Drug Class Name Use Mechanism of Adverse Effects Contraindications

Action Monitoring

Tx of Levothyroxine Hypo- Synthetic Overdose of If dosage correct

Thyroid (Synthroid, thyroidism form of T4 hormone= no adverse
disorders Levothroid) thyroxine tachycardia, effects
hormone to nervousness, Lifelong therapy
replace tremors, Check thyroid
hormone insomnia, hormones,
diarrhea, monitor HR, BP
weight loss, Inc
appetite
Propylthiouracil Hyper- Blocks Leukopenia- Check thyroid
(PTU) thyroidism synthesis of low WBCs, hormones
thyroid hypo-
hormone thyroidism,
drowsiness

Tx of Human Regular type 1, type 2, Replaces Hypoglycemia, Administration,

diabetes Insulin-(Humulin R) gestational endogenous insulin shock, mixing, and
Types: diabetes insulin in the hypersensitivit storage
Rapid body to help y reactions considerations-
Short cells utilize Review these!
Intermediate blood glucose
Long
Combo

Oral antidiabetics: Type 2 Stimulate Hypoglycemia Alcohol use can

diabetes release of cause flushing,
Sulfonylureas- insulin from hypo/hyper-
Glyburide (DiaBeta) pancreas in glycemia
response to CI in Sulfa
food allergies or
Improves patients on
insulin binding thiazide diuretics
to receptors Check BS
Biguanides- Type 2 Decreases N/V, abd Can be used in
Metformin diabetes absorption of discomfort, children 10+
(Glucophage) glucose in GI metallic taste, CI in renal
tract, reduces diarrhea, impairment
gluconeogene Lactic acidosis 48 hr wait time
sis (increased before & after IV
lactic acid contrast dye
production) Check BS
Rarely cause
hypoglycemia
Meglitinides- Type 2 Stimulates the Hypoglycemia Can be used in
Repaglinide diabetes release of patients with
(Prandin) insulin from renal impairment
the pancreas Check BS
in response to
food (similar
to
sulfonlyureas)
TZDs-Rosiglitazone Type 2 Increased Fluid retention, Can worsen heart
(Avandia) diabetes cellular edema. failure or pulm
sensitivity to Macular edema
insulin edema, weight Check BS