et aA HQC PHAN; SINH HQC DAI CUONG Hip Va tr 0th MIE: eee ee 8G be el Lop: XNI ; : Ngay thi: ngay 05 thing OF nam 2018 Thar gtan lam bal: 30 phiit (Thi sinh phai ndp Iyi dé thisau khi thi xong) Chit §: Clu ding dueye chon bing cdcle dieng viet bi hogic viet may 10 den vao vong tron c6 RS te ma cho clu ding. Vi di ®) HOQDMSectyn ctu B) nr mud sia cs OFOD Oreo ‘elu B bing ctu D) Thi sinh hay chon I edu tra lai ding nhat: Clu f: Gidt han vé kich duede 63 da ciia té bao phy thupe vao yéu tb ndo sau day? y ASO Jung bao quan. B. Ti lé dign tich/thé tich. ee jugng DNA trong nh D, S6 Luong té bao bén canh. —p ) day cha ming sinh cl 2: Clr re nde smu dy iong hm thdy trong té bao nhin so? . Ootra B. Mang sinh oh C. Tithe. —_D. Ribasome.. E, RNA, “iu 3: Té bao cé chéta ti thé, ribosome, lurdi npi chat tron, edi noi chdt hat va cde bao quan khdc. Cho Swi a i 18 bio dé khong thuegc logi nao sau day? or A. TE bio ey thong. baochéuchéu. C. Té bao nim men. D. TE bio vi es E. Bat cir té bao nao ké trén, Clu 4: Think phan "tae quan nao sau day cd trong 12 bao nhéin so? ‘A. B6 may Golgi. 34 ithe C.Caenhincon. DiEnzyme. — E.Tét cd cde dip din trén déu dane (Caw 5: Chite nit iy fittin com 1a gi? @ Chita vat chi dlitnuyén ila té bao, B. Bign d6i cdc chit chuyén tir mang lu6i noi chit, Té chite slip xép cc sgi cia thoi phan bio, D. Cung cdp nguyén ligu dé tong hyp ribosome. E. Tt c& cfc dép din trén déu sai. Spb: 6: Khi té bio gan pies Map dicge xit li vii chit dpc, bude dau tién trong qué trink bat tét chide dpc trong bao quan nao’ ate ni chat tron. 2 BO miy Golgi. C.Ti thé. —_D. Ludingi chat hat. La cb ot ated g6ctit di va ed chiée nang gi? TA Titnomhe B. 9 midy Gol va lui ndi chit havitidu hod cdc blo quan gid. Trung tim, es vi panes tr ATP, D. Vi khutin eng sinh/di truyén ngoai nhan, han con/hd hap higu ay, ue ey ‘hotin think civ saus thé va Luc Lop ging nlatt @ CHD wwsrrrrmorvn VO Kleéc nhau & cltd wu ‘Deu cd, ake e6 chic ning quang he hgp con ti thé thi Kang | . C6 ming trong a ting cirimg dién tich/uc gp c6 6 thure vat con ti thé thi khdng. | Ce Chek Ghee oMuele wt vee ts Seu thentiiee E. Lysosome: D. Cé chite nding chuyén hej oles firong/luc lap chi thay & té bao nhin thye cdn ti thé thi cd ca & 18 bio be ee vad bao nhiin so. feb ohira DNA. A ci ta er ene RAL Be te there Bo ? Ae ‘sit dung. bio se qua Di xuat stn phim nur insulin hode thiroxin. GMotté bao bit vi oe hhinh thanh chan gia bao quanh ly vi khuin va gi nd vao béng thye SE rp ete oh WE Ck chschsbon tx ceva chu n vao té bio nhé thyc baw.Shi c6. cde chat gin ngogi bio dae tung mdi di vio tébaonhdrthye bao. ‘Suut Khi vao té bao, cde bing nhip bao s8 di chuyén va hoa vao bo may Golgi. Cau, 10: TE bao nao cita ngud lt cé kha nding phan chia? C. Té bao ung thir PTé bio than kink, B. Té bao da. 