Professional Documents
Culture Documents
Full Ebook of Emerging Technologies in Oral and Maxillofacial Surgery Arash Khojasteh Editor Online PDF All Chapter
Full Ebook of Emerging Technologies in Oral and Maxillofacial Surgery Arash Khojasteh Editor Online PDF All Chapter
https://ebookmeta.com/product/oral-and-maxillofacial-surgery-
revision-study-guide-abdul-ahmed/
https://ebookmeta.com/product/basic-guide-to-oral-and-
maxillofacial-surgery-1st-edition-nicola-rogers/
https://ebookmeta.com/product/peterson-s-principles-of-oral-and-
maxillofacial-surgery-4th-edition-michael-miloro/
https://ebookmeta.com/product/oral-and-maxillofacial-surgery-for-
the-medically-compromised-patient-a-guide-to-management-and-care/
Peterson s principles of oral and maxillofacial surgery
3rd Edition Michael Miloro Larry J Peterson
https://ebookmeta.com/product/peterson-s-principles-of-oral-and-
maxillofacial-surgery-3rd-edition-michael-miloro-larry-j-
peterson/
https://ebookmeta.com/product/clinician-s-handbook-of-oral-and-
maxillofacial-surgery-2nd-edition-daniel-m-laskin-eric-r-carlson/
https://ebookmeta.com/product/oxford-textbook-of-anaesthesia-for-
oral-and-maxillofacial-surgery-second-edition-patrick-a-ward-
editor-and-michael-g-irwin-editor/
https://ebookmeta.com/product/diagnostic-imaging-oral-and-
maxillofacial-2nd-edition-lisa-j-koenig/
https://ebookmeta.com/product/emerging-technologies-in-
agriculture-livestock-and-climate-abid-yahya/
Editors
Arash Khojasteh, Ashraf F. Ayoub and Nasser Nadjmi
Ashraf F. Ayoub
School of Medicine, University of Glasgow, Glasgow, UK
Nasser Nadjmi
Department of Maxillofacial Surgery, University of Antwerp, Antwerp,
Belgium
This work is subject to copyright. All rights are solely and exclusively
licensed by the Publisher, whether the whole or part of the material is
concerned, specifically the rights of translation, reprinting, reuse of
illustrations, recitation, broadcasting, reproduction on microfilms or in
any other physical way, and transmission or information storage and
retrieval, electronic adaptation, computer software, or by similar or
dissimilar methodology now known or hereafter developed.
The publisher, the authors, and the editors are safe to assume that the
advice and information in this book are believed to be true and accurate
at the date of publication. Neither the publisher nor the authors or the
editors give a warranty, expressed or implied, with respect to the
material contained herein or for any errors or omissions that may have
been made. The publisher remains neutral with regard to jurisdictional
claims in published maps and institutional affiliations.
Ashraf F. Ayoub
is an OMFS professor at the University of Glasgow, UK, since 2003. He is
the editor-in-chief of Frontiers of Oral & Maxillofacial Surgery and the
director of the university’s postgraduate program. Prof. Ayoub is the
lead surgeon of a team consisting of orthodontists, technologists,
psychologists, and computer scientists to investigate facial
malformations. He has received several awards and honors and
published numerous articles on two research themes, tissue
bioengineering and facial imaging. He has given several lectures on the
same topic at many national and international conferences.
Nasser Nadjmi
is currently working as a professor and coordinating program director
for OMFS at the University of Antwerp (UA), Belgium. He graduated as
an aspirant officer in merchant marine from Nautical College of
Antwerp-Belgium. Subsequently, he finished his medical and dental
education at the Catholic University of Leuven-Belgium. He was trained
in cranio-maxillofacial surgery in Belgium (Bruges and Leuven) and the
USA (Houston, Detroit, and Miami).
© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023
A. Khojasteh et al. (eds.), Emerging Technologies in Oral and Maxillofacial Surgery
https://doi.org/10.1007/978-981-19-8602-4_1
1 Introduction
The multiple industrial revolutions have well impacted consolidation of
modern technologies with the field of oral and maxillofacial surgeries.
Following the two first industrial revolutions, the third one, namely, the
“digital revolution,” started in 1960 by the end of world wars [1]. Digital
revolution was characterized by implementation of electronics and
information technology for automated production [2]. Digital
revolution occurred after a slowdown of industrialization and
technological advancements and accelerated development of
technological advancements. Consequently, machinery forces alleviated
the need for human labor, resulting in the emergence and stemming of
fourth industrial revolution from the third. The fourth industrial
revolution entails computer-generated product design and three-
dimensional (3D) printing technologies that fabricate solid objects
through piling successive layers of working materials [2, 3]. This era is
characterized by fused technologies that blur borders of physical,
digital, and biological territories.
The essential part of this change has been developed in the
computer-aided design system (CAD) and subsequent computer-aided
manufacturing (CAM). Following the progress of CAD/CAM, robotic
surgeries (navigation surgeries) evolved, leading to the establishment
of trans-oral robotic surgery (TORS). Subsequently, the two presented
themselves to regenerative dentistry. This led to the advent of areas of
bioprinting and bioreactor. The current chapter encompasses a general
introduction of these new technologies and their applications in oral
and maxillofacial surgeries.
CAD technologies have been implemented in dentistry for nearly
two decades [4]. In the field of oral and maxillofacial surgery, CAD can
be used for virtual surgical planning (VSP) [5–8] and designing of
surgical guides and splints [9–11]. CAD technology has also a new area
in dental and medical education, referred to as “virtual-based
learning”(VBL).
Along with CAD, CAM technologies have also progressed
significantly and well-incorporated in different regions of dentistry.
Additive manufacturing (AM) and subtractive manufacturing (SM) are
two chief subbranches of CAM systems.
These technologies have resolved many formidable challenges of
surgical reconstruction and corrections, arising mainly from the
complex three-dimensional anatomy of the craniofacial skeleton [12]
(Fig. 1).
Fig. 1 Flowchart of advanced technology (ATM) in oral and maxillofacial surgery
(OMFS). CAD computer-aided design system, CAM computer-aided manufacturing,
VSP virtual surgical planning, VBL virtual-based learning, AM additive manufacturing,
SM subtractive manufacturing, SLA stereolithography, DLP digital light processing,
FDM fused deposition modeling, SLS selective laser sintering, SLM selective laser
melting, TORS trans-oral robotic surgery
CAD systems, being produced following the third industrial
revolution and the advancement of computer models in medical
science, enable object modeling before design and analysis. To perform
modeling, the object must be photographed with a 3D scanner or 3D
imaging systems. Today, many intraoral and extraoral scanners are
commercially available for 3D modeling, shaping, and imaging. In
addition to 3D modeling, a software is needed to manipulate the 3D
objects. In order for the photographed object to be manipulated by the
software, it must be converted into an STL file format. In this format,
regardless of its color, the object will have points in a three-dimensional
space, providing the system with spatial object topographies.
Thereafter, the STL formatted-file is rendered in the software to shape
and assess it. In the field of oral and maxillofacial surgery, CAD has also
led to emergence of virtual surgical planning (VSP) and designing of
surgical guides, splints, and implants. Virtual-based learning (VBL) is
another CAD-based technology that is the new branch in dental
education.
