Material Safety Data Sheet
Revision No. : 02
SECTION 1: Identification of the substance/mixture and of the company /
undertaking
a. Product name
b. Recommended use of the
chemical and restrictions
on use
c. Manufacturer information
SECTION 2: Hazards
a. Hazards identification
b. Warning signing item,
including precautionary texts
symbol
Meaning
Hazard texts
Precautionary texts
Precaution
File No. : HB-HA02
Revision date : 2021.06.02
Date of first issue : 2018. 06. 01
Sodium hyaluronate
Raw material for medical device
Name : HYUNDAI BIOLAND Co., Ltd.
Address : 162, Gwahaksaneop 3-ro, Ochang-eup,
Cheongwon-gu, Cheongju-si, Chungcheongbuk-
do, 28125, Republic of Korea
Tel : +82 43-240-8633, 8636
Fax : +82 43-240-8697
Email : jcyoo@hyundaibioland.co.kr
Acute toxicity(oral) : Classification 4
Caution
H302 Harmful if swallowed
P264 Wash thoroughly after handling
P270 Do not eat, drink or smoke when using this product
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Handling the risks
Disuse
SECTION 3: Composition / information on ingredients
a. Name
b. Chemical name
c. CAS No.
d. Concentration
SECTION 4: First aid measures
a. In case of eye contact
b. In case of skin contact
c. If inhaled
d. Ingestion
e. Other medical attention
SECTION 5: Firefighting measures
a. Suitable extinguishing
media
b. Specific hazards arising
from the chemical
c. Special protective actions
for fire-fighters
P301+P312 if swallowed and feel uncomfortable, get medical
attention
P330 Rinse your mouth
P501 (In accordance with applicable regulations) Dispose the
container
Sodium Hyaluronate
Hyaluronic acid. Sodium salt
9067-32-7
100%
Get medical attention
In case of contact, immediately flush eyes and skin with plenty
of water for at least 20 minutes
Get medical attention
Wash with a soap
If skin irritation occurs, seek immediate medical attention
If skin erythema occurs, seek immediate medical attention
Move to fresh air.
If substance is ingested or inhaled, do not use artificial
respiration with mouth-to-mouth method and use appropriate
respiratory medical equipment.
Keep warm and stable.
If substance is ingested or inhaled, do not use artificial
respiration with mouth-to-mouth method and use appropriate
respiratory medical equipment.
Rinse the mouth
Ensure that the medical personnel shall be aware of the
substance and take protective actions.
Use alcohol foam. Carbon dioxide or water spray for
extinguishing related to this substance.
Use dry sand or soil for extinguishing by smothering.
Container may slightly explode on heating.
May burn slightly, but not easily ignite.
Non-inflammable. The substance itself is not burned but can
produce corrosive/toxic fumes when decomposed on heating.
May cause irritative, corrosive and toxic gases in the event of
fire.
Extinguish with maintaining safety distance.
Be aware that it may be transported in molten state.
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SECTION 6: Accidental release measures
a. Personal precautions,
protective equipment and
emergency procedures
b. Environmental precautions
c. The clean-up and removing
way
SECTION 7: Handling and storage
a. Handling
b. Storage
c. Storage conditions
e. Transport
SECTION 8: Exposure controls/personal protection
a. Control parameters
b. Appropriate engineering
controls
Dig a ditch for the disposal of fire-fighting water, and keep it
from dispersing.
Move container from fire-area if it is not hazardous.
Wipe off any spills immediately and, follow ‘personnel
protective equipment’ Item.
Remove all ignition sources.
Stop the leak if it is not hazardous
Do not touch a damaged container and spill without wearing a
personnel protective equipment.
Cover with plastic sheet to prevent fire spreading.
Be aware of conditions and substances to avoid.
Prevent flowing into waterways, sewers, basements and
closed space.
Remove airborne dust and moisten with water for preventing
dust scattering.
Rinse the contaminated area with after control.
Follow precautions of all MSDS/label as product residues may
remain after emptying containers.
Be aware of the substances and conditions to avoid.
Refer to engineering controls and personnel protective
equipment.
Wash thoroughly after handling.
Do not ingest, breathe dust, and smoke dust.
Expiry date : indicated on each package
Do not use after expiry date
Storage at use only between 2~8℃
Keep container tightly closed.
Keep away from sunlight.
Recommended storage conditions should also be followed
during transport.
No data
Equipment for storing or using this material shall be installed
with eye-wash station and safety shower.
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 Wear respiratory protective equipment conforming to the
physicochemical properties of the particulate matter approved
by the Korea occupational safety & health agency.
c. Personal protective The following respiratory protective equipment is
equipment recommended in case of particulate matter.
- Facial filtered dust mask or air filtered dust mask(High-
Respiratory protection efficiency particulate filter media), or dusk mask with
electric fan (Dust and mist filteration)
If Oxygen is poor (<19.6%), wear a ventilation mask or self-
respiratory protective equipment.
Wear breathable safety goggles to protect eyes against
particulate matter that may cause eye irritation or other health
Eye protection hazards.
Install an emergency cleaning facility(shower) and an eye-
wash station where workers can access easy.
Hand protection Wear appropriate protective gloves in consideration of the
physical and chemical properties of the chemical.
Hygiene measures Wear appropriate protective clothing in consideration of the
physical and chemical properties of the chemical.

