Review on “Blumea Malcolmii Hook F.

– Medical Plant”

INDEX

Sr. No Title Page no

1. ABSTRACT 2
1.1 INTRODUCTION 3
1.2 HISTORICAL BACKGROUND 4
1.3 LITERATURE OF SURVEY 5

1.4 PLANT PROFILE 6-9

1.5 CHEMICALS CONSTITUENT 10-12
1.6 PHYTOCHEMICAL ANALYSIS 13-14
OF PLANT BLUMEA
MALCOLMII HOOK F.

1.7 USES 15

1.8 CONCLUSION 16

1.9 REFERENCE 17 - 18

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

ABSTRACT -

The Blumea Malcolmii Hook f. is belonging to the family Asteraceae. By qualitative

analysis the main chemical constituent present in Plant is Saponins, glycosides, Volatile oil,
flavonoids glycoside, Alkaloid and Tannins. Blumea Malcolmii Hook f. It is a medicinally
more active plant traditionally used in Chinese medicine. In this review article we will
studied Phytochemical analysis, plant profile like vernacular name of plant, morphological
Classification and taxonomical classification of plan also studied antioxidants, antimicrobial,
anti-inflammatory, cytotoxic, antiproliferative, chemopreventive, antispasmodic, antiulcer,
anticonvulsant, antinociceptive, antiparasitic, larvicidal, Detox, Analgesic and cosmetic
action of plant.

KEY WORDS -

Saponins, glycosides, Volatile oil, flavonoids glycoside, Alkaloid, Tannins, Antibacterial,

Anti-inflammatory, Larvicidal, Antiproliferative, Antinociceptive, Detox.

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

1.1 INTRODUCTION -

Blumea - Genus is tropical Australasian and African herbs or shrubs. simple alternative
leaves and discoid purple or yellow flower heads. 1 Genus Blumea is found in the tropical and
subtropical zones of Asia, especially the Indian Subcontinent and Southeast Asia. A few
species are found in Australia and fewer in Africa .Many species of genus Blumea are used in
traditional Chinese medicine. Other uses include as decorative dry plants.2,3
Blumea malcolmii Hook.F. is an accepted name. The record derives from TICA which
reports it as an accepted name of this species. 4 Malcolm's Blumea is a short herb with strongly
aromatic tap roots, branched stems, woolly with silky white hairs. Synonym of this plant is
Blumea lanuginosa Law ex Cooke Pluchea malcolmii C.B.Clarke. Most of chinese medicines
treat different types of diseases.5
Blumea malcolmi Hook. F. is the name of a plant characterised by different herbal
sources.In current medication, Ayurveda, and other nearby practices or society medication. It
has the accompanying equivalent words: Pluchea malcolmii C.B. Clarke. Recently, Blumea
malcolmii use for Malachite Green dye Erythrina crista-galli for petroleum and Chlorella
were used for photodegradation processes. 6 Blumea MalcolmiiHook F. commonly called as
”panjurt” qualitative analysis by microscopic and phytochemical analysis. In Leave extract of
plant saponins , glycoside, volatile oil, alkaloids, flavonoids, tannins present hence plants is
mostly useful for wound healing property. 7

Fig - 01. Blumea Malcolmii Hook F.

1.2 HISTORICAL BACKGROUND -

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

● EXTRACTION OF ESSENTIALS OIL FROM BLUMEA MALCOLMII

HOOK F. -

1.2.1: REINVESTIGATION OF CARVOTANACETONE -

● The herb has a pleasant camphoraceous smell it was suggested by divisional forest
officer of bngalum, Mr. Hodgson, that might on distillation yield oil.Preliminary
experiment performed by Mr. Puran singh. 16

● The plant was recollected, a distilled oil chemical examination completed in 1921. It
was found that the oil contains two main ketone d-carvatanacetone and L-
tetrahydrocarvone.17

● The unstable mixtures d-carvotanacetone and I-tetrahydrocarvone were recognized

from B. malcolmii utilising stoichiometric investigation, which needs huge amounts of
testing. These days in the field of natural science, different modern programming
based hardware has been created to recognize proof of constituents utilising
exceptionally less amount of test. Subsequently, the point of this study was to
investigate other minor constituents of B. malcolmii and to produce a terpenoid profile
of the natural oil of B. malcolm filling around here. As far as we could possibly know,
this report disperses for the first time following 100 years the total rejuvenating oil
profile of B. malcolm filling in Belgaum and nearby regions.18

Fig - 02 Extractions Of Essential Oil From Blumea Malcolmii Hook F. - BY Steam

distillation

1.3 LITERATURE OF SURVEY

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

Sr. No AUTHOR NAME RESEARCH WORK

● 1. Adiki V . S , shedbalkar Studied on Detoxification of a

UU, Jagtap UB, Bapat carcinogenic paint preservative by
VA. 2011. Blumea malcolmii cell cultures. J
Hazard Mater. 191:150-157.

