Course Title: Basic Biostatistics

L T P/S SW/FW TOTAL

Course Code: BIOT 331 Credit Units: 02 CREDIT
UNITS
2 0 0 0 2

Course Objectives: The course aims to develop competency and expertise in the application of statistical methods applied to biological data obtained in
experimental techniques, methodology and the safe laboratory practice.

Pre-requisites: General
Student Learning Outcomes:

At the end of the course the learner shall be able to:

 Explain calculate and interpret descriptive statistics including scales of measurement, frequency distributions, measure of central tendency, measure of
dispersion.
 Understand the basic concepts of inferential statistics including probability, confidence intervals and hypothesis testing.
 Know when and how to apply common parametric statistical tests.

Course Contents/Syllabus- Theory:

Weightage (%)
Module I 10
Statistics and Biostatistics: Preliminary concepts. Measures of Central Tendency: Mean, Median, Mode, Measures of
Dispersion: Range, Standard deviation, Variance,coefiicient of variation Various types of graphs

Module II
Probability: Random Experiments, Trial and Event, Sample Space, Mutually Exclusive or Disjoint Events, Mutually 20
Exhaustive Events, Equally Probable Events, Complementary Event, Classical definition of Probability, Statistical
definition of Probability, Axiomatic definition of Probability, Addition theorem, Multiplication theorem, Conditional
Probability, Bayes’ Theorem.

20
Module III
Correlation, Types of Correlation, Simple Correlation Coefficient for ungrouped data, Properties and Interpretation of
Correlation Coefficient, Coefficient of determination, Scatter diagram, Standard Error, Probable error of Correlation
Coefficient.Spearman Rank correlation, Some examples.

10
Module IV
Regression lines and Regression Coefficients, Properties of Regression Coefficients, Some examples.

Module V 15

Discrete Distribution
Binomial and Poisson distribution
Continuous Distribution
Normal Distribution, Properties of Normal distribution

Module VI 25

Parameter, Statistic, Null hypothesis, Alternative hypothesis, Critical region, Type1 Error, Type 11 Error, Level of
significance, P-value and its applications.
Test of Significance for Small samples: One sample t-test, Unpaired t test, Paired t-test
Chi-square Test: Test of goodness of fit, Test of Independence of attributes, Degrees of freedom for Chi square test,
Coefficient of contingency.
F test for equality of Population variances, Analysis of Variance: One way with examples
Pedagogy for Course Delivery:
Lectures: 26
Tutorial: 0
Presentation/ Seminar: 2
Class Test: 02
Total: 30

Lab/ Practical details, if applicable: NA

Tutorial:
Practical:
Class test :
Total:

Assessment/ Examination Scheme:

Theory L/T (%) Lab/Practical/Studio (%) Total

100 NA 100

Theory Assessment (L&T):

Components (Drop Class Test 1 Home Assignment Presentation/ Attendance

down) Seminar End Term
Examination

Weightage (%) 15 10 - 5
70

Lab/ Practical/ Studio Assessment: NA

Continuous Assessment/Internal
Assessment
Components Performance Lab viva Attendance Lab Performance Viva Total
(Drop down record record

Weightage
(%)

Text & References:

Text:

 Introduction to Biostatistics, Ronald N. Forthfer and Eun Sun Lee, Publisher: Elsevier.
 Statistical Methodology, S.P. Gupta, Publisher: S. Chand & Co.
 Fundamentals of Statistics, S.C. Gupta. Publisher: S.Chand & Co.

References:

 Biostatistics: A manual of Statistical Methodology for use in Health, Nutrition and Anthropology, K. Visweswara Rao. Publisher: Jaypee Brothers
Biostatistics: A foundation for analysis in the Health Sciences, W.W. Daniel, Publisher: John Wiley and Sons
 Fundamentals of Mathematical Statistics, S.C. Gupta and V.K. Kapoor, Publisher: S.Chand & Co.
 Statistical Analysis, Kaushal, T.L. Publisher: Kalyani Publishers
 Statistical Methods, Potri, D. Kalyani Publishers.
 Mathematical Statistics, H.C. Saxena, and V.K. Kapoor: S. Chand & Company
 Biostatistics, P.N. Arora and P.K. Malhan, Publisher: Himalaya Publishing House.