'D. Té bao phoi. E. Té bao lot think rapt non. “yf Ll: Nhiém sde tit 06 de diém gi sau diy? F Chi théy trong NST sai léch, —_-B. Gn voi nhau bei trung tir €. C6 chita RNA. cling mot NST. } La nhimg ban sao gidng hét nhau cts. nhumg co trong NST gidi tinh X. E. Khong tn tgi trong NST gid tinh Y, we 12: Khi cho moi té bao 6 pha S kée hop voi ne té-bio mot té bio @ pha GI thi diéu gh xix ra? te bdo GI. ai ban DNA xéy ra trong nhén té bao S s® ding Iai. Hat nbiin két hop ea sir phn chia saul 46 ding Iai D. Cée NST ella nhén GI de igi va chudn bj cho nguyén phan. . TE bdo G1 s@ phan chia tic thi, (Cin 13: Tromg bl trang gian, vee chdt a traydn ca mt ié bao nan thyre didn hink dang no? Phin. tan trong nbn dudi dang sgi nhiém sic dai Phan tn trong té bao chit dudi dang sgi nhiém sic dai. T LANST c0 die throng quan sat dirge didi kinh hién vi quang hoe, D. Giin véi ede soi cita thoi phéin bao, £. Buge van chuyén qua 18 mang nhan. Clue 14: Cae nhiém sée tie hinh thanth trong giai doan nto sau day? ta E, Dau gidim phiin 6 Sir tng hop DNA bat diiu tire thi trong nhain ‘A. Pha Gl. PhaG2, C.PhaS. —_D. Dau nguyén phan . : (Cau. 15: Trong ki evbi cia nguyén phan, thoi phan bao tan ra va ‘ehdt nhtém sic gidn xodn. Hign wgng ‘6i hin urgng xay ra trong ki nao ciia pha phan bao? Kida B.Kitang gan, C.Kigita. D. Pha S. ERI sau iz Su hign no xdy ra trong ki dau caa nguyen phan? 9 Bat dtu ink thanh thoi phin bao. B. Tng hop ming nhiamdi. 5 Li i « Ditn hing cia NST trén mot mat phing. D. Phan chia té big cl E. Phan chia trang tidt, aa 12: Dip dn nito sau day ta,sai? Ki déu : NST xofin chat hon. B, Ki gita: NST xép thinh hing trén mat phing xich dao. IKI gitta : mang nhan bién mat D. Ki sau : NST di che éhal Extra n a a Hoke gitar ctey tn oth Sct Gu tS. Cie gia ‘A.Chutrinhté bio, —B. Thu tinh, iim phan. _D. Nguyén phan. Sinh san v6 tinh. Cau 19: Glim phin I sin sinh bao nhidu té bio va céc t€ bio 06 dec diém g ‘A. Hai té bao dan boi kép. B, Ban té bao don b9i. C, Hai t€ bio luting bi. Dd. as E, Hai té bao gidng het nhau. ee pi chika NST chsh ‘hat nhiém sac tit chj em o giai dogn nio sau dy? i gitta HI va phin chia té bio chat. B, Kicudi I va phiin chia 1& bao ch. (Ge i chit. 1, Kicudi Il va phan chia t€ bao chat‘rong co thé sing cite nguyén 16 phd bién ta C,H, O,N, Ca, P, B.C,H,N, Ca, K, 8. C.C,H, 0, Ca, K, P. ', C, Cl, Mg, S. ie H,O,K,P,S, - i Thugt ng “phan.dai” diege dp dung cho di Ni tegng mao sau day? a B.Thye v@t, Cesinn vat nhdn se. D, Nguyén phan, E. Hoa hoe nhiin té bio. » Clu 24: Nhin té bio cé chite nang: 7 A. Dieu khién moi host dong sing cia té bio. & C. Tong hyp protein. 