Pharma Poters

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INTRODUCTION RESULTS

Reactive oxygen species, or ROS, are unstable


molecules produced by our bodies as a byproduct of
normal cellular processes. However, an imbalance
between ROS production and the body's ability to
neutralize them can lead to a condition called
oxidative stress. Oxidative stress is associated with
the development of various chronic diseases.
Antioxidants are natural or man-made compounds
that can help neutralize ROS and protect cells from
oxidative damage. Plants are a rich source of natural
antioxidants, and this study aimed to evaluate the
potential antioxidant activity of extracts from CONCLUSION
Proclaimis nitida and Sida acuta.
Picralima nitida and Sida acuta extracts both
OBJECTIVES possesses flavonoids and phenolic components
though in very low concentrations. Further
Concise Objectives for Antioxidant Activity
investigation is however warranted to optimize
Screening:
extraction methods, identify specific antioxidants
Evaluate the in vitro antioxidant activity of
compounds and explore potential synergistic effects
Proclaimis nitida and Sida acuta extracts. This
among phytochemicals. These findings suggest the
objective broadly outlines the study's purpose.
need for additional research to enhance the
Quantify the free radical scavenging capacity of
antioxidant potential therapeutic applications.
the extracts using DPPH and ABTS assays. This
specifies the methods used to measure REFERENCES
antioxidant activity.
Assess the ferric reducing power of the extracts Gewirtz, D. A. (1986). Doxorubicin (Adriamycin)
using the FRAP assay. This details an additional mechanisms of action. Pharmacology & Therapeutics,
method to evaluate antioxidant potential. 33(4), 227-241.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909
METHODS 145/
Antioxidant Activity Assays
Yildiz, S., & Uygan, C. (2016). The antioxidant effects
DPPH, FRAP, Reducing Power: Measure free
of ellagic acid against doxorubicin-induced
radical scavenging and electron donating ability. cardiotoxicity in rats. Nigerian Journal of Physiological
Chelating Ability: Evaluates iron chelation Sciences, 31(2), 127-133.
potential. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741
Hydroxyl Radical, H2O2, TAC: Assess various 835/
aspects of antioxidant activity.
Total Phenol & Flavonoid Content: Indicate
presence of antioxidant compounds.

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