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Mcqs For Frcophth Part 1 1St Edition Sohaib R Rufai Full Chapter PDF
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Sohaib R. Rufai
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MCQs for FRCOphth Part 1
MCQs for FRCOphth Part 1
Impression: 1
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DOI: 10.1093/oso/9780192843715.001.0001
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DEDICATION
Sohaib R. Rufai
ACKNOWLEDGEMENTS
Reviewers
Mr Richard Bowman Consultant Paediatric Ophthalmologist,
Great Ormond Street Hospital for Children, London, UK
Special thanks
I would like to thank the following colleagues for providing figures. Dr
Tania Aslam Rufai, GP Registrar, Kent, for agreeing to be the ‘eye
model’ for the book cover and various images within this book. Mr
Syed Riyaz Ahmad, retired ophthalmologist, Essex, for providing
anatomy illustrations. Mr Umar Ahmed, Medical Student at Imperial
College London, for providing optics ray diagrams and numerous
other schematics. Mr Aswin Chari, Clinical Research Fellow in
Neurosurgery, Great Ormond Street Hospital for Children (GOSH),
for providing neuroimaging figures. Dr Hardeep Singh Mudhar,
Consultant Ophthalmic Pathologist at Royal Hallamshire Hospital, for
providing histopathological images. Mr Dermot F. Roche, Vision
Scientist at GOSH, for performing specialist ophthalmic imaging. Dr
Dorothy Thompson, Consultant Clinical Scientist at GOSH, for
providing electrodiagnostic diagrams. Finally, thank you to Oxford
University Press for publishing this book.
CONTENTS
Abbreviations
Paper 1
Questions
Solutions
Paper 2
Questions
Solutions
Paper 3
Questions
Solutions
Paper 4
Questions
Solutions
Paper 5
Questions
Solutions
Index
ABBREVIATIONS
AI artificial intelligence
AMD age-related macular degeneration
AV atrioventricular
BCC basal cell carcinoma
D dioptre
ECG electrocardiogram
EOG electro-oculogram
ERG electroretinogram
exo exoenzyme
FFA fundus fluorescein angiography
ffERG full-field electroretinogram
FRCOphth Fellowship of the Royal College of Ophthalmologists
GAG glycosaminoglycan
H&E haematoxylin and eosin
HLA human leukocyte antigen
ICD-11 International Classification of Diseases, 11th revision
ICG indocyanine green
IOL intraocular lens
IOP intraocular pressure
LP:DT light peak:dark trough
MCQ multiple-choice question
mgERG multifocal electroretinogram
MRI magnetic resonance imaging
Nd-YAG neodymium–yttrium aluminium garnet
OCT optical coherence tomography
OCTA optical coherence tomography angiography
PAL progressive addition lens
PCR polymerase chain reaction
PERG pattern electroretinogram
POAG primary open-angle glaucoma
prVEP pattern reversal visual evoked potential
RAPD relative afferent pupillary defect
RPE retinal pigment epithelium
RSM relative spectacle magnification
SIGN Scottish Intercollegiate Guidelines Network
SLO scanning laser ophthalmoscopy
UBM ultrasound biomicroscopy
US ultrasonography
VEP visual evoked potential
Paper 1 Questions
Optics 1
1. Which of the following ranges represent the visible
wavelengths of the electromagnetic spectrum, in
nanometres (nm)?
400–780 nm
500–880 nm
600–980 nm
700–1080 nm
Fibreoptic cable
Volk 90-dioptre lens
Fresnel prism
Focimeter
4 dioptres
8 dioptres
16 dioptres
32 dioptres
7.08
7.18
7.33
7.43
8. Regarding hypermetropia, which statement is LEAST likely
to be correct?
Ring scotomas
Jack-in-the-box phenomenon
Heavy lenses
Barrel distortion
Illumination stage
Dark-adaptation stage
Reflex stage
Projection stage
Regarding the Javal–Schiøtz keratometer, which statement
12. is MOST likely to be true?
Anatomy 1
17. Regarding walls of the orbit, which statement is MOST likely
to be true?
