MCQ- ANTI-ANXIETY, SEDATIVE HYPNOTICS

1. Which of the following may

happen when people stop taking an
antianxiety or a sedative drug after
using it for a long time?
a. Anxiety, irritability and sleep
problems
b. Criminal behaviour
c. Muscle weekness
d. None of the above
2. Which of the following is the
antidote for benzodiazepines?
a. Diazepam

b. Activated charcoal

c. Aspirin

d. Flumazinil
e. Barbiturates,exert,the,follo
wing,actions,EXCEPT:,,
f. a. Anticonvulsant--

g. b. Analgesic-

h. c. Antianxiety-

i. d. Respiratory-depressant

j. Barbiturates,exert,the,follo

wing,actions,EXCEPT:,,
k. a. Anticonvulsant--

l. b. Analgesic-

m. c. Antianxiety-

n. d. Respiratory-depressant

o. Barbiturates,exert,the,follo

wing,actions,EXCEPT:,,
p. a. Anticonvulsant--

q. b. Analgesic-
 r. c. Antianxiety-
s. d. Respiratory-depressant-

Barbiturates,exert,the,following,a
ctions,EXCEPT:,,
a. Anticonvulsant--
b. Analgesic-
c. Antianxiety-
d. Respiratory-depressant-
Barbiturates,exert,the,following,a
ctions,EXCEPT:,,
a. Anticonvulsant--
b. Analgesic-
c. Antianxiety-
d. Respiratory-depressant-
3. Barbiturates exhibits the
following actions except
a. Sedative
b. Hypnotic
c. Respiratory depressant
d. Analgesic
e. Benzodiazepines,differ,fro
m,barbiturates,in,the,follo
wing,aspects,EXCEPT:,
f. 
g. ,
h. a. They-have-a-steeper-
dose-response-curve--
i. b. They-have-higher-
therapeutic-index--
j. c. They-have-lower-
abuse-liability--
k. d. They-do-not-induce-
microsomal-drug-
metabolizing-enzymes
l. Benzodiazepines,differ,fro
m,barbiturates,in,the,follo
wing,aspects,EXCEPT:,
m.
n. ,
o. a. They-have-a-steeper-
dose-response-curve--
p. b. They-have-higher-
therapeutic-index--
q. c. They-have-lower-
abuse-liability--
 r. d. They-do-not-induce-
microsomal-drug-
metabolizing-enzymes
4. The primary mechanism of action
of benzodiazepine is
a. Dopamine antagonism
b. Adrenergic antagonism
c. Neuronal cl- channel opening
d. GABA mediated cl- channel
opening
5. Which among the following is a
potent and short acting hypnotic?
a. Flurazepam
b. Nitrazepam
c. Temazepam
d. Triazolam
6. Clonazepam is a benzodiazepine
used as
a. Antiepileptic
b. Muscle relaxant
c. Anxiolytic
d. Sedative
7. Which of the following is a non-
sedative anxiolytic?
a. Chlorpromazine
b. Buspirone
c. Phenobarbitone
d. Alprazolam
8. A _____ is a drug that depresses
the central nervous system,
produces calm and suppresses bodily
reactions, but does not directly
induce sleep
 a. Antidepressant
b. Sedative
c. Hypnotic
d. Anxiolytic
9. Which of the following drugs
increases the duration of open GABA
channels?
a. Barbiturates
b. Zolpidem
c. Benzodiazepines
d. Buspirone
10. Which of the following drugs has
a large impact on hepatic enzymatic
activity?
. Benzodiazepines
B. Flumazenil
 C. Barbiturates
D. Ramelton
11. What receptor do Barbiturates
bind to?
A. GABAb
B. GABAa
C. Glutamate
D. AMPA
12. Which of the following sedatives
can be used clinically for seizures?
A. Lorazepam
B. Pentobarbital
C. Zolpidem
D. Alcohol
13. Which of the following is not one
of the symptoms
Barbiturate/Benzodiazepine
 dependence?
A. CNS excitability
B. Insomnia
C. Seizures
D. Anxiety
14. Which drug only promotes Sleep
but not any of the anxyiolytic
effects?
A. Flumazenil
B. Zolpidem
C. Thiopental
D. Busiprone
15. Which of the anxiolytic drugs are
partial agonists on serotonin and
dopamine receptors?
A. Busipirone
B. Pentobartbital
C. Flumazenil
D. Alcohol