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Foreword
I
n the past two decades, informatics as a terminology has been widely dis­sem­
i­nated. Within the health sciences context, medical informatics and bioinfor-
matics have played an important role in advancing the health services domain
as well as in ­discovering biological associations and informing new treatment
­discoveries. ­Population health informatics is a newer emerging science that prom-
ises to ­influence global health dynamics in a unique and significant way. This
text ­elucidates the ­underpinnings of this terminology, and explains its unique
­parameters and singularly effective applications both from descriptive and inter-
ventional dimensions. The readership of this text will gain new insights and will
be able to use newly acquired knowledge in both theoretical and applied context.
Knowledge gained through this text will inform large data users, health scientists
and researchers, health ­administrators, and policymakers, as well as economists and
modelers. Many of the challenges associated with population health informatics
relate to difficulties in assembling data, combining data sources, identifying inno-
vative approaches to data analysis, and finally, extracting the most relevant and per-
tinent information toward predicting and resolving emergent and prevalent health
problems. Many of these challenges are addressed and demystified in this text, in a
way that is accessible to students, researchers, and practitioners in the field.

Ayman El-Mohandes, MD, MBBCh, MPH


Dean, The City University of New York
Graduate School of Public Health and Health Policy
New York, New York

vii
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Acknowledgments
T
his book would not have been possible without the wholehearted support
and ­participation of several individuals. First, we would like to thank the
Dean of the CUNY Graduate School of Public Health and Health Policy,
Dr. Ayman El-Mohandes, for his motivation and invaluable support and commit-
ment to helping us bring this book to its completion.
We would also like to thank Chioma Amadi, Research Associate and a doc-
toral student of Epidemiology of CUNY Graduate School of Public Health and
Health Policy, for her valuable assistance in writing a chapter and reviewing the
content of the book. Further, we would like to thank Princy Bhardwaj, MPH,
Environmental and Occupational Health Sciences, and Rinzin Wangmo, MPH,
Health Policy and Management, who provided assistance in reviewing the references­
included in the book and gave us valuable insight about their level of understanding
of the content of the book.
In addition, we acknowledge the extraordinary competence of our Executive
Editor, Michael Brown, and Associate Editor, Danielle Bessette, at Jones & ­Bartlett
Learning, who guided us through the publication stages and provided valuable
advice. Our Senior Production Editor, Amanda C ­ lerkin, and her colleagues adeptly
dealt with a number of challenges to make this book look better than it would have
otherwise.
Finally, we would also like to acknowledge the chapter contributors who
played a very significant role in making this book possible. Despite their hectic
work ­commitments, they shared their expertise by writing the chapters, responding
to inquiries, and modifying the draft chapters as suggested. We are very thankful
to these esteemed contributors who come from various areas of population health
­informatics.

viii
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Contributors
Chioma Amadi, MPH Hadi Kharrazi, MD, PhD
Research Associate, Doctoral Student Research Director
in Epidemiology Center for Population Health IT
CUNY Graduate School of Public Johns Hopkins Bloomberg School of
Health and Health Policy Public Health
New York, New York Baltimore, Maryland
Luk Arbuckle, BSc, MSc Harold P. Lehmann, MD, PhD
Research Manager Associate Professor
Children’s Hospital of Eastern Johns Hopkins Bloomberg School of
Ontario Research Institute Public Health
Ottawa, Ontario, Canada Baltimore, Maryland
Ann Cavoukian, PhD Edward Mensah, PhD
Executive Director Associate Professor
Privacy and Big Data Institute, Health Policy and Administration,
Ryerson University School of Public Health
Toronto, Ontario, Canada University of Illinois at Chicago
Chicago, Illinois
Michelle Chibba, MA
Strategic Privacy/Policy Advisor Katharine H. McVeigh, PhD, MPH
Privacy and Big Data Institute, Director of Research
Ryerson University Division of Family and Child Health,
Toronto, Ontario, Canada NYC Department of Health and
Mental Hygiene
Brian E. Dixon, PhD, MPA, FIMMS
Queens, New York
Associate Professor
Richard M. Fairbanks School of Saurabh Rahurkar, BDS, DrPH
Public Health Researcher Postdoctoral Public Health Informatics
Center for Biomedical Informatics, Fellow
Regenstrief Institute Center for Biomedical Informatics,
Indianapolis, Indiana Regenstrief Institute
Indianapolis, Indiana
Khaled El Emam, PhD
Professor
Department of Pediatrics, Faculty of
Medicine, University of Ottawa
Ottawa, Ontario, Canada

ix
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About the Editors


Ashish Joshi, PhD, MBBS, MPH
Associate Dean and Associate Professor
CUNY Graduate School of Public Health and Health Policy and the CUNY Institute
for Implementation Science in Population Health
Ashish Joshi is an Associate Dean of the CUNY Graduate School of Public Health
and Health Policy and an Associate Professor at CUNY Institute for Implemen-
tation Science in Population Health. Dr. Joshi’s combined training in medicine,
public health, and informatics provides a unique combination to utilize innovative
­technology-enabled interventions at the intersection of clinical care and popula-
tion health. Dr. Joshi’s journey has been that of an academician, applied researcher,
­administrator, innovator, and entrepreneur to implement sustainable, multi-­sector,
accessible, affordable, reimbursable, and tailored (SMAART) t­ echnology solutions
to address the population health challenges of the 21st century. His research ­interest
focuses on the design, development, implementation, and evaluation of contex-
tually relevant informatics interventions to enhance population health outcomes.
Dr. Joshi utilizes the principles of social cognitive theory, human-­centered design,
and ­information processing theory to develop culturally relevant health tech-
nology solutions that can be adapted to different settings, audiences, and health
conditions. Dr. Joshi has done several population health informatics ­projects in
various countries including the United States, Nigeria, India, Brazil, and Haiti. His
research ­related to mobile and Internet-enabled interventions, population-based
surveillance, consumer health informatics, and health dashboards has been widely
funded by several ­national and international agencies.
Lorna Thorpe, PhD, MPH
Professor and Director of Epidemiology
NYU School of Medicine, Department of Population Health
Lorna Thorpe is Professor of Epidemiology and Director of the Epidemiology
­Division at the NYU School of Medicine in the Department of Population Health.
Her current research focuses on improving modern forms of public health surveil-
lance, as well as the intersection between epidemiology and policy, mostly with re-
spect to chronic disease prevention and management. Dr. Thorpe is on the Board
of Directors for the American College of Epidemiology, has served on Institute of
Medicine committees, and has been an advisor to the Centers for Disease Control
and Prevention (CDC) on population health surveillance issues. Prior to joining
academia, Dr. Thorpe spent 8 years at the New York City Department of Health
and Mental Hygiene, serving as Deputy Commissioner of Epidemiology for much
of that time. Dr. Thorpe began her applied research career as a CDC ­Epidemic
Intelligence Service Officer in international tuberculosis control. Dr. Thorpe

x
About the Editors xi

c­ ompleted her PhD in epidemiology at the University of Illinois at Chicago, her


