PAST PAPER'S

SECOND YEAR MBBS

q KABIR MEDICAL COLLEGE

PESHAVWAR
 GANDHARA UNIVCRSITY,PESIIAWAR
Kabir MledicalCollege, Peslhawar
Second Professional MBBS (Part-l) Aunual Exinati0n July 201
Biuchennistry-I|
ime
e Allowcd: 3 Hours
DIRLCTONS
Pessession &nse uf AMobiles &vther Electronic accessaries re strictk pruhibited duting
fhe vusintian &cen tead toCnceltution of Paper ns well as ExaminatioIt n Snpernitende's repir
Note: lnstruçtinns for candidates:
)A:
2) Part!:
1.C.Q. (Önc Best) Compulsery. Time Alloswed: 20 Mintes
Attempt any five questios
2 1lrs 40 Minutes

Q.1. PART -A
M.C.Q.(Onc Best). 20
PART- B
Siort E:ssay Questions
Note: Attempt any FIVE questions.
a. Describe the HMP Shunt with the help of a
D. wriie down the ow chart. What is its significancc? 03
irrevers1ble reaclions of Glycolysis.
3 a
Fnunerate
b Write a notelipoproteins? Describe the nnetabolis of ||DL. 07
on any ONE
Kctogenesis
ii. Carnitine shuttle 07
07
4. a. Describe the synthesis of Cortisel. Write
b. Write down nnechanis1n of action of down its ellcct on Carbolhydrate mctabotisn?
steroid hormone. 06
5. a. Draw fully labelled tlow chart of urea cyclc.
b. Writc notes on any ONE
i. Homocystinuria 06
ii. Formation of Creatinine in human bndy.
O6
6
:Explain various sleps of Protein Synthesis.
b. Describe the salvage pathway for the synthesis ol purne
nclcoides *
7 Write notcs on
i. Electron Transport hain
Oroicacicluria
. Whul is Dietary Referen al e Deline diyus of Dets Releuake:
 GANDHARAUNIVERSITY, PESHAWAR
Kabir Medical College, I'esbuwar
SecondProfessional MBBS (Part )Supplementary Examination Septenber 2018
BiochemistIy 1!
T..owed: 31lours Masiraa Ma 99
DIRECTIONS
Possessin &use of Mohiles &other Ll tronic acessories ure tricly prohiblted during
the Exanmiuton& cm tel to Cancellutionof Puper as well s Exuninution on Superintendent's repurt
isoucivns foy nddG.
) Part A: MCQ(One Bext) Compulsory. Time Alowed: 20 Minutes
2)'art-3: Attempt any five questions.
2 11rs 40) Minutes

PART - A 20
Q.1. M.C.Q.(One Best).
Short Essay Questions

Note: Attenpt any PiVE questions.

Dsrib d yuicsis uf Glijigun fivi glucosc.
U. Discüs the regulation and significance of Gluconcogcnesis.
labelicd fiow chart. 07
a. Explain the steps of Cholesterolsynthesis witis tie leip of fuily 07
b Write a note on Sphingolipidoses
17
n Deseribe the biosyntlesis of Tlyroid hornones in the bwdy. 0?
b. Explain briefly tlhe biochenical funetions of Growth Hormone.
a. Nane essential annino acids. Describe the functions of Glycine in hunan body. 67
b Give an account of Phenylketonria and Albinisn.
6 a. Name the steps involved in replicatioy. Compare the features of replication and 07
transcription. )7
b. Describethe brbakdown of purine nyjcleoties to uric acid.
7 Write notes on
i Inhibitors and Uncopling proteins of flectroin Transport Cham 07
ii. Metabolic Acidosis & itscompensated by the body
08
1 What is the inportance of protcin in lumn diu" Deseile protcin ctorie nnaluuttitia
h Define BMR? Decribe th l.uotectiny MR.
 GANDIARA UNIVERSTTY, PLSHAWAR

MedicalCollege, l'eshawar
Rabir Anmal xaminion August 2036
MBS Pare)
Seeond 'oievsioul
Maxinn ark
IR1CIWNS
duris
oter Ltectroui wessoriesare strictly prohibited re
P'ossessiun &use o/ dlobite .Snperintenden'y
Cuncellutiou f Puper as well sErmin1lim on
4e niMatian cnleudto
Note: lnstrucinRs for candidates:
)Pa-A: M.C.). (One Best) Compulsory. TineAliuweú: 2(! Minutcs
2 IIrs 40 Minutes
Aeonpt any FlVE: qucstiens.

