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Respiratory: Anatomy + Physiology
Respiratory: Anatomy + Physiology
Part I:
Anatomy + Physiology
Respiratory System Anatomy
Gas exchange
The delivery of oxygen from the lungs to the bloodstream, and the elimination of
carbon dioxide from the bloodstream to the lungs. Occurs in the alveoli through
passive diffusion.
Terminology
● Ventilation
○ Air movement in and out of the lungs
● Oxygenation
○ Oxygen in the bloodstream
● Perfusion
○ Oxygen in the tissues
Nasal Cannula
High-flow
Venturi mask High flow nasal cannula
Non-Invasive Ventilation
Invasive Ventilation
● Endotracheal tube
● Tracheostomy
● Mechanical ventilator
Ventilator Alarms
High Pressure Alarms Low Pressure Alarms
Pressure in the circuit is too high. Pressure in the circuit is too low.
Causes: Causes:
Client coughing Tubing is disconnected
Gagging Loose connections
Bronchospasm Leak
Fighting the ventilator Extubation
ETT occlusion Cuffed ETT or trach is deflated
Kink in the tubing Poorly fitting CPAP/BiPAP mask
Increased secretions
Thick secretions
Water in ventilator circuit
Endotracheal
Tube
What is an endotracheal tube (ETT)?
● Invasive, artificial airway used when the client is unable to protect their own
airway.
Trach Care
● Infection prevention is key!
○ The natural defenses of the nose and mouth are bypassed - higher risk for infection
○ Daily trach care - inpatient, this is a sterile procedure.
● Position: Fowler’s or semi-Fowler’s
● Perform hand hygiene, don clean gloves.
● Remove soiled dressing. Don sterile gloves.
● Clean the tracheostomy site
○ Use sterile applicators or gauze dressings moistened with normal saline.
■ 1:1 NS and Hydrogen peroxide is used with some clients
○ Use each applicator/gauze once, then discard.
○ Dry client’s skin
● Apply new sterile dressing
● Change tracheostomy ties
● Check tightness - ensure 1 finger can fit underneath
Suctioning
● Only suction to the pre measured depth
○ Suctioning too deep can cause damage or cause laryngospasm
○ Don’t suction longer than 10 seconds
● Some clients may need pre-oxygenated with 100% FiO2
Safety
● You must keep two back up trachs at the bedside incase of emergency
○ 1 of same size
○ 1 a half size smaller
● If the trach comes out, first try to insert the back up of the same size
● If unsuccessful, try to insert the half size smaller
Chest Tubes
Part II:
Respiratory Pharmacology
Bronchodilators
● Albuterol
● Theophylline
● Terbutaline
● Levosalbutamol
● Ipratropium
Albuterol
Therapeutic class: Bronchodilator; short acting beta 2 agonist
Nursing Considerations:
• Mechanism of action: Blocks beta 2 adrenergic receptors in the respiratory system to cause
bronchodilation by inhibiting the release of hypersensitivity reaction products from mast cells.
• Indications:
• Rescue/Relief and maintenance drug for wheezing, SOB, and coughing caused by asthma.
• Nursing considerations:
• SE: shakiness, jitteriness, dizziness, drowsiness, sleep disturbances, weakness, headache,
nausea, vomiting tachycardia, hypertension, hyperglycemia. CNS overstimulation.
• Assess HR, BP, EKG, blood glucose
• Can be given orally, SC, or by inhaler. 4-6 hour duration. More SE with oral administration
because it requires higher dosage.
• Teach proper inhaler use
Inhalers
● Hold with mouthpiece down. DO NOT hold
upside down
● Seal lips tightly around mouthpiece.
● Inhale through the mouth slowly
● Press down on inhaler one time. One breath in
= one puff of medication
● Continue inhaling while medication is
dispensed (will likely feel cold) - breathe
slowly and as deeply as possible.
● Shake prior to use
Spacer
● Connects to the mouthpiece
of the inhaler so the
nebulized medication goes
into the spacer first.
● Allows the client to more
easily breathe in the
medication - timing of the
breath is less important
● Wastes less medication
● Common in pediatrics
Practice Question
Which of the following comments by the client reflects an understanding of the proper use of a
metered-dose inhaler?
Misc. Respiratory
● Montelukast
○ Leukotriene modifier
● Guaifenesin
○ Expectorant
● Acetylcysteine
○ Mucolytic
● Pseudoephedrine, phenylephrine
○ Decongestant
● Antitussives
○ Dextromethorphan
○ Codeine
Steroids
● Betamethasone
● Dexamethasone
● Cortisone
● Methylprednisolone
Methylprednisolone
Therapeutic class: Corticosteroids
Nursing Considerations:
Diphenhydramine
Therapeutic class: Antihistamine
Nursing Considerations:
Asthma
● A respiratory condition marked by spasms in the bronchi of the lungs, causing
difficulty in breathing.
