The GEA Niro Pharma Test Station includes two fully equipped GEA Niro

PHARMASD spray dryers type PSD-1 and PSD- 4 for spray drying under cGMP
conditions. The plants are available for spray drying process development and for
manufacturing. Read the brochure on our Pharmaceutical Test Station and the brochure
on pharmaceutical spray drying.



CIick here to see a fuII-screen version of the fIow-sheet.
!Iant configuration
O Main components: Chamber, cyclone, bag filter, HEPA-filters, condenser,
electrical heaters
O Nitrogen as drying gas
O Closed-cycle loop
O Powder collection under cyclone. Bag filter for collecting fines
O Atomization methods:
- Pressure nozzle, co-current
- Two-fluid nozzle, co-current
eed
O Mixing of various solvents possible
O Dosing and mixing of various raw materials possible
O Filtration of feed possible
$oIvents
O Water
O Ethanol
O Methanol
O sopropyl alcohol
O Acetone
O Methylene chloride
O Ethyl acetate
5erating 5arameters
nlet temperature up to 220 C
Outlet temperature up to 150 C
Condenser temperature down to -18 C
Feed temperature 5 C to 80 C
Pressure nozzle, atomization pressure 10 bar to 100 bar
Two-fluid nozzle, gas pressure 0,5 bar to 14 bar
Two-fl uid nozzle, atomization gas temperature 18 C to 100 C
CI!
CP liquid temperature: Up to 80 C
Ca5acity
The PSD-1 spray dryer is a lab size unit with a nominal drying gas rate of 80 kg./h. The
PSD-4 spray dryer is the a full scale production unit with a nominal drying gas rate of
1250 kg./h.