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Genetics, 6e (Brooker)
Chapter 9 Molecular Structure of DNA and RNA
Answer: C
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 1. Remember
Learning Outcome: 09.01.02 Analyze the results of (1) Griffith, (2) Avery, MacLeod, and
McCarty, and (3) Hershey and Chase, and explain how they indicate that DNA is the genetic
material.
Accessibility: Keyboard Navigation
2) The fact that the type R and S strains of Streptococcus pneumoniae that Griffith worked with
possessed small differences in capsule structure satisfies which of the following criteria for
genetic material?
A) Transmission
B) Replication
C) Information
D) Variation
Answer: D
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 2. Understand
Learning Outcome: 09.01.01 Describe the four criteria that the genetic material must meet.
Accessibility: Keyboard Navigation
3) The individuals who determined that Griffith's transforming principle was DNA were
________.
A) Hershey and Chase
B) Avery, Macleod, and McCarty
C) Watson and Crick
D) Creighton and McClintock
Answer: B
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 1. Remember
Learning Outcome: 09.01.02 Analyze the results of (1) Griffith, (2) Avery, MacLeod, and
McCarty, and (3) Hershey and Chase, and explain how they indicate that DNA is the genetic
material.
Accessibility: Keyboard Navigation
1
Copyright © 2018 McGraw-Hill
4) These individuals determined that DNA was responsible for the process of transduction in T2
phage.
A) Hershey and Chase
B) Avery, Macleod, and McCarty
C) Watson and Crick
D) Creighton and McClintock
Answer: A
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 1. Remember
Learning Outcome: 09.01.02 Analyze the results of (1) Griffith, (2) Avery, MacLeod, and
McCarty, and (3) Hershey and Chase, and explain how they indicate that DNA is the genetic
material.
Accessibility: Keyboard Navigation
Answer: C
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 2. Understand
Learning Outcome: 09.01.02 Analyze the results of (1) Griffith, (2) Avery, MacLeod, and
McCarty, and (3) Hershey and Chase, and explain how they indicate that DNA is the genetic
material.
Accessibility: Keyboard Navigation
Answer: D
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 2. Understand
Learning Outcome: 09.01.02 Analyze the results of (1) Griffith, (2) Avery, MacLeod, and
McCarty, and (3) Hershey and Chase, and explain how they indicate that DNA is the genetic
material.
Accessibility: Keyboard Navigation
2
Copyright © 2018 McGraw-Hill
7) The building blocks of DNA are called ________.
A) amino acids
B) codons
C) nucleotides
D) alleles
Answer: C
Section: 09.02
Topic: Overview of DNA and RNA Structure
Bloom's: 1. Remember
Learning Outcome: 09.02.01 Define nucleic acid.
Accessibility: Keyboard Navigation
Answer: A
Section: 09.03
Topic: Nucleotide Structure
Bloom's: 2. Understand
Learning Outcome: 09.03.01 Describe the structure of a nucleotide.
Accessibility: Keyboard Navigation
Answer: B
Section: 09.03
Topic: Nucleotide Structure
Bloom's: 2. Understand
Learning Outcome: 09.03.02 Compare and contrast the structures of nucleotides found in DNA
and in RNA.
Accessibility: Keyboard Navigation
3
Copyright © 2018 McGraw-Hill
10) Which base is not found in DNA?
A) Cytosine
B) Guanine
C) Thymidine
D) Adenine
E) Uracil
Answer: E
Section: 09.03
Topic: Nucleotide Structure
Bloom's: 1. Remember
Learning Outcome: 09.03.02 Compare and contrast the structures of nucleotides found in DNA
and in RNA.
Accessibility: Keyboard Navigation
Answer: D
Section: 09.04
Topic: Structure of a DNA Strand
Bloom's: 1. Remember
Learning Outcome: 09.04.01 Describe the structural features of a DNA strand.
Accessibility: Keyboard Navigation
12) The individual(s) who used ball and stick models to identify the three-dimensional structure
of proteins was ________.
A) Franklin
B) Watson and Crick
C) Hershey and Chase
D) Pauling
E) Chargaff
Answer: D
Section: 09.05
Topic: Discovery of the Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.05.01 Outline the key experiments that led to the discovery of the DNA
double helix.
Accessibility: Keyboard Navigation
4
Copyright © 2018 McGraw-Hill
13) What is the directionality of the DNA molecule?