CAM system, which was created after the third and fourth industrial
revolutions, is the result of combined use of software and computer-
controlled machinery, without any manual intervention, aiming to
provide a fully automated manufacturing process [13, 14]. CAM
includes two subbranches: additive manufacturing (AM) and
subtractive manufacturing (SM) [15]. AM is defined as quantifiable
layer-by-layer deposition of working materials to directly obtain CAD-
based 3D objects [16, 17]. In this light, CAD/CAM benefits fabrication of
geometrically complex assemblies from a flexible selection of materials
[16, 18]. AM, also known as 3D printing, includes techniques such as
binder jetting (inkjet printing), stereolithography (SLA)/digital light
processing (DLP), fused deposition modeling (FDM), and selective laser
sintering (SLS)/selective laser melting (SLM) [15]. On the contrary, the
controlled process of material removal and machining, drilling, and
milling solid blocks is categorized as subtractive manufacturing
technologies (SM).
Following the advancement of CAD/CAM systems, robotic surgeries
were also evolved. Facilitated performing of these surgeries is among
the many goals of integrating CAD/CAM technologies with medical
sciences. Robotic surgery or navigation surgery aims to employ a
minimally invasive approach to access not-easily-accessible anatomical
areas, for instance, posterior of the oral cavity, such as oropharynx,
larynx, and hypopharynx, or even the skull base [19–21]. Combining
VSP with robotic surgeries has been demonstrated to cut down on
operative durations and improve patient outcomes, rather than sole
robotic surgery [20, 22]. In trans-oral robotic surgery (TORS), the robot
is fixated within the oral cavity while surgeon views the surgical field
on the monitor. This method can benefit educational purpose through
providing better visualization of the surgical environment for all
students and residents.
Today, medicine has evolved from replacement therapies toward
regenerative therapies. Therefore, tissue engineering products have
gained attention of many researchers and clinicians. Contemporary
tissue engineering-based approaches often employ a cocktail of stem
cells, growth factors, scaffolds, and bioreactors, aiming to initiate and
support regeneration aptitudes of host body [23]. The aforementioned
technologies can be used to make these products.
The field of regenerative dentistry has made great strides in this
field using advanced technologies. Two of the most important
applications of new technologies that are desired in this field are
bioprinting and bioreactors.
In order to produce engineered tissue, it is necessary to examine
and bio-design the micro- and macro-environments of tissues. This is
done with the purpose of imitation of physiological and mechanical
tissue conditions, outside the body [24, 25]. Bioreactors are used to
somewhat mimic the body’s physiological and mechanical
characteristics [24]. There are different types of systems for the
bioreactor’s design, including (1) hydrodynamic shear stress, (2) direct
mechanical stress, and (3) electromagnetic field (EMF)-based
bioreactors [24–26].
Bioprinting refers to additive manufacturing technologies in which
the scaffold is fabricated from a blend of cells and biocompatible
materials, the so-called bio-ink, in a layer-by-layer manner [27].
Categorization of the commonly used bioprinting technologies were
extrusion-based methods, laser-based methods, and inkjet bioprinting
[28].
All fields of applied modern technologies in the field of oral and
maxillofacial surgery are furtherly discussed in the following chapters.
The applications of CAD/CAM in the field of oral and maxillofacial
surgery are bone reconstruction surgeries, orthognathic surgeries,
implant dentistry, and trans-oral robotic surgery (Fig. 2) [8, 11, 29–34].
Fig. 2 Flowchart of applications of CAD/CAM in oral and maxillofacial surgery
(OMFS). PSI patient-specific implants, VSP patient-specific implants
The reconstruction procedure aims to reestablish the form and the
function of the defectious areas. Donor site morbidity, limited donor
tissue, incompatible features among recipient versus donor tissue,
unpredictable resorption, and varying long-term results are the main
disadvantages of the traditional reconstructive methods [35].
Therefore, CAD/CAM-based methods have gained an increased
attention in terms of overcoming these drawbacks. In bone
reconstruction, CAD/CAM can be used for virtual defect design, i.e.,
virtual surgical planning (VSP) [8, 36]. It can also be used for
prototyping or creating a defect model, which involves thorough defect
modeling and visualization preoperatively [37]. Of note, it can highly
contribute to making patient-specific implants (PSI) [8, 38]. In
orthognathic surgeries, CAD/CAM can be used for VSP [39, 40]. It is also
used in fabrication of surgical guides, mainly facilitating and benefitting
the surgical trajectory time-wise [11]. In the field of dental implants,
CAD/CAM is also used in surgical stents [41]. Navigational surgery is
also one of their applications in implantology [42]. Finally, in robotic
surgeries, trans-oral robotic (cleft palate) surgery (TORCS) is chiefly
implemented in soft tissue surgeries of the posterior portion of
pharynx, such as the soft palate [43].
In OMFS reconstructions, entire condition and three-dimensional
topography of tumor or defect can be evaluated and investigated on the
computer monitor, preoperatively [8, 36]. This allows a relaxed and
laid-back approach to be achieved for thorough assessments. In
prototyping, the defect model or tumor model may be consisted of a
polymeric content, modeling the jaws. This furtherly contributes to
comprehensive evaluations in terms of tumor/defect expansive
specifics, etc., to be performed not only preoperatively but also even
prior to meeting the patient and viewing the two-dimensional
radiographies. In prototyping or model design, mainly curable
polymers with lower temperatures can be employed [44]. For example,
FDM systems are very suitable for fabricating CAD models [44].
Therefore, CAD/CAM in bone reconstruction and bone grafting can
assist fabrication of patient-specific bone implants and preserving the
protected healing space for in situ bone regeneration (Fig. 3).
Fig. 3 Flowchart of applications of CAD/CAM in bone reconstruction surgery.
PMMA polymethyl methacrylate, HDPE high-density polyethylenes, PTFE
polytetrafluoroethylene, PEEK polyether ether ketone, GelMA gelatin and
methacrylate, PEG polyethylene glycol, Ti titanium, Ta tantalum, SS stainless steel,
ECM extracellular matrix, TCP tricalcium phosphate, HA hydroxyapatite, PDLLA poly
(d,l-lactic acid), PCL polycaprolactone, FDM fused deposition modeling, SLS selective
laser sintering, SLM selective laser melting
Bone contouring, functional bone replacement, and functional bone
regeneration (FBR) can be achieved through application of bone
implants [45–47].
Bone contouring refers to the usage of patient-specific products to
restore the standard and anatomical contour of the bone. The
individualized products are implanted in areas with nonspecific
masticatory role and are not prone to undergoing jaw movement or
functional or loadbearing incidents [48]. In bone contouring, there is
mainly a need for prosthesis, meaning that the implanted substance
will remain in place. In this field, polymers such as polymethyl
methacrylate (PMMA) are mainly used [49]. In this case, FDM printer
can be used. High-density polyethylenes (HDPE), such as
polytetrafluoroethylene (PTFE) or polyether ether ketone (PEEK), are
employed for fabrication of bone contouring prostheses, and chin or
cheek prostheses as well [50, 51]. Upon application of these materials,
the selective laser sintering (SLS) method of AM is required [52].