The roof comprises the orbital plate of frontal bone and body of
sphenoid.
The floor comprises the orbital plate of maxilla, orbital surface of
zygomatic, and orbital process of palatine.
The lateral wall comprises the zygomatic bone and lesser wing of
sphenoid.
The medial wall comprises the frontal process of maxilla, lacrimal
bone, orbital plate of ethmoid, and greater wing of sphenoid.
Nasociliary
Abducent
Trochlear
Upper division of oculomotor
The central cornea is supplied with oxygen dissolved in the tear film.
The peripheral cornea is supplied with oxygen by diffusion from the
posterior ciliary blood vessels.
The long ciliary nerves provide sensory innervation to the cornea.
Complete turnover of the surface epithelial cells is estimated to take
7 days.
1 mm
5 mm
10 mm
25 mm
Intorsion
Extorsion
Abduction
Adduction
Physiology 1
Physiology of the eye and vision
3.4 μm
6.8 μm
13.4 μm
16.8 μm
Y
V
Inverted Y
Inverted V
34. What is the resting membrane potential of a dark-adapted
rod cell, in millivolts (mV)?
−40 mV
−70 mV
−100 mV
−130 mV
General physiology
Prolactin
Oxytocin
Thyroid-stimulating hormone
Growth hormone
Biochemistry
Oil Red O
Masson trichrome
Alcian blue
Congo red
Type 1 herpes simplex virus can cause dendritic ulceration within the
corneal endothelium.
Primary infection rarely occurs through the oral mucosa.
Complications of herpes simplex infection of the eye include
disciform keratitis and secondary lipid keratopathy.
When reactivated, the virus can produce vesicle formation in the
skin.
Microbiology
15%
25%
35%
45%
Staphylococcus epidermidis
Escherichia coli
Propionibacterium acnes
Staphylococcus aureus
Trematode
Nematode
Cestode
Protozoan
Immunology
57. Which law can predict the rate of diffusion though a cell
membrane?
Fick’s law
Sherrington’s law
Frank–Starling law
Poiseuille’s law
1–2 μL
7–8 μL
15–16 μL
24–25 μL
Adalimumab
Infliximab
Rituximab
Tocilizumab
Genetics
Patau
Klinefelter
Down
Edwards
FOXC1
PAX6
RS1
RB1
Investigations 1
69. When performing the Maddox rod test on a patient with right
exophoria, if the Maddox rod is positioned horizontally in
front of the right eye fixing on a white spot of light, where
will the red line appear?
70. Regarding the cover test, upon covering the right eye, what
is indicated by inward turning of the uncovered left eye to
fix on a target?
Left exotropia
Left esotropia
Left exophoria
Left esophoria
Fluorescein allergy
Shellfish allergy
Renal impairment
Pregnancy
50 milliseconds
75 milliseconds
100 milliseconds
135 milliseconds
Miscellaneous 1
80. Regarding hypothesis testing, which statement is MOST
likely to be true?
The p-value represents the probability that the null hypothesis is
false.
A type II error occurs where the null hypothesis is incorrectly
accepted.
Power is equal to 1 minus the probability of a type I error.
A power of 70% is generally considered acceptable in study design.
CONSORT
STROBE
STARD
PRISMA
Nominal
Ordinal
Binary
Continuous
54
48
34
40
Mann–Whitney U test
Wilcoxon signed rank test
Chi-squared test
McNemar’s test
Analysis of variation
Wilcoxon signed rank test
Kruskal–Wallis test
Fisher’s exact test
Optics 1
1. A.
The visible wavelengths of the electromagnetic spectrum fall between
400 nm and 780 nm.
Further reading
Chapter 1: Properties of light and visual function. In: Elkington AR, Frank HJ,
Greaney MJ. Clinical Optics. Blackwell Science (1999).
2. C.
Radiant intensity is measured in watts per steradian and luminous
intensity is measured in candelas, i.e. lumens per steradian. Other
options are false.
Further reading
Chapter 1: Properties of light and visual function. In: Elkington AR, Frank HJ,
Greaney MJ. Clinical Optics. Blackwell Science (1999).