MPH at University of Michigan, and her BA at Johns Hopkins University. She has
lived and worked in Asia (China, Indonesia) and published widely on both chronic
and infectious disease topics.
Levi Waldron, PhD, MSS
Assistant Professor
CUNY Graduate School of Public Health and Health Policy and the CUNY Institute
for Implementation Science in Population Health
Levi Waldron completed his education at the University of British Columbia (BSc),
University of Waterloo (MSS), and University of Toronto (PhD). After doing post-
docs at the Ontario Cancer Institute and Harvard School of Public Health, he
took a faculty position in biostatistics at CUNY. He is a technical advisor to the
­Bioconductor open-source project for computational biology, and was a Fulbright
scholar to Italy where he taught applied statistics for high-throughput biology. He
continues to pursue interests in high-dimensional data analysis, particularly the
development of databases and methods for integrating genomics data into cancer
and microbiome research.
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Introduction
T
he rapid growth in digital data due to the increased usage of mobile phones
and wearable sensors has created an urgent need to develop new, innovative
tools and technologies that can make data meaningful. Population health
­informatics is an emerging field that aims to utilize technology to put into practice
evidence-based solutions to improve population health outcomes across diverse set-
tings. The goal of this book is to present a practical, step-by-step approach on how
to implement evidence-based, data-driven informatics solutions to enhance popu-
lation health. We aim to engage students and professionals across various disciplines
who are interested in using technology as a medium to reduce health disparities
and improve healthcare access and delivery in diverse settings.
The book is broadly divided into four parts:
Part 1: Overview of Population Health Informatics
Part 2: Setting the Stage for Population Health Informatics
Part 3: Specialized Population Health Informatics Applications
Part 4: Other Population Health Informatics Topical Areas
Part 1 begins by describing the need for population health informatics
(­ Chapter 1) and then discusses the workforce’s needs, competencies, and the various
training programs (Chapter 2). Part 2 discusses differences among data, information,
and knowledge (Chapter 3); health information exchange and related interopera-
bility (Chapter 4); informatics-enabled population health surveillance (Chapter 5);
statistical issues (Chapter 6); and opportunities and challenges related to big data
due to the rapid increase in data volume, velocity, and variety (Chapter 7). Chapter 7
also examines the role of cloud computing and population health visual analytics
to facilitate population health data storage, data analysis, and data visualization in
a meaningful format. Part 3 describes the specialized population health informat-
ics applications such as design, development, and system evaluation (Chapter 8);
electronic health records and telehealth applications (Chapter 9); personal health
records (Chapter 10); and the opportunities, challenges, and applications related to
mobile health interventions (Chapter 11). Lastly, Part 4 discusses other key popu-
lation health informatics topics related to the economic value of informatics appli-
cations in population health (Chapter 12); issues related to privacy, confidentiality,
security, and ethics (Chapter 13); and the role of innovations and sustainability in
population health technologies (Chapter 14).

xii
Introduction xiii

We hope that the information and resources provided in this textbook help
readers to better understand the utilization of information and communication
technology–enabled interventions and innovations in the United States and beyond.
The book fulfills a key component of the new Association of Schools and Programs
of Public Health recommendations for “Critical Components for the Core of a 21st
Century MPH Degree.” The book also equips a new generation of the workforce
with the expertise necessary to make data meaningful and to design, develop, and
evaluate accessible and affordable technology-enabled solutions to effectively
address the population health challenges of the 21st century.

Ashish Joshi, PhD, MBBS, MPH


Lorna Thorpe, PhD, MPH
Levi Waldron, PhD, MSS
PART 1
Overview of
Population Health
Informatics

CHAPTER 1 Emerging Need for Population Health


Informatics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
CHAPTER 2 Population Health Informatics Workforce,
Competencies, and Training Programs . . . . . 31
© VLADGRIN/Shutterstock

1
© VLADGRIN/Shutterstock

CHAPTER 1
Emerging Need for
Population Health
Informatics
Ashish Joshi

KEY TERMS
Affordable Care Act (ACA) Health information technology
American Recovery and Reinvestment Act Population health
of 2009 (ARRA) Population health informatics (PopHI)
Cognitive fit theory Public health informatics (PHI)
Electronic health records (EHRs) Social determinants of health
Geographic information systems (GISs)

LEARNING OBJECTIVES
■■ Describe the growth of the Internet and social media in the 21st century.
■■ Define population health and its determinants.
■■ Distinguish between population and public health informatics.
■■ Assess the importance of social determinants of health data.
■■ Examine the intersection of technology and health care.
■■ List the challenges and opportunities related to population health
informatics solutions.
■■ List the factors to consider in the adoption and implementation of
population health informatics solutions.

3
4 Chapter 1 Emerging Need for Population Health Informatics

QUESTIONS FOR THOUGHT


■■ What is the significance of social determinants of health to enhance
population health outcomes?
■■ What opportunities does the growing usage of the Internet, mobile media,
and social media have on health?
■■ How can stakeholders and consumers address the challenges related to
implementation of population health informatics solutions in diverse settings?
■■ What opportunities do population health informatics solutions provide to
improve population health outcomes?