A) Front to back
B) Top to bottom
C) 5' to 3'
D) 3' to 5'
E) All DNA molecules are different in their directionality
Answer: C
Section: 09.04
Topic: Structure of a DNA Strand
Bloom's: 1. Remember
Learning Outcome: 09.04.01 Describe the structural features of a DNA strand.
Accessibility: Keyboard Navigation
14) The researcher(s) who initially used X-ray diffraction to gather information on the DNA
molecule was ________.
A) Franklin
B) Watson and Crick
C) Hershey and Chase
D) Pauling
E) Chargaff
Answer: A
Section: 09.05
Topic: Discovery of the Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.05.01 Outline the key experiments that led to the discovery of the DNA
double helix.
Accessibility: Keyboard Navigation
15) What were the conclusions of Franklin's work regarding the structure of DNA?
A) It did not have a helical structure.
B) The helix had more than one strand.
C) The helix contained about 1 bases per turn.
D) The helix had only one strand.
Answer: B
Section: 09.05
Topic: Discovery of the Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.05.01 Outline the key experiments that led to the discovery of the DNA
double helix.
Accessibility: Keyboard Navigation
5
Copyright © 2018 McGraw-Hill
16) According to Chargaff's rule, if the DNA of a species contains 20% adenine, what percent of
guanine will it contain?
A) 20%
B) 30%
C) 50%
D) 75%
Answer: B
Section: 09.05
Topic: Discovery of the Double Helix
Bloom's: 4. Analyze
Learning Outcome: 09.05.01 Outline the key experiments that led to the discovery of the DNA
double helix.
Accessibility: Keyboard Navigation
17) The first group of researchers to correctly identify the double-helix structure of DNA were
________.
A) McClintock and Franklin
B) Hershey and Chase
C) Pauling and Avery
D) Watson and Crick
Answer: D
Section: 09.05
Topic: Discovery of the Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.05.01 Outline the key experiments that led to the discovery of the DNA
double helix.
Accessibility: Keyboard Navigation
18) In a double-helix DNA strand, the adenine on one strand forms a hydrogen bond with a(n)
________ on the other strand.
A) adenine
B) guanine
C) thymine
D) cytosine
Answer: C
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 2. Understand
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
6
Copyright © 2018 McGraw-Hill
19) How many bases are necessary to complete three complete twists (1080 degrees) of a DNA
helix?
A) 5
B) 10
C) 30
D) 60
Answer: C
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 3. Apply
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
20) The fact that the helixes of the DNA strand are arranged in opposite directions gives DNA its
________ characteristics.
A) antiparallel
B) complementary
C) redundant
D) water-soluble
Answer: A
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 2. Understand
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
Answer: D
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 3. Apply
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
7
Copyright © 2018 McGraw-Hill
22) What DNA form is most common in living organisms?
A) B DNA
B) Z DNA
C) Triplex DNA
Answer: A
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.06.02 Compare and contrast B DNA and Z DNA.
Accessibility: Keyboard Navigation
Answer: B
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.06.02 Compare and contrast B DNA and Z DNA.
Accessibility: Keyboard Navigation
24) In the Hershey-Chase experiments, the protein coat of the bacteriophage was labeled with the
32P radioisotope.
Answer: FALSE
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 1. Remember
Learning Outcome: 09.01.02 Analyze the results of (1) Griffith, (2) Avery, MacLeod, and
McCarty, and (3) Hershey and Chase, and explain how they indicate that DNA is the genetic
material.
Accessibility: Keyboard Navigation
Answer: FALSE
Section: 09.03
Topic: Nucleotide Structure
Bloom's: 1. Remember
Learning Outcome: 09.03.01 Describe the structure of a nucleotide.
Accessibility: Keyboard Navigation
8
Copyright © 2018 McGraw-Hill
26) B DNA is recognized as a left-handed molecule.
Answer: FALSE
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
27) A purine on one strand of the DNA is always paired with a pyrimidine on the other strand.
Answer: TRUE
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
28) The helical shape of the DNA contains major and minor grooves, which assist in the
regulating of gene expression.
Answer: TRUE
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
Answer: FALSE
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 2. Understand
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
9
Copyright © 2018 McGraw-Hill
30) Avery used the enzyme ________ to remove the proteins from the cell extracts.