On the other hand, aiming for functional bone replacement,
implants must restore the functional behaviors of the resected tissue,
including both mastication and jaw movement. In functional bone
replacement, the resected region is replaced by a prosthesis that not
only plays a functional role but can also generate and feasibly
withstand the masticatory forces. While for functional bone
replacement, the applied material has to tolerate the external forces
and provide proper contour. Nowadays, the most commonly employed
materials for fabrication of functional bone replacement prosthesis are
titanium in the bones and tantalum in the spine area [53, 54]. In the
past, stainless steels were used with this regard, but due to corrosive
reactions and numerous postoperative complications, leading to screw
loosening and macrophage inflammatory reactions, their application
has minimized considerably [55, 56]. The use of titanium and tantalum
in CAD/CAM is due to their high melting point, making them usable
with AM methods, such as selective laser melting (SLM).
In functional bone regeneration, a three-dimensional scaffold is
fabricated. The implanted scaffolds tend to induce bone formation, in
order to replace the lost tissue and restore both function and form of
the defected area using host body’s regenerative abilities. Tissue
engineering scaffolds have been used to provide spatial support to
enable new bone formation in defected sites. In the other words,
scaffolds should optimally imitate the native properties of extracellular
matrix (ECM), both the mineral and organic portions of the native bone
tissue ECM [26]. Upon placement, the scaffold will undergo degradation
and be replaced over a period of 6–18 months with natural bone tissue
of normal anatomical features [57]. In functional bone regeneration,
materials that take the shape similar to bone at a lower temperature
are needed. In order to imitate ECM, there are materials of natural and
synthetic origin. Gelatin, collagen, chitosan, and fibrin are natural
polymers or hydrogels used with the FDM method to reconstruct a
bone-imitating scaffold [58, 59]. Organic scaffolds that exist in synthetic
form usually include a mixture of gelatin and methacrylate (GelMA),
polyethylene glycol (PEG), and alginate, which are also mainly prepared
by the FDM method [60, 61]. Bone-like mineral tissue is mainly
composed of tricalcium phosphate (TCP), hydroxyapatite (HA), or
composite of a polymer along with TCP or HA [62, 63].
As mentioned above, another category of CAD/CAM application in
bone reconstruction surgery is in situ bone regeneration through
preserving a protected healing space. In this method, there is a need to
preserve a protected healing space, so that the body can generate bone
in that space. To make this guided or protected healing space in the
CAD-CAM method, the material of the membrane is usually titanium,
and the method of choice, SLM [64, 65].
All fields of applied modern technologies and application of
CAD/CAM in the field of oral and maxillofacial surgery are furtherly
discussed in the following chapters.
References
1. Watanabe Y, Dasher RB. On the progress of industrial revolutions: a model to
account for the spread of artificial intelligence innovations across industry.
Kindai Manag Rev. 2020;8:113–23.
2.
Xu M, David JM, Kim SH. The fourth industrial revolution: opportunities and
challenges. Int J Finance Res. 2018;9(2):90–5.
3.
Prisecaru P. Challenges of the fourth industrial revolution. Knowl Horiz Econ.
2016;8(1):57.
4.
Abdulla MA, Ali H, Jamel RS. CAD-CAM technology: a literature review. Al-
Rafidain Dent J. 2020;20(1):95–113.
5.
Vyas K, Gibreel W, Mardini S. Virtual surgical planning (VSP) in
craniomaxillofacial reconstruction. Facial Plast Surg Clin North Am.
2022;30(2):239–53.
[PubMed]
6.
Shenaq DS, Matros E. Virtual planning and navigational technology in
reconstructive surgery. J Surg Oncol. 2018;118(5):845–52.
[PubMed]
7.
Pucci R, Priore P, Manganiello L, Cassoni A, Valentini V. Accuracy evaluation of
virtual surgical planning (VSP) in orthognathic surgery: comparison between
CAD/CAM fabricated surgical splint and CAD/CAM cutting guides with PSI. J
Oral Maxillofac Surg. 2019;77(9):e4–5.
8.
Farajpour H, Bastami F, Bohlouli M, Khojasteh A. Reconstruction of bilateral
ramus-condyle unit defect using custom titanium prosthesis with preservation of
both condyles. J Mech Behav Biomed Mater. 2021;124:104765.
[PubMed]
9.
Unsal G-S, Turkyilmaz I, Lakhia S. Advantages and limitations of implant surgery
with CAD/CAM surgical guides: a literature review. J Clin Exp Dent.
2020;12(4):e409.
[PubMed][PubMedCentral]
10.
Cassetta M, Altieri F, Di Giorgio R, Barbato E. Palatal orthodontic miniscrew
insertion using a CAD-CAM surgical guide: description of a technique. Int J Oral
Maxillofac Surg. 2018;47(9):1195–8.
[PubMed]
11.
Khojasteh A, Bastami F, Alikhasi M. Implant-assisted orthognathic surgery. In:
Integrated procedures in facial cosmetic surgery. Cham: Springer; 2021. p. 687–
702.
12.
Nokhbatolfoghahaei H, Bastami F, Farzad-Mohajeri S, Rezai Rad M, Dehghan MM,
Bohlouli M, et al. Prefabrication technique by preserving a muscular pedicle
from masseter muscle as an in vivo bioreactor for reconstruction of mandibular
critical-sized bone defects in canine models. J Biomed Mater Res B Appl
Biomater. 2022;110(7):1675–86.
[PubMed]
13.
Baldaniya L, Patel B. Computer-assisted manufacturing of medicines. Computer
aided pharmaceutics and drug delivery. Cham: Springer; 2022. p. 153–87.
14.
Chlebus E, Kozera M, Trześniowski T. CAD/CAM systems integration. Zesz Nauk
Politech Śl Mech. (117):87–92.
15.
Kumar V, Isanaka BR, Gupta S, Kushvaha V. Future trends and technologies in
additive and subtractive manufacturing. Additive and subtractive manufacturing
of composites. Cham: Springer; 2021. p. 227–47.
16.
Praveena B, Lokesh N, Buradi A, Santhosh N, Praveena B, Vignesh R. A
comprehensive review of emerging additive manufacturing (3D printing
technology): methods, materials, applications, challenges, trends and future
potential, vol. 52. Mater Today; 2021. p. 1309–13.
17.
Gibson I, Rosen DW, Stucker B, Khorasani M, Rosen D, Stucker B, et al. Additive
manufacturing technologies. Cham: Springer; 2021.
18.
Guo N, Leu MC. Additive manufacturing: technology, applications and research
needs. Front Mech Eng. 2013;8(3):215–43.
19.
Yee S. Transoral robotic surgery. AORN J. 2017;105(1):73–84.
[PubMed]
20.
Dutta SR, Passi D, Sharma S, Singh P. Transoral robotic surgery: a contemporary
cure for future maxillofacial surgery. J Oral Maxillofac Surg Med Pathol.
2016;28(4):290–303.
21.
