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Test Method CTS
Test Method CTS
The Hand Elevation test is a new provocative test for the diagnosis of carpal tunnel syndrome. We
have investigated the sensitivity and specificity of this test in 48 patients with a clinical diagnosis of
carpal tunnel syndrome and compared it to Tinel’s and Phalen’s tests. The Hand Elevation test was
found to be 88% sensitive and 98% specific. This test is a simple, reproducible provocative test
which is easily employed in conjunction with other known tests to assist in the diagnosis of carpal
tunnel syndrome.
Journal of Hand Surgery (British and European Volume, 2005) 30B: 4: 361–364
Keywords: hand elevation test, carpal tunnel syndrome, diagnostic tests for carpal tunnel syndrome
361
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362 THE JOURNAL OF HAND SURGERY VOL. 30B No. 4 AUGUST 2005
followed by the affected side (the side which was due to Tinel’s test
undergo surgery first in bilateral cases). Patients were Percussion was performed over the course of the median
informed of the purpose of the examination and verbal nerve just proximal to and over the carpal tunnel with
consent obtained. the wrist in a relaxed position (201 of extension). If
The requirement for postoperative follow-up by asymptomatic on first tapping, this was repeated up to
phone and the method of the Hand Elevation test were six occasions. If still asymptomatic the test was negative.
fully explained. The patients were subsequently tele- A positive test was associated with paraesthesiae in the
phoned 3 months postoperatively, asked about their median nerve distribution, or an electric shock-like
symptoms and instructed to perform the Hand Eleva- sensation passing into the hand or forearm, as originally
tion test. described by Tinel, although this test was initially used
to follow the regeneration of an injured nerve (Tinel,
1915). As a consequence, when used in carpal tunnel
Control group syndrome, this test is often called the Nerve Percussion
test.
During the same period, an equivalent number of
patients with lower limb injuries were randomly selected Phalen’s test
and evaluated in the same manner. Any patient in this Patients fully palmar flexed the wrist with the elbow in
group with symptoms of carpal tunnel syndrome, full extension and the forearm in pronation. The test
radiculopathy, concomitant neck injury, stroke, diabetes was negative if the patient was asymptomatic after
mellitus or any type of peripheral neuropathy was 1 minute. A positive test occurred if the symptoms with
excluded. Forty-seven patients were recruited. One hand which the patient had presented were reproduced.
was excluded because it had suffered a concomitant Phalen originally described this test with the elbow in
injury, leaving 93 hands. The mean age of the controls flexion (Phalen, 1966). However many believe that
was 57 (range 23–94) years. Twenty-six (55%) were men flexing the elbow can put extra pressure on the median
and 21 (45%) were women. The purpose of the study nerve at more proximal levels.
was explained and verbal consent obtained before the
Hand Elevation, Tinel’s and Phalen’s tests were
performed on both hands. A number was allocated to Statistical analysis
each hand in the control group and, by using the table of
random numbers, 47 hands were recruited. Each time Sample size was calculated prospectively on the basis of
that a hand was selected, the contralateral hand was 90% power of the test statistic with a 0.05 two-sided
excluded from the population, to ensure employment of significance level to detect the difference between group
only one hand from each individual. 1 with proportion of 0.8 positive HET (study group) and
group 2 with proportion of 0.05 (control group).
The calculated sensitivities and specificities of the
Provocative tests three tests were based on calculations of confidence
intervals (including the results from the control group).
Two standard provocative tests (Tinel’s and Phalen’s) McNemar’s Test Statistic (with continuity corrected
were used and compared with the Hand Elevation test. P-values) was used to study the differences in the
The order of testing was the Hand Elevation test, Tinel’s proportions of positive results for the three tests in
test then Phalen’s test, with 2 minutes rest for complete patients with affected hands and the difference in hand
recovery between the tests. elevation test pre- and postoperatively (excluding the
control group).