● Chronic inflammation of bronchi and bronchioles.
● Excess mucus.
● Result of an allergic reaction or hypersensitivity.
Pathophysiology
1. Airway is abnormally reactive - heightened sensitivity
2. Trigger causes a response
3. Inflammation and excess mucus production occur
4. Bronchospasm decreases the airway diameter
5. Airflow becomes obstructed
After many asthma reactions, airway remodeling occurs which causes scarring
and changes to lung tissue.
Triggers
A - Allergens
S - Sport / Smoking
T - Temperature change
H - Hazards
M - Microbes
A - Anxiety
Assessment
● Shortness of breath
● Unable to speak
○ Evaluate how many words they can say before taking a breath
● Cough
● Increased work of breathing
○ Retractions
○ Tracheal tug
○ Head bobbing
● Wheeze
● Prolonged expiration
● Can’t hear any breath sounds? Complete obstruction.
Classifications
● Viral
○ Caused by viruses such as RSV, adenovirus, and influenza
● Bacteria
● Fungal
● Chemical irritation
● Aspiration
○ When foreign bodies such as food and secretions enter the lungs
○ Cause inflammation and infection leading to pneumonia
Diagnosis
● Chest x-ray
○ “Patchy infiltrates”
● Sputum culture
○ Will identify a bacterial source
Assessment
● High fever
● Cough
● Tachypnea
● Crackles
● Chest pain
● Work of breathing
○ Retractions
○ Tracheal tug
○ Nasal Flaring
○ Grunting
○ Head bobbing
Treatment
● Maintain airway ● Chest physiotherapy
○ Suction
● Antipyretics
○ Monitor SpO2
● Monitor breathing ● Analgesia
○ Assess for increased work of breathing ● Cough suppressant
○ Provide support as needed ● Expectorants
○ Humidified oxygen ● Antibiotics if bacterial
● Maintain circulation ● Isolation
○ Monitor for dehydration
○ IVF if unable to tolerate PO
NCLEX Question
The nurse is reviewing the discharge teaching with a family who will be taking their
12 year old diagnosed with pneumonia home today. Which of the following points
should they review? Select all that apply.
B is correct. It is very important to teach parents to administer the full course of antibiotics, even if their child starts to feel
better. If the parents stop administering antibiotics part of the way through the course, they will be promoting antibiotic
resistance and the chance that the infection could return.
C is incorrect. The parents do not need to call the pediatrician if there is tan sputum when the child coughs. This is a
normal finding of pneumonia and should be expected. If there is a new onset of green sputum, this could indicate the
development of a bacterial pneumonia and the need to call the pediatrician.
D is incorrect. While Ibuprofen does have some antipyretic properties, it is not the best choice of medication to treat a
fever. If the child has a temperature of 100 F, the parents should be educated to administer acetaminophen, which is the
first choice for an antipyretic medication.
E is correct. Any signs of increased work of breathing (tachypnea, retractions, accessory muscle use, grunting, etc.) need
to be reported and assessed by a provider immediately
Reference: Hockenberry, M., Wilson, D. & Rodgers, C. (2017). Wong’s essentials of Pediatric Nursing (10th ed.) St. Louis, MO: Elsevier Limited.
Subject: Pediatric
Lesson: Respiratory
● Sepsis
● Trauma
● Burns
● Aspiration pneumonia
● Overdose
● Near drowning
Source: Creative Commons: Altaf Gauhar Haji, Shekhar Sharma, DK Vijaykumar and Jerry Paul., Transfusion-related acute lung injury chest X-ray, CC BY 2.0
Assessment
● Chest x-ray
○ Diffuse bilateral infiltrates
○ “Whited-out”
● Hypoxemia
○ Pale
○ Cool
○ Dusky
○ Mottled
○ Low SpO2
Treatment
TREAT THE UNDERLYING CONDITION
Pneumothorax
● Air or fluid collects in the
pleural space
● Presses down on the lung.
Causes
● Spontaneous
○ Occurs due to a disease process
● Traumatic
○ Blunt
○ Penetrating
○ Complication of a procedure
Assessment
● Shortness of breath
● Chest pain
● Desaturation
● Hypotension
● Tachycardia
● Check that the trachea is midline…
Treatment
● Needle decompression
● Chest tube
→ When air continues to enter the lungs, leak into the pleural space, and then
can’t leave!
→ It pushes on the lungs, trachea, and heart and starts shifting them to one side.
