocarpa.—This is the plant with broad mullein-


like leaves which is known as milkweed in California. Several
authentic accounts of the poisoning of sheep have been secured
against the plant in Mendocino County. It is especially feared on very
warm days by sheep men when they are compelled to drive their
flocks through dry, barren valleys. It sometimes grows on cultivated
land, and is cut with hay.
* Asclepias syriaca.—This is the common milkweed, or
silkweed, of the north-eastern quarter of the United States.
Experiments show that the milky juice so abundant in all parts of the
plant is very acrid and poisonous. It is listed among the poisonous
plants of Europe.

SOLANACEÆ (POTATO FAMILY).


* Datura stramonium: D.
tatula.—These two species very
closely resemble each other, and
are most commonly known in the
United States by the name of
jimson weed. They are European
plants which have become weeds
in waste grounds and about
dwellings throughout the greater
portion of the country. One or
two instances are recorded in
which cattle have been poisoned
by eating hay containing the
young leaves.
* Hyoscyamus niger.—The
black henbane is an ill-smelling
plant, a native of Europe, now
naturalised in Michigan, and
from New York northward. One
or two cases are recorded in
European literature in which
stock have been poisoned by
Fig. 109.—Jimson weed (Datura eating the plant of their own
stramonium). a, Flowering accord, but there is very little
spray; b, fruiting capsule—both danger from it, on account of its
one-third natural size. ill odour and harsh texture.
* Nicotiana tabacum.—This
is the tobacco most commonly cultivated in the United States. It is
native to South America and has escaped from cultivation to some
extent in the Southern States. According to some authorities stock
are not always disposed to shun this plant on account of its
characteristic ill odour and taste, but, on the contrary, will eat a
small amount of the leaves with apparent relish, especially when they
are somewhat fresh. Stock have, however, been poisoned by eating
leaves which were placed within their reach to dry, and also by eating
food contaminated with the juice of the leaves. Considerable
precaution should be used in applying tobacco juice to fresh cuts or
bruises in stock, as the poison is easily absorbed into the system and
may
prove
fatal.
There
are
several
native
species
of
tobacco
in the
western
half of
the
United
States,
all of
which
are
undoubt
edly
Fig. 110.—Bittersweet poisonou
s if eaten Fig. 111.—Black
(Solanum dulcamara). a, nightshade (Solanum
Flowering spray; b, fruit— even in
moderat nigrum), one-third
both one-third natural size. natural size.
e
quantity.

TOBACCO POISONING.

Tobacco poisoning may be produced by baths or lotions containing


tobacco juice, which is often used as a parasiticide. The ingestion of
tobacco leaves in forage may also produce poisoning. Doses of 1
ounce in the goat and 10 ounces in the ox are toxic.
The symptoms consist in salivation, vomiting, nausea, diarrhœa,
cardiac palpitation and dyspnœa.
The lesions are those of gastro-enteritis with cerebral congestion.
Treatment consists in giving
tannin, black coffee, etc.

Solanum dulcamara.—The
bittersweet, or climbing nightshade, is
a European weed, now introduced in
the north-eastern quarter of the
United States. The leaves are
suspected of being poisonous to stock.
* Solanum nigrum.—The black
nightshade (common nightshade;
garden nightshade) is a common weed
in cultivated fields throughout the
greater portion of the United States.
Cattle seldom eat the plant, but a few
cases of poisoning are recorded for
calves, sheep, goats, and swine.
* Solanum triflorum.—The
spreading nightshade is a native of the
Great Plains (United States), and also
Fig. 112.—Spreading a common garden weed from Arizona
nightshade (Solanum and Texas to British America.
triflorum), one-third Complaints of the poisoning of cattle
natural size. by this plant have been sent to the
Department of Agriculture from
Nebraska. Experiments show that the
berries are poisonous.
Solanum tuberosum.—The small, immature tubers of the
common cultivated potato and those that have turned green from
exposure to the sun are slightly poisonous. The green fruit and the
white sprouts from mature potatoes are likewise poisonous. In all of
these cases the deleterious substance may be removed or destroyed
by thorough boiling.

SCROPHULARIACEÆ (FIGWORT FAMILY).


Digitalis purpurea.—The purple
foxglove is a common garden plant
which has sparingly escaped from
cultivation and is naturalised to some
extent on Cape Breton Island. Horses
are occasionally poisoned in Europe
by nipping the plants from gardens or
by eating hay contaminated with it.
Gerardia tenuifolia.—The
slender gerardia is native to the
eastern half of the United States, and
has been specially reported as
poisonous to sheep and to calves in
the Southern States.
Gratiola officinalis.—The hedge
hyssop of the Southern States
contains an acrid poison. The same
plant grows in Europe, and is there
regarded as poisonous to stock.
Pedicularis.—The plants of this
genus are commonly called lousewort.
In Europe several species are Fig. 113.—Sneezeweed
suspected of being slightly poisonous (Helenium autumnale),
to stock. One of these, P. palustris, one-third natural size.
occurs in Labrador, and there are over
thirty species native to the United
States, largely Western. They should all be suspected of being
poisonous.

CAMPANULACEÆ (BELL-FLOWER FAMILY).

Lobelia inflata, Indian tobacco: L. kalmii, brook lobelia: L.


spicata, pale-spiked lobelia: L. syphilitica, great lobelia.—All of
the species in this genus contain an acrid and usually milky juice,
and are poisonous. None has been specially reported as poisonous to
stock, but the above-named species are to be suspected, because they
frequently occur in grass and are sometimes found in meadow hay.
AMBROSIACEÆ (RAGWEED FAMILY).

Xanthium canadense.—The young seedlings of the American


cocklebur are reported from Texas as being rapidly fatal to hogs.
Xanthium spinosum.—The spiny clotbur is suspected of being
poisonous, but few cases have been definitely recorded against it.
The seeds apparently contain a toxic compound.
Xanthium strumarium.—The young seedlings of the broad
cocklebur are reported from Georgia as being fatal to hogs.
Experiments seem to show that the seed is poisonous.

CARDUACEÆ (THISTLE FAMILY).

* Helenium autumnale.—Sneezeweed (sneezewort; autumn


sneezeweed; stagger weed; false sunflower) is found throughout the
greater portion of the United States, being most abundant in the
Southern and Eastern States. Sheep, cattle and horses that are
unfamiliar with the plant are often poisoned by it when driven to
localities where it is abundant. Stock avoid it, as a rule, but it is
claimed that they sometimes develop a taste for the plant, and are
killed quickly by eating it in large quantity.
Senecio jacobæa.—The tansy ragwort, or stagger wort, is a
European plant which grows as a weed in ballast about New York
and Philadelphia. Farther north, in Nova Scotia, it has become
extensively naturalised, and it is there regarded by stock men as
poisonous. It is interesting to note that S. guadalensis of Mexico is
also considered fatal to stock.

COLCHICUM POISONING.

Fodder of bad quality often contains leaves, flowers, and


particularly seeds of colchicum, which produce nausea, vomiting,
colic and diarrhœa. The colchicine acts particularly on the kidney
and heart, producing specific disturbance, indicated by hæmaturia,
polyuria, and cardiac palpitation, with lowering of the body
temperature.

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