A) protease
B) DNase
C) RNase
D) All of the answers are correct
Answer: A
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 1. Remember
Learning Outcome: 09.01.02 Analyze the results of (1) Griffith, (2) Avery, MacLeod, and
McCarty, and (3) Hershey and Chase, and explain how they indicate that DNA is the genetic
material.
Accessibility: Keyboard Navigation
31) The ________ was labeled using the radioisotope 32P in the Hershey-Chase experiments.
A) RNA
B) DNA
C) protein
D) carbohydrates
Answer: B
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 1. Remember
Learning Outcome: 09.01.02 Analyze the results of (1) Griffith, (2) Avery, MacLeod, and
McCarty, and (3) Hershey and Chase, and explain how they indicate that DNA is the genetic
material.
Accessibility: Keyboard Navigation
32) Cells are treated with a drug that blocks purine synthesis. Which bases would not be made in
those treated cells?
A) cytosine, thymine, and uracil
B) adenine and guanine
C) adenine and thymine
D) cytosine and guanine
Answer: B
Section: 09.03
Topic: Nucleotide Structure
Bloom's: 3. Apply
Learning Outcome: 09.03.01 Describe the structure of a nucleotide.
Accessibility: Keyboard Navigation
10
Copyright © 2018 McGraw-Hill
33) The pyrimidine bases are ________.
A) cytosine, thymine, and uracil
B) adenine and guanine
C) adenine and thymine
D) cytosine and guanine
Answer: A
Section: 09.03
Topic: Nucleotide Structure
Bloom's: 1. Remember
Learning Outcome: 09.03.01 Describe the structure of a nucleotide.
Accessibility: Keyboard Navigation
34) The idea that the adenine and thymine bases of the DNA interact in some manner was first
proposed by ________.
A) Watson and Crick
B) Franklin
C) Pauling
D) Chargaff
Answer: D
Section: 09.05
Topic: Discovery of the Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.05.01 Outline the key experiments that led to the discovery of the DNA
double helix.
Accessibility: Keyboard Navigation
35) Adenine and thymine form ________ hydrogen bonds between them, while cytosine and
guanine form ________ bonds.
A) 2, 3
B) 3, 4
C) 3, 2
D) 4, 3
Answer: A
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 1. Remember
Learning Outcome: 09.06.01 Outline the key structural features of the DNA double helix.
Accessibility: Keyboard Navigation
11
Copyright © 2018 McGraw-Hill
36) What is one of the criteria that all genetic material must meet?
A) It does not contain the information necessary to construct the entire organism.
B) It must be passed from offspring to parent.
C) It must be able to be copied.
D) It must have a limited amount of variation.
Answer: C
Section: 09.01
Topic: Identification of DNA as the Genetic Material
Bloom's: 2. Understand
Learning Outcome: 09.01.01 Describe the four criteria that the genetic material must meet.
Accessibility: Keyboard Navigation
37) Which of the following is a correct matching of the researcher with their discovery?
A) Pauling provided information on primary structure in biological molecules.
B) Franklin suggested that DNA was a helix with more than one strand and that there were about
10 bases per turn of the DNA.
C) Watson and Crick collected a large amount of X-ray data on the structure of DNA.
D) Chargaff demonstrated that the adenine and cytosine bases and the uracil and guanine bases
interacted in some manner.
Answer: B
Section: 09.05
Topic: Discovery of the Double Helix
Bloom's: 2. Understand
Learning Outcome: 09.05.01 Outline the key experiments that led to the discovery of the DNA
double helix.
Accessibility: Keyboard Navigation
Answer: B
Section: 09.02
Topic: Overview of DNA and RNA Structure
Bloom's: 2. Understand
Learning Outcome: 09.02.02 Describe the four levels of complexity of DNA.
Accessibility: Keyboard Navigation
12
Copyright © 2018 McGraw-Hill
39) An RNA strand with sequence 5'–GUACAAUGACUUAUGUAC–3' can potentially form
which structure?
A) Bulge loop
B) Internal loop
C) Multibranched junction
D) Stem-loop
Answer: A
Section: 09.07
Topic: RNA Structure
Bloom's: 4. Analyze
Learning Outcome: 09.07.01 Outline the key structural features of RNA.
Accessibility: Keyboard Navigation
40) Select the DNA strand that would form a triple helix with the following double helix.