CHAPTER OUTLINE
I. Population Health and Its Determinants
II. The Growth of the Internet and Social Media
III. The Intersection of ICTs and Health Care
IV. The Emerging Role of Population Health Informatics
V. Challenges and Opportunities Related to PopHI
VI. Adoption of PopHI Solutions
VII. SMAART: An Innovative PopHI Conceptual Framework
VIII. Conclusion

▸▸ I. Population Health and Its Determinants

D
rivers of health outside the traditional medical care include social,
behavioral, and environmental determinants and need to be addressed
to improve health and diminish health disparities. The section below
­highlights the s­ ignificance of these factors in the improvement of population
health outcomes.

Defining Population Health


Population health describes the health needs of a defined group’s entire life span
(Evans, Barer, & Marmor, 1994). Population health is a linking thread to help under-
stand the determinants of health of populations (Evans et al., 1994). Social, ­economic,
and physical environments; personal health practices; individual capacity; and ­coping
skills all influence health status indicators. In turn, the health status indicators ­measure
population health (Kindig & Stoddart, 2003). Population health is also considered as
a summary measure that includes mortality and health-related quality of life (Field &
Gold, 1998) (TABLE 1.1).
Public health services are typically provided by government agencies and
include the core public health functions of health assessment, assurance, and policy
setting. Several differences exist among the various aspects of Population health and
public health, as shown here. Population health
I. Population Health and Its Determinants 5

TABLE 1.1 Overview of the Definitions of Population Health

Definition of Population Health Source

Exploring reasons about some Young, T. K. (2005). Population health:


populations being healthier than others Concepts and methods. New York, NY:
Oxford University Press.

Improve health and reduce health Health Canada. (1998). Taking action
inequalities of diverse populations on population health. Ottawa, Ontario:
Health Canada.

Paradigm for understanding why Young, T. K. (1998). Population health:


some populations have better health Concepts and methods. New York, NY:
outcomes than others Oxford University Press.

Focuses on factors that influence the Dunn, J. R., & Hayes, M. V. (1999). Toward
health of populations over the life course, a lexicon of population health. Canadian
variations in their patterns of occurrence Journal of Public Health, 90, S7.
resulting in actions, and policies to improve
health and well-being of populations

Highlight[s the] role of social and Kreuter, M., & Lezin, N. (2001). Improving
economic forces in combination with everyone’s quality of life: A primer on
biological and environmental factors that population health. Atlanta, GA: Group
shape the health of entire populations Health Community Foundation.

Health outcomes of a group of Kindig, D., & Stoddart, G. (2003). What is


individuals, including the distribution of population health? American Journal of
such outcomes within the group Public Health, 93(3), 380–383.

Improve[s] the health of populations Berwick, D. M., Nolan, T. W., & Whittington, J.
as one element in the Institute for (2008). The triple aim: Care, health, and
Healthcare Improvement’s (IHI) Triple Aim cost. Health Affairs, 27(3), 759–769.

Approach that fosters decision making Bostic, R. W., Thornton, R. L., Rudd, E. C., &
by policymakers, allowing them to assess Sternthal, M. J. (2012). Health in all
the implications of non-health-related policies: The role of the US Department
policies of Housing and Urban Development and
present and future challenges. Health
Affairs, 31(9), 2130–2137.

■■ Is less associated with health departments at the government level (Stoto, 2013)
■■ Includes the healthcare delivery system and is seen as separate from govern-
mental public health (Stoto, 2013)
■■ Is more than the sum of its individual parts (Stoto, 2013)
■■ Includes a broader array of the determinants of health than is typical in public
health (Stiefel & Nolan, 2012)
■■ Has outcomes that go beyond state and local public health agencies and health-
care delivery systems (Ayana, 2016)
6 Chapter 1 Emerging Need for Population Health Informatics

Expand primary Promoting community Provide specific


healthcare training and population-based preventive services
activities

Improve access to
Expand insurance
coverage
Population Health healthcare delivery
system

Enhance prevention Incentives for


Improve quality of
and health promotion workplace wellness
care delivered
measures programs

FIGURE 1.1 The Affordable Care Act


Data from Affordable Care Act. (2011). Federal Sentencing Reporter, 23(3).

The Affordable Care Act (ACA) addresses population health in several ways
(ACA, 2011; see FIGURE 1.1). The ACA defined the affordable care organization
(ACO), which includes clinicians, hospitals, and other healthcare organizations. They
share mutual responsibility for the population of patients with the goal of improv-
ing health outcomes and reducing health costs and inefficiencies. A critical change
is required by key stakeholders at the cultural, operational, and financial levels to
improve population health. Collaboration among a variety of stakeholders (patients,
providers, health plans, employers, government, the private sector, and the local
community) is a vital component of the population health approach to strengthen
care delivery and improve the well-being of individuals and families.

Determinants of Population Health


Multiple determinants, including educational, social, behavioral, and ­environmental
factors, influence population health outcomes (Kindig & Stoddart, 2003; see ­FIGURE 1.2).
Improving population health requires partners across many sectors including public
health, healthcare organizations, community organizations, and businesses (Drum-
mond & Stoddart, 1995). Population health data help organizations to do the following
­(Parrish, 2010):
■■ Identify at-risk populations
■■ Close communication gaps among individuals, public health agencies, and
clinical care
■■ Identify cost-effective healthcare delivery models
■■ Provide access to available public health programs and services
■■ Improve population health decision making
Health and health problems result from a complex interplay of factors. Social
determinants play a key role in the health of each individual. Social determinants
of health have gained importance in recent health policy discussions. Existing liter-
ature has specified the importance of the social determinants of health in improving
the health of populations. Education level, employment, income, family and social
support, and community safety are all components of the social and economic deter-
minants of health (County of Los Angeles Public Health, 2013). Unhealthy behaviors
I. Population Health and Its Determinants 7

Social and economic


factors (education,
transportation,
poverty, income)
Quality of life

Environmental Multiple
factors (built stakeholders
Cultural context
environment, housing)

Multi-sector
Health behaviors Mortality and
collaborations
(diet, physical life expectancy
activity, smoking)

Technology Continuous
Healthcare services monitoring
(access, quality, and evaluation
and cost) Overall
well-being
Biology and genetics Programs and policies
(age, gender, family
Interventions
history, disease status) Outcomes
Innovations
assessment