PART-A
).. M.C:Q. (One Best).

Short ssay Questiu:s

Noie: Aucmpt any FIVE questions.
a. aplain the steps of HMPShunt with elotataw clart.
u iIite a nots on Glucost-0-piosplhaie tyoge:c deiteiency (G6PD deficiency)
Enumerate lipoproleins? Describe the metáuoi o! DL..
b. Explain the steps of Ketogen:is with the lclpol tlow ch:rt.
oit Describe the biosynthesis «l thy roid bonm:nes. Ne the dneases usiciled with
d:licieneyofthyroidhormons
. Exptain the elfechs of inerease grOwth honone on bo.

ia. Dran lully labelid tlow chart of Urea cyeie.

b. Nane Glueogenie anino acids. Dewrihe ta lincti sof Glyeme in human hody
Explrin in detail hie poeeSs ofPokarpotw DNA rpacatw
esribe the brcshdown of Pu ie Nucktid toltiK wit.

Eleiron Irnsport Ciain

iletabeic Acidosis Netale A!alois

I'oein C:lorie Muttiti.m

Diehac, Mellit,
lormatim taslolAnnin
 NIAUKIVCRSIRRUAW
istry:l!
Ale: 3 as
ESCT)y

ete: iuiigas for cauiids:

iCQ.Oa: Pst) Comiory. TiRe.J:: 20 irules
Atenpt ay fre qstirs.
2lirs 40Ninales

!3T- A
(1. MCQ.(Üae Best).
PART-S
Short 'say Qucstion:

Ni tuennt any FVE queskons.

J. Outlne t:rectiuns of Krcbs cv. What i its sin:fcerr?
b. Write a note on Glycogen Storag Diszse.
of
a What is B-Oxidation of Faily Acids? Give the rcactions o-Oxidation
Saturated l'atty Acids.
b. Eruncrate L.pid storage diseuse Wrie abriefaccoust on Niemaua-Pick Disese.
a. i'ane the Hyperglyccmic hermones. Wrile a briel 2ccount uf metabolic funciots of ulin.
b Nane any TW0hormones that actvia cAP? Explan thc aiecha.isnuf aciion
of hor1nones via

frescrise tlie metabolic disordes assziated wih lsenevcl.

Write the steps ipvalved ia tÉe synicsi: of Creatiaineand what isits clinicad signii
Decsie t detail the process of Tiatsin
Wrieana on PespiraOry Acidysis &kespiratory Al.alozs.
nethe Inkioiory and Usems fOxilutive Ple phorylation aid we in Li
Trapot (Chain they aut?
i3 ine 4.Desrib: line tritiondinpontance ol lipilia lrnn dat.

Ditrtus lesipiig
 AAWAR
GANDHHARA UNIVERSITY,PESHÁWAR
College, Peshawar (he
Kabir Medical Septmher 2020
ProfessionalMBBS (Part-II) Annual Examination
Second
Biochemistrv-II
Cieetne l.
Maximum Marks:
Time Allowed: 3 Hours
DIRECTIONS
sirictly prohihited during
ossession &use of Mobiles & otlher Electronic accessories are
well as Examination on Superintendent's repor
the Examination &cun lead to Cancellution of Puper as
Note: Instructions for candidates:
1) Part-A: M.C.Q. (One Best) Compulsory. Time Alowed: 20 Minutes
Hrs40 Minutes
2) Part-B: Attempt any FIVE questions. (2
PART-A 20
Q.1. M.C.Q.(One Best).
PART -B
Short Essay Questions 70
Note: Attempt any FIVE questions.
Wo Explain the steps of anaerobic glycolysiswith the help of aflow chart
Discuss the regulation and signiicance of Gluconeogenesis.
Lo a Explain the Biosynthesis of
b. Name ketone bodies. DescribeClholesterol in human body.
reactions involved in ketagenesis. qccbo oet ade acetyl7 C
. 'a. What are second messengers? Describe the biosynthesis of Catecholamines.
b. Write down mechanism of action of Steroid hormone.