5'–CTACTTAGAAGGGGAAATACG–3'
3'–GATGAATCTTCCCCTTTACGC–5'
A) 3'–TTTCCCCTTCT–5'
B) 5'–TTTCCCCTTCT–3'
C) 3'–AAAGGGGAAGA–5'
D) 5'–AAAGGGGAAGA–3'
Answer: A
Section: 09.06
Topic: Structure of the DNA Double Helix
Bloom's: 3. Apply
Learning Outcome: 09.06.03 Describe how triplex DNA is formed.
Accessibility: Keyboard Navigation
13
Copyright © 2018 McGraw-Hill
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welcomed by the colored as by the white members of the household.
Just before her arrival, a bottle of medicine with a strong odor of
Bourbon had been uncorked, and, afterward, set away. After the first
greetings were over, she exclaimed:
“I smell spirits. What have you been doing?”
Old Aunt Chloe, who had lingered in the room so as to be near
the beloved new-comer, turned with an air of triumph to her mistress,
who had often rebuked her belief in ghosts, and burst out with:
“Dar, Missus! Didn’t I allus tole yo dere was sperits in dis yere
house? Sometimes I see ’em, sometimes I hear ’em, an’ yo wood’n
b’lieve me; but now, Miss Lizzie’s done gone SMELL ’em!”
“The story,” said our host, with his inexhaustible humor and
irresistible brogue, “is of a man who died, and forthwith presented
himself at Heaven’s gate, requesting admittance.
‘Have ye bin to Purgatory, my mon?’ says St. Peter.
‘No, yer Riverence.’
‘Thin it’s no good. Ye’ll have to wait awhile.’
While the unlucky ‘Peri’ was slowly withdrawing, another
candidate approached, and the same question was asked him.
‘No, yer Riverence, but I’ve been married.’
‘Well, that’s all the same,’ says St. Peter; ‘Come in!’
At this, the first arrival taking heart of grace, advanced again, and
says he:
‘Plaze yer Riverence, I’ve been married twice!’
‘Away wid ye! Away wid ye!’ says St. Peter: ‘Heaven is no place
for fools!’”
DIALECTICAL.
The peculiarities of the Yankee dialect are most amusingly
exemplified by James Russell Lowell, in the Biglow Papers,
especially in the First Series, from which the following extract is
taken:
I ’spose you wonder where I be; I can’t tell fur the soul o’ me
Exactly where I be myself, meanin’ by thet, the hull o’ me.
When I left hum, I hed two legs, an’ they wa’n’t bad ones neither;
The scaliest trick they ever played, wuz bringin’ on me hither—
Now one on ’em’s I dunno where, they thought I was a-dyin’,
An’ cut it off, because they said ’twas kind of mortifyin’;
I’m willin to believe it wuz, and yet I can’t see, nuther,
Why one should take to feelin’ cheap a minute sooner ’n t’other,
Sence both wuz equilly to blame—but things is ez they be;
It took on so they took it off, an’ thet’s enough for me.
Where’s my left hand? Oh, darn it! now I recollect wut’s come on’t.
I haint no left hand but my right, and thet’s got jest a thumb on’t,
It aint so handy as it wuz to calkylate a sum on’t.
I’ve lost one eye, but then, I guess, by diligently usin’ it,
The other’ll see all I shall git by way of pay fer losin’ it.
I’ve hed some ribs broke, six I b’lieve, I haint kep’ no account of ’em;
When time to talk of pensions comes, we’ll settle the amount of ’em.
An’ talkin’ about broken ribs, it kinder brings to mind
One that I couldn’t never break—the one I left behind!
Ef you should see her, jest clean out the spout o’ your invention,
And pour the longest sweetnin’ in about a annooal pension;
And kinder hint, in case, you know, the critter should refuse to be
Consoled, I aint so expensive now to keep, as wut I used to be:—
There’s one eye less, ditto one arm, an’ then the leg that’s wooden,
Can be took off, an’ sot away, whenever there’s a pudden!
(Letter from Birdofreedom Sawin, a Mexican volunteer, to a friend
at home.)
ODE TO SPRING.
2 KT J.
An SA now I mean 2 write
2 U, sweet KT J,
The girl without a ||,
The belle of UTK.
This SA until U I C,
I pray U 2 to XQQ;
And not to burn in FIG
My young and 10der muse.
1 97½
After a “lovers’
quarrel,” when the party of the first part
——Meekly approached and knelt down at her feet,
Praying loud as before he had ranted,
That she would forgive him, and try to be sweet,
And said “Can’t you?” the dear girl re-canted.
SECRET CORRESPONDENCE.