3. C.
The image formed by the concave mirror where the object lies
outside the centre of curvature is real, inverted, and diminished (RID).
Fig. 1.1a–c displays three ray diagrams for images formed by a
concave mirror, depending on the position of the object. Fig. 1.2
displays a ray diagram for the image formed by a convex mirror.
(a) O outside C; I = real, inverted, diminished (RID).
Further reading
Chapter 2: Reflection of light. In: Elkington AR, Frank HJ, Greaney MJ. Clinical
Optics. Blackwell Science (1999).
4. A.
Fibreoptic cables utilise total internal reflection.
Further reading
Chapter 3: Refraction of light. In: Elkington AR, Frank HJ, Greaney MJ. Clinical
Optics. Blackwell Science (1999).
5. D.
The ×8 loupe possesses a lens power of 32 dioptres and is
commonly used.
Further reading
Chapter 5: Spherical lenses. In: Elkington AR, Frank HJ, Greaney MJ. Clinical
Optics. Blackwell Science (1999).
6. C.
Simple transposition of cylinders:
Step 1. Sum. Add the powers of sphere and cylinder to arrive at new
power of sphere.
Step 2. Sign. Switch the sign of cylinder.
Step 3. Axis. Rotate axis of cylinder through 90°.
Further reading
Chapter 7: Optical prescriptions, spectacle lenses. In: Elkington AR, Frank HJ,
Greaney MJ. Clinical Optics. Blackwell Science (1999).
7. C.
Fig. 1.3 displays Gullstrand’s schematic eye and Table 1.1 displays
distances behind the anterior corneal surface for Gullstrand’s
schematic eye. Table 1.2 displays refractive indices of the eye. Fig.
1.4 displays the reduced eye and Table 1.3 displays distances behind
the anterior corneal surface for the reduced eye.
Figure 1.3 Gullstrand’s schematic eye. Key: P1 = first principal point; P2 = second
principal point; N1 = first nodal point; N2 = second nodal point; F1 = first focal point;
F2 = second focal point.
Figure courtesy of Mr Umar Ahmed, Medical Student, Imperial College London.
Next day Ewen kept his word, and set about his departure. A
garron was found for him to ride, and two of his men who had
followed him through the campaign were to accompany him to the
coast. Yielding to pressure, he had agreed to take young Angus
MacMartin with him to France as his personal servant. He could not
refuse it to Neil’s memory and to old Angus’s prayers that a
MacMartin should be about him still.
He was to leave at dusk, since travelling by night would be less
hazardous, and a little before sundown he went up to Slochd nan
Eun to take leave of his foster-father, with whom he had had little
converse since his return, for Angus had been ill and clouded in
mind. But he had borne the loss of his two sons with an almost fierce
resignation; it seemed as if he had asked no better fate for them,
especially for Neil. He had recovered from his illness now, but he
was rather frail and still at times a little confused. A daughter looked
after him in the old cottage which had once rung with the laughter of
many children, and with Ewen’s own; but the old man was alone,
crouched over the fire, with a plaid across his knees when Ewen,
helping himself on the ascent with a staff, arrived at the door.
Half blind though he was, Angus’s hearing was as keen as ever,
and, even with the unfamiliar halt in it, he knew his foster-son’s step.
“Mac ’ic Ailein, is it you? Blessings on your head! You have come
to say farewell to me, who shall never see you again.”
Tremblingly and slowly he arose, and embraced the young man.
“Neil and Lachlan shall go with you, son of my heart, that you take
no harm before you embark on the great water.”
“Neil is dead, foster-father, do you not remember?” asked Ewen
gently. “He gave his life for me. And Lachlan—I fear Lachlan is dead
also.”
“It is true that I do not see them any more,” replied the old man,
with a singular detachment, “for I grow blinder every day; yet I hear
Neil’s pipes very well still, and when the fire burns up I know that
Lachlan has put on a fresh peat for me. Good sons both, but I have
between my hands a son who is dearer, though I did not beget him—
O my tall and beautiful one, glad was the day when you came back
after the slaughter, but gladder this day, for you carry your head out
of reach of your foes!” He passed his hand lingeringly over the bright
locks. “And yet . . . all is not well. I do not know why, but all is not
well. There is grief on the white sand . . . grief and mourning, and a
sound of tears in the wind that blows there.”
