POLYCYSTIC

OVARY
SYNDROME
( PCOS )
Introduction
PCOS is a complexe
endocrine disorder
characterized by
the chronic
anovulation,
hyperandrogenism,
and insulin
resistance.
 PATHOPHYSIOLOGY

- It is associated with the

development of numerous
small cysts in the ovaries.
The exact cause of PCOS is
unknown but it is believed
to involve a combination of
genetic and environmental
factors
RISK
FACTORS
- Family History of
PCOS

- Obesity

- Insulin Resistance

- High levels of
androgen
Diagnosing PCOS
Diagnosis involves a
combination of
medical history,
physical examination,
and laboratory tests
including hormone
levels and ultrasound
to detect ovarian
cysts.
LABORATORY TEST

- Hormonal assays:
elevated of
testosterone.

- Fasting glucose and

insulin levels.

- Lipid Profile: as
women with PCOS
are at increased of
risk for dyslipidemia.
 SIGNS AND SYMPTOMS

- IRREGULAR OR MISSED PERIOD

- HIRSUTISM
- ACNE AND OILY SKIN
- SCALP HAIR THINNING
- WEIGHT GAIN OR DIFFICULTY T
LOSS WEIGHT
-INFERTILITY DUE TO
ANOVULATION
THERAPEUTIC
MANAGEMENT :
Pharmacologic treatment

- Anti - androgens
(spironolactone)

- Metformin

— Clomiphene and
letrozole for fertility
treatments
Non
pharmacologic
treatment:
Life style
changes - is the
first line
treatment.
Thanks!