1D. A va B du ding. Ciw IS: Sie kién nto xdy ra trong kt sau ctia nguyén phan? A.Thoi,phén bao xudt hig Cae nhigm sic tir giGng hét nhau di chuyén vé hai eye. ©. Trung tir phan chia, D. Trung tir é hai phia eve 46% lap. Tit ci ede dip an tren du ding. Ciu26: Dél véi hpi ching Dawn, ugwii bfnh cé thém mot NST sé 21. Vay hoi chitng Down thupe dang nao va cé nguyén nhan nao sau diy? A.Chuyén dogn NST/ gen nhay chen vao gitta NST 21, \¢ da bOi/giam phan xay ra chdng kém phan chia té bao chit. ©THE lech béi/syr khong phan li cia NST 6 21 trong gidm phan. D.Sai hong eta qui trinh tdi bin/hém mot NST 21 trong qué trinh tdi bin & pha S t E. Tat ea cde dap fin tran du sai. Cit 22:78 bio niin so degre phan bit véi td bao nhén chudn b6i du higu: A. Cé hay khéng c6 ribosome. B. C6 hay khong 6 thank té bao. ‘Mang théng tin di truyén. /B vi C du ding. (Oo hay khong 66 csc bdo quan duge bao bg boi lép ming, : = D-Cé hay khong 06 long wa roi, E. Cé hay khéng cé cdu trie ADN. (Ginza ite diém che igo ndo sau day cé ci 6 RNA va DNA? ’ =Chita duréng CsHyoOs B,Mech don ty cudn xodn, prec dem, D.Mach kép. aT E,Chma ducemg per iclogi RNA la: 4-8 ~ B D. A vAC ding. EA VAB ding, fogi RNA la: D.A va B dang. EA VAC ding, val (rd: A. Digu hoi than nhigt sinh vge va moi trang. B. Dung moi hoa tan, nguyén ligu cho céc phan img trao dai chit. > Teo lye hit mao din, giép vén chuyén nurdc trong co thé thy wat, hicd A va B. E.C&A, Bvac, it 32: Protein cé dite tinh: A.Bén ving nho co nhieu lign két hydro. B.Da dang, C.On dinh tuomg ai. D.A VAB ding. VaB ding, Gin 33:Chu trite cia phan ti protein e6 thé bj bién tinh bai ‘A. Lin két phiin oye ca cde phiin tir nurée. (Bie as. C. Suc6 mat cia khi O, . Sy cd mat eta khf CO. E. Céc phuong ain trén déu sai, Cau 34: You tb guy dink tinh da dong cia protetn ta: ‘én két peptid. Bho R cia cic axit amin, Chm aed cc re C.Nh6m amin cia cde axit amin. tein, Etupden gene trpi tren NST gine may, Kha nang tng mide 49 bid Che 35: Thice vBt le t9@ dicing died dang polisacearide mio? A. te is Tinh bet. CVn chuyén. D.Axit béo. E.Glyeogen. ‘op vid nhaw my Sac trie: khBing chive axit.npsctele 1: theo dink luge A\Nhfin té bio. = B.Ti thé. ic lyp. _D.Ribosome. (Bi ni chat trom, 0 durdi day: Cay 37: Hay chon clip dép dn dit “bdo quan - chite nBiag cha bio-quan’’. : E. 2pq \6ng bio trung tim — tidu hda ndi bao. (Si thé -hé hdp té bao. ibosome - tng hop lipid, ‘D.Nhiin = quang hyp. E.Lysosome - vn ding. Chu 38; Chu trite nto sau day dim nda chite ning vin chiydn cd chon toc cde chit vito ra tb bio? A-Ming nhin. — B.Nbiin, ‘Ming sinh chat, DiLysosome E89 may Golgi. Cau 39: MOI ngicdt b] mat mde ning, dé bd sung chés ting cho co thé, nguit ta eruyén made cde tree He) vido migch ngicel bink. Bib nay cd thé sé: A. Khdng 6 higu qué bat igi vi nude Ing 06 vi tring. - B. Haw qua nang ne 06 thé gay chét vi cé qcia nhidu nude dé tim bom di, Hau qua nding né gay fe vicdc té bio hdng clu c6 xu hugng bj ve. D. Hau qué nding né gay chét vi cdc td bao héng cllu.cd xu hudmg co lai. FE Khdng ed hau qua nding né vi co thé nhanh chéng thai nde thira.. ; Lact nol chdt trom king cd chite ndng mio sau diy? s ‘A, Tong tigp lipid. 