“Indeed there is grief,” said Ewen sighing, “grief enough in my
heart at going, at leaving Alba and my father’s house. I was almost
for staying, Angus, did I take to the heather; but the brother of Mac
Dhomhnuill Duibh has been here, and he bids me go. The Chief
himself is going. But we shall return——”
“Some will return,” broke in Angus, sinking his head upon his
breast. “Aye, some will return.” Sitting there, he stared with his
almost sightless eyes into the fire.
Ewen stood looking down at him. “Shall I return?” he asked after
a moment.
“I shall not see you, treasure of my heart . . . But these eyes will
see my own son come back to me, and he too grieving.”
“But I fear that Lachlan is dead, foster-father,” repeated Ewen,
kneeling on one knee beside him. “Is it not his wraith that puts the
peats on the fire for you?”
“It may be,” answered the old man. “It may well be, for when I
speak to him he never answers. Yet one night he stood here in the
flesh, and swore the holy oath on his dirk to be avenged on the man
who betrayed you to the saighdearan dearg. My own two eyes
beheld him, my two ears heard him, and I prayed the Blessed One to
give strength to his arm—for it was then that you were gone from us,
darling of my heart, and fast in prison.”
“But you surely do not mean, Angus,” said his foster-son,
puzzled, “that Lachlan came back here after I was captured? You
mean that you saw his taibhs. For in the flesh he has never returned
to Slochd nan Eun.”
“Yes, for one night he returned,” persisted the old man, “for one
night in the darkness. None saw him but I, who opened to him; and
he would not go near the house of Ardroy, nor let any see him but his
father, because he was sick with grief and shame that he had left
you on Beinn Laoigh to the will of your enemy. Ah, Mac ’ic Ailein, did
I not feel that many things would come upon you because of the man
to whom the heron led you! But that I never saw—that he would
betray you to the saighdearan dearg! May Lachlan soon keep his
oath, and the raven pick out the traitor’s eyes! May his bones never
rest! May his ghost——”
Ewen had sprung up, horrified. “Angus, stop! What are you
saying! That man, the English officer, did not betray me: he saved
me, at great risk to himself. But for him the redcoats would have shot
me like a dog—but for him I should not have escaped from their
hands on the way to Inverlochy. Take back that curse . . . and for
Heaven’s sake tell me that you are mistaken, that Lachlan did not
swear vengeance on him, but on the man who took me prisoner, a
Lowland Scot named Guthrie. That is what you mean, Angus, is it
not?”
But Angus shook his grey head. “My son swore vengeance on
the man who was your guest, the English officer who found you in
the bothy on Beinn Laoigh, and delivered you up, and told the
soldiers who you were. Lachlan found this out from the talk as he
skulked round the Lowlander’s camp in the dark. Vengeance on the
Lowlander he meant to have if he could, but he swore it for certain
against the other, the English officer, because he had broken your
bread. So he took oath on the iron to rest neither day nor night till
that evil deed was repaid to him—he swore it here on the biodag on
which you both saw blood that day by the lochan, and which you
bade him not throw away. I think he meant to hasten back and lie in
wait for the English officer as he returned over the pass of
Corryarrick, and to shoot him with the musket which he had stolen
from one of the redcoats. But whether he ever did it I do not know.”
Bewildered, and with a creeping sense of chill, Ewen had listened
mutely in order that he might, perhaps, contrive to disentangle the
true from the false in this fruit of the old man’s clouded brain. But
with these last words came a gleam of comfort. No, Lachlan had not
succeeded in any such attempt, thank God. And since then—for it
was in May that Windham had returned over the Corryarrick—his
complete disappearance pointed to but one conclusion, that he was
gone where he could never keep his dreadful and deluded vow.
Ewen drew a long breath of relief; yet it was rather terrible to hope
that his foster-brother was dead.
