1.

Hypersensitivity Reactions:
Individuals with a known hypersensitivity to
dexamethasone or any other components of Dexatrol
• Edetate Disodium Dihydrate: should avoid using this medication. Allergic reactions can
This ingredient is commonly used as a chelating range from local effects like redness and itching to more
agent to help stabilize the formulation and prevent severe generalized reactions such as skin rash,
degradation of the active ingredients. anaphylaxis, or bullous reactions.
• Hydroxypropyl methylCellulose: 2. Ocular Infections:
help improve the viscosity and retention time of the
Dexatrol should not be used in cases of certain ocular
formulation on the ocular surface. In the context of
infections, including herpes simplex keratitis, viral
dexatrol preparation, HPMC could potentially serve as a
viscosity-enhancing agent to optimize the formulation’s
infections like vaccinia and varicella of the cornea or
performance and efficacy. conjunctiva, fungal diseases of ocular structures,
• Sodium Chloride: untreated parasitic eye infections, and mycobacterial
is used to adjust the tonicity of the solution, making it ocular infections.
compatible with the natural fluids in the eye or ear. 3. Consultation and Monitoring:
• Sodium Hydroxide Patients using Dexatrol containing neomycin sulphate
various purposes such as adjusting pH, solubilizing
should seek medical advice if they experience
components, or facilitating specific chemical
worsening or persistent ocular pain, redness, swelling,
reactions. or irritation. Routine monitoring for adverse reactions
• Benzalkonium chloride and hypersensitivity symptoms is essential during
The presence of BAK in Dexatrol eye drops would serve treatment with Dexatrol.
the purpose of inhibiting microbial growth and extending
the shelf life of the medication.
• Water for Injection:
Dexatrol Water serves as a solvent in the formulation, providing a
medium for all other ingredients to dissolve or disperse
Administration : Hold the dropper
evenly.
directly over the eye and place 1 drop
into the pouch.
5ml Dexatrol 5ml is a medication that
contains dexamethasone, which is a Place the prescribed number of drops
• Ahmed Abdel-Gawad • Ahmed Karam Al-Issawi Aporia corticosteroid used to treat certain eye into the ear canal.
Abdel-Al-Badawi 67 Salem 71 conditions due to inflammation or Dosage for Adults and Children :
• Ahmed Ali Ali Hassan • Ahmed Mohamed Ahmed Taha Children and Adults (including the Elderly):
injury. It works by relieving symptoms
Abdul Rahman Al-Rayes 68 Al-Makawi 72 Eye: Apply 1-2 drops to each affected eye up
• Ahmed Awad Ahmed such as swelling, redness, and itching in
• Ahmed Muhammad Badr Al- to 6 times daily or, more frequently if
Abdel Rahman El Shorbagy Maati Muhammad 73 the eyes. Additionally, it can also be
69 • Ahmed Mohammed Ragheb used to treat swelling, redness, and required.
• Ahmed Fawzy Ahmed Yassin 74 itching of the outer ear due to
Hassan Ismail 70 • Ahmed Muhammad Abdel Khaleq Dexatrol 5ml eye/ear is indicated for the treatment of
inflammatory conditions. steroid-responsive inflammatory conditions in the eye and
Muhammad Ali 75
ear. Specifically, it can be used for conditions such as
allergic conjunctivitis, acne rosacea, superficial punctate
keratitis, herpes zoster keratitis, iritis, cyclitis, selected
infective conjunctivitis, corneal injury from chemical or
Prof. Dr. Irhan Ibrahim Abu Hashim Dexamethasone thermal burns, and penetration of foreign bodies in the
eye.
In the ear, it can be used for inflammatory conditions of
Dr. Walaa Ebrahim Abd El Hady the external auditory meatus like allergic otitis externa and
selected purulent and nonpurulent infective otitis externa.
 Active
Dexameth Neomycin
No interaction studies have been ingredient asone 1mg 3.5mg  Rx
performedConcomitant and/or
Dexamethasone 1 mg (0.1%)
sequential use ofan aminoglycoside
(neomycin) and other Structure Neomycin Sulfate 3.5 mg Neomycin
systemic,oral,topical drugss that
have neurotoxic, ototoxic, Dexamethasone Neomycin
Polymyxin B 10,000 polymyxin B units
anephrotoxic effects may result anti-
applying the
Sulfate
inflammatory
inadditive toxicity and should be and
medication
Benzalkonium
directly to the 0.004%
avoided. If more than one immunosupp Chloride
affected eye(s)
ophthaimic medicinal product is Use ressant
as directed by
properties.
being used, the medicines must be a healthcare
provider.
administered at least 5 minutes 1.place 60%ofwater forinjection(6ml)into a
beaker
apart 2.1.Dissolve the required amounts of
Water
Water Hydroxy propylmethylcelluloseand
solubility:
Solubility solubility: benzalkonium chloride until clear solution
• Hypersensitivity to the active sparingly
freely soluble in the vehiclerespectively.
substances or to any component of the soluble in
preparation Epithelial Herpes Simplex
in water . 2.2.Dilutedhydrochloricacidisaddedin a
water.
keratitis. quantity sufficient toachievethedesired pH
•Vaccinia, varicella, or other viral range foroptimalstabilityandefficacy. 3.
infection of cornea and conjunctiva Add therequiredamountofAntazoline HCl
(except Herpes Zoster Keratitis 1. Temperature: Store the medication at room temperature between 68-77
degrees Fahrenheit (20-25 degrees Celsius). and TetryzolineHCl andstiruntil
• Fungal diseases dos of ocular
2. Protection from Light: Keep the bottle tightly closed and protect it from homogenous distribution
structures. light. Avoid exposing the medication to direct sunlight or bright artificial
• Mycobacterial ocular infections light. 4. Transferthepreparationtoa10ml
3. Avoid Contamination: Ensure that the dropper tip does not touch any measuring cylinder.
surface to prevent contamination. Close the bottle cap tightly after each
use. 5. Wash thebeaker with1-2mlofvehicle and
• Immune system disorders
4. Proper Orientation: Store the bottle upright to prevent leakage and
pourthewash intothemeasuring cylinder.
• Nervous system disorders ensure proper dispensing of the eye drops. 6. Make upthevolumeto10ml.
• Eye disorders: Uncommon: keratitis, 5. Keep Away from Children and Pets: Store Dexatrol eye drops in a safe 7. Transferthepreparationtoaneyedrop
place out of reach of children and pets.
increased intraocular pressure, eye container.secureit andlabelit.
irritation, eye pruritus, ocular discomfort 6. Do Not Freeze: Do not freeze the medication as it may alter its
effectiveness.
• Not known: corneal thinning, photophobia,  . Ceck Expiry Date: Always check the expiration date on the packaging
7
blurred vision, mydriasis, eye pain.  and do not use the eye drops if they are expired.