Adrenergic Agonists

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1. Student Nurse Aimee is reviewing for her licensure exam.

She would be right


to pick which drug pairing (classification and corresponding example)?

A. alpha1-selective adrenergic blocking agent: phentolamine


B. nonselective adrenergic blocking agent: labetalol
C. nonselective alpha-adrenergic blocking agent: doxazosin
D. nonselective beta-adrenergic blocking agent: metoprolol

1. Answer: B. nonselective adrenergic blocking agent: labetalol

Other examples of nonselective adrenergic blocking agents aside from


labetalol are amiodarone and carvedilol. Phentolamine is a nonselective
alpha blocker. Doxazosin is an alpha1-selective blocker and metoprolol is a
selective beta-blocker.

2. Which of the following drugs can improve urine flow in males?

A. prazosin
B. nebivolol
C. labetalol
D. amiodarone

2. Answer: A. prazosin

Prazosin, a selective alpha1-receptor adrenergic antagonist, can improve


urine flow in male patients and are used as treatment for benign prostatic
hypertrophy (BPH). This is because they can block smooth muscle receptors
in the genitourinary tract which leads to relaxation of prostate and bladder.

3. Nurse Sam is taking care of a patient on carvedilol therapy. Which


parameter should he monitor regularly to assess for possible dose
adjustment?

A. serumsodiumlevel
B. hemoglobin and hematocrit
C. SGPT
D. BUN
3. Answer: C. SGPT

Carvedilol has been associated with hepatic failure related to its effects on the
liver.

4. Mrs. Smith, a40-year-old patient, came in due to acute hypertensive episode.


Her chart says she is asthmatic. Which of the following drugs would be safest to
give?

A. nebivolol
B. timolol
C. propranolol
D. atenolol

4. Answer: D. atenolol

Atenolol is a selective beta-blocker and it does not block the receptors


responsible for bronchodilation. All other options are nonselective beta-blockers
and may cause bronchoconstriction and spasms.

5. Which of the following drug is used for diagnosis of pheochromocytoma?

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A. amiodarone

B. phentolamine

C. tamsulosin

D. acebutolol

5. Answer: B. phentolamine

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