Liu H-H, Li L-J, Shi B, Xu C-W, Luo E. Robotic surgical systems in maxillofacial
surgery: a review. Int J Oral Sci. 2017;9(2):63–73.
[PubMed][PubMedCentral]
22.
Peacock ZS, Aghaloo T, Bouloux GF, Cillo JE Jr, Hale RG, Le AD, et al. Proceedings
from the 2013 American Association of Oral and Maxillofacial Surgeons
Research Summit. J Oral Maxillofac Surg. 2014;72(2):241–53.
[PubMed]
23.
de Peppo G, Thomsen P, Karlsson C, Strehl R, Lindahl A, Hyllner J. Human
progenitor cells for bone engineering applications. Curr Mol Med.
2013;13(5):723–34.
[PubMed]
24.
Nokhbatolfoghahaei H, Rad MR, Khani M-M, Nadjmi N, Khojasteh A. Application
of bioreactors to improve functionality of bone tissue engineering constructs: a
systematic review. Curr Stem Cell Res Ther. 2017;12(7):564–99.
[PubMed]
25.
Nokhbatolfoghahaei H, Bohlouli M, Paknejad Z, Rad RM, Amirabad ML, Salehi-
Nik N, et al. Bioreactor cultivation condition for engineered bone tissue: effect of
various bioreactor designs on extra cellular matrix synthesis. J Biomed Mater
Res A. 2020;108(8):1662–72.
[PubMed]
26.
Nokhbatolfoghahaei H, Paknejad Z, Bohlouli M, Rezai Rad M, Aminishakib P,
Derakhshan S, et al. Fabrication of decellularized engineered extracellular matrix
through bioreactor-based environment for bone tissue engineering. ACS Omega.
2020;5(49):31943–56.
[PubMed][PubMedCentral]
27.
Somasekharan TL, Kasoju N, Raju R, Bhatt A. Formulation and characterization of
alginate dialdehyde, gelatin, and platelet-rich plasma-based bioink for
bioprinting applications. Bioengineering (Basel). 2020;7(3):108.
28.
Murphy SV, Atala A. 3D bioprinting of tissues and organs. Nat Biotechnol.
2014;32(8):773–85.
[PubMed]
29.
Kothai P, Subudhi SK, Padhiary S, Lenka S, Pal KS, Choudhury BK. Application of
CAD-CAM in Oral and maxillofacial surgery: a literature review. Indian J Public
Health Res Devel. 2019;10(11):1287.
30.
Jamali J, Kolokythas A, Miloro M. Clinical applications of digital dental
Technology in Oral and Maxillofacial Surgery. Clinical applications of digital
dental technology. Hoboken, NJ: Wiley; 2015. p. 207.
31.
Markiewicz MR, Farrell B, Shanti RM. Technology in oral and maxillofacial
reconstruction. In: Peterson’s principles of oral and maxillofacial surgery. Cham:
Springer; 2022. p. 1455–532.
32.
Sukegawa S, Kanno T. Computer-assisted navigation surgery in Oral and
maxillofacial surgery. In: Oral and maxillofacial surgery for the clinician. Cham:
Springer; 2021. p. 841–62.
33.
Rad MR, Fahimipour F, Dashtimoghadam E, Nokhbatolfoghahaei H, Tayebi L,
Khojasteh A. Osteogenic differentiation of adipose-derived mesenchymal stem
cells using 3D-printed PDLLA/β-TCP nanocomposite scaffolds. Bioprinting.
2021;21:e00117.
34.
Khojasteh A, Nadjmi N. Future trends in alveolar cleft osteoplasty. Integrated
procedures in facial cosmetic surgery. Cham: Springer; 2021. p. 525–33.
35.
Nyberg EL, Farris AL, Hung BP, Dias M, Garcia JR, Dorafshar AH, et al. 3D-printing
technologies for craniofacial rehabilitation, reconstruction, and regeneration.
Ann Biomed Eng. 2017;45(1):45–57.
[PubMed]
36.
Myers PL, Nelson JA, Rosen EB, Allen RJ Jr, Disa JJ, Matros E. Virtual surgical
planning for oncologic mandibular and maxillary reconstruction. Plast Reconstr
Surg Glob Open. 2021;9(9):e3672.
[PubMed][PubMedCentral]
37.
Dreizin D, Nam AJ, Hirsch J, Bernstein MP. New and emerging patient-centered
CT imaging and image-guided treatment paradigms for maxillofacial trauma.
Emerg Radiol. 2018;25(5):533–45.
[PubMed]
38.
Ismail MB, Darwich K. Reconstruction of large mandibular bone defects extended
to the condyle using patient-specific implants based on CAD-CAM technology
and 3D printing. Adv Oral Maxillofac Surg. 2022;5:100229.
39.
Schneider D, Kämmerer PW, Hennig M, Schö n G, Thiem DG, Bschorer R.
Customized virtual surgical planning in bimaxillary orthognathic surgery: a
prospective randomized trial. Clin Oral Investig. 2019;23(7):3115–22.
[PubMed]
40.
Jaisinghani S, Adams NS, Mann RJ, Polley JW, Girotto JA. Virtual surgical planning
in orthognathic surgery. Eplasty. 2017;17:ic17.
[PubMed][PubMedCentral]
41.
Kalman L. 3D printing in dentistry: fundamentals, workflows and clinical
applications. In: Advances in dental implantology using nanomaterials and allied
technology applications. Cham: Springer; 2021. p. 325–51.
42.
D’Souza KM, Aras MA. Applications of CAD/CAM technology in dental implant
planning and implant surgery. In: Advances in dental implantology using
nanomaterials and allied technology applications. Cham: Springer; 2021. p. 247–
86.
43.
Bansal A, Bansal V, Popli G, Keshri N, Khare G, Goel S. Robots in head and neck
surgery. J Appl Dent Med Sci. 2016;2:168–75.
44.
Jockusch J, Ö zcan M. Additive manufacturing of dental polymers: an overview on
processes, materials and applications. Dent Mater J. 2020;2019-123:345.
45.
Nyirjesy SC, Heller M, von Windheim N, Gingras A, Kang SY, Ozer E, et al. The role
of computer aided design/computer assisted manufacturing (CAD/CAM) and 3-
dimensional printing in head and neck oncologic surgery: a review and future
directions. Oral Oncol. 2022;132:105976.
[PubMed]
46.
Tarsitano A, Battaglia S, Ramieri V, Cascone P, Ciocca L, Scotti R, et al. Short-term
outcomes of mandibular reconstruction in oncological patients using a
CAD/CAM prosthesis including a condyle supporting a fibular free flap. J Cranio-
Maxillofac Surg. 2017;45(2):330–7.
47.
Helal MH, Hendawy HD, Gaber RA, Helal NR, Aboushelib MN. Osteogenesis
ability of CAD-CAM biodegradable polylactic acid scaffolds for reconstruction of
jaw defects. J Prosthet Dent. 2019;121(1):118–23.
[PubMed]
48.