8B, Didu hoa su gidi phong durémg tir yan ra mau. » Gia age 16, 1D. Tong hep protein dé tiét ra ngoai té bao. NYA 2017-20)8 = y tet can, HET.DE: B PHAN THI MON: DI TRUYEN Y HOC Fo waitin sinh viém: . ee SB bo: deanh irae 2: ANYHL Naga ti: ngasy 05 thang O1 rim 2018 Sb eta: 40 Thai ian tim bak: 35 pit Thi sinh phat ndp igi 48 saw Kh) thi xong (Chil §: Cat dig ue cl bang cifch dang viet BF bor den vio von trdn &b Ai ue mn cho ct ang. Hd: DO OQOE® (hon ctu By nda mda sia dea BIO OE) ‘Hay chon cau ding mhdt: |. Hign tregng hike deg “ngeedi sing Ip" la hién tweens A, Mot nhom ca thé tach ra khoi quiin thé lon hom tao nén quiin thé méi mang vn gene dic trumg ctia quiln thé gbe B. Sy thay d6i ngiu nhien tin 56 cha céc allele trong mét quin thé nho , Hign tugng nhitp cur cia mot sé lirgng Kin c& thé vio md quin thé nhé D. Phit tin chim chap cha gene qua bién gidi lam thay déi din tin s6 cua cée allele cia quén thé ‘thom cA thé tich ra bhO# quiin thé lin hon sau 46 tin 36 cia cdc allele trong quan thé md ‘ehile bigt so v6i quan thé ede Vhting ngirdt mile bénk hemophilia. A hoje hemophilia B thurdng cd kiéu hink gin gibng nhau. Tuy A ‘et qua cata sue dpt bién 6 cdc gene khuic nhau trén nhiém sic thé X. Dé ld wda A.Tinh bidu hign da dang @rrinis aa rigu E. Tinh dj nguyén v8 allele B. Tinh dj nguyen vé locus D, Tinh thm giim 43. Trong phitn tich nhiém sdc thé bing kj thudt lap karyotype tie té bdo Iymplro miu ngogi vi, chdt PHA Eliokensagplatinin) cl atin) no seu diy? Phd bily. Ng cau dé tyo ditu kign thudn loi cho burde nbd titu bin, Kich thich 1é bao lympho T chuyén think dang nguyén bao lympho co kh ning phan bio, Pha hy thoi phiin bio 2 os ag pn Uh 0 ky wit ‘D. Ue ché sir phsttrién ci vi khuin va nim trong dng nudi ely, E, Cb dink hinh thai bio lympho sau khi di durge sc nhusge trong. Intron cé dic diém rio sau day: \. int nucleotide tal hod cdc acid amin yin xen i phién mf va tham gia vio qua trinh dich ma vtrong phn tr mRNA tnsimg thinh din Ong mang chuyén dogn ucong hd dén co siy i xin de vin di truyén, nhang nhon at tran ita bénls nian nay la ditng: ain dupe tu vin kiém tra igi karyotype vi ed mang chuyén dogn twrong, hd nhumg bam than Iai khong 66 sinh, cfm phit trién tin thln bode bénh i dc tinh ¥ . . you 166 6) nim sie thé binh thirdng thi s® khdng ed blt thutmg thal sin xy ra (vt du sly | it bam sinh vayhoge chim phat trién tam thiin...). Bee a: nnhiém sfc thé binh thutmg thi vin khong bao gid thy thar duge ne6 thé mang thai hg hn