Table 1—Sensitivity, specificity, positive predictive value, negative predictive value and efficiency of the three provocative tests (based on preop patients
group and the control group)
Sensitivity (95% C.I.) Specificity (95% C.I.) PPV (95% C.I.) NPV (95% C.I.) Efficiency (95% C.I.)
PPV, positive predictive value; NPV, negative predictive value; C.I., confidence interval.
Table 1 compares the sensitivities, specificities, The pathophysiology of carpal tunnel syndrome is not
positive predictive values, negative predictive values entirely clear. However, there is evidence of higher
and efficiencies of these tests. pressure in the carpal tunnels of patients as compared to
A statistically significant difference was found be- the normal population (Gelberman et al., 1981). Increased
tween pre- and postoperative Hand Elevation test carpal tunnel pressure will compress the nerve and may
results (Po0:0005). We found the Hand Elevation test compromise the microcirculation of the nerve by com-
and Phalen’s test were significantly more sensitive and pressing vessels in the perineurium. We think that it is
specific than Tinel’s test (P ¼ 0:0003 for Phalen’s test probable that the Hand Elevation test further reduces the
and P ¼ 0:00003 for the Hand Elevation test). However, blood supply of an already compromised nerve by
no significant difference was seen between sensitivities reducing local blood pressure and, thus, reproduces the
and specificities of Phalen’s test and the Hand Elevation symptoms. In the Hand Elevation test, elevation of the
test (P ¼ 0:56). hand above the head and observation of the reproduction
of symptoms are all that is necessary to determine a
negative or positive test. It is easily performed, has a high
interobserver reliability, is reproducible and does not need
DISCUSSION
any additional instruments in the clinic. All of the patients
Carpal tunnel syndrome can usually be diagnosed in the current study performed it without difficulty.
clinically and, in our unit, the commonly used provocative However, we are aware that some patients with restricted
tests are Tinel’s (or the Nerve Percussion) and Phalen’s shoulder function might find it difficult to hold the hand
tests. Electrodiagnostic studies may be helpful in equivocal above the head, in which case the test could not be used. A
cases, but if the symptoms and clinical signs are suggestive similar problem also arises when carrying out Phalen’s test
of carpal tunnel syndrome they may add little but cost to in patients with limited wrist flexion. Arm elevation may
the management and outcome (Concannon et al., 1997). aggravate a Thoracic Outlet Syndrome. However, this
Unfortunately, the sensitivity and specificity of Tinel’s usually produces symptoms in the ulnar two fingers and
and Phalen’s tests varies in different studies (sensitivity along the medial aspect of the forearm, whereas the Hand
of 48–77% and specificity of 47–84% for Tinel’s test; Elevation test for carpal tunnel syndrome should produce
sensitivity of 28–61% and specificity of 80–94% for symptoms in the radial side of the hand to be positive.
Phalen’s test) (González Del Pino et al., 1997). This One previous paper has described the Hand Elevation
variability may reflect the fact that the results of these test and reported its sensitivity as 76% and its specificity
tests depend to a large degree on how they are as 99% (Ahn, 2001). However, this study of 200 patients
performed and the examination technique can vary was confined to the female population and no post-
between examiners (especially for Tinel’s test). As a operative data was presented. The current study has
result, they have low interobserver reliability and there is recorded better sensitivity and the same specificity as the
a need for more valid tests. In our study, we performed previous study and shown that it applies to both the
the Phalen’s test slightly differently to the original male and female population.
description, with the elbow in extension instead of We employed the test postoperatively to compare
flexion. Done in this way, the observer presses the with pre-operative results and found that the Hand
median nerve only at the level of the carpal tunnel. The Elevation test and Phalen’s test had superior sensitivity
results we obtained from Phalen’s test are similar to the and specificity to Tinel’s test. We recommend its use, as
previously reported results in the literature. Tinel’s test a simple and reliable, additional provocative test in the
was carried out as described by Tinel (1915). diagnosis of carpal tunnel syndrome.
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364 THE JOURNAL OF HAND SURGERY VOL. 30B No. 4 AUGUST 2005