FIGURE 1.2 Determinants of population health


Modified Parrish, R. G. 2010. Measuring population health outcomes. Preventing Chronic Disease,7(4): A71. Retrieved from http://www.cdc.gov/pcd/issues/2010
/jul/10_0005.htm

are commonly associated with the lower social and economic position of a popu-
lation or community. Poor education, lack of affordable housing, and insufficient
income affect not just the individuals and families who have fewer resources, but also
all the communities in which they live. Researchers estimate that access to quality
medical care may prevent less than 20% of avoidable deaths. The remaining 80%
of avoidable deaths are attributable to genetics (20%), and social, behavioral, and
environmental determinants of health (60%; Taylor et al., 2016). Improvements in
healthcare resources and other determinants are likely to have a large impact on
prevention and the management of some illnesses (Starfield, 2006).
Gathering social determinants of health data would result in effective risk
assessment to ultimately support population health management. It can help health-
care professionals to identify care gaps. Healthcare organizations can also get better
insight into individual drivers of patient engagement and can match individuals
to specific interventions, preventive services, or resources that are most likely to
enhance outcomes. Social determinants of health have not been sufficiently recog-
nized despite the knowledge of their impact on health outcomes and longevity. The
interventions that address social, behavioral, and environmental determinants of
health are also less developed. There is a need to generate integrated, e­ vidence-based
approaches to have a better impact on health outcome and lowering of healthcare
costs. This gap has slowed health policymakers in promoting innovative models of
care, even though these nonmedical determinants of health are worthy of attention.
Several challenges limit the integration of social determinants of health data. These
impact evidence-based decision making, resulting in barriers to improving overall pop-
ulation health. Some of these challenges are (Robert Wood Johnson Foundation, 2016):
8 Chapter 1 Emerging Need for Population Health Informatics

■■ Limited knowledge of what works best: Clinicians, healthcare providers, pro-


gram operators, and researchers are utilizing data on social determinants of
health to identify the best ways to collate and use these data so that guidelines
can be evidence based.
■■ Lack of standardization and tools: The absence of standard measures for collect-
ing data on social determinants leads to inconsistencies. This limits the analysis
and decisions that can be made using such data.
■■ Limited knowledge in connecting patient, population, and public health data: Devel-
opment of effective, targeted health interventions requires linking of data at mul-
tiple levels, from patient-level to population and social determinants of health.
■■ Health systems need to understand their communities better: Community needs
and requirements to create programs, policies, and interventions need to be
well understood.
■■ Sharing data across sectors: Data sharing and its utility in health decision
making presents a fundamental challenge that involves issues of trust, system
interoperability, sector, and workflows.
■■ Identifying and developing the right technologies: Integrating social determi-
nants of health data into electronic health records (EHRs) has also been a
major challenge. The main alternative to EHRs for the collection, sharing, and
use of social determinants of health data are custom technology, cloud-based
technology, and geo-visual analytics.
Some of the outcomes facilitated by the analysis of social determinants of health data
include the following (Falk, 2016):
■■ Increased advocacy to address health inequalities
■■ Better policymaking
■■ Improved health outcomes
■■ Cost-effective interventions
■■ Leadership action plans that positively impact safety, cost, and clinical outcomes
■■ Improved clinical decision making and evidence-based practice
■■ Improved practice guidelines
Different stakeholders have different interests, which are not often unified. Although
policymakers focus on health policy decision making, advocacy groups typically focus on
improving outcomes related to one disease or its determinant. If the goal is overall health
improvement, individual groups working in silos are not productive ­(Kindig & Stoddart,
2003). Population health improvement as a goal creates an overarching need for a popu-
lation health perspective that encompasses health outcomes across determinants.

▸▸ II. The Growth of the Internet


and Social Media
Information and communication technology (ICT) has continued to proliferate at
a rapid pace. The beginning of the 21st century has ushered in the possibility of an
unprecedented era of scientific discovery and promise. New ICTs are being explored
to effectively and efficiently communicate with, engage, and educate the diverse pub-
lic. Such technologies can be utilized as web-based apps, mobile phones, and alert
systems. Technology continues to improve (Maynard & Harper, 2011). Computers
II. The Growth of the Internet and Social Media 9

are now available at much lower, affordable prices. The Internet is a massive net-
work, connecting millions of computers (FIGURES 1.3 and 1.4). The World Wide Web
allows individuals to access information via a computer, mobile telephone, tablet,
gaming device, or digital TV (Internet Live Stats, 2017).

4 billion

3 billion
Internet users

2 billion

1 billion

0
93 95 97 9 9 01 03 05 07 09 11 13 15
19 19 19 19 20 20 20 20 20 20 20 20
Year (as of July 1, 2017)

FIGURE 1.3 Internet users in the world


Data from Internet Live Stats. (2017). Internet users by region. Retrieved from http://www.internetlivestats.com/internet-users/

10.3% 9.3%
8.6%

17.1% 3.8% 0.7%

50.2%

Asia 50.2%
Europe 17.1%
Lat Am/Carib. 10.3%
Africa 9.3%
North America 8.6%
Middle East 3.8%
Oceania/Australia 0.7%

FIGURE 1.4 Internet users in the world by region


Reproduced from Internet World Stats. (2017b). World Internet users and 2017 population stats. Basis: 3,731,973,423 Internet users on March 31, 2017. Retrieved from
www.internetworldstats.com/stats.htm. Copyright © 2017, Miniwatts Marketing Group.
10 Chapter 1 Emerging Need for Population Health Informatics

North America 88.1%


Europe 77.4%
Australia/Oceania 68.1%
Latin America
59.6%
/Caribbean
Middle East 56.7%
World, Avg. 49.6%
Asia 45.2%
Africa 27.7%

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Penetration rate

FIGURE 1.5 Internet world penetration rates by regions of the world


Reproduced from Internet World Stats. (2017a). Internet usage statistics: The Internet big picture. Retrieved from http://www.internetworldstats.com/stats.htm

