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Procedure For Inspection and Maintenance of Desiccators
Procedure For Inspection and Maintenance of Desiccators
The purpose of this SOP is to lay down a procedure for Issuance, Usage and Disposal of
Desiccant.
This SOP is applicable for the Inspection and Maintenance of Desiccators Issuance, Usage and
Disposal of Desiccant in Quality Control Department at manufacturing facility of
Pharmaceutical Industry.
General Note:
Clean the desiccator with a free lint cloth before adding the silica, always avoid moisture.
Procedure:
Store the dried silica that is left back after adding a quantity to the desiccator in an oven
constantly.
Dried silica is placed in a desiccator for further use of the desiccator and record the date of
issuance Form01.
For glass desiccator apply silicone wax to the ends of the both lower cup and upper lid of the
desiccator.
Always keep the desiccator in closed condition so as to avoid the moisture to enter the
desiccator.
Observe the silica visually for its colour changes, change the desiccate after two weeks.
If colour change from blue to pink dry the silica in an oven at 105°C for 3hours and document it.
Form01
If the colour change from pink to white, dispose the silica and record it Form02.
Place a tag on the desiccator mentioning the details of desiccator number, date of change of silica
and expiry date, and status of the silica.