CS/B.

PHARM(N)/EVEN/SEM-4/4129/2022-2023/I140
MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY, WEST BENGAL
Paper Code : PT418 Pharmacology I
UPID : 004129

Time Allotted : 3 Hours Full Marks :70

The Figures in the margin indicate full marks.
Candidate are required to give their answers in their own words as far as practicable

Group-A (Very Short Answer Type Question)

1. Answer any ten of the following : [ 1 x 10 = 10 ]
(I) Parenteral administration produces a more...................response than oral administration.
(II) What is idiosyncratic reaction of a drug ?
(III) Spinal cord is not a part of ................... nervous system
(IV) Preganglionic neurons lie within _____________
(V) ......................... routes of drug administration is most convenient and would not
require skilled Health care supervision
(VI) The main mechanism of most drugs absorption in GI tract is
(VII) ................... cells is found in peripheral nervous system
(VIII) Bipolar neurons have ___________
(IX) Spinal cord and brain are wrapped in protective membranes known as ___________
(X) Metabolic transformation (phase 1) is.....................
(XI) ................... route of drug administration where Small amount of medication is injected just
beneath epidermis
(XII) Biotransformation of the drugs is to render them...................

Group-B (Short Answer Type Question)

Answer any three of the following : [ 5 x 3 = 15 ]
2. Explain the JAK-STAT binding receptor transduction mechanism. [5]
3. What are the essential drugs and give examples. [5]
4. Write the pharmacology of physostigmin. [5]
5. Explain the pharmacodynamic drug-drug interactions . [5]
6. Write a note on metabolism of drugs by Phase I reaction. [5]

Group-C (Long Answer Type Question)

Answer any three of the following : [ 15 x 3 = 45 ]
7. What are G-protein coupled receptors? Explain about the G-protein couple signal transduction [ 15 ]
mechanism.
8. Describe the neurohumoral transmission with examples. [ 15 ]
9. What are the types of drug interactions? Explain the factor affecting the pharmacokinetics drug-drug [ 15 ]
interaction.
10. Write the classification of parasympathomimetics. Explain the pharmacological actions, side effects and [ 15 ]
uses of acetylcholine.
11. Write the classification of anti epileptics with examples. Explain the pharmacology, side effects and uses [ 15 ]
Of phenytoin.

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