Currently, around 40% of the world’s population has an Internet connection


(Pew Research Center, 2016). As FIGURE 1.5 shows, North America has the highest
Internet penetration rate (88%), and Africa has the lowest Internet penetration rate
(27.7%) (Poushter, 2016; Internet World Stats, 2017a). Nearly half of Internet users
are from Asia (50.2%), as compared to 8.6% in North America.
Mobile and Internet technology use has become a daily, routine activity in most
parts of the world. Internet use is proliferating, especially for obtaining health infor-
mation (Atkinson, Saperstein, & Pleis, 2009). In addition to making and receiving
calls, cell phones are widely used for multiple purposes including sending messages
and capturing pictures and videos. Mobile health technologies constitute one of the
most rapidly growing markets globally. Growth is primarily attributed to an increas-
ing penetration of smartphones, tablets, and other mobile platforms, and the mHealth
Solutions Market is predicted to be worth 59.15 billion USD by 2020 (­ Markets and
Markets, 2017).
The use of mobile devices has transformed many aspects of health care. More than
half of the Internet users in the United States (65%) reported using social ­networking
sites in 2011 (Pew Research Center, 2016) (FIGURE 1.6). Facebook is the most popular
social networking site globally (Capurro et al., 2014), with an estimated 1 b­ illion active
users in total, including 580 million daily users. Twitter, with 500 m
­ illion users world-
wide, detects and predicts events and sentiments by observing users’ posts (tweets) in
real time (Capurro et al., 2014). Social networking sites offer a range of possibilities
for establishing multidirectional communication and interaction, as well as quickly
monitoring public sentiment and activity (Capurro et al., 2014).

▸▸ III. The Intersection of ICTs and Health Care


The advent of ICT has transformed healthcare delivery into patient-centered care.
ICTs allow the delivery of healthcare services, particularly to isolated communi-
ties. Integration of clinical and nonclinical data sources by using ICTs to enhance
­population health outcomes across diverse geographic settings is a growing need.
III. The Intersection of ICTs and Health Care 11

80

65%
61%
60

46%

40 43%
38%
29%

27%
20 16%

8%
13%
9%
2%
0
2005 2006 2007 2008 2009 20010 2011

Ever
Within the past 24 hours

FIGURE 1.6 Social media use by adults


Modified from Madden, M., & Zickuhr, K. (2011). 65% of online adults use social networking sites. Retrieved from http://www.pewinternet.org/2011/08/26/65-of
-online-adults-use-social-networking-sites/

Policymakers on a global scale are encouraging the use of such technologies to


improve health and healthcare systems. Mobile health technologies, remote wear-
able devices, and sensors have demonstrated immense potential in preventing
­diseases and improving well-being in numerous settings (Capurro et al., 2014).
Future technological innovation is going to keep transforming health care. Previ-
ously, technology played a minimal role in health, and healthcare professionals were
the only way to take care of people (Friede & O’Carroll, 1996). Technology is now
playing a significant role in health management information systems (HMISs), pub-
lic health surveillance, geographic information systems (GISs), and EHRs and
facilitates access to both public health programs and services. Technology is used
to monitor patterns of illness and to detect emerging or imminent threats to public
health (Araujo et al., 2009).
Public health professionals have been among the first users of information
technology. Technology can help providers identify and address nonmedical fac-
tors that affect population health (Institute of Medicine, 1997). More and more
organizations are beginning to record population-level data using cloud-based
12 Chapter 1 Emerging Need for Population Health Informatics

tools and technologies. Mobile devices including smartphones, tablet computers,


and remote monitoring devices have ample potential for use in disease prevention,
early risk identification, healthcare delivery, and timely support to populations liv-
ing in diverse settings (Centers for Disease Control and Prevention, 2006). These
emerging technologies present an opportunity to address global health challenges
in both developed and developing countries. Healthcare organizations around the
globe are forming technological infrastructures that enable several stakeholders
to make better informed, faster decisions and individuals to better manage their
health outside of the hospital setting (Deloitte, 2016). Innovative technologies cover
multiple areas including surveillance for disease, environmental monitoring, pol-
lution mitigation and prevention, behavior modification, screening, and chronic
disease management (Eng, 2004). The wide-scale adoption of health ­information
technology has enabled diverse stakeholders, such as providers, payers, and
­government agencies, to collaborate using new digital tools to improve the health
of defined populations.

▸▸ IV. The Emerging Role of Population


Health Informatics
Informatics is the science of information, where information is defined as data with
meaning (Bernstam, Smith, & Johnson, 2010). Informatics serves as a bridge across
practitioners and professions to support collaboration and electronic communica-
tion. Informatics tools provide benefits to both administrative and clinical aspects
of healthcare delivery and assist in collaborative practice by enhancing communica-
tion across team members. TABLE 1.2 lists some of the key global accomplishments
in the field of health informatics.

TABLE 1.2 Key Global Health Informatics Accomplishments

Year Country Key Accomplishments

1949 Germany First professional organization for Informatics was


founded

1950 United Kingdom Medical Informatics initiated in the UK

1952 United States First computer was used in clinical practice at


the American Society for Clinical Pathology
(Rappoport Arthur M-Bee)

1959 United States First CT scanner was developed by Robert Ledley,


one of the founding fathers of Informatics
IV. The Emerging Role of Population Health Informatics 13

1960 France Training programs for Informatics in France began

1968 Brazil Computers were first used in Medical care

1987 Hong Kong Hong Kong Society for Medical Informatics


(HKSMI) was established

1988 United States American Medical Informatics Association (AMIA)


established

1989 Switzerland International Medical Informatics Association


formed

1993 Nigeria First International Working Conference on Health


Informatics in Africa

1996 United States A 2-year fellowship program was established


by the Centers for Disease Control and
Prevention

1997 Argentina Biomedical Informatics group was established

2000 New Zealand Health Informatics program established in


New Zealand

2001 Canada Canada Health Infoway was established

2002 Australia Australasian college of health informatics


established

2004 United States Office of the National Coordinator for Health


Information Technology was created

2005 United States National Center for Public Health Informatics was
created by CDC

2006 Saudi Arabia Saudi Association for Health Informatics was


established

2009 United States The Health Information Technology for


Economic and Clinical Health (HITECH) Act
established

2017 India Digital Health Technology Ecosystem incorporated


into National Health Policy

Modified from Ng, S. K., & Wong, L. (2004). Accomplishments and challenges in bioinformatics. IT Professional, 6(1), 44–50.
14 Chapter 1 Emerging Need for Population Health Informatics