a. Name essential amino acids. Write down the functions of Tyrosine in humánbody. 7
tbBescribe the breakdown of Purine Nucleotide to Uric acid.
a. Write a detailed account of Post translational modification of protein. 8
b. Define BMR? Describe thà factors affecting BMR. 6

a. Draw acompletely labeled diagram for electron transport chain with a mention of
coimponents of different conplexes.
b. Write notes on any ONE.
Protein calorie malnutrition
ii. Role ofkidneys in acid base balance.
Q8. a. What is Dietary Reference intake? Define different types of Dietary Reference
b. Write notes on any ONE intake.
i. Anion Gap
ii. Fornation of Creatinine in human bodyv

dyl
 KABIR MEDICAL COLLEGE PESHAWAR
DEPARTMENT OF BIOCHEMISTRY
(27-2-2020)
2" Year MBBS test in AmnoAcid Metabol1sm,
Nucleotide MetablismT HUI
and Nutrition.
Time Aliowed: 1 hrs.
Total Marks: 50.
Note: Attempt ALL Questions Pass Marks. 25

1. a. What is Dietary Reference intake? Define ditferent types of Dietary Reference intake
b. Write a note on
i. Protein Energy Malnutrition (PEM)
ii. Basal Metabolic Rate (BMR)
2. Write short notes on
6
Synthesis &Degradation of Creatine.
Metabolicdisorders of Urea cycle. 6
7
iii. Degradation and re-synthesis of Methionine.
3. a. Describefhe De novo synthesis of gurine nucleutides.
b Explain ith help of flow chart brdakdown of pyrimidine nucleotide.
0-0-0-0-0
DH
T
 KABIR MEDICAL COLLEGE
DEPARTMENT OF BIOCHEMISTRY
PESHAWAR
(09-01 -2i20)
2na Year MBBS test in Acid Base Balance,
Bioenergetics and Carbohydrate Metabolism
Time Alowed: 1 hrs: Attempt all Questions
Total Marks 50.
1. a. Draw aCompletely labeled diagram for electron transport chain with a mention of components
of different complexes. 09
Describe the Principal features of Chemiosmotic theory. 08

a.
Describe.the steps-ofgyeogensytresis and its regulation in-hurman body. 09
Lt. Qutline -the-feactions-of Citric acid.cycle. Whatis its significance? 08

3. Write short notes on

Role of kidneys in Acid base balance 08
Synthesis of Glucose from Pyruvate. 08

0-0-0-0
 GANDHARAUNIVERSITY, PESHAWAR
Kabir Medica! College, Peshawar
Second Professional MBBS (Part-I) Annual Examination September 2020
Biochemistry-II
Time Allowed: 3
Hours Maximum Marks: 90

DIRECTIONS
OSsession &use of Mobiles &other Electronic accessories are strictly prokibited during
ne Exanination & can lead to Cancellution of Paper as well as Exannination on Superintedent's repur.
Note: Instructions for candidates:
1)Part-A: M.C.Q. (One Best) Compulsory. Time Allowed: 20 Minutes
2) Part-B: Attempt any FIVE questions. | 2 Hrs40 Minutes

PART - A
Q.1. M.C.Q. (One Best). 20

PART -B
70
Short Essay Questions
Note: Attempt any FIVE questions.
a. Explain the steps of anaerobic glycolysis with the help of a flow chart.
7
b. Discuss the regulation and significance of Gluconeogenesis.
a. Explain the Biosynthesis of Cholesterol in human body. 13
b. Name ketone bodies. Describe reactions involved in ketogenesis.
a. What are second messengers? Describe the biosynthesis of Catecholamines. 4 7
b. Write down mechanism of action of Steroid hormone. 7

a. Name essential amino acids. Write down the functions of Ty rosine in human body.
b. Describe the breakdown of Purine Nucleotide to Uricacid.
a. Write a detailed account of Post translational modification of protein.
b. Define BMR? Describe the factors affecting BMR. , 6

a. Draw a completely abeled diagram for electron transport chain with a mention of
components of difffrent complexes.
b. Write notes on any ONE.
Protein calorie malnutrition
ii. Role of kidneys in acid base balance.

a.b. What is Dietary Reference intake? Define dilferent types of Dietary Reference intake.
Write notes on any 0NE
i. Anion Gap
ii. Fornation of Creatinine ia thnun body
 Second
GANDHARA
Kabir UNI V ERSI T
Medical College,
Y, PESHAWAR
Professional MBBS Annual Examination
Peshawar
Tihne Allowed: 3 Hours Biochemistry September 2021
Maximum Marks: 90
Possession & use of Mobiles & DIRECTIONS
other
Cancellation ofElectronic
theExamination& can lead to
PaperS accessories
are strictly prohibited
well as Examination on during
Note: Instructions for
candidates:
Superintendeni' s reporl.
1)Part-Á:
2) Part-B:
M.C.Q. (One Best) Compuisory. Time Allowed: 20 Minutes
Atenpt any FIVE questions. 2Hrs 40 Minutes
Q.1. M.C.Q. (One Best). PART-A
20
PART-I
Short Essay Questions 70

Note: Attempt any FIVE questions.