SECTION 9: Physical and chemical properties

a. Appearance Solid (powder) / White
b. Odour No data
c. Odour Threshold No data
d. pH No data
e. Melting point No data
f. Initial boiling point No data
g. Flash point No data
h. Evaporation rate No data
i. Flammability No data
j. Lower explosion limit and
No data
Upper explosion limit
k. Vapour pressure No data
l. Water solubility No data
m. Relative vapour density No data
n. Specific gravity No data
o. n-octanol-water partition
No data
coefficient
p. Self-ignition temperature No data
q. Decomposition
No data
temperature
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 r. Viscosity No data
s. Molecular weight No data

SECTION 10: Stability and reactivity

a. Chemical stability and
possibility of adverse
reaction
b. Conditions to avoid
c. Substances to avoid
e. Hazardous decomposition
products
Container may slightly explode on heating.
May burn slightly, but not easily ignite.
Non-inflammable. The substance itself is not burned but can
produce corrosive/toxic fumes when decomposed on heating.
May cause irritative, corrosive and toxic gases in the event of
fire.
Ignition source (Heat, spark, flame and etc.)
Combustibles, reducing materials
Corrosive / Toxic hume
Irritating, corrosive and toxic gas.

SECTION 11: Toxicological information

a. Information about highly
probable exposure
No data
pathways
toxicological effects
b. Health hazard information
Acute toxicity
Oral LD50 > 800 mg/kg Rat
Skin No data
Inhalation No data
Skin corrosion / irritation No data
Serious eye damage / eye
No data
irritation
Respiratory No data
hypersensitiveness
skin hypersensitiveness No data
Carcinogenicity
Occupation safety and No data
health acts
Notification of the ministry
of employment and labor No data
IARC
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 OSHA No data
ACGH No data
NTP No data
EU CLP No data
Germ cell mutagenicity No data
Reproduction-toxicity test No data
Specific target organ toxicity
(1 exposure)
Specific target organ toxicity
No data
(Repeated exposure)
Aspiration hazard No data
Other hazardous effects No data

SECTION 12: Ecological information

a. Ecotoxicity effects No data
b. Residue and resolvability No data
c. Bioconcentration No data
d. Mobility in soil No data
e. Other adverse effects No data

SECTION 13: Disposal considerations

a. Disposal methods Pre-process with oil and water separation method
b. Disposal precautions (In accordance with applicable regulations) dispose the
container

SECTION 14: Transport information

a. UN number No classification information of UN transport hazardous
materials
b. IATA Not classified as dangerous by IATA
c. IMDG Not classified as dangerous by IMDG

SECTION 15: Regulatory information

a. Regulation by occupation
N/A
safety and health Act
b. Regulation by chemicals N/A

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 control Act
c. Regulation by safety
control of dangerous N/A
substances Act
d. Regulation by wastes
Specified / designated waste
control Act
e. Regulation by other
domestic and foreign Act
Domestic regulations N/A
Persistent organic
pollutants control Act
Foreign regulations
US administration N/A
information(OSHA)
US administration
N/A
information(CERCLA)

SECTION 16: Other information

Data source

The chemical database, the department of chemistry at the University of

Akron(http://ull.chemistry.uakron.edu/erd) (physical state)
The chemical database, the department of chemistry at the University of
Akron(http://ull.chemistry.uakron.edu/erd) (Color)
National library of medicine(http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?CHEM) (oral)

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