Pulmonary Embolism
What is a Pulmonary Embolism?
● Life threatening blood clot in the lungs
● Can be caused by an embolism from a vein entering the lung, or a clot during
surgery.
● The clot decreases perfusion causing hypoxemia
● Can lead to right heart failure if untreated.
Assessment
● Anxiety
● Dyspnea
● Chest pain
● Hypoxemia
● Rales
● Diaphoresis
● Hemoptysis
Treatment and Nursing Interventions
● Oxygen administration
● Positioning
○ High fowler’s
○ Promotes maximum lung expansion and assists with breathing
● Anticoagulants
● Thrombolytics
Answer: E
Choice E is correct. During a pulmonary embolism, circulation in the pulmonary bed is altered,
thus affecting the oxygenation of the client. Oxygen should be started immediately at 8-10 liters
per minute to decrease hypoxia.
Choice B is incorrect. Checking the client’s blood pressure is a necessary action, but it should not
be the first action for the nurse to take.
Choice C is incorrect. Morphine sulfate may be given for pain management; however, the nurse’s
initial action would be to provide oxygen.
Nurses’ Notes
1700 – 12-year-old male arrives with his parents after playing outside
with friends and suddenly developing shortness of breath. The client’s
mother believes he is having an asthma attack. He has a medical history
of asthma, insulin dependent diabetes mellitus, and is current on all
immunizations. No known allergies.
Vital Signs
Assessment
Client is alert and fully oriented. Anxious and unable to respond in full sentences.
Appears in significant distress. Peripheral pulses were palpable. Skin was cool and
dry to touch. Respirations were labored with audible wheezes and expiratory
stridor. Tachypnea and use of accessory muscles. Frequent, non-productive cough.
Active bowel sounds in all quadrants. Client reported no pain.
The nurse reviews the assessment information and
identifies that which two (2) pieces of assessment
data require follow-up?
The nurse reviews the assessment information and identifies which two
(2) pieces of assessment data requires follow-up?
a. The client being anxious
b. Non-productive cough
c. Audible expiratory stridor
d. History of diabetes mellitus
e. Temperature of 99 o F (37.2o C)
f. Oxygen saturation of 89%
A cough and the client being anxious are common findings associated with asthma. The
most concerning finding that requires follow-up is the audible stridor and the oxygen
saturation of 89%. Stridor signifies that the upper airways are closing, which indicates that
the asthma attack is advancing. The low oxygen saturation further supports the
seriousness of this asthma attack.
The nurse understands which pathological process best
explains the client assessment findings?
The nurse understands which pathological process best explains the client findings?
Airway hyperresponsiveness and inflammation explain asthma's disease process as both result
in bronchoconstriction, thereby decreasing gas exchange. A client with asthma would have a
decrease in forced expiratory volume, ventilation perfusion mismatch, and an increase in lactic
acid as asthma decreases oxygen causing anaerobic processes leading to the accumulation of
lactic acid.
Complete the sentences from the list of options.
Select
The client is most likely experiencing
pneumonia.
bronchospasm.
pleurisy.
Select
The client is most likely experiencing
pneumonia.
bronchospasm.
pleurisy.
Blood cultures
Intravenous corticosteroids
The nurse notifies the physician of the client’s condition and
prepares to act.
When collaborating with the physician, the nurse should
anticipate or not anticipate which physician order?
Physician Order Anticipated Not Anticipated
Blood cultures X
Intravenous corticosteroids X
Rationale:
Albuterol via nebulizer and intravenous corticosteroids are necessary
to help alleviate this client’s symptoms. This coupled with
supplemental oxygen should provide the client with immediate relief.
Asthma exacerbations are not infectious and the collection of blood
cultures and the administration of antibiotics are not necessary.
Orders
a. Dextromethorphan
b. Magnesium sulfate
c. Vasopressin
d. Diphenhydramine
The nurse received and implemented the physician orders.
Upon reassessment, the client’s respiratory status has not changed.
The nurse anticipates that the physician will prescribe which
medication?
a. Dextromethorphan
b. Magnesium sulfate
c. Vasopressin
d. Diphenhydramine
Magnesium sulfate is third line therapy in the treatment of refractory asthma. Magnesium sulfate
relaxes bronchioles and may further alleviate the client’s symptoms. While diphenhydramine
may be used for allergies that trigger an asthma exacerbation, it would not facilitate
bronchodilation. Dextromethorphan is a cough suppressant not indicated in asthma
exacerbations.
Corticosteroids are activating and may trigger insomnia, if possible, the medications should be taken
earlier in the day. All of the other statements are true, as steroids may cause gastrointestinal upset,
raise blood glucose, and fluctuating mood.