Public Health Informatics


Public health informatics (PHI) is the science of applying information-age
­technology to serve the specialized needs of public health (Friede, Blum, &
­McDonald, 1995). PHI is a systematic application of information, computer science,
and technology in the practice of public health (Yasnoff et al., 2000). It addresses
three core functions of public health: (1) assessment of population health, (2) p
­ olicy
development, and (3) assurance of the availability of high-quality public health
­services. The scope of PHI expands beyond conceptualization and design and
­development (Yasnoff et al., 2000).
Members of the public health and informatics community discussed key PHI
issues during the American Medical Informatics Association Meeting that was held
in Atlanta during May 15–17, 2001 (Yasnoff et al., 2001). The issues were related
to funding and governance; architecture and infrastructure; standards and vocabu-
lary; research, evaluation, and best practices; privacy, confidentiality, and security;
and training and workforce (Yasnoff et al., 2001). All stakeholders perceived the
role of information systems to be beneficial in improving the health of individuals
(Yasnoff et al., 2000). Some of the PHI-related challenges included developing inte-
grated national public health information systems, enhancing integration efforts
between public health and clinical care systems, and addressing the concerns of
information technology on confidentiality and privacy (Yasnoff et al., 2001).
A follow-up PHI conference was held in 2011 to revisit the PHI agenda devel-
oped in 2001 (Massoudi et al., 2012). Three key themes were identified: the need to
(1) increase communication and information sharing within the PHI community;
(2) improve evaluation methods, competency training, and the use of public health;
and (3) enhance leadership and coordination to move the field forward. Further
­recommendations included finding ways to strengthen prevention in the public
health and clinical continuum and to build health at the community level (Massoudi
et al., 2012).

Population Health Informatics


The U.S. HITECH Act of 2009 was designed to boost health information technol-
ogy adoption nationwide. President Obama signed the act into law on February
17, 2009, as part of the American Recovery and Reinvestment Act of 2009
(ARRA) economic stimulus bill. Some of the key processes included care coordi-
nation, cohort management, clinician engagement, and reporting and knowledge
management. Managing public health practice effectively and enhancing societal
well-being require multiple resources that provide accurate, high-quality, and timely
information. PHI focuses on population-level, preventive-based information. It also
serves as an applied science in relevant government settings with a central goal of
public health promotion (Yasnoff et al., 2000). PHI is a combination of medicine,
public health, computer science, and information processing (Kukafka, 2005). It has
also been defined as the application of ICTs in public health practice while integrat-
ing health research with information technology (Reeder, Hills, Demiris, Revere, &
Pina, 2011). Application of PHI principles provides unprecedented opportunities to
build healthier communities (Savel & Foldy, 2012).
A paradigm shift toward the area of population health informatics (PopHI)
has begun. This shift is because of the increasing focus on social health determinants
IV. The Emerging Role of Population Health Informatics 15

and use of technology in health care, combined with stakeholder initiatives including
the ACA, HITECH Act, and other relevant reforms (Vest & Gamm, 2010). PopHI
is the systematic application of information technologies and electronic informa-
tion to the improvement of the health and well-being of a defined community or
other target population (Kharrazi et al., 2017). For a health risk assessment to be
conducted effectively at the population level, aggregate data are needed from a vari-
ety of sources including health facilities, social services, law enforcement agencies,
departments of labor and industry, population-level surveys, and on-site inspec-
tions (O’Carroll, Yasnoff, Ward, Ripp, & Martin, 2003). PopHI can also be described
as an integration of social determinants of health data sources (both clinical and
nonclinical) by combining principles of ICT to enhance population health outcomes
across diverse geographic settings (Joshi, Arora, & Malhotra, 2017; FIGURE 1.7).
The current need for PopHI arises from dramatic improvements in informa-
tion technology, new pressures on the public health system, and changes in health-
care delivery. PopHI systems involve creation, storage, and processing of data to
generate information and knowledge. PopHI facilitates data-driven, well-informed,
evidence-based decision making for populations living in diverse settings. In addi-
tion to the informatics developments, elements of the PopHI system are a means
to generate and process data to achieve meaningful information and knowledge
about geographic areas that have concentrations of unfavorable health indicators
or are composed of populations of underserved groups (Kharrazi et al., 2017). The
development of such systems aims to help stakeholders gather timely and accurate
information about entire population groups and permit assessment of disparities of
health status among different populations (FIGURE 1.8).
PopHI also refers to the application of emerging technologies to improve the
health of populations (Eng, 2004). Some of the challenges that exist in relation to the
PopHI tools and technologies include privacy and security of patient data, confidenti-
ality, quality, sustainability, and the existing technology divide (Eng, 2004; FIGURE 1.9).

Information
systems

Social determinants
of health data
Population
health
data

Clinical care data

Computer
Geographic
science
setting

FIGURE 1.7 Intersections of population health, information systems, and computer science
among populations in diverse geographic settings
16 Chapter 1 Emerging Need for Population Health Informatics

Public health

Government Healthcare
agencies systems

PopHI

Employers Individuals

Insurers

FIGURE 1.8 Diverse stakeholder involvement in PopHI

Big data (increasing


velocity, volume,
veracity, and variety)

Data analytics
Interoperability
and interpretation

Lack of data
Privacy
standards

FIGURE 1.9 Challenges in the use of healthcare technologies


Modified from Harbinger Systems. (2016). Healthcare IT: Role of EDI in Affordable Care Act reforms. Retrieved from http://www.slideshare.net/hsplmkting/healthcare-it
-role-of-edi-in-affordable-care-act-reforms

Despite these challenges, health information technology, including mobile


health technology, holds significant potential for engaging individuals in disease
prevention and health promotion. It provides individuals with the necessary tools
to record their data and make data meaningful. More research is needed to assess
when, where, and for whom the population health technologies are efficacious.
TABLE 1.3 lists the key comparisons between PopHI and PHI.

