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CORRECTION IN UHS MCQS SKILLS FOR PHARMACOLOGY BY MEDICOS STUDYING SKILLS (VERSION 2) DATE:31-01-2023

UHS MCQS SKILLS FOR PHARMACOLOGY


CORRECTIONS

SR NO TOPIC PAGE TYPE OF CORRECTED ANSWER


NO MISTAKE
1 CVS 45 Furosemide(B) is Which of the following drug is least useful in the
wrong answer treatment of acute pulmonary edema in a patient of
40 year with an acute left myocardial Infarction:
Mannitol (A ) is a) Mannitol
correct answer b) Furosemide
c) Morphine.
d) Torsemide
e) Ethacrynic acid

Explanation: There are multiple contraindications to giving


mannitol, including: Pulmonary edema or severe
pulmonary congestion, Established anuria due
to renal disease.
Option B,D,E are the Loop diuretics which are used in
treatment of pulmonary edema especially
along with Congestive heart failure
Option C: Morphine has for a long time, been used in
patients with acute pulmonary oedema due to
its anticipated anxiolytic and vasodilatory
properties

2 Chemotherapy 101 Gonorrhea(A) is Q.Indicate the disease in which penicillin G continues to


wrong answer be used as first line treatment in all (unless
contraindicated), because the causative organism
Syphillus(B) is has not developed resistance so
Correct answer a) Gonorrhoea
b) Syphilis
c) Staphylococcal abscess meningitis
d) Haemophilus influenzae
e) Amebiasis
Correct Answer B

The recommended treatment for syphilis is the


antibiotic penicillin, specifically the type known as
penicillin G benzathine (Bicillin L-A). Penicillin has
proven to be effective at killing Treponema pallidum, the
bacterium that causes syphilis
The preferred treatment at all stages is penicillin,But,If
you're allergic to penicillin, your doctor may suggest

1
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CORRECTION IN UHS MCQS SKILLS FOR PHARMACOLOGY BY MEDICOS STUDYING SKILLS (VERSION 2) DATE:31-01-2023

UHS MCQS SKILLS FOR PHARMACOLOGY


CORRECTIONS

another antibiotic(Doxycycline or tetracycline) or


recommend penicillin desensitization

3 ANS 23 B and D both are Which of the following cholinomimetics is indirect-


correct acting?
according to a) Lobeline
statement b) Edrophonium
c) piloca
d) isoflurophate
e) Atropine
Explanation: Edrophonium is reversible indirect acting
cholinomimetic where as isoflurophate is irreversible indirect
acting cholinomimetic.As both are indirect cholinomimetic
that’s why B and D both are correct
4 Endocrine 147 Option C was Which molecule confers glucocorticoid activity on the
wrong corticoid molecule
a) The hydroxyl group at carbon 17.
Option B is b) The hydroxyl group at carbon 11
correct c) The keto group at carbon 3.
d) The keto group at carbon 11.
e) The hydroxyl group at carbon 20.
Correct Answer B
• 11 beta hydroxy is required for glucocorticoid activity
• UHS SKILL POINT: 21-OH require for
minrelocorticoid activity
• 3 keto essential for activity of both Gluco and
mineralocorticoid

5 chemotherapy 79 Option E is A 25 year old lady suffered from opportunistic fungal


wrong according infection due to chemotherapy for which She has
to this scinerio been planned to infuse Amphotrricin B but during its
use she Should be checked for
a) Bone marrow depression
b) Hepatitis
c) Renal tubular necrosis
d) Hypertension
e) Infusion-related adverse effects
Correct Answer C
Amphotericin B cause infusion related adverse effects
which include Fever, Renal Tubular Acidosis (RTA) is an
uncommon but major complication that can occur, and
close monitoring should be performed for rapid
identification and management.
Liposomal formulation of amphotericin will minimize the risk
of renal damage
2
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CORRECTION IN UHS MCQS SKILLS FOR PHARMACOLOGY BY MEDICOS STUDYING SKILLS (VERSION 2) DATE:31-01-2023

UHS MCQS SKILLS FOR PHARMACOLOGY


CORRECTIONS

6 41 Wrong A 35 year old patient suffering from Chronic Gout


answer(A) needs increased urinary excretion of uric acid; one
of the followings will be effective even if he is having
Correct renal insufficiency:
answer(E) a) Probenecid
b) Sulfinpyrazole.
c) Allopurinol.
d) Colchicine.
e) Benzbromarone
Correct Answer E
Benzbromarone and febuxostat could reduce serum uric
acid and maintain renal function in chronic kidney
disease (CKD) patients

7 CVS 38 Wrong answer C Streptokinase


a) Causes hypersensitivity reactions.
Correct answer b) Is an enzyme produced by streptococci
A c) Directly converts plasminogen into plasma
d) Activation plasminogen only inside the thrombus
e) Is recommended for treatment of ischemia stroke
Correct Answer A
Streptokinase can cause hypersensitivity reactions in
some patients, including fever, skin rashes, and
anaphyla
Unlike other plasminogen activators, streptokinase
is not an enzyme and does not directly convert
plasminogen to plasmin• (So option C is incorrect)
t-PA derivatives are used to manage ischemic stroke.
Not streptokinase.

8 Endo 145 Repetition of A 15 year old boy with Type-1 Diabetes Mellitus was
mcq hospitalised due to severe ketoacidosis which
needs rapid control with some appropriate
Wrong antidiabetic drug like:
answer(B) a) crystalline regular insulin
b) insulin lispro
Correct c) NPH insulin
answer(A) d) ultralente insulin
e) Insulin glargine
Correct Answer A
The mainstay in the treatment of DKA involves the
continuous intravenous (IV) infusion of regular
insulin or the frequent subcutaneous (SC) injections
of regular or rapid-acting insulin analogs
3
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CORRECTION IN UHS MCQS SKILLS FOR PHARMACOLOGY BY MEDICOS STUDYING SKILLS (VERSION 2) DATE:31-01-2023

UHS MCQS SKILLS FOR PHARMACOLOGY


CORRECTIONS

9 ANS 25 Typing mistake The site of action of miotics for therapeutic effect in
in options angle closure glaucoma is:
A. Canal of Schlemm
Wrong B. Ciliary body
Answer(A) C. Ciliary muscle
D. Sphincter pupillae muscle
Correct
Correct Answer d
answer(D)
The site of action of miotics for therapeutic effect in angle
closure glaucoma is the sphincter pupillae muscle. Miotics,
also known as cholinomimetic agents, stimulate the
contraction of the sphincter pupillae muscle, which results
in the constriction of the pupil. This leads to increased
outflow of aqueous humor from the eye, which helps to
reduce intraocular pressure (IOP) in patients with angle
closure glaucoma

10 ANS Option B is cut . After systemic administration which of the following


in would not act in the CNS:
printing(Printing a) Clonidine.
error) b) a-methyl norepinephrine
c) Ephedrine
d) Reserpine
Correct answer e) Guanabenz
Correct Answer B
is (B)
Reason:
Catecholamines have poor CNS penetrating ability
Here you can
A methyl norepinephrine binds to and activates peripheral alpha
see option B
2- adrenergic receptors, thereby causing vasoconstriction. Used
as a nasal decongesatn Clonidine ephiderine reserpine and
guanabez have effects on cns

4
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