COPD
Nurses’ Note
1530 – 71-year-old male arrives with his daughter reporting increased dyspnea with activity,
productive cough, lethargy, and according to his family, ‘is just not acting right.’ The symptoms
started two days ago, and despite over-the-counter cough medicine, the symptoms are
reported to have worsened. He reports a 4/10 chest pain when he coughs and takes deep
breaths.
Vital signs: temperature 103.7 o F (39.8o C), Pulse 81/minute, Respirations 23/minute, Blood
pressure 139/78 mm Hg, oxygen saturation 89% on room air.
He was recently hospitalized for several days with an acute coronary syndrome that resulted in
angioplasty and the placement of a stent in the coronary artery. The client has a medical
history of hyperlipidemia, osteoarthritis in the knees, and hypertension.
The emergency department (ED) nurse is caring for a client with dyspnea and a
cough.
Assessment
a. Blood pressure
b. Capillary refill
c. Glasgow Coma Scale
d. Oxygen saturation
e. Medical history
f. Respiratory rate
g. Lung sounds
Which (3) three assessment findings require follow-up?
a. Blood pressure
b. Capillary refill
c. Glasgow Coma Scale
d. Oxygen saturation
e. Medical history
f. Respiratory rate
g. Lung sounds
The concerns from the assessment include the client’s oxygen saturation,
respiratory rate, and lung sounds. The client's low oxygen saturation requires
immediate follow-up along with the tachypnea and expiratory wheezes. These
clues indicate that the client is experiencing respiratory distress.
Select:
The nurse understands that if bronchodilator
oxygen and a ______ are not
given, the hypoxia may worsen. epinephrine
diuretic
Rationale
Wheezes make classic high-pitched, squeaky, musical, continuous sound
associated with air rushing through the narrowing of the lower airways.
Wheezes are not commonly cleared with coughing and require treatment
such as a bronchodilator for treatment. Thick, tenacious secretions would
produce a rhonchi type of sound. Inflamed pleura rubbing together
characterizes a pleural friction rub.
Which problem is the client most likely experiencing?
a. Asthma
b. Pneumonia
c. Pleural effusion
d. Septic shock
This client most likely has pneumonia. His biggest risk factor was recent hospitalization which puts
him at risk for health care–associated pneumonia which is more pathogenic. Other symptoms
supporting this likely problem include productive cough, fever, adventitious lung sounds, and
dyspnea.
The client does not have tachycardia which is one of the hallmarks of shock. A pleural effusion is
excluded because it generally does not feature a fever. Asthma is excluded because the client does
not have a medical history of this disorder.
The nurse develops a plan of care for this client and anticipates which orders and
prescriptions from the physician? Select all that apply.
a. Supplemental oxygen
b. Chest radiograph (x-ray)
c. 0.9% saline infusion
d. Hourly blood glucose
e. Laboratory work (CBC, CMP)
f. Blood cultures
g. Acetaminophen
h. Strict bed rest
i. Albuterol via nebulizer
j. Bedside thoracentesis
The nurse develops a plan of care for this client and anticipates which orders and
prescriptions from the physician? Select all that apply.
a. Supplemental oxygen
b. Chest radiograph (x-ray)
c. 0.9% saline infusion
d. Hourly blood glucose
e. Laboratory work (CBC, CMP)
f. Blood cultures
g. Acetaminophen
h. Strict bed rest
i. Albuterol via nebulizer
j. Bedside thoracentesis
Complete the following sentences by choosing from the list of options.
Select
The priority for the nurse is to apply supplemental oxygen.
___________________________ obtain blood cultures.
administer azithromycin.
Select
To optimize this client’s outcome,
physical therapy.
the nurse plans to collaborate with
respiratory therapy.
__________________________
case management.
The nurse re-assesses and updates the nurse’s note after administering the nasal cannula oxygen
and albuterol via nebulizer. Which finding indicates that the client requires further intervention?
a. Reports of nervousness
b. Respiratory rate
c. Pulse rate
d. Oxygen saturation
The nurse re-assesses and updates the nurse’s note after administering the nasal cannula oxygen
and albuterol via nebulizer.
Which finding indicates that the client requires further intervention?
a. Reports of nervousness
b. Respiratory rate
c. Pulse rate
d. Oxygen saturation
Reports of nervousness are a common side effect associated with albuterol. Albuterol causes
stimulation in the sympathetic nervous system and may raise the pulse, making the client feel
nervous/jittery. These are expected effects. The client’s respiratory rate has decreased, but his
oxygen saturation is still a concern because, despite the supplemental oxygen, his saturation is
concerning at 92%