ce chin 6 lt hung nbn sic oe pe pee tah com bjdjrat bam sinh virhoge chim pha trién im rho sinh con ‘Sic thé ndo saw diy dhege siz dung thedvg quy dé phiin tich bat theong it bin sink véchoge chém phds trién sam than: ee exon C6 mang hop TATA AYE 2017-2018 Bd 8 1/648 M@t buh di truyén gene lin trén NST tieing cb tn sd allele apt bién q = 0,2. Té 12 nguedt mite bfntt nay trong mt quar thé can bing di truyda wée tink ti bao nhiéu? At B. 90% 46 D.95% E, 96% 49. Trarimg hgp nao sau day cé inpt dim giy tren cdc nhiém sdc thd tham gia vao kid bat thiedng edu trie tang sng: . Milt dogn git. C.Chen doan. E. Dio dogn ngoal thm, ‘Mit dogn du mit, 1, Dio doan quan tam. = 50, Ya td nado dirbi day néuxay ra.sé khong tim inh Icing dén tin s6 ctia cdc allele trong quin thé ) Higa nang ngdiu phdi, D. Sy phiéu byt di truyén. B, Tac dong cia sy di dain, E, Dong chay cita gene: _ __ ©:ite ing ca chon lgc, dot bi. : Sh. KP thugt ndo sau day duege siz deing dé chiin dodn mhanh cdc bit dhucdng sb lugng NST 21, 18 wi 13? ALK thudt FISH: B, KG thst QF-PCR f thudt Ip karyotype trén miu té bio dich di IK thudt Ip karyotype trén miu té bao gai nhaw Chu A VAB doing FY Trong ete bg sau day, bénh do KHONG duege sing Joc trén miu méu git chan cia tee? SA Say aid tink ys lt sinh re uc tpkniiong uasoliieb ee sinh E.A viding ‘CDI ft tm bam sinh 53. Trong quin thé 9 1é nhém bénk di truyén nao phd biéaghdar: A. Do doe bién dan gene Di truyén da yeu 16 B. Do dot bidn 36 lugng NST E. Do dgtbién cfu tric NST CDo d0t bién gene ngoai nhin $4. Net nghiém chin doin treeie sinh od Age diém nito sau day? A.Ré tidn, dB thye hign viiod 46 tin fy cao. 'B. KhGng gly anh hutng dén sire khoe cia thai phy va thai nhi. (G. Laxxét nghiem cho phép xac dinh chinh xée tinh trang mide bénh ota thai nhi- Layer nghidey thing quy, thy hign cho tt cd cbc thai phy, ‘xétnphitm che phép xc dinh kh nang me bgnh eda thal nh. 5S. Trong kB thuge phan thch nhtém sic thé, chdr trypsin dhege sit dung dé A. Lim ming té bio trirnén-ving chic hon. + B. Ph yo ming nan té bio lympho. [Bio v8 nhif sie thé khong} din ty.» "Tie dng én protein shim igo bang G trén-nhidm sic thé. 'E: Shc nlupe trang dé ting thé tich t& bio lympho.» 56. Sia GEN cas nh gdm cic thank phiin diege sip xép theo thir tw ndo saw day: 2 Wing S” khong dich ma aa 4h 3. Mil Guanine bin 48; hod hoc hig nao ? atig Ak Agi ch D.Bénh Huntington Sip ps Se ia te sins Ba selina yy) Soa) Bbchnhbe bb beprg mb sh hE rong bt sgh dng 59. Bén ‘bio sit ta: AB B46 co 92, E. 138 ‘xnre 2017-2088 Bh B24 ah ido sau dy 1d gu quad cila dpt bién gene Idi mat chice nang protein: ea70. MOrcap vo-ching déumdc phaimot bénh di trupén gene wpilien két NST tuedng cd tinh théim 80%. Hay cho biét xie xuit cap vg chong nay sinh be KHONG ee bénh la