Still, he would take what precaution he could.
“If, when I am gone, Angus,” he said, “Lachlan should return
here, charge him most straightly from me that he abandon this idea
of vengeance; tell him that but for the English officer I should be lying
to-day where poor Neil is lying.—I wonder if anyone gave Neil
burial,” he added under his breath.
But Angus heard. He raised himself. “Lachlan buried him when
he came there after yourself, Eoghain, and found you gone, and was
near driving the dirk into his own heart, as he told me. Yes, he
stayed to bury his brother; and so when he came to the camp of the
redcoats they had taken you to Kilcumein. But all night long he
prowled round the tents, and heard the redcoats talk—he having the
English very well, as you know—and tried to get into the tent of their
commander to kill him while he slept, and could not. So he hastened
to Achnacarry, and found Mac Dhomhnuill Duibh, and besought him
to go with the clan and besiege the fort of Kilcumein and take you
out of it; but the Chief had not enough men. So Lachlan came here
secretly, to tell me that he had not been able to stay the redcoats
from taking you, and that Neil had been happier than he, for he had
died outside the door before they entered to you; and all that was left
for him was to slay the Englishman—and so he vowed. But now, it
seems, the Englishman is not to be slain?”
“A thousand times, no!” cried Ewen, who had listened very
attentively to this recital, which certainly sounded as if it had come
originally from Lachlan’s own lips, and some of which, as he knew
from Archie, was true. “Remember that, if Lachlan should come
here.—But I cannot understand,” he went on, frowning, “how, if
Lachlan overheard so much of the soldiers’ talk, he did not overhear
the truth, and learn how Major Windham ran in and saved me from
being shot. Surely that is the matter which must most have engaged
their tongues, and in that there was no question of delivering me up.”
“I do not know what more my son heard,” said Angus slowly, “but,
when a man hates another, does not his ear seek to hear the evil he
may have done rather than the good?”
“Yes, I suppose he did hate Major Windham,” said Ewen
thoughtfully. “That was the reason then—he wanted a pretext. . . .
Indeed I must thank God that he never got a chance of carrying out
his vow. And, from his long absence, I fear—nay, I am sure—that he
has joined poor Neil. Alas, both my brothers slain through me, and
Neil’s children fatherless!”
“But Angus Og goes with you, is it not, son of my heart, that he
too may put his breast between you and your foes?”
‘That he shall never do’, thought Ewen. “Yes, he goes with me.
Give me your blessing, foster-father; and when I come again, even if
your eyes do not see me, shall your hands not touch me, as they do
now?” And he guided the old hands to his shoulders as he knelt
there.
“No, I shall not touch you, treasure of my heart,” said Angus,
while his fingers roved over him. “And I cannot see whether you will
ever come back again, nor even whether you will sail over the great
water away from your foes. All is dark . . . and the wind that comes
off the sea is full of sorrow.” He put his hands on Ewen’s head. “But I
bless you, my son, with all the blessings of Bridget and Michael; the
charm Mary put round her Son, and Bridget put in her banners, and
Michael put in his shield . . . edge will not cleave thee, sea will not
drown thee. . . .” He had slid into reciting scraps of a sian or
protective charm, but he did not go through to the end; his hands fell
on to his knees again, and he leant back and closed his eyes.
Ewen bent forward and threw some peats on to the fire. “Tell me
one thing, foster-father,” he said, looking at him again. “Even if I
never leave the shores of Moidart, but am slain there, or am
drowned in the sea, which is perhaps the meaning of the wind that
you hear moaning, tell me, in the days to come shall a stranger or a
son of mine rule here at Ardroy?”
Angus opened his eyes; but he was so long silent that Ewen’s
hands began to clench themselves harder and harder. Yet at last the
old man spoke.
“I have seen a child running by the brink of Loch na h-Iolaire, and
his name is your name.”
Ewen drew a long breath and rose, and, his foster-father rising
too with his assistance, he kissed him on both cheeks.
“Whatever you have need of, Angus, ask of Miss Cameron as
you would of me.”