2. a. Describe the HMP Shunt with the help of a flow chart. What is its significance? 08
b. Write down the irreversible reactions of Glycolysis. 06

3. a. Enumerate lipoproteins? Describe themetabolism of VLDL. 08

b. Describe Canitine shuttle and itsrole in B-oxidation. 06

4. a. Describe the synthesis of Cortisol. Write down itseffect on Carbohydrate metabolism? 08

b. Write down mechanis1n of action of steroid hormone. 06

a. Draw fully labelled flow chart of Urea Cycle. 07

b. Write notes on any TWO 07
i. Gout.
(0CAA A ii. Maple Syrup Urine Disease.
ii. Fate Acetyl CoA
6 a. Explain various steps of Protein Synthesis. 08
b. Describe the salvage pathway for the synthesis of Purine Nucleotides 06

Write notes on
Electron Transport Chain 07
Diabetes Mellitus 07

08
a What is the importarnce of Protein in hunan diet? Describe Protein Calorie Malnutrition. 06
b. Define BMR? Describe the factors affecting BMR.
 GANDHARA
Kabir
UNIVERSITY,PESHAWAR
Medical College, Peshawar
Second Professional MBBS Annual Examination October 2022
Time Allowed: 3 Hours
BIOCHEMISTRY
Maximum Marks: 70
DIRECTIONS
Possession & use of Mobiles & other Electron0c accessories ure stricrly prohiblted during
lhe Examination & can lead to Cancellation off Paper as well as Examination on Superintendent's report.
Note: Instructions for candidates :
1)Part-A: M.C.Q. (One Best) Compulsory. Time Allowed: 20 Minutes
2) Part-B: Attempt any FIVEquestions. [2 Hrs. 40 Minutes

PART -A 20
Q.1. M.C.Q. (One Best).

PART- B
Short Essay Questions 50

Note: Attempt any FIVE questions.

VQ2. Describe the various steps of Citric acid cycle with the help of aflow chart. 10

V. Q3. Enumerate lipoproteins? Describe the metabolism of VLDL. 10

Q4: Name ketogenic amino acids. Describe the functions of Glycine in human body.L 10

Q5. Describe the synthesis of Cortisol. Write down its effect on Carbohydrate metabolism? 10

Q6 Describe the digestion &absorption of Lipids in human body. 10

Describe in detailthe process of Prokaryotic DNA replication. 10

Q3. Name High Energy Compounds. Draw fully labelled diagram of Electron transport chain. 10
 GANDHARA UNIVERSITY,PESHAWAR
Kabir MedicalCollege, Peshawar
Second Professional MBBS Annual Examination August 2023
BIOCHEMISTRY
Time Alowed: 3 Hours Maximum Marks: 70

DiRECTIONS
Possessior & se of Mobiles& other Electronic accessories are strictly prohibiued during
the Examination & can lead to Cancellation of Paperas well as Examination on Superintendent's report.
Note: Instructions for candidates:
Time Allowed: 20 Minutes
1) Part-A: M.C.Q. (One Best) Compulsory.
2) Part-B: Attempt any FIVE questions. [2 Hrs. 4O Minutes ]

PART- A 20
Q.1. M.C.Q. (One Best).

PART-B

Short Essay Questions 50

Note: Attempt any FIVEquestions.

Explain the steps of anaerobic glycolysis with the help of fully labelled flow chart.
10

03) What is B-Oxidation of Fatty Acids? Give the reactions of ß-Oxidation of Saturated Fatty Acids 10
10
Describe the breakdown of purine nucleotides to Uric acid.
Describe the synthesis of Cortisol, Write down its effect on Carbohy drate metabolism? 10

Q6. Describe the digestion & absorption of Proteins in human body.

Q7. Write notes on 05
a. Post translational modification of Protein.
b. Degradation of Branched chain Amino Acids.
10
Q8. What is Dietary Reference intake?7 Define different ty pes of Dietary Reference intake.