▸▸ V. Challenges and Opportunities


Related to PopHI
Experts at a symposium sponsored by the National Library of Medicine identi-
fied six key domains of PopHI as significant (Kharrazi et al., 2017). Symposium
attendees included national experts and leading researchers in academia, the public
sector, provider organizations, and the information technology industry. These six
domains were as follows:
V. Challenges and Opportunities Related to PopHI 17

TABLE 1.3 Distinguishing Between Population Informatics and Public Health


Informatics

Population Health Informatics Public Health Informatics


(PopHI) (PHI)

Context Both governmental and Predominantly governmental


nongovernmental context

Common Total population Total population


intervention Target population Health departments
targets Healthcare organizations
Healthcare systems
Nongovernmental organizations

Main Outreach and prevention Assessment


operational Care integration Prevention
goals Disease management Assurance

Action arm Population health organizations Public health agencies


Care management organizations Not-for-profit and
nongovernmental
organizations

Key Provider and payer systems Federal, state, and local


stakeholders Government and community governments

Key Capturing nonmedical information Expanding public health IT


information Interoperability across sectors systems
challenges Medical and public health
interoperability

Modified from Kharrazi, H., Lasser, E. C., Yasnoff, W. A., Loonsk, J., Advani, A., Lehmann, H. P., . . . Weiner, J. P. (2017). A proposed
national research and development agenda for population health informatics: Summary recommendations from a national expert
workshop. Journal of the American Medical Informatics Association, 24(1), 2–12.

■■ Interoperability and information infrastructure: Having an interoperable plat-


form that can facilitate data sharing can potentially help advance the agenda
of PopHI.
■■ Cross-organization collaboration: Well-established programs or policies for
population health data sharing across diverse stakeholders do not exist.
■■ PopHI-based indicators and metrics: There is a need to have an understand-
ing of how advanced population health metrics can be derived from the health
information technology systems.
■■ Applying PopHI within integrated provider systems: Current state-of-the-art
tools represent an imbalance between focusing on the population vs. individual
providers.
18 Chapter 1 Emerging Need for Population Health Informatics

■■ Computer science and informatics methods for population health: There is a great
potential to utilize some of the computational methods from the field of com-
puter science to address the challenges of population health data integration
and analysis.
■■ Integration of social and nonmedical factors into PopHI systems: Linking social
and other nonmedical information with clinical data can enhance population
health methods and models.
For each of the domains identified, existing challenges and potential oppor-
tunities were assessed, alongside future research directions to address them
(TABLE 1.4).

TABLE 1.4 Challenges and Opportunities Across Population


Health Domains

Challenges and Research and Development


Domains Opportunities Issues

Interoperability Need for a clear, shared Methods for securely and


and information vision for a common, privately linking patient medical
infrastructure interoperable, and robust records across stakeholders
information infrastructure Promote a shared knowledge
Need for effective patient base for community health trends
identification methods to and population decision support
share data across systems Design end-user tools that
Inconsistent adoption of incorporate usability methods
interoperability standards and heuristics
Challenges associated with Foster the integration of social
silo functions and service science data into PopHI’s
provisions overarching architecture

Cross- Collaboration challenges Consensus on what data to


organization among stakeholders collect, integrate, and share as
collaboration Limited PopHI data use and part of PopHI
exchange agreements Discover and share new PopHI
Lack of aligned incentives analytic solutions and models
Instability of many among stakeholders
partnerships between Define population health
private and public data-sharing methods using
organizations established standards
Difficulty of blending Develop a set of metrics and
medical, public health, decision support guidelines
and consumer-targeted Create methods to assess the
interventions. quality of shared data and
techniques for linking disparate
data sources
V. Challenges and Opportunities Related to PopHI 19

PopHI-based Understanding how new Develop actionable predictive


indicators and data sources, such as models for population health
metrics patient-generated data and metrics
unstructured EHR data, can Build a health information
be utilized technology framework to capture
Need appropriate and integrate patient-reported
informatics methods for outcomes on the population
improving the reliability, scale
accessibility, and Create a methodology to align
comparability of such existing population health
measures metrics across programs
Develop a prioritized Establish a framework to support
population/community the roll-out of new population-
report card health–focused metrics by
expanding collection of critical
data elements

Applying Lack of appropriate Integration of practice needs


PopHI within population health for population health data
integrated electronic quality measures management and governance
provider Absence of proof-of- Improvement of human factors
systems concept and return- and workflow issues for all
on-investment of stakeholders
enterprise-level tool Identification of a unifying
implementation framework for PopHI
Up-to-date meaningful infrastructure and stakeholder
use policy, and a lack of incentives for adoption
governance structures for
effective and efficient data
sharing

Computer Heterogeneity and Develop and disseminate a “grand


science and complexity of population computing challenge” for PopHI
informatics health data sources Encourage collaboration
methods for Privacy issues associated between computer scientists
population with population-level and trigger the development of
health analytics advanced, innovative methods
Limited collaboration Develop synthetic population-level
between health information datasets that can be shared freely
technology and population Develop guidelines for large-
health experts scale data sharing as well as
Lack of standardized data analytic frameworks for non-
architectures for population health researchers
health Advance interdisciplinary
research in applied PopHI
focus areas, such as change
management and workflow
reasoning

(continues)
20 Chapter 1 Emerging Need for Population Health Informatics

TABLE 1.4 Challenges and Opportunities Across Population


Health Domains (continued )

Challenges and Research and Development


Domains Opportunities Issues

Integration Poor understanding of the Solutions need to integrate


of social and information that needs nonpersonal data to person-
nonmedical to remain protected or specific data
factors into confidential when using Develop population-based
PopHI systems nonclinical data decision-support tools for both
public health/community officials
and clinicians
Develop analytic tools that work
across disparate population
health data types

Modified from Kharrazi, H., Lasser, E. C., Yasnoff, W. A., Loonsk, J., Advani, A., Lehmann, H. P., . . . Weiner, J. P. (2017). A proposed
national research and development agenda for population health informatics: Summary recommendations from a national expert
workshop. Journal of the American Medical Informatics Association, 24(1), 2–12.

▸▸ VI. Adoption of PopHI Solutions


Apart from the challenges, opportunities, and research and development issues
related to PopHI, the following 13 overarching themes of PopHI were identified
(Kharrazi et al., 2017):
■■ Policy alignment: There is a need to align the PopHI strategies with desired out-
comes that will facilitate adoption and implementation of appropriate PopHI
solutions.
■■ Data governance: Data governance and data privacy policies need to be in place
to ensure data sharing agreements so that it can further facilitate adoption and
implementation of PopHI solutions.
■■ Data quality: A suboptimal rate of completeness, accuracy, timeliness, reliabil-
ity, or validity of a data source can produce uncertainty when the data are incor-
porated into PopHI solutions.
■■ Data management: Differences in granularity and heterogeneity across various
data sources create many data management challenges.
■■ Sustainability and incentives: Lack of funding and difficulty attracting new
funding streams may affect the scalability of a project and limit the flexibility of
its core business model.
■■ Population metrics: The lack of accurate and reproducible e-metrics may reduce
the effectiveness of PopHI solutions.
■■ Interoperability standards: Limited PopHI standards and interoperability
frameworks affect the development of new PopHI solutions.
■■ Stakeholder collaboration: If stakeholders do not collaborate effectively, this will
produce suboptimal results.
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One instant in close speech
With them he doth confer:
God-sped, he hasteneth on,
That anxious traveller...

I was that man—in a dream:


And each world's night in vain
I patient wait on sleep to unveil
Those vivid hills again.

Would that they three could know


How yet burns on in me
Love—from one lost in Paradise—
For their grave courtesy.

ALEXANDER

It was the Great Alexander,


Capped with a golden helm,
Sate in the ages, in his floating ship,
In a dead calm.

Voices of sea-maids singing


Wandered across the deep:
The sailors labouring on their oars
Rowed, as in sleep.

All the high pomp of Asia,


Charmed by that siren lay,
Out of their weary and dreaming minds,
Faded away.
Like a bold boy sate their Captain,
His glamour withered and gone,
In the souls of his brooding mariners,
While the song pined on.

Time, like a falling dew,


Life, like the scene of a dream,
Laid between slumber and slumber,
Only did seem....

O Alexander, then,
In all us mortals too,
Wax thou not bold—too bold
On the wave dark-blue!

Come the calm, infinite night,


Who then will hear
Aught save the singing
Of the sea-maids clear?

THE REAWAKENING

Green in light are the hills, and a calm wind flowing


Filleth the void with a flood of the fragrance of Spring;
Wings in this mansion of life are coming and going,
Voices of unseen loveliness carol and sing.

Coloured with buds of delight the boughs are swaying,


Beauty walks in the woods, and wherever she rove
Flowers from wintry sleep, her enchantment obeying,
Stir in the deep of her dream, reawaken to love.
Oh, now begone sullen care—this light is my seeing;
I am the palace, and mine are its windows and walls;
Daybreak is come, and life from the darkness of being
Springs, like a child from the womb, when the lonely one calls.

THE VACANT DAY

As I did walk in meadows green


I heard the summer noon resound
With call of myriad things unseen
That leapt and crept upon the ground.

High overhead the windless air


Throbbed with the homesick coursing cry
Of swallows that did everywhere
Wake echo in the sky.

Beside me, too, clear waters coursed


Which willow branches, lapsing low,
Breaking their crystal gliding forced
To sing as they did flow.

I listened; and my heart was dumb


With praise no language could express;
Longing in vain for him to come
Who had breathed such blessedness.

On this fair world, wherein we pass


So chequered and so brief a stay;
And yearned in spirit to learn, alas,
What kept him still away.
THE FLIGHT

How do the days press on, and lay


Their fallen locks at evening down,
Whileas the stars in darkness play
And moonbeams weave a crown—

A crown of flower-like light in heaven,


Where in the hollow arch of space
Morn's mistress dreams, and the Pleiads seven
Stand watch about her place.

Stand watch—O days no number keep


Of hours when this dark clay is blind.
When the world's clocks are dumb in sleep
'Tis then I seek my kind.

THE TWO HOUSES

In the strange city of Life


Two houses I know well:
One wherein Silence a garden hath,
And one where Dark doth dwell.

Roof unto roof they stand,


Shadowing the dizzied street,
Where Vanity flaunts her gilded booths
In the noontide glare and heat.
Green-graped upon their walls
An ancient hoary vine
Hath clustered their carven, lichenous stones
With tendril serpentine.

And ever and anon,


Dazed in that clamorous throng,
I thirst for the soundless fount that stills
Those orchards mute of song.

Knock, knock, nor knock in vain:


Heart all thy secrets tell
Where Silence a fast-sealed garden hath,
Where Dark doth dwell.

FOR ALL THE GRIEF

For all the grief I have given with words


May now a few clear flowers blow,
In the dust, and the heat, and the silence of birds,
Where the lonely go.

For the thing unsaid that heart asked of me


Be a dark, cool water calling—calling
To the footsore, benighted, solitary,
When the shadows are falling.

O, be beauty for all my blindness,


A moon in the air where the weary wend,
And dews burdened with loving-kindness
In the dark of the end.
THE SCRIBE

What lovely things


Thy hand hath made:
The smooth-plumed bird
In its emerald shade,
The seed of the grass,
The speck of stone
Which the wayfaring ant
Stirs—and hastes on!

Though I should sit


By some tarn in thy hills,
Using its ink
As the spirit wills
To write of Earth's wonders,
Its live, willed things,
Flit would the ages
On soundless wings
Ere unto Z
My pen drew nigh;
Leviathan told,
And the honey-fly:
And still would remain
My wit to try—
My worn reeds broken,
The dark tarn dry,
All words forgotten—
Thou, Lord, and I.
FARE WELL

When I lie where shades of darkness


Shall no more assail mine eyes,
Nor the rain make lamentation
When the wind sighs;
How will fare the world whose wonder
Was the very proof of me?
Memory fades, must the remembered
Perishing be?

Oh, when this my dust surrenders


Hand, foot, lip, to dust again,
May these loved and loving faces
Please other men!
May the rusting harvest hedgerow
Still the Traveller's Joy entwine,
And as happy children gather
Posies once mine.

Look thy last on all things lovely,


Every hour. Let no night
Seal thy sense in deathly slumber
Till to delight
Thou have paid thy utmost blessing;
Since that all things thou wouldst praise
Beauty took from those who loved them
In other days.

Printed by T. and A. CONSTABLE, Printers to His Majesty


at the Edinburgh University Press
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