bao nhiéu? Biét ring cé hai sy chang déu mang kiéw gene dj hgp tir. et 2 Gare €.40% 4 fo §, 80% 9%, D.60% A 40 a 71. Hay sip xép cde nguyén nhdn cia tam boi sae day theo duit te tie thuing gap. nhlit dén ft gdp nhit. a) Mot trimg cing tha tinh véi hal tinh tring (dispermy): BY Ne tah ade hd ie hing ty tinh wi md ih fag) ©) M6t ting hod m6 tinh tring ltms: bi thy tink v6 giao te binh thudng. A)a,b,¢ Baen | ‘C-cba D.b,c.a Ebae S a mg genome nguedt, logi DNA nao la chi yéur INA de bin D.DNA mahod cho cic #RNA DNA itp E, DNA vétinh C. DNA mach yong 73. Trong ede togi dor biéy.thay thé nucleotide, lagi nio thiring gap nhat: Gt bién im lang D, Dot bién j tri edt ni Opus sai nghia E. Dot bién ving diéu hda .C. Bot bién v8 right ae (ue ‘aguedi din ong mike béah hemophitia A (bénh di truydn gene lan. 9) két hon vbh mbt SS phy nit li ngudi tink mang gene cia bénh ndy. Kha ning clip ve ching nay sinh con ede 1d neieOy 9 lihh mang gene banka bao nhldu? BS trons A.0% )25% C.18 D.50% E. 100% Cy he (6 tii ndo saw day ding voi bdt thurémg nhiém sac thé kiéu trisomy (tam phiémy) chi cc catp nhiém sac thé trong bo nhiém sic thé déu c6 ba nhiém sic thE ‘$6 nhilfm sie thé trong nhin mbi té bao tang gp ba lin. 1G mOt cp nhiém sic thé gdm ba chiéc, cic cp cOn Iai binh thutmg. ~~ ‘D, Bir thurtmg lien quan dn nhiéen sic thé sé 3. -E, C6 ba cgp nhiém sic thé bj bar thutmg. 76, Dpt bién tai codon 6 cia gene fi globin lam codon GAG thanh codon GTG la nguyén nhan gay ra ier do sau déy: xo D.Bénh tang cholesterol cé tinh gin dish Gaghndog che tinh idm E. Boh Hemophilia A C. Bénh a thalassemia 77. Benh, at ndo dieét day khdng cd nguyén uhan di truyén da yeu db: ATi ke or moi him D. Cae dj at tim bm sinh Hi chimg Turmer E. Bénh tam thin phiin ligt C-Che ‘gt cia Ong thin kinh ; 78. Mt bé gdi 10 tél duge chan doin mic ae ching Marfan, mot bénh di tri thirding, Khao sit pha h@ etia ob bé cho thi yin gene tri tron NST hong 66 tién sit gia dink vé hoi chieng nay. KI y ee eine ig C6 tien sit gia dink ve atne nay. Kha nang ‘Bi i ong ching Nort @o« bién mi B.Tinh thm tim Kh beh sim va gia tang mie dg bide hign & CTinh da hid hehe sau erpitese oes 79, Bot bidn dich kKhung od dic diém: ALA d5t bidn them 3 nucleotide BLA dot bidn mit 3 nucleotide C, La dg big lim mt codon kés thu tri thinh codon cé: nghia Liam thay 48i m@t acid amin trong chudi polypeptide Lim thay 48i toan b} trinh ty chudi polypeptide ti vj tri dot bién 80. “Gia sit god p Id tin 58 cha allele A, 4 td tin 36 cha allele a vi cite allele két hop wii nhau mor ech whién trong quiin thé. Cdc allele nim trén nhiém sic thé thicdng. Theo dinh luge Hardy Weinberg tin s6 ciia cde kiéu gene AA, Aa, aa duege thd hifn qua cOng thite ndo ducdi iy Apr amtq Bu? + 2pq Cope g? CBP 204+ 4 EB. cam