TOTAL NUMBER OF PRINTED PAGES – 2.

2023
(April)
PHYSIOLOGY
Phase I – 1st Internal Assessment – Remedial Examination
Full Marks: 100
Time: 3 Hours

The Figures in the margin indicates full marks for the question
Answer All questions

1. What is erythropoiesis? Describe the steps of erythropoiesis. What are

the factors effecting erythropoiesis? Define anaemia.
2+6+5+2=15

2. Write short notes on: 5 × 6 =

30
I. Rh blood group system.
II. Morphology of RBC and its physiological advantage.
III. Surfactant.
IV. Respiratory membrane.
V. Sodium Potassium ATPase pump and its functions.
VI. Neuro-muscular junction.
3. What are the barriers of communication 5
4. Give the physiological basis of: 5 × 4 = 20
I. Cyanosis is not seen in severe anaemia.
II. Alveoli don’t collapse during expiration.
III. Resting membrane potential.
IV. Role of booster dose in vaccination.
5. A 30 years old lady presented with history of cough and breathlessness
that got worse during the winter months every year. She also complained
of occasional whistling sounds arising from the chest during breathing.
Answer the following: 1+3+1+4+1=10

I. What is the most likely clinical diagnosis of her condition?

II. What major findings would her pulmonary function tests show?
III. What kind of medication would she likely benefit from?
IV. Depict the different lung volumes and capacities with the help of a
neatly labelled diagram
V. What is the significance of residual volume?
 (Turn over)
6. Choose the correct answer (write the response in full in your copy) 1×20=20

XI. The most abundant anion in ICF is I. Most of the iron in the body is present in:
a. Bicarbonate a. Hemoglobin
b. Chloride b. Myoglobin
c. Phosphate c. Ferritin
d. Potassium d. Transferrin
XII. InQuestion No the value
the steady state, Answer
of which of the following II. Red cell antigens A and B are chemically:
variables is the same in ICF and ECF? a. Phospholipids
a. IPh d. Potassium b. Glycosphingolipids
b. Osmolality
II
c. Concentration of proteins
b. Osmolality c. Glycopeptides
d. Polypeptides
d. III
Number of Sodium ion d. water III. ESR is increased in:
XIII. Of the following substances, the lipid bilayer is most
IV
permeable to: b. Na-K ATPase pump a. Anemia
a. Sodium ions b. Hypofibrinogenemia
b. VUrea c. Potassium efflux through c. potassium
Spherocytosisleak channels
c. VIGlucose a. connexin d. Polycythemia
d. Water IV. Which of the following is not synthesized in the liver?
XIV. VII
Cell volume and pressure b.is mainly
K dependent upon a. Igg
activity of: b. Α2 macroglobulin
VIII a. albumin c. Albumin
a. Na glucose cotransporter
IX
b. Na-K atpase pump b. Factor V d. Angiotensinogen
c. C. Glucose transporter V. The maximum amount of gas that can be exhaled
X
d. D. Na-Ca exchanger
b. H substance after a full inspiration is called:
XV. XI
Which of the following isa.an example
hemoglobin
of passive a. Expiratory reserve volume
transport? b. Vital capacity
XII b.
a. Calcium efflux by calcium pump glycosphingolipids c. Total lung capacity
b. XIII
Na-Ca exchanger a. anemia d. Functional residual capacity
c. Potassium efflux through potassium leak channels VI. What is the maximum amount of oxygen a gram of Hb
d. XIV
Calcium sequestration ina.sarcoplasmic
IgG reticulum A can bind?
XVI. Gap junctions are made up of a protein called: a. 1 ml
XV b. vital capacity b. 1.34 ml
a. Connexin
b. XVI
Clathrin b. 1.34 ml c. 15 ml
c. Cadherin d. 20 ml
XVII
d. Calcineurin
c. PaO2 VII. The amount of oxygen dissolved in plasma relates most
XVII. XVIII a.
The resting membrane potential Bohr effect
of neurons is equal closely with:
or near equal to the equilibrium potential of: a. Fio2
a. XIX
Na a. CO2 b. Tidal Volume
b. XXK c. hypercapnia. c. Pao2
c. Cl d. Blood [Hb]
d. Ca VIII. The decrease in oxygen affinity of Hb when the ph of
XVIII. The most abundant protein in blood plasma is: blood in tissues falls is:
a. Albumin a. Bohr effect
b. Myoglobin b. Haldane effect
c. Fibrinogen c. Hawthorne effect
d. Beta-1 globulin d. Hamburger effect
XIX. Which of the following clotting factors is not IX. Normally, the major stimulus for spontaneous
Vitamin K dependent? respiration is:
a. Factor II a. CO2
b. Factor V b. O2
c. Factor VII c. Lactate
d. Factor X d. HCO3
XX. The red blood cells of a person with the X. Hyperbaric oxygen therapy is useful in the
Bombay blood group do not have: management of all except:
a. GLUT a. Cyanide poisoning
b. H substance b. Carbon monoxide poisoning
c. Spectrin c. Hypercapnia.
d. Ankyrin d. Decompression sickness