● 2. Anuradha N. Kagalkar Studied on biotechnological

(1may2009) strategies for phytoremediation of
the sulfonated azo dye Direct Red
5B using Blumea malcolmii,
100:4104-4110.

● 3. Kulkarni M .M, Rojatkar Studied on 4, 6-hydroxyflavanone

SR, Nagasampagi BA. from Blumea malcolmii,
(1987) Phytochemistry. 26:2079-2083.

● 4. Simonsen JL, Rau MG. Studied on The essential oil

(1922) from Blumea malcolmii J Chem
Soc Trans. 121:876-883.

● 5. Dr. R. K. Joshi, Sandeep Reinvestigation of carvotanacetone

Ramchandra Pai (2016) after 100 years along with minor
terpenoid constituents of Blumea
malcolmii Hook F. essential oil

Table no - 01. Literature of survey

1.4 PLANT PROFILE

1.4.1 VERNACULAR NAME - 8

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

In marathi Bhamburda

In hindi Janglimuli

Kanada Gaandhaari gida

Malayalam kukkuravrksam

Sanskrit Kukuradru

Tamil Kattu mullangi, narakkarandai

Telugu Adavi mullangi

Gujarati pilo kapurio

Table no - 02. Vernacular Name

1.4.2 MORPHOLOGICAL CLASSIFICATION -

1. Stem –
Branched base stem, woolly stem with silky white hairs. Length of plant is 1-2 ft.
Stem covered with rough wool used for wound healing activity.

Fig -03 Stem

2. Roots –
Strongly aromatic and tap roots present in the Blumea Malcolmii plant.
Roots are aromatic. They are used as blood purifier.

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

Fig - 04 Roots

3. Leaves -

★ Inverted-lance shaped

★ 1-2 cm into 0.7 - 5 cm

★ Stalkless leaves

★ Spiny - sawtoothed

★ Basal leaves larger than upper leaves

★ Carvacetone essential oils present large amount in leaves.

★ Alternative leaves are present

★ Antimicrobial and Antibacterial activity mainly shows.

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

Fig No -05 Leaves

4. Flower -

★ Clustered at the end of the branch.

★ 7-11 mm across

★ Stalks of flower cluster 2 cm long

★ Involucral bracts linear

★ Dorsal surface

★ Bisexual

★ Yellow velvet hairs

★ Marginal florets is female flower

★ Flowering Time is - November - December 9

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

Fig no - 06 flower

1.4. 3 TAXONOMICAL CLASSIFICATION - 3

Kingdom Plantae

Clade Tracheophytes

Class Magnoliopsida

Order Asterales

Family Asteraceae

Genus Blumea

Species Blumea malcolmii Hook.f

Common name Pluchea blumea

Table no - 03 Taxonomical classification

1.5 CHEMICALS CONSTITUENT -

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

★ Saponin

★ Glycoside

★ Volatile oil

★ flavonoids

★ glycoside

★ Alkaloid

★ Tannins 10.

Sr. No Chemical constituent Percentage

1. Oxygenated monoterpenes 99.2%

(oil content)

2. Carvotanacetone 92%

3. Beta-caryophyllene 1.1%

4. Monoterpenes hydrocarbons 2.4%

5. Carvomenthone 2.3%

6. Sesquiterpene hydrocarbon 1.1%

7. Phenylpropanoids 0.7%

Table no - 04. Chemical constituent

1. Carvotanacetone -

● Carvotanacetone present large amounts in Leaves of Blumea

Malcolmii Hook f.

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

● In 92% essential oil carvacetone present

Structure. 01. Carvotanacetone

● Carvotanacetone is present in large amounts in plants by synthetic method

carvacetone prepared by using a methylerythritol phosphate pathway using plastids
via a geranyl-pyrophosphate by using limonene intermediate.

● Carvacetone formed a large amount of ketone. 92% carvacetone present in Blumea

Malcolmii Hook f. hence the plant shows Antioxidants, Antibacterial, Anti-
inflammatory, Cytotoxic activity. 11
2. Carvomenthone –

Structure – 02. Carvomenthone

● The meaning of Carvomenthone is a colourless oily terpenoid ketone C10H18O

occurring with carvotanacetone in some essential oils. 12

3. Beta-caryophyllene -

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

Structure-03. Beta caryophyllene

● Beta-caryophyllene is a pale yellow oily liquid with an odor of cloves and turpentine.
Found in many essential oils, Used in perfumes; Used as flavoring agent or adjuvant
and colouring agent for foods, Also used to suppress intestinal bacteria. 13

