1.

The purpose of vaccination is to provide an initial exposure to an antigen to stimulate the formation of
Memory cells
Killer cells
Anaphylaxis
Complement

2.Release of which of the following antigens can not induce autoimmune disease * Myelin Basic protein
Sperm antigens
Lens proteins
RBC antigens

3.Graves' disease causes____whereas Hashimoto's disease causes ____.

glomerulonephritis; systemic vasculitis
hyperglycemia; hypoglycemia
hypothyroidism; hyperthyroidism
hyperthyroidism; hypothyroidism

4. Quantitative HIV RNA load can be detected by which of the following techniques? *

Western Blotting
Real-time RT-PCR
ICT
ELISA

5. Which viral receptor is involved in HIV attachment to the host cell? *

p24
gp120
p17
gp41

6. Genes that encode major antigens of especially virulent pathogens can be 1 point introduced intoattenuated viruses or
bacteria. The attenuated organism is used to infect the host and during replication express the gene product of the
pathogen, this constitute *

recombinant vector vaccine

DNA vaccine
killed vaccine
subunit vaccine

7. You had measles as a child. Which of the following best describes your immunity to measles? *

Naturally acquired active immunity

Artificially acquired active immunity
Naturally acquired passive immunity
Artificially acquired passive immunity
8. Protease enzyme
cleaves poly-protein into individual functional viral proteins
helps the virus attach to the host cell
integrates viral DNA into host genome
makes DNA from single-stranded RNA
9. Which of the following indicates why you will not get Pulmonary Tuberculosis as an adult as youwere vaccinated
by BCG as a child? *
Artificially acquired passive immunity
Naturally acquired active immunity
Naturally acquired passive immunity
Artificially acquired active immunity

10. Plasmids encoding antigenic protein from a pathogen that is directly injected into the cells where it expresses
constitute *
subunit vaccine
DNA vaccine
killed vaccine
recombinant vector vaccine

11. The best treatment for HIV infection is *

integrase inhibitors
highly active antiretroviral therapy (HAART)
reverse transcriptase inhibitors
protease inhibitors

12. Which of the following diseases affect neutrophils? *

DiGeorge's syndrome
Severe combined immunodeficiency disease (SCID)
Wiskott Aldrich syndrome (WAS)
Chronic granulomatous disease (CGD)

13. A male patient presents with severe and recurrent bacterial infections. Lab work confirms the patient is only infected
with certain bacteria due to a mutation in a gene for NADPH oxidase. Which of the following is the most likely?*
Leukocyte adhesion deficiency (LAD)
Bare lymphocyte syndrome (BLS)
DiGeorge's syndrome
Chronic granulomatous disease (CGD)

14.The process of weakening (less pathogenic) a pathogen is called *

conjugation
immunization
vaccination
Attenuation

15. Placental transfer of IgG from mother to fetus is a way of acquiring *

naturally acquired passive immunity

artificially acquired active immunity
naturally acquired active immunity
16. In order for HIV to attach, the host cell must have *
a CD4 antigen receptor and a cell specific co-receptor
a gp120 receptor
a CD8 receptor and a specific co-receptor
a CD4 receptor and a nonspecific universal receptor

17. The pol gene does NOT encode for which of the following enzymes? * protease
reverse transcriptase
RNA polymerase
integrase

18. A child presents with recurrent infections with bacteria, fungi, and viruses. 1 point The child was found IL-2R y chain
mutations, causing nearly complete deficiency of mature T and B lymphocytes. Which of the following does the patient
have? *
Leukocyte adhesion deficiency (LAD)
Wiscott-Aldrich syndrome (WAS)
Severe combined immunodeficiency disease (SCID)
Hereditary angioedema

19. A vaccination is a way of acquiring *

active artificial immunity
passive natural immunity
passive artificial immunity
active natural immunity

20. The important coreceptors for HIV to bind with CD4 receptors are: *

CCR4 and CXCR2

CCR5 and CXCR4
CCR4 and CXCR3
CCR4 and CXCR5

21.Which one of the following is the confirmatory diagnostic characteristic for 1 point Systemic Lupus Erythematosus
(SLE)? *
Auto-antibodies to acetylcholine receptor
Auto-antibodies to Thyroid Peroxidase
Auto-antibodies to DNA and DNA-associated protein
Auto-antibodies to renal and lung basement membranes

22.Auto-antibodies to adrenal cells are found in the case of *

Systemic Lupus Erythematosus (SLE)
Ankylosing spondylitis
Myasthenia gravis
Addison's Disease
23.Killed vaccines are theoretically much safer than live vaccines, but cannot replicate in hosts andcannot enter
intracellular antigen-presenting pathways. Which of the following killed vaccines is recommended for children but not
adults? *
Hepatitis B
Influenza
Hepatitis A
Inactivated (Salk) poliovirus