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Chapter 19
Reproductive System
Lecture Outline
Seeley’s ESSENTIALS OF
ANATOMY & PHYSIOLOGY
Eleventh Edition
Cinnamon VanPutte
Jennifer Regan
Andrew Russo

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The Reproductive System

• The human species could not survive without functional


male and female reproductive systems.
• The reproductive systems play essential roles in the
development of the structural and functional differences
between males and females, influence human behavior,
and produce offspring.
• However, a reproductive system, unlike other organ
systems, is not necessary for the survival of an individual
human.

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Reproductive System Functions

1. Production of gametes
2. Fertilization
3. Development and nourishment of a new individual
4. Production of reproductive hormones

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Major Reproductive Organs

Figure 19.1
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Female Reproductive System 1

• The female reproductive organs consist of the ovaries, the


uterine tubes, the uterus, the vagina, the external
genitalia, and the mammary glands.
• The internal reproductive organs of the female are located
within the pelvis, between the urinary bladder and the
rectum.

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Female Reproductive System 2

• The internal reproductive organs are held in place within


the pelvis by ligaments.
• The broad ligament spreads out on both sides of the
uterus and attaches to the ovaries and uterine tubes.

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Female Pelvis

Figure 19.8
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Female Reproductive Organs 1

Figure 19.9
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Ovaries 1

• Primary female reproductive organ


• Produces oocytes and sex hormones
• One on either side of uterus
• Ovarian ligaments: anchor ovaries to uterus
• Suspensory ligaments: anchor ovaries to pelvic cavity
• Mesovarium: attaches the ovaries to the broad ligament

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Female Reproductive Organs 2

• Ovarian follicle: groups of cells in ovaries that contain


oocytes
• Each of the ovarian follicles contains an oocyte, the
female reproductive cell.

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Structure of Ovary and Ovarian Follicles

Figure 19.10
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Oogenesis and Fertilization 1

• Oogenesis is the process of gamete production in females.


• Oogenesis begins before a female is born. By the fourth
month of development, the ovaries contain 5 million
oogonia which are the cells from which oocytes develop.
• Females are born with all of their oogonia (2 million), unlike
males that only begin to produce sperm during puberty.

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Oogenesis and Fertilization 2

• At puberty about 300,000 to 400,000 oogonia are left.


• Puberty to menopause, FSH stimulates several follicles to
begin developing during each menstrual cycle but only 1
follicle should be ovulated.

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Oogenesis and Fertilization 3

• Oocytes are swept into one of uterine tubes by fimbriae


during ovulation.
• If sperm is present in uterine tube during ovulation oocyte
could be fertilized.
• If fertilization occurs then zygote implants in uterus.
• Oocytes only live for 24 hours, so if no sperm is present at
ovulation no zygote develops, and oocyte dies.

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Maturation of the Oocyte and Follicle

Figure 19.11
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Female Reproductive Organs 3

Uterine (Fallopian) tubes:


• part of uterus which extends toward ovaries and receive
oocytes
• fimbriae are fringe-like structures around opening of
uterine tubes that help sweep oocyte into uterine tubes
• Fertilization usually occurs in the part of the uterine tube
near the ovary, called the ampulla
• tubal ligation (sterilization of female)

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Female Reproductive Organs 4

Uterus:
• pear sized structure located in pelvic cavity
• functions: receive, retain, and provide nourishment for
fertilized oocyte, where embryo resides and develops
• body: main part
• fundus: the part of the uterus superior to the entrance of
the uterine tubes
• cervix: narrow region that leads to vagina

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Female Reproductive Organs 5

Uterine wall layers:


• perimetrium (serous): outermost layer
• myometrium (muscular): middle layer, composed of
smooth muscle
• endometrium: innermost layer that is sloughed off during
menstruation

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Female Reproductive Organs 6

Vagina:
• extends from uterus to outside of body
• female copulation organ that receives penis during
intercourse
• allows menstrual flow
• involved in childbirth
• contains very muscular walls and a mucous membrane
• very acidic to keep bacteria out

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External Female Genitalia 1

Vulva:
• external female sex organs
• Includes mons pubis, labia majora and minora, clitoris,
prepuce and vestibule
Mons pubis:
• fatty layer of skin covering pubic symphysis

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External Female Genitalia 2

Labia majora:
• larger, outer folds of skin surrounding the entrance to the
vagina
• equivalent to male scrotum
Labia minora:
• thin, inner folds of skin surrounding entrance to the vagina

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External Female Genitalia 3

Clitoris:

• small erectile structure located in vestibule

• equivalent to male penis

Prepuce:

• where 2 labia minora unite over clitoris

Vestibule:

• space in which vagina and urethra are located

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Female External Genitalia

Figure 19.12
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Mammary Glands

• Organs of milk production in breasts


• Modified sweat glands
• Female breasts begin to enlarge during puberty
• Consists of lobes covered by adipose tissue
• Lobes, ducts, lobules are altered during lactation to
expel milk

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Anatomy of the Breast

Figure 19.13
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Female Puberty

• Begins between 11 to 13 years of age and is usually


completed by age 16
• Menarche first episode of menstrual bleeding
• Vagina, uterus, uterine tubes, and external genitalia
enlarge and fat is deposited in breasts and hips
• Elevated levels of estrogen and progesterone are secreted
by ovaries

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Female Sex Hormones 1

• Gonadotropin-releasing (GnRH) hormone is produced in


the hypothalamus and stimulates secretion of LH and FSH.
• Luteinizing Hormone (LH) is produced in the anterior
pituitary and causes ovulation.
• Follicle-stimulating hormone (FSH) is produced in the
anterior pituitary and prompts follicles in the ovaries to
begin development.

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Female Sex Hormones 2

Estrogen:
• proliferation of endometrial cells
• development of mammary glands (especially duct system)
• control of LH and FSH secretion
• development and maintenance of secondary sex
characteristics

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Female Sex Hormones 3

Progesterone:
• enlargement of endometrial cells and secretion of fluid
from uterine glands
• maintenance of pregnancy state
• development of mammary glands (especially alveoli)
• control of estrogen, FSH, and LH secretion
• development of secondary sex characteristics

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Menstrual Cycle 1

Menstrual cycle:
• series of changes that occur in sexually mature,
nonpregnant females
Menses:
• time when endometrium is shed from uterus
Average is 28 days and results from cyclical changes that
occur in endometrium

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Stages of Menstrual Cycle 1

Days 1 to 5 Menses (shedding of endometrium)


• menstrual bleeding (menses)
• estrogen and progesterone levels are low
• follicle begins to mature

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Stages of Menstrual Cycle 2

Days 6 to 13 Proliferative (between end of menses and


ovulation)
• endometrium rebuilds
• estrogen levels begin to increase
• progesterone levels remain low
• follicle matures

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Stages of Menstrual Cycle 3

Day 14 Ovulation
• oocyte is released due to LH
• estrogen levels high
• progesterone levels are increasing
• cervical mucus thins
Corpus luteum - mature follicle after ovulation
• degenerates if egg is not fertilized

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Stages of Menstrual Cycle 4

Days 15 to 28 Secretory (between ovulation and next


menses)
• endometrium is preparing for implantation
• estrogen levels decrease (low)
• progesterone levels high
• cervical mucus thickens

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Menstrual Cycle 2

Figure 19.14
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Menopause

Menopause
• time when ovaries secrete less hormones and number of
follicles in ovaries is low
• menstrual cycle and ovulation are less regular
• hot flashes, fatigue, irritability may occur
• estrogen replacement therapy may be used to decreases
side effects

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Female Sexual Behavior 1

• Sexual drive in females, like sexual drive in males, is


dependent on hormones.
• Testosterone-like hormones, and possibly estrogen, affect
brain cells (especially in the area of the hypothalamus)
influence sexual behavior.
• Testosterone-like hormones are produced primarily in the
adrenal cortex.

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Female Sexual Behavior 2

• Psychological factors also play a role in sexual behavior.


• The sensory and motor neural pathways involved in
controlling female sexual responses are similar to those
found in the male.

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Female Sex Act 1

• During sexual excitement, erectile tissue within the clitoris


and around the vaginal opening becomes engorged with
blood.
• The mucous glands within the vestibule secrete small
amounts of mucus, with larger amounts extruded into the
vagina through its wall.
• Stimulation of the female’s genitals during sexual
intercourse and psychological stimuli normally trigger an
orgasm, or climax.

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Female Sex Act 2

• The vaginal and uterine smooth muscle, as well as the


surrounding skeletal muscles, contract rhythmically, and
muscle tension increases throughout much of the body.
• After the sex act, there is a period of resolution, which is
characterized by an overall sense of satisfaction and
relaxation.

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Contraception

• Many methods are used to prevent pregnancy, either by


preventing fertilization (contraception) or by preventing
implantation of the developing embryo.

• There are six main types of birth control. From the most to
least effective they include: (1) long-acting reversible
contraception, (2) sterilization, (3) hormonal methods, (4)
barrier methods, (5) fertility awareness, and (6)
emergency contraception.

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