Cucchi A, Bianchi A, Calamai P, Rinaldi L, Mangano F, Vignudelli E, et al. Clinical
and volumetric outcomes after vertical ridge augmentation using computer-
aided-design/computer-aided manufacturing (CAD/CAM) customized titanium
meshes: a pilot study. BMC Oral Health. 2020;20(1):1–11.
49.
Tan ET, Ling JM, Dinesh SK. The feasibility of producing patient-specific acrylic
cranioplasty implants with a low-cost 3D printer. J Neurosurg.
2016;124(5):1531–7.
[PubMed]
50.
Haleem A, Javaid M. Polyether ether ketone (PEEK) and its manufacturing of
customised 3D printed dentistry parts using additive manufacturing. Clin
Epidemiology Glob Health. 2019;7(4):654–60.
51.
Honigmann P, Sharma N, Okolo B, Popp U, Msallem B, Thieringer FM. Patient-
specific surgical implants made of 3D printed PEEK: material, technology, and
scope of surgical application. Biomed Res Int. 2018;2018:1.
52.
Mazzoli A. Selective laser sintering in biomedical engineering. Med Biol Eng
Comput. 2013;51(3):245–56.
[PubMed]
53.
Dang RR, Mehra P. Alloplastic reconstruction of the temporomandibular joint. J
Istanb Univ Fac Dent. 2017;51(3 Suppl 1):S31.
[PubMed][PubMedCentral]
54.
Fernandes N, Van den Heever J, Hoogendijk C, Botha S, Booysen G, Els J.
Reconstruction of an extensive midfacial defect using additive manufacturing
techniques. J Prosthodont. 2016;25(7):589–94.
[PubMed]
55.
Pacifici L, De Angelis F, Orefici A, Cielo A. Metals used in maxillofacial surgery.
Oral Implantol. 2016;9(Suppl 1/2016 to N 4/2016):107.
56.
Attarilar S, Ebrahimi M, Djavanroodi F, Fu Y, Wang L, Yang J. 3D printing
technologies in metallic implants: a thematic review on the techniques and
procedures. Int J Bioprint. 2021;7(1):306.
[PubMed]
57.
Maroulakos M, Kamperos G, Tayebi L, Halazonetis D, Ren Y. Applications of 3D
printing on craniofacial bone repair: a systematic review. J Dent. 2019;80:1–14.
[PubMed]
58.
Polo-Corrales L, Latorre-Esteves M, Ramirez-Vick JE. Scaffold design for bone
regeneration. J Nanosci Nanotechnol. 2014;14(1):15–56.
[PubMed][PubMedCentral]
59.
Kim HD, Amirthalingam S, Kim SL, Lee SS, Rangasamy J, Hwang NS. Biomimetic
materials and fabrication approaches for bone tissue engineering. Adv Healthc
Mater. 2017;6(23):1700612.
60.
Chen Y, Li W, Zhang C, Wu Z, Liu J. Recent developments of biomaterials for
additive manufacturing of bone scaffolds. Adv Healthc Mater.
2020;9(23):2000724.
61.
Qu M, Wang C, Zhou X, Libanori A, Jiang X, Xu W, et al. Multi-dimensional printing
for bone tissue engineering. Adv Healthc Mater. 2021;10(11):2001986.
62.
Zhao L, Liang L. Materials comparison of 3D printed scaffolds for bone tissue
engineering applications.
63.
Safinsha S, Ali MM. Composite scaffolds in tissue engineering. Mater Today.
2020;24:2318–29.
64.
Ciocca L, Fantini M, De Crescenzio F, Corinaldesi G, Scotti R. Direct metal laser
sintering (DMLS) of a customized titanium mesh for prosthetically guided bone
regeneration of atrophic maxillary arches. Med Biol Eng Comput.
2011;49(11):1347–52.
[PubMed]
65.
Sumida T, Otawa N, Kamata Y, Kamakura S, Mtsushita T, Kitagaki H, et al. Custom-
made titanium devices as membranes for bone augmentation in implant
treatment: clinical application and the comparison with conventional titanium
mesh. J Cranio-Maxillofac Surg. 2015;43(10):2183–8.
© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023
A. Khojasteh et al. (eds.), Emerging Technologies in Oral and Maxillofacial Surgery
https://doi.org/10.1007/978-981-19-8602-4_2
1 Introduction
The invention of advanced imaging such as computed tomography (CT) and
magnetic resonance imaging (MRI) has revolutionized the medical and dental
treatments. The oral and maxillofacial region has a complex anatomy due to the
presence of various critical organs, such as the nerves, vessels, teeth, eye, and
brain. Serving as the third eye, three-dimensional imaging modalities provide
accurate details on hard and soft tissue, anatomic land marks, variations,
abnormalities, and pathologies of the maxillofacial region [1].
Since the development of the first medical CT scanners in 1960s, various
generations have been introduced, each producing higher impact in the
diagnosis and treatment plans. The fundamental principles of CT, whether
applied to multidetector computed tomography (MDCT) or CBCT, are the same:
a collimated x-ray source and detector, mounted in a fixed or rotating gantry,
turn around the patient’ head [2]. During this rotation, the X-ray beam is
attenuated, the remnant photons are captured by the detector, and further
reconstruction algorithms mathematically and spatially process this
attenuated data into a 3D map (Fig. 1).
Fig. 1 Cone beam imaging geometry. A divergent cone beam X-ray is projected from the tube
head and is directed to the detector. The machine continues evolving around the object for the
entire 360° or along a reduced or partial trajectory
The initial CTs, also known as the first-generation CT scanners, used a
pencil-shaped X-ray beam and a single-array detector, with a translate rotate
function, and required a 5-min scan time. Subsequently, the CT scanner design
evolved through four generations, decreasing scan time to 1–2 s. In the late
1990s, MDCT or multislice CT (MSCT) was introduced, having 64–640 detector
rows; this technology has now become the most widely used CT scanner
design. This technology has considerably reduced scan times, which is an
important factor in reducing motion artifacts especially in pediatric, trauma, or
elderly patients [3].
In 1980s, CBCT was originally developed in angiography, and in the early
2000s, this modality was introduced in dental and maxillofacial 3D imaging.
While CBCT is used for many purposes including routine oral and maxillofacial
surgical treatments, like extraction of the mandibular third molars and removal
of impacted teeth and placement of dental implants, with expanding
availability of a third-party application software capable of importing data in
Digital Imaging and Communications in Medicine (DICOM) format, the role of
maxillofacial CBCT has now expanded in a broad range of 3D printing
procedures of models and surgical guides for jaw or facial reconstruction.
In the 1980s, MRI was developed and entered practical clinical diagnosis. In
this noninvasive technique, the patient is placed in a large magnet.
Radiofrequency (RF) pulse is directed to the tissue, and the volumetric data is
produced based on a map of the distribution of hydrogen and local tissue
properties that influence the strength of the magnetic resonance signal. To
accurately assess maxillofacial soft tissues, MRI can provide three-dimensional
views and even provide soft tissue prosthesis using additive manufacturing
techniques [4].
CBCT and MRI data acquisition as a basis for computer-assisted
maxillofacial treatments is further discussed in this chapter, focusing on their
operating principles and clinical applications.
