Biochemistry mcqs

1. In human, prostaglandins can be derived from:

A. Glucose
B. Acetyl CoA
C. Arachidonic acid
D. Oleic acid
E. Leukotrienes

2. Which of the following sequences places the lipoproteins in the order of most dense
to least dense (from left to right)?
A. HDL/ VLDL / chylomicrons / LDL.
B. HDL / LDL/ VLDL / chylomicrons.
C. LDL / chylomicrons / HDL / VLDL.
D. VLDL / chylomjcrons / LDL / HDL.
E. LDL / chylomicrons/ VLDL / HDL.

3. All glycerol phospholipids are synthesized from:

A. Triacylglycerols
B. Cephalin
C. Phosphatidic acid
D. Diacyiglycerols
E.Monoacyiglycerols

4. Which of the following is an essential fatty acid?

A. acetic acid
B. stearic acid
C. palmitic acid
D. linoleic acid
E. nervonic acid

5. Sphingomyelin is composed of
A. Glycerol, 2 fatty acids, phosphpate, choline
B.Glycerol, 2 fatty acids, phosphate, ethanoamine
C. Sphinosine, fatty acid, phosphate,choline
D. Sphinganine, fatty acid, phosphate,choline
E. Sphingosine, fatty acid, glucose

6. The low value of Km indicates

a. High enzyme activity
b. High substrate affinity of enzyme
c. No effect on reaction
d. Low affinity of enzyme with substrate
e. High enzyme specificity
7. Km values are not altered by which type of inhibitor
a. Competitive inhibitors
b. Non competitive inhibitors
c. Uncompetitive inhibitors
d. Irreversible inhibitors
e. All of these

8. An allosteric modulator influences enzyme activity by

a. Competing for the catalytic site with the substrate
b. Binding to a site on the enzyme molecule distinct from the catalytic site
c. Changing the nature of the product formed
d. Covalently modifying enzyme
e. Increasing enzyme specificity

9. If the substrate concentration in an enzyme catalyzed reaction is equal to Km, the

initial reaction velocity will be
a. 0.25 Vmax
b. 0.33 Vmax
c. 0.50 Vmax
d. 0.75 Vmax
e. 1.5 Vmax

10. The typical saturation curve for an enzyme catalyzed reaction is sigmoidal. This
indicates that the enzyme is
a. Allosteric enzyme
b. Isoenzyme
c. Riboenzyme
d. Holoenzyme
e. Apoenzyme

11. Michaelis constant Km is

a. Dependent on enzyme concentration
b. Independent of Ph
c. Equal to substrate concentration that gives half Vmax
d. Numerically equal to half Vmax
e. Numerically equal to twice Vmax

12. Lactate dehydrogenase is a

a. Coenzyme
b. Isoenzyme
c. Zymogen
d. Apozyme
e. Prosthetic group

13. Both Vmax and Km values are altered in

a. Competitive inhibition
b. Noncompetitive inhibition
 c. Uncompetitive inhibition
d. All of these

14. A competitive inhibitor of an enzyme

a. Increases Km without affecting Vmax
b. Decreases Km without affecting Vmax
c. Increases Vmax without affecting Km
d. Decreases Vmax without affecting Km
e. Decreases both Vmax and Km

15. A competitive inhibitor binds to

a. Substrate
b. Active site
c. Allosteric site
d. Coenzyme
e. Enzyme-substrate complex

16. The inactive precursor of an active enzyme is called

a. Zymogen
b. Ribozyme
c. Isozyme
d. Apoenzyme
e. Holoenzyme

17. In chemiosmosis, ATP is produced as hydrogen ions (protons) pass through:

a. the outer mitochondrial membrane.
b. ATP synthase.
c. ATP dehydrogenase.
d. ATP decarboxylase.
e. a series of electron carriers

18. Oxidation is the __________, and reduction is the __________.

a. gain of electrons . . . loss of electrons
b. loss of electrons . . . gain of electrons
c. gain of protons . . . loss of protons
d. gain of oxygen . . . loss of oxygen
e. loss of oxygen . . . gain of oxygen

19. In the electron transport chain, the final electron acceptor is

a. a molecule of water.
b. a molecule of carbon dioxide.
c. ATP.
d. ADP.
e. an oxygen atom.
20. In oxidative phosphorylation, the oxidation of one NAD+H+ to NAD+ produces
how many ATPs?
a. 2
b. 3
c. 4
d. 5
e. 6