“You are taking away from me the only thing of which I have
need,” said the old man sadly. “Nevertheless, it must be. Blessings,
blessings go with you, and carry you safely away from the white
sands to her who waits for you . . . and may my blessings draw you
back again, even though I do not greet you at your returning.”
When Ewen came slowly down the path again he found himself
thinking of how he had descended it last August behind Keith
Windham, nearly a year ago. The story of Lachlan’s vow had
perturbed him, but now he saw it in a far less menacing light. Either
his foster-brother’s unquiet spirit was by this time at rest, or the
whole thing was a dream of that troubled imagination of the old
seer’s, where the distinction between the living and the dead was so
tenuous.
Soon he forgot Keith Windham, Angus and everyone. Loch na h-
Iolaire lay before him under the sunset, a sunset so tranquil and so
smiling that in its sleepy brightness, which mirrored all the mountains
round, the loch seemed to hold the very heart of content. Ewen had
the sensation that his heart, too, was drowned there. And by his own
will he was saying farewell to loch and mountain, island and red
crag. He remembered how Alison had said that he would be hard put
to it to choose between her and them. Was she right?
There was a place where for a little there was no bank, but
marshy ground, and where the water came brimming into the reeds
and grasses, setting them faintly swaying. He went to it, and,
stooping with difficulty, dipped a cupped hand into the water and
raised it to his lips. Perhaps that sacramental draught would give him
to see this scene as bright and sharp in dreams, over there in the
land of exile whither, like his father, like all who had not counted the
cost, he was going.
As he drank there was a loud croak over his head, and, looking
up, he saw a heron winging its slow, strong way over the loch
towards the sunset. It might almost have been the same heron which
he and Alison had watched that evening last summer, when it had
seemed to arrive from the western coast like a herald from him who
had landed there. Now it was going towards the coast once more, as
he, the outlaw, was going, and as his Chief and his fugitive Prince
would soon be going. In a little year, between two flights of a heron
seen over Loch na h-Iolaire, the whole adventure of ruin had been
begun and consummated.
Well, if one’s life remained to one it was in order to come back
some day and renew the struggle. Ewen took off his bonnet. “God
save King James!” he said firmly, and turned away from the mirrored
mountains to take the same path as the heron.
CHAPTER V
This sea-fog, Keith Windham decided, was worse than the inland
mist; thicker, more woolly, more capricious. Yesterday, for instance,
one had wakened to it, and all day it had cloaked sea and shore and
the wild, tumbled mountains of the ‘Rough Bounds’. Yet towards
evening it had suddenly lifted, and the night had been clear and
moonlit. But this morning the white veil was down again, and only
now, some hours after sunset, was it clearing away.
And this was all the more vexatious because in the silver
clearness of last night he had distinctly made out a strange vessel—
a Frenchman, he was sure—anchored somewhere off the isle of
Rum. But in the day, thanks to that muffling fog, who knew whether
she was still off the coast or no! Yet in a few minutes more, when the
moon came up from behind the mountains, he hoped to be able to
see as far as her anchorage; meanwhile, followed by his orderly, he
rode slowly along the flat shore in the direction of Morar.[1]
[1]Pronounced Mórar.
No one could accuse Major Keith Windham of neglecting Lord
Albemarle’s instructions; if anything, he went beyond them in his
ceaseless vigilance. Quartered himself at Arisaig, he thence
patrolled the coast in both directions, from Loch nan Uamh, the
Adventurer’s original landing-place, to Morar of the white sands on
the other, and had his grumbling men out in all weathers, at all hours
of the day and night, and for any kind of false alarm. But he spared
himself still less than them, taking little sleep and covering miles
every day, often on foot. If fatigue, like virtue, were its own reward,
then he had that recompense. And so far it was his only one.
But at least Keith felt tolerably certain that no fugitives had yet
made their escape from his strip of coast, no fugitives of any kind.
For, apart from using every endeavour to secure the person of the
Pretender’s son, he had been instructed to prevent all
communication with French vessels, of whom one or two might
always be hovering off the coast. These nights, therefore, that this
ghostly ship was visible, it naturally behoved him to be