Table 1 Comparison of effective dose from CT examinations. Note the higher effective dose
of MDCT compared to CBCT
CBCT cone beam computed tomography, d days, FOV field of view, M month,
MDCT multidetector computed tomography, msv millisievert, μSv micro-sievert
Currently, there are 279 CBCT models from 47 manufactures available
commercially with applications not limited to the skull, such as cardiac
imaging, radiotherapy, extremities, and peripheral bone imaging (Table 2).
Maxillofacial CBCT units can be classified according to the orientation of
patient during image acquisition: standing, seated, and supine (Fig. 2) [6].
Standing units, like a panoramic machine, are the most common type; however,
these units are prone to motion artifacts and cannot be adjusted for lower
heights especially in disabled patients in wheelchair. Supine units, such as
NewTom 7G (Verona, Italy), provide higher patient stability and greatly reduce
patient motion artifacts. In addition, these types of units allow accurate
assessment of airway, especially in micro-gnathic patients with obstructive
sleep apnea. However, supine units are physically large with a bigger footprint
consuming more area. In all settings, the patient’s head should be completely
immobilized.
Table 2 Selected maxillofacial CBCT machines available with large detector size, providing
large FOV for craniofacial assessments. Note that large FOVs generally have lower spatial
resolutions compared to small FOVs
Fig. 5 Automatic segmentation. (a) Segmentation of paranasal sinuses and airways using
OnDemand application (Cybermed, Seoul, Korea). (b) Segmentation of maxillofacial area to
maxilla (yellow), mandible (green), teeth (white), and airway (teal) using Diagnocat
application (Diagnocat Inc., USA). This masking process results in better visualization of the
maxillofacial area and can provide ready-made models for printing on a 3D printer
Fig. 8 Serial CBCT scans captured form a patient in need of dental implant in the posterior
left maxilla. (a) Preoperative CBCT scan indicated alveolar resorption and sinus
pneumatization. The patient needs sinus lift and bone graft. (b) One-month postoperative
CBCT scan from the same segment after placement of bone graft shows ridge augmentation to
16.68 mm, note the presence of reactive mucosal thickening (arrows). (c) Six-month
postoperative CBCT scan shows reduction in mucosal thickening and slight graft height
shrinkage at the same cross-sectional view
CBCT has a major role in computer-assisted surgeries (CAS) and additive
manufacturing (AM). The obtained volumetric data can be used in the two
main categories: computer-assisted presurgical planning and navigation (See
chap “Data Storing and Conversion in Computer-Assisted Oral and Maxillofacial
Treatments”) [12]. Computer-assisted presurgical planning includes
preoperative surgical simulation with 3D images (Fig. 9) or models (Fig. 10).
Preoperative surgical simulations with 3D images are used to determine the
appropriate position, angulation, and size of dental implants noting the ridge
anatomy, quality, and landmarks prior to insertion [13].
Fig. 9 Cone beam computed tomography scan of fully edentulous patient coupled with a 3D
printed denture prosthesis model indicating sites of crowns with radiopaque material. (a)
Axial, (b) reformatted panoramic, (c) cross-sectional, and (d) 3D surface rendering views
show virtual implant insertion in the anterior maxilla and mandible, indicating the possibility
of buccal thread exposure in the maxilla if placed in the ideal inclination, identifying the need
for buccal bone augmentation prior to implant placement
Fig. 10 Coronal (a), axial (b) and sagittal (c) DICOM data from CBCT is converted to the
Standard Tessellation Language (TSL) format. A 3D model (d) is provided prior to an orbital
wall reconstruction in a patient with severe trauma to the left side of the face, with multiple
fractures in the zygoma, orbit, and frontal bone. The 3D prostheses (pink, orange, and blue) are
designed to reconstruct the traumatic sites. (Mimics research 21.0, Materialise NV, Leuven,
Belgium)
Recent advances in the fields of computer-assisted orthognathic surgery
planning and resection surgeries, due to the presence of intrabony pathologic
lesions, use software incorporating the DICOM (Digital Imaging and
Communications in Medicine) data from CBCT and have provided a valuable
tool assisting in the diagnosis, treatment planning, and evaluation of treatment
outcomes of maxillofacial deformities [1]. CBCT is by far the most used
modality for digitizing CAD models for AM purposes for 3D bone imaging, as
bone provides an excellent contrast and allows for high spatial accuracy to be
pursued by utilizing “sharp” reconstruction kernels [14]. (Fig. 10).
Fig. 11 MRI imaging. (a) Coronal T1-weighted, (b) sagittal T2-weighted, and (c) axial T2-
weighted images of maxillofacial region. Note that air and cortical bone are signal void
Based on the detected signal intensity in T1 and T2 MRI images, one can
assume the normal and abnormal anatomy in the maxillofacial region. Tissue
intensity can be categorized into signal void (cortical bone, enamel, dentin, air,
metallic artifacts), low (lower than the intensity of muscles), intermediate
(between muscle and fat signal), and high (same or higher than fat) (Fig. 12).
Fig. 12 Sagittal three Tesla T2 MRI. Note that the air in maxillary sinus, cortical bone,
enamel, and dentin are presented as signal voids. The pulp and root canal system are
presented in higher signal due to the presence of vessels and nerves
Author: H. B. Fyfe
Language: English
By H. B. FYFE
Illustrated by ORBAN
On the second morning after the arrival of Trent and Miss Norsund,
Guthrie judged the time ripe for a longer talk.
When he and Polf approached the hut in which the newcomers were
quartered, signs of obstructionism appeared; but the spacer sneered
them down. By the time he found himself seated on the ground
facing Trent and the girl, the onlookers had been reduced to Polf and
a trio of glum guards. The former seemed to take pleasure in his
comrades' loss of face.
"Sorry I took so long," Guthrie apologized. "There's a certain act you
have to put on around here. They been treating you all right?"
He looked at the girl as he spoke, reflecting that a little cleaning up
had improved her immeasurably. With the mud off, she displayed a
glowing complexion and a headful of chestnut curls; and Guthrie was
no longer sure she was too thin. He determined to check the first
time she stood up in the short, borrowed dress of Skirkhi leather.
"Look here, Guthrie—that is your name, isn't it?" Trent asked
peevishly.
"That's right. Pete Guthrie, currently employed, I hope, by the
Galactic Survey. And you two are Trent and Norsund?"
"George Trent and Karen Norsund, yes. But what I want to say is
that we find your attitude very strange. How can we expect co-
operation from the natives if you throw your weight around the way
you do?"
"And what," asked Karen Norsund, turning her big gray eyes on
Guthrie, "was that remark about the natives saving you from
something?"
"It's for something. I think I'd better tell you the local superstitions."
"If you don't mind," Trent interrupted, "I'd rather know how far it is to
a Terran settlement. We tried to treat the crowd like humans after
you left, but we'd prefer not to stay here until a rescue ship arrives."
"As far as I know," said Guthrie, "we are the only Terrans on this
planet."
He watched that sink in for a few moments, then explained how the
system had fallen within the volume of space allotted to him for
general survey, how it had never before aroused any great interest
beyond being noted in the Galactic Atlas for the benefit of space
travelers in just such a situation as theirs.
