17012024 Assignment # 01 Foundation Batch

ORGANIC CHEMISTRY
(Topic : AMINO ACIDS)
(for JEE-Mains & Advanced 2025)
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01. At low pH, an amino acid exists as :
+ +
*(a) H3 N CHRCOOH (b) H3 N CHRCOO– (c) H2NCHRCOO– (d) H2NCHRCOOH
02. At high pH, an amino acid exists as :
+ +
(a) H3 N CHRCOOH (b) H3 N CHRCOO– *(c) H2NCHRCOO– (d) H2NCHRCOOH
+ +
03. If Ka1 and Ka2 are the ionization constants of H3 N CHRCOOH and H3 N CHRCOO–,
respectively, the pH of the solution at the isoelectric point is :
(a) pH=pK 0a1 +pK 0a2 (b) pH=(pK 0a1 pK 0a2 )1/2
(c) pH=(pK 0a1 +pK 0a2 )1/2 *(d) pH=(pK 0a1 +pK a2
0
)/2
04. You have a mixture of three amino acids: E (pI=3.2), Y (pI=5.7) & K (pI=9.7)
Under electrophoresis at pH=7.7, in which direction will each component of the
mixture move ?
(a) E to anode; Y & K to cathode (b) E to anode; Y stationary; K to cathode
(c) E to cathode; Y stationary; K to anode *(d) E & Y to anode; K to cathode
05. A protein 'X' with molecular weight of 70,000 u, on hydrolysis gives amino acids.
One of these amino acid is :

CH3
l
(a) NH2 –CH2 – C H –CH2 CH2 COOH *(b) CH3 – C H –CH2 – CH – COOH
l l
CH3 NH2
CH3 CH3
l l
CH3 – C H – CH – CH2 COOH CH3 – CH – CH2 – CH2 COOH
(c) l (d) l
NH2 NH2

06. The amino acid at low pH exists as :

(a) (b) *(c) (d)

07. In an amino acid, the carboxylic group ionises at pka1 = 2.34 and ammonium ion at
pka2 = 9.60. The iso electric point of the amino acid is at pH :
*(a) 5.97 (b) 2.34 (c) 9.60 (d) 6.97
08. The given structure of -amino acid will exist at which pH ?
R–CH–COOH
NH 3
+
(a) 7 (b) 14 *(c) 4.3 (d) 12

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09. The amino acid at high pH exists as :

(a) (b)

(c) *(d)

10. Which of the following statements most correctly defines the isoelectric point?
(a) the pH at which all molecular species are ionized and that carry the same charge.
(b) the pH at which all molecular species are neutral and uncharged.
(c) the pH at which half the molecular species are ionized (charged) and the other
half unionized.
*(d) the pH at which negatively and positively charged molecular species are present
in equal concentration.
11. The given structure of -amino acid will exist at which pH ?
COOH

NH3 – CH – HH
R
(a) 7 (b) 14 *(c) 0 (d) 12
12. How many acidic groups are present in given amino acid ?

NH 3–CH–CH 2–CH 2–CO 2H
CO 2–
*(a) 2 (b) 4 (c) 3 (d) 1
13. What would be the net charge on the given amino acid at pH = 14
COOH O
H2N–CH–(CH 2)4–C–OH
(a) – 1 *(b) – 2 (c) + 1 (d) + 2

14. In the compound the order of acidity of positions X, Y and Z

is :

*(a) X > Y > Z (b) X > Z > Y (c) Z > X > Y (d) Y > Z > Z

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Integer Type #
15. The pKa values for the three acidic group P,Q,R are 4.3, 9.7 and 2.2 respectively

Calculate the isoelectric point of the amino acid ?

Ans : 3.25
16. A decapeptide (Mol. Wt. 796) on complete hydrolysis gives glycine (Mol. Wt. 75),
alanine and phenylalanine. Glycine contributes 47.0% to the total weight of the
hydrolysed products. The number of glycine units present in the decapeptide is ?
Ans : 6

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