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

1.6 Phytochemical analysis of plant Blumea Malcolmii Hook F. 14

SR. Test Methanol Ethanol Chlorofor Water

No. extract extract m extract extract

1. Carbohydrtes - - - -
Molisch test

Fehling test - - - +

2. Protien biuret - - - -
test

Millon test - - - -

3. Steroid - + - + -
salkowki test

Liberman + + - -
burchard test

4. Anthrquinone - - - -
glycoside -
borntrager test

5. Saponins - - + -
Glycoside foam
test

6. Flavonoids + - - +
shinoda test

7. Tannins 5% + + + +
fecl3 solution

8. Alkaloids + + - -
dragendroff test

Table no - 05 Phytochemical analysis

1.7 PHYSICO - CHEMICAL PARAMETERS 14

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

1.7.1 ASH VALUE -

Sr. No Parameter Value

1. Total ash value 20%w/w

2. Acid insoluble ash value 2.1% w/w

3. Water soluble ash value 49% w/w

1.7.2 Extractive value -

Sr. No Parameter. Value

1. Extractive value

2. Alcohol soluble extractive value 1% w/w

3. Water soluble extractive value 59% w/w

1.7.3 Moisture content -

● Moisture content of Blumea Malcolmii Hook f. Is 5% w/ w

1.7.4 Foaming index -

● Foaming index of Blumea Malcolmii Hook f. Is 2000 14

1.8 USES -
Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar
 Review on “Blumea Malcolmii Hook F. – Medical Plant”

1. An important medicinal plant used as an important ingredient of Herbal Cigarettes in

Traditional Healing.

2. Antioxidant

3. Antimicrobial

4. Anti-inflammatory

5. Cytotoxic

6. Antiproliferative

7. Chemopreventive

8. Antispasmodic

9. Antiulcer

10. Anticonvulsant

11. Antinociceptive

12. Antiparasitic

13. larvicidal

14. Detox

15. Analgesic

16. Cosmetic.15

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

1.8 CONCLUSION-

Phytochemical investigation of Malcolm's Blumea, its chemical constituent and

medicinal uses is studied by this review as well as studied exploration of species in
pharmaceutical dosage form. The species related information is not available in large amount.
Plant use for Anti-inflammatory, Cytotoxic, Antiproliferative, Chemopreventive,
Antispasmodic, Antiulcer, Anticonvulsant, Antinociceptive, Antiparasitic, larvicidal,
Insecticidal, Cosmetic purpose. Pharmacognostic and Phytochemical study on the Leaves
of Blumea malcolmii Hook.f has shown that they can be used efficiently as therapeutic
agents due to its various phytochemical constituents. Further studies are required to
investigate various biological activities of the Phytoconstituents.

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

1.8 REFERENCE-

1. Rajesh K. Joshi & Sandeep R. Pai Reinvestigation of carvotanacetone after 100 years
along with minor terpenoids constituent of blumea malcolmii hook f. page no.2368 –
2371 ; 19 april 2016.

2. Plants of the world online Royal Botanic Garden , kew. Reteieved 31 dec.2020.

3. S.S.Kolhe , & R.S. Tripathi . “Alleopathic effect of Blumea lacera l.on rice and
common kharif weeds “Oryza 35.2 (1998): 175-177.

4. “Blumea DC” plants of the world online Royal Botanic gardens Kew retrived 31 dec
2020.

5. Wisdomlib Blumea malcolmii item last updated 13 july 2022.

6. Ibrahim Ilker Ozyigit and Ilhan Dogan , plant – microbe interactions in

phytoremediation , page no 259.

7. Hiral surani pharmacognastic and phytochemicals evaluation of blumea species .

international journal of botany studies ,October 2021.

8. Shrikant Ingalhalikar ,flowers of india ,29 dec 2007.

9. Sushant more ,flowers of india ,Malcom’s blumea

10. Vaibhav Rajendra Suryawanshi, Hariram Ramashray Yadav, Hiral Chatur Surani
Pharmacognostic and phytochemical evaluation of Blumea species Phytochemistry
26, 2079-2083.

11. Derivatives Djilal. Biosynthesis and Biological Activities of Carvone and

Carvotanacetone Published: 14 September 2022.

12. “Carvomethone “ Merriam –Webster .com Dictionary , 29 oct 2022.

13. National library of medicine ,pubchem ,caryophyllene 28 april 2006.

14. Vaibhav Rajendra Suryawanshi, Pharmacognostic & Phytochemicals evaluation of

Blumea species.

15. Blumea Malcolmii hook f. ,fl.brit.india 3:266 (1881).

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar

 Review on “Blumea Malcolmii Hook F. – Medical Plant”

16. Simonsen JL, Rau MG. 1922. The essential oil from Blumea malcolmi. J Chem Soc
Trans. 121:876-883.

17. Ross SA, El Sayed KA, El Sohly MA, Hamann MT, Abdel-Halim OB, Ahmed AF,
Ahmed MM. 1997. Phytochemical analysis of Geigeria alata and Francoeuria crispa
essential oils Planta Med. 63:479-482.

18. Adki VS, Shedbalkar UU, Jagtap UB, Jadhav JP, Bapat VA. 2011. Detoxification of a
carcinogenic paint preservative by Blumea malcolmii Hook cell cultures. J Hazard
Mater. 191:150-157.

Dr . Naikwadi College of Pharmacy, Jamgaon ,Sinnar