"I hope your rocket is in good shape," he finished. "Did you land
well?"
"Oh ... well enough," said Trent. "What about it? Why not stay here
until we think a rescue ship is near, then go back and televise for
help?"
"It's not that easy," said Guthrie. "If this ship we're hoping for stops to
scout for other survivors, we'll be in a real unhealthy situation."
They looked puzzled.
"The seasons here," he explained, "tend to wild extremes. They have
tidal waves you wouldn't believe. In a few weeks, the storms will
begin and the Skirkhi will go to the hills to dig in. It's a bad time to be
caught in the open."
"Oh, come, man!" Trent snapped. "We shouldn't be here that long."
"It's only two or three weeks. The trouble is that on a certain night
shortly before they leave the village to the mercy of the sky spirits,
the Skirkhi have a nasty custom—"
"I don't care about your low opinion of the local customs," interrupted
Trent. "From what I've seen of you, Guthrie, it is obvious that you are
not the sort to represent Terra on the frontiers. Just tell me—if you
can't get along with the natives like a civilized being, where do you
expect to get?"
"Up to Jhux," said Guthrie.
"Where?"
"Jhux, the largest moon. It has a thin atmosphere. We could pump
enough air into your rocket to live on, and wait to signal any
approaching ship."
"But why go to all that trouble?"
"Besides," Karen Norsund put in, "I think I've had enough travel in a
small rocket for the time being."
"It'll be better than the hurricanes here," Guthrie sighed. "Now, if
you'll just let me finish about the Skirkhi—"
Trent screwed up his face in exasperation until his eyes were slits
above his cheekbones. He shrugged to Karen in a way that turned
Guthrie's neck red.
"All right!" the latter choked out. "You seem to want to make me look
narrow-minded! Wait till you know the Skirkhi! They believe very
seriously in these sky spirits. They try to buy them off, to save the
village and their own skins—and they pay in blood!"
He waited for the shocked exclamations, the suspicion, then the
exchange of glances that agreed to further consideration.
"Until you two came along, I was the goat. Now there are three of us
to choose from, but your rocket gives us the means to make a run for
it."
They thought that over for a few minutes.
"How do you know they won't ... use ... all three of us?" shuddered
Karen.
"The Skirkhi have learned to be frugal. They'll save something for
next season. Otherwise, they'd have to raid some other tribe or elect
one of them."
"But, before then, either a rescue ship or one from the Survey will
have arrived, don't you think?" suggested Trent.
"What are you getting at?"
"Well ... this: assuming that you are not exaggerating your distrust of
the natives, if they actually feel it necessary to ... er ... sacrifice to
these sky spirits, that will still leave the remaining two of us a good
chance."
Guthrie wiped a hand slowly over his face. He glanced out of the
corner of his eye at Polf and the Skirkhi guards, wondering if they
could guess the drift of the conversation.
"And what will your next idea be?" he demanded bitterly. "Want us to
draw straws to see which of us goes out and commits hara-kiri for
them?"
"Now, now! We must be realistic. After all, nothing serious may come
of this. Merely because you and the natives share a mutual antipathy
—"
"You make me sick!" growled Guthrie, rising to his feet.
"I don't know what you mean."
"But I know what you're figuring," said the spacer. "The excuse will
be that you're willing to take your chance with the Skirkhi choice, or
that you don't want to stir up trouble because of the girl; but actually
you think I'm the natural candidate!"
"Mr. Guthrie!" exclaimed Karen, jumping up.
"Pardon me! I have to go and commune with the spirits of the sky!"
He pivoted toward the street and bounced off one of the guards who
had crept closer to eavesdrop. Automatically, he shoved the Skirkh
into the wall.
Behind him, he heard a muttered curse in Skirkhi, then another thud
as a thick skull clunked yet again into the wall. He deduced that Polf
was following both his footsteps and his example.
They walked out toward the hill where he and Polf had sat the day
the rocket had flared down from the sky. Two pale crescents hovered
on the horizon.
"There will still be Yiv in the night," muttered Polf, "but soon he will
follow Jhux and there will be no moon. Then come storms."
Guthrie recalled his surprise at the natives' awareness of Yiv, a small
satellite whose distance made it appear merely an enormous star.
He had noted it from space, but they must have realized its nature
from regular observation.
They walked a few minutes, when Polf peered slyly at him.
"I think these sky ones good spirits, not like you."
"What do you mean?" asked the other suspiciously.
"When in hard talk, you get red in face almost like human. They not.
The she-spirit a little, yes. But the other ... I think he is best spirit of
all!"
"Aw, what do you know about Terrans?" demanded Guthrie
uncertainly.
"What are Terrans?" Polf leered at the effort to take him in by a trick
name. "You, Gut'rie, you act like us. You learn fear evil spirits like
smart man. Maybe was trick of good ones—send you here so we
make mistake."
Guthrie stared down at the stocky Skirkh, trying to follow that chain
of thought and wondering how many in the village would find it
logical.
Most of them, I'm afraid, he thought. I wonder ... what if I just kept
quiet and let him dig his own grave? If I read Trent right, he'll do it!
They sat for a while on the crest of the low hill, in the warmth of the
sun. Polf seemed not to mind Guthrie's brooding. Patience was a
Skirkhi forte. At times, the spacer pitied the natives, with their harsh
and precarious life.
Maybe something could be done here, he reflected. A good,
thorough survey would tell. After all, G. S. engineers have controlled
temperatures on some planets by diverting a few ocean currents.
And there's cloud-seeding....
"Huh!" he grunted. "Already thinking as if I were safe on Jhux."
He began to question Polf as to what the search party had reported,
and derived a good idea of the route to the rocket. Tortuous details of
Skirkhi trail directions baffled him every few minutes, so that it was
twilight before he was satisfied that he could find the craft on his
own. With Polf trailing, he strolled thoughtfully to his quarters,
bracing for supper of fish or lizard.
At intervals during the next three days, he saw the new couple about
the village. Trent, especially, did not seem eager to speak to him,
and they were always accompanied by at least one Skirkhi couple.
In a moment of relaxation, Guthrie permitted himself to observe
Karen with pleasure, when she appeared in her own clothes. With
the mud washed out, it became apparent that she had been wearing
a smart pair of lounging pajamas when interrupted by the
spaceliner's alarm.
Trent had also cleaned his sport shirt and baggy slacks, and now
went about making himself buoyantly pleasant to the natives. Once
or twice, turning away from this spectacle with a frown, Guthrie
chanced to encounter the black, analytical stare of old Thyggar. A
sardonic grin quirked the elder's wide mouth.
"Retho tell me Trent learn speak Skirkhi fast," Polf reported, glittering
eyes nearly hidden by the contortion that passed for a smile on
Skirkhi faces, "so he can tell what a good man he is. He says is kind.
He says is friend. You would laugh, Gut'rie—he call you names!"
"So will he laugh," growled Guthrie, "on the other side of his face.
He's begging for it, all right."
He chewed his lip for a moment, then shrugged. With a nod to Polf,
he started down the street to the huts assigned to Trent and Karen.
He found the girl behind the squat stone house, doing her best to
comb out a mop of freshly washed chestnut hair.
"You'd do better to leave some mud in it," he advised her.
This drew a hard gray stare. Guthrie turned to Polf.
"Can't you do something with this one sitting beside her?" he
demanded.
Polf grinned, showing a sturdy set of broad teeth.
"It would be like sacrifice to those who sent down these others," he
said. "Last night, when leaving Retho at your door, I kill chivah lizard
in street. With club. But was only a little blood and we are full of
thanks."
After a few minutes of conversation under the glowering gaze of the
Terran girl, he enticed the Skirkhi woman around the corner toward
the entrance of the hut. Guthrie turned to Karen.
"Listen!" he said urgently. "What is this I hear about Trent going
around like a cock-eyed good-will ambassador?"
"I can't help what he does," Karen said defensively. She had trouble
meeting his eye. "I told him I didn't think he should talk that way, but
he said ... well ... that you—"
"I can imagine," said Guthrie. "Well, he'd better stop it, and not on my
account. This is a queer, dangerous place."
He took a few steps to the corner of the hut, to check that the space
between adjoining houses was empty of spies. The guards loitered
in the street.
"It may sound strange," he continued, "but it makes a distorted kind
of sense for people who live on a planet like Boyd III—this belief in
sky spirits. I told you about the bad season, I think, and the uproar
raised by coinciding tides."
Karen, having brushed her hair into some sort of order, eyed him
watchfully.
"I would expect them to protect themselves from the rains," she
remarked.
"Rains!" snorted Guthrie. "You don't know! Hurricanes! Tidal waves!
Floods! They lose people every storm. This is a very bad place to
live. So what do you suppose they worship?"
"Sky spirits, you keep telling me."
"Yes," he said, lowering his voice instinctively. "But not good ones,
naturally—spirits of evil."
Karen looked at him sidelong and clucked her tongue.
"It's not funny; it's perfectly logical. They spend their lives one jump
ahead of freezing or drowning. Their world's against them. Other
savage races have figured it that way, even on Terra."
"All right, it's logical. What has it to do with us?"
"It has this to do," said Guthrie. "That clown, Trent, is going around
making friends like a puppy. He's cutting his own throat, an' I'd bet he
thinks he's cutting mine. But you don't think they'd sacrifice a bad
person, do you?"
The thought penetrated, and she rose slowly to her feet. He reached
out to her shoulders and gave her a little shake.
"The Skirkhi spend weeks before the stormy season making sure the
evil spirits notice what nasty people they are. Like Terran kids before
Christmas, in reverse. And there's that apple-polisher making a
gilded saint of himself while the natives are spitting in their friends'
faces and trying to steal their wives or cheat old Thyggar on their
taxes."
The girl stared at him in horror. The flesh of her shoulders was soft
but firm under his fingers. He suddenly wished there were no Skirkhi
hanging about.
Suddenly, Karen's gray eyes widened with a new wariness.
"Let go!" she ordered.
"Maybe I shouldn't," Guthrie teased her. "Maybe I ought to let the
Skirkhi see that you have claws. It would help your reputation here."
She began to struggle, and he had a hard time holding her but
somehow hated to let go. He was conscious of a padding of feet in
the alleyway as a couple of guards drifted in from the street.
Karen tried kicking him in the shin, then wound the fingers of one
hand in his hair and yanked. Guthrie, who had by then clasped both
hands in the small of her back, let go with his left to grab her wrist.
Immediately, the nails of her other hand raked past his right eye.
He muttered a curse, let go completely as he felt a sudden fury well
up in him, then grabbed a handful of her long hair in his left hand. He
half raised his other hand, undecided whether to slap or let her go.
She screwed up her face and tried to turn away.
"Guthrie!" shouted a man's voice.
Trent ran between the huts, trailed by a score of Skirkhi.
Well, this ought to be it, thought Guthrie, releasing the girl. He can't
let this pass. I suppose I have a poke in the snoot coming.
Trent hauled Karen aside protectively, frowning at Guthrie. The latter
stood with his hands waist-high, shoulders slightly forward, waiting.
Watching Trent's eyes, he saw them flicker toward the expectant
Skirkhi.
"I realize that there can be only one explanation, Guthrie," said the
other, "but this is obviously neither the time nor place to argue it."
"I didn't offer any explanation," said Guthrie, ashamed but irritated.
"We are being observed," Trent reminded. "Show a little Terran
dignity!"
He raised his chin with dignity and Guthrie punched it as hard as he
could.
Shoving the natives ahead and towing a Karen whose voice showed
signs of turning shrill, he got the group over the crest of the hill in
plenty of time before the sky flared and thundered with the sudden
roar of rockets.
The horrid noise departed toward the upper atmosphere. Presently,
Guthrie's eyes readjusted to the dark until he could make out the
trees through which they had groped and bumped heads an hour
earlier.
"Might as well start," he said. "We might make it back in time for
lunch."
"But the rocket!" wailed Karen. "After that awful trip to find it!"
"I set the controls," he explained, "to blast it up into an orbit around
the planet, where it can broadcast our location until we're picked up."
"Oh," said Karen. "Well, I hope you can handle your friends till then."
"We should be able to see it in a little while. I set the controls to flop
it over when it's high enough and send it around east to west."
"Why?"
"So it will match the apparent motions of the moons."
Karen walked perhaps twenty steps in silence, then stopped dead.
"Guthrie! Do you really mean we can see it?"
"Sure. I did it a bit roughly, but I'm hoping for under two thousand
miles and two or three periods a night. Even when it isn't catching
any sunlight, that beacon ought to show. Dimmer than Yiv, maybe,
but moving and easy to spot."
With the flashlight, making their way through the woods took less
time. They were half-way across a grassy plain when Polf exclaimed
and pointed to the sky. Guthrie whooped.
"There's a moon for tonight!" he yelled. "And every night, for quite
some time, until the pulls of the real ones spoil its orbit."
He felt so good that he threw an arm about Karen's waist. It must
have felt good to her, too, for instead of pulling away, she leaned
closer.
"They'll wait now, won't they?" she asked. "I mean, unless there's no
moon.... Wait till George finds out what you've done for him!"
"I don't know why I'm so good to him when I like the Skirkhi better,"
said Guthrie. "Of course, we can't explain until I think up a suitably
rotten excuse, or it would ruin my reputation with them!"
They stood motionless for a few minutes, watching the bright light
creep perceptibly along its path in the heavens.
"Is it Yiv?" asked Kror, puzzled. "It should not be, now."
"Gah!" exclaimed Polf. "You mud-head! Of course, it is not Yiv. Our
Gut'rie has made a new moon. Be grateful to Polf for bringing you,
for we shall be big in the village after this!"
He looked proudly at Guthrie. The latter turned off the flashlight to
see if the sky were actually beginning to show a pre-dawn lightening.
"We will be very big," Polf repeated. "Are we not friends of the evilest
spirit of them all?"
*** END OF THE PROJECT GUTENBERG EBOOK THE NIGHT OF
NO MOON ***
Updated